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Term:pristinamycin IIA
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Accession:CHEBI:9997 term browser browse the term
Definition:A macrolide that is (together with pristinamycin IA) a component of pristinamycin, an oral streptogramin antibiotic produced by Streptomyces pristinaespiralis. Pristinamycin exhibits bactericidal activity against Gram positive organisms including methicillin-resistant Staphylococcus aureus.
Synonyms:exact_synonym: (3R,4R,5E,10E,12E,14S)-14-hydroxy-3-isopropyl-4,12-dimethyl-8,9,14,15,24,25-hexahydro-1H,3H,22H-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone
 related_synonym: Formula=C28H35N3O7;   InChI=1S/C28H35N3O7/c1-17(2)26-19(4)9-10-24(34)29-11-5-7-18(3)13-20(32)14-21(33)15-25-30-22(16-37-25)27(35)31-12-6-8-23(31)28(36)38-26/h5,7-10,13,16-17,19-20,26,32H,6,11-12,14-15H2,1-4H3,(H,29,34)/b7-5+,10-9+,18-13+/t19-,20-,26-/m1/s1;   InChIKey=DAIKHDNSXMZDCU-FQTGFAPKSA-N;   Mikamycin A;   Ostreogrycin a;   SMILES=CC(C)[C@H]1OC(=O)C2=CCCN2C(=O)c2coc(CC(=O)C[C@H](O)\\C=C(/C)\\C=C\\CNC(=O)\\C=C\\[C@H]1C)n2;   Streptogramin A;   Virginiamycin M1;   Virginiamycin factor M1
 alt_id: CHEBI:46395
 xref: CAS:21411-53-0 "ChemIDplus";   CAS:21411-53-0 "KEGG COMPOUND";   DrugBank:DB01669;   KEGG:C11299;   PDBeChem:VIR;   PMID:15480455 "Europe PMC";   PMID:24324222 "Europe PMC";   PMID:24687494 "Europe PMC";   PMID:25223995 "Europe PMC";   PMID:3096930 "Europe PMC";   PMID:5905315 "Europe PMC";   Reaxys:71867 "Reaxys";   Wikipedia:Pristinamycin_IIA

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Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        antimicrobial agent 17211
          macrolide antibiotic 324
            pristinamycin IIA 0
              virginiamycin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic group 18413
                              organic divalent group 18404
                                organodiyl group 18404
                                  carbonyl group 18293
                                    carbonyl compound 18293
                                      carboxylic acid 17960
                                        carboacyl group 17072
                                          univalent carboacyl group 17072
                                            carbamoyl group 16801
                                              carboxamide 16801
                                                alpha,beta-unsaturated carboxylic acid amide 4753
                                                  enamide 4753
                                                    pristinamycin IIA 0
                                                      virginiamycin 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.