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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:diabetic encephalopathy
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Accession:DOID:0050850 term browser browse the term
Definition:A brain disease that is characterized by functional impairment of cognition, cerebral signal conduction, neurotransmission and synaptic plasticity, and underlying structural pathology associated with diabetes. (DO)
Synonyms:exact_synonym: diabetic encephalopathies
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
diabetic encephalopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:23529380, PMID:24291733 RGD:7244255, RGD:8553040 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G App amyloid beta precursor protein treatment IEP associated with type 2 diabetes mellitus RGD PMID:28885995 RGD:13782056 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Dusp1 dual specificity phosphatase 1 IEP associated with Diabetes Mellitus, Experimental RGD PMID:17601561 RGD:7771546 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:26970304 RGD:13792771 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Ide insulin degrading enzyme ISO associated with type 2 diabetes mellitus RGD PMID:27306699 RGD:13792796 NCBI chr 1:255,914,465...256,014,168
Ensembl chr 1:255,914,447...256,013,495
JBrowse link
G Ngf nerve growth factor treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23528019 RGD:7242845 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Ngfr nerve growth factor receptor treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:23528019 RGD:7242845 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:24291733 RGD:8553040 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16023
    disease of anatomical entity 15278
      endocrine system disease 4997
        diabetes mellitus 1371
          Diabetes Complications 405
            diabetic encephalopathy 8
Path 2
Term Annotations click to browse term
  disease 16023
    Nutritional and Metabolic Diseases 4727
      disease of metabolism 4727
        acquired metabolic disease 2786
          carbohydrate metabolism disease 1757
            glucose metabolism disease 1757
              diabetes mellitus 1371
                Diabetes Complications 405
                  diabetic encephalopathy 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.