ONTOLOGY REPORT - ANNOTATIONS


Term:pre-malignant neoplasm
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Accession:DOID:0060071 term browser browse the term
Definition:Pathological processes that tend eventually to become malignant. (From Dorland, 27th ed)
Synonyms:exact_synonym: Precancerous Condition;   Precancerous Conditions;   Preneoplastic Condition;   Preneoplastic Conditions
 primary_id: MESH:D011230;   RDO:0005175
For additional species annotation, visit the Alliance of Genome Resources.


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pre-malignant neoplasm term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 3 10,041,820 10,145,076 RGD:11554173
G Ace angiotensin I converting enzyme JBrowse link 10 94,170,766 94,213,831 RGD:11039027
G Actc1 actin, alpha, cardiac muscle 1 JBrowse link 3 105,507,403 105,512,939 RGD:11554173
G Acy1 aminoacylase 1 JBrowse link 8 115,134,792 115,140,171 RGD:11554173
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:11554173
G Aldh2 aldehyde dehydrogenase 2 family member JBrowse link 12 40,466,418 40,498,813 RGD:11554173
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 JBrowse link 5 158,090,238 158,115,725 RGD:11554173
G Anxa4 annexin A4 JBrowse link 4 118,538,775 118,595,591 RGD:11554173
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:11554173
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:1599367
G Atp5f1b ATP synthase F1 subunit beta JBrowse link 7 2,504,708 2,511,748 RGD:11554173
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:13792594
G Bcat2 branched chain amino acid transaminase 2 JBrowse link 1 101,553,900 101,572,103 RGD:11554173
G Bid BH3 interacting domain death agonist JBrowse link 4 153,439,812 153,465,247 RGD:13792594
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:13792594
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:13792594
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:13792594
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:11554173
G Ccdc134 coiled-coil domain containing 134 JBrowse link 7 123,362,471 123,376,930 RGD:11554173
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:11554173
G Cdh1 cadherin 1 JBrowse link 19 38,768,467 38,838,395 RGD:11554173
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:10043364
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:1600820
RGD:11554173
G Cebpa CCAAT/enhancer binding protein alpha JBrowse link 1 91,363,492 91,366,164 RGD:11554173
G Cfl1 cofilin 1 JBrowse link 1 220,869,805 220,873,337 RGD:11554173
G Chn2 chimerin 2 JBrowse link 4 84,423,708 84,452,989 RGD:11554173
G Cish cytokine inducible SH2-containing protein JBrowse link 8 116,054,547 116,059,494 RGD:11554173
G Cog4 component of oligomeric golgi complex 4 JBrowse link 19 43,358,057 43,391,828 RGD:11554173
G Col23a1 collagen type XXIII alpha 1 chain JBrowse link 10 34,846,618 34,934,991 RGD:11554173
G Cps1 carbamoyl-phosphate synthase 1 JBrowse link 9 74,113,437 74,236,274 RGD:11554173
G Ddx54 DEAD-box helicase 54 JBrowse link 12 41,469,642 41,484,887 RGD:11554173
G Dpp10 dipeptidyl peptidase like 10 JBrowse link 13 39,430,590 41,173,706 RGD:11554173
G Efnb2 ephrin B2 JBrowse link 16 86,631,151 86,672,050 RGD:11554173
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:11554173
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 JBrowse link 16 68,954,860 68,968,248 RGD:11554173
G Ergic3 ERGIC and golgi 3 JBrowse link 3 151,553,567 151,563,318 RGD:11554173
G Exosc2 exosome component 2 JBrowse link 3 10,151,734 10,161,997 RGD:11554173
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:13792594
G Foxm1 forkhead box M1 JBrowse link 4 161,685,236 161,697,633 RGD:11554173
G Fth1 ferritin heavy chain 1 JBrowse link 1 226,030,940 226,033,228 RGD:11554173
G Gjb1 gap junction protein, beta 1 JBrowse link X 71,272,030 71,279,973 RGD:11554173
G Gsta4 glutathione S-transferase alpha 4 JBrowse link 8 85,497,557 85,514,732 RGD:11554173
G Gsto1 glutathione S-transferase omega 1 JBrowse link 1 267,607,437 267,617,387 RGD:11554173
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:10401933
RGD:11554173
RGD:10401944
RGD:10401942
G Hadh hydroxyacyl-CoA dehydrogenase JBrowse link 2 236,353,445 236,395,067 RGD:11554173
G Higd2a HIG1 hypoxia inducible domain family, member 2A JBrowse link 17 10,558,714 10,559,638 RGD:11554173
G Hras HRas proto-oncogene, GTPase JBrowse link 1 214,178,404 214,181,841 RGD:11554173
G Ift88 intraflagellar transport 88 JBrowse link 15 37,690,417 37,786,855 RGD:11554173
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:11554173
G Igfbp1 insulin-like growth factor binding protein 1 JBrowse link 14 87,448,716 87,453,783 RGD:11554173
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:11554173
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:10403043
G Irs1 insulin receptor substrate 1 JBrowse link 9 88,033,668 88,086,488 RGD:11554173
G Krt8 keratin 8 JBrowse link 7 143,596,511 143,603,745 RGD:11554173
G Map2k7 mitogen activated protein kinase kinase 7 JBrowse link 12 2,546,278 2,555,310 RGD:11554173
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:11554173
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 10 35,333,859 35,374,364 RGD:2304231
RGD:11554173
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:11554173
G Mgmt O-6-methylguanine-DNA methyltransferase JBrowse link 1 209,237,255 209,464,189 RGD:11554173
G Mir125a microRNA 125a JBrowse link 1 59,704,827 59,704,911 RGD:11554173
G Mir145 microRNA 145 JBrowse link 18 56,969,907 56,969,994 RGD:11554173
G Mir151 microRNA 151 JBrowse link 7 114,485,547 114,485,643 RGD:11554173
G Mir196b microRNA 196b JBrowse link 4 82,199,056 82,199,140 RGD:11554173
G Mir200b microRNA 200b JBrowse link 5 173,490,144 173,490,238 RGD:11554173
G Mir211 microRNA 211 JBrowse link 1 125,042,119 125,042,224 RGD:11554173
G Mir212 microRNA 212 JBrowse link 10 62,014,702 62,014,812 RGD:11554173
G Mir26b microRNA 26b JBrowse link 9 81,675,275 81,675,359 RGD:11554173
G Mir290 microRNA 290 JBrowse link 1 64,538,705 64,538,785 RGD:11554173
G Mir30a microRNA 30a JBrowse link 9 29,542,635 29,542,705 RGD:11554173
G Mir30d microRNA 30d JBrowse link 7 109,286,463 109,286,544 RGD:11554173
G Mir324 microRNA 324 JBrowse link 10 56,621,126 56,621,208 RGD:11554173
G Mir331 microRNA 331 JBrowse link 7 34,881,095 34,881,190 RGD:11554173
G Mir349 microRNA 349 JBrowse link 7 130,146,518 130,146,614 RGD:11554173
G Mir409 microRNA 409 JBrowse link 6 133,893,419 133,893,495 RGD:11554173
G Mir652 microRNA 652 JBrowse link X 114,002,534 114,002,614 RGD:11554173
G Mir92b microRNA 92b JBrowse link 2 188,541,034 188,541,116 RGD:11554173
G Mir98 microRNA 98 JBrowse link X 21,583,875 21,583,982 RGD:11554173
G Mir99b microRNA 99b JBrowse link 1 59,704,216 59,704,285 RGD:11554173
G Mirlet7b microRNA let-7b JBrowse link 7 126,590,627 126,590,711 RGD:11554173
G Mirlet7d microRNA let-7d JBrowse link 17 16,419,980 16,420,077 RGD:11554173
G Mmp7 matrix metallopeptidase 7 JBrowse link 8 5,893,253 5,900,965 RGD:9685350
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:11554173
G Muc1 mucin 1, cell surface associated JBrowse link 2 188,543,137 188,547,874 RGD:11554173
G Muc2 mucin 2, oligomeric mucus/gel-forming JBrowse link 1 214,663,929 214,693,197 RGD:7349371
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:10413878
G Nop16 NOP16 nucleolar protein JBrowse link 17 10,559,811 10,564,728 RGD:11554173
G Npepo aminopeptidase O JBrowse link 17 507,389 825,062 RGD:11554173
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 JBrowse link 13 89,585,072 89,591,278 RGD:11554173
G Pbld1 phenazine biosynthesis-like protein domain containing 1 JBrowse link 20 27,103,300 27,118,650 RGD:11554173
G Pebp1 phosphatidylethanolamine binding protein 1 JBrowse link 12 45,026,948 45,031,148 RGD:11554173
G Phb prohibitin JBrowse link 10 83,476,107 83,488,878 RGD:11554173
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase JBrowse link 20 8,165,423 8,169,557 RGD:11554173
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D JBrowse link 10 72,909,550 72,945,884 RGD:1599171
G Prickle2 prickle planar cell polarity protein 2 JBrowse link 4 124,238,167 124,584,176 RGD:11554173
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 2 54,857,688 54,893,404 RGD:11554173
G Prkg1 protein kinase cGMP-dependent 1 JBrowse link 1 248,982,039 250,300,952 RGD:11554173
G Psca prostate stem cell antigen JBrowse link 7 116,090,189 116,091,955 RGD:11554173
G Psd2 pleckstrin and Sec7 domain containing 2 JBrowse link 18 28,781,267 28,832,429 RGD:11554173
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:11554173
G Serpinb3 serpin family B member 3 JBrowse link 13 27,186,701 27,193,211 RGD:11554173
G Sftpd surfactant protein D JBrowse link 16 18,753,535 18,766,100 RGD:4143498
G Sirpa signal-regulatory protein alpha JBrowse link 3 122,113,735 122,152,478 RGD:11554173
G Six3 SIX homeobox 3 JBrowse link 6 8,886,730 8,891,094 RGD:11554173
G Slc52a3 solute carrier family 52 member 3 JBrowse link 3 147,503,266 147,517,935 RGD:11554173
G Smad3 SMAD family member 3 JBrowse link 8 68,569,530 68,678,349 RGD:12903951
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:12903951
G Socs4 suppressor of cytokine signaling 4 JBrowse link 15 24,056,383 24,070,868 RGD:11554173
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:11554173
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:8694319
RGD:11554173
G Stat5a signal transducer and activator of transcription 5A JBrowse link 10 88,764,732 88,789,060 RGD:11554173
G Suv39h1 suppressor of variegation 3-9 homolog 1 JBrowse link X 146,532,002 146,533,538 RGD:9586726
G Tff3 trefoil factor 3 JBrowse link 20 9,850,800 9,855,481 RGD:7349371
G Tmem132d transmembrane protein 132D JBrowse link 12 31,934,343 32,607,768 RGD:11554173
G Tnk2 tyrosine kinase, non-receptor, 2 JBrowse link 11 71,348,726 71,388,520 RGD:11554173
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:11554173
G Tpm4 tropomyosin 4 JBrowse link 16 19,385,810 19,399,851 RGD:11554173
G Trio trio Rho guanine nucleotide exchange factor JBrowse link 2 80,471,398 80,769,313 RGD:11554173
G Trit1 tRNA isopentenyltransferase 1 JBrowse link 5 140,711,943 140,756,893 RGD:11554173
G Tsc2 TSC complex subunit 2 JBrowse link 10 13,962,006 13,996,684 RGD:11554173
G Ttll9 tubulin tyrosine ligase like 9 JBrowse link 3 148,426,008 148,485,370 RGD:11554173
G Uqcr11 ubiquinol-cytochrome c reductase, complex III subunit XI JBrowse link 7 12,171,146 12,175,838 RGD:11554173
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:11554173
G Wscd1 WSC domain containing 1 JBrowse link 10 58,330,711 58,372,966 RGD:11554173
G Yif1a Yip1 interacting factor homolog A, membrane trafficking protein JBrowse link 1 220,470,070 220,474,131 RGD:11554173
G Zbtb20 zinc finger and BTB domain containing 20 JBrowse link 11 62,014,925 62,561,113 RGD:11554173
G Zbtb8os zinc finger and BTB domain containing 8 opposite strand JBrowse link 5 147,535,584 147,547,252 RGD:11554173
Aberrant Crypt Foci term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apc APC regulator of WNT signaling pathway JBrowse link 18 27,011,710 27,106,323 RGD:11554173
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:11554173
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:13210754
RGD:13432056
G Gcg glucagon JBrowse link 3 48,442,635 48,451,650 RGD:11554173
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:13210771
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:13210776
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:13210776
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:13432056
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:13432080
actinic keratosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 JBrowse link 1 256,382,861 256,386,729 RGD:13782258
G Oca2 OCA2 melanosomal transmembrane protein JBrowse link 1 114,661,970 114,987,433 RGD:9491831
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:7394827
adenocarcinoma in situ term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fancf FA complementation group F JBrowse link 1 107,229,516 107,232,321 RGD:11049137
breast carcinoma in situ term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Igf2r insulin-like growth factor 2 receptor JBrowse link 1 48,176,095 48,264,482 RGD:2311631
cervix uteri carcinoma in situ term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adam9 ADAM metallopeptidase domain 9 JBrowse link 16 71,810,377 71,887,926 RGD:2325246
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:2298889
G Brca1 BRCA1, DNA repair associated JBrowse link 10 89,394,821 89,455,093 RGD:2298942
G Cadm1 cell adhesion molecule 1 JBrowse link 8 51,858,906 52,200,591 RGD:2289089
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:2293574
G Ccne1 cyclin E1 JBrowse link 1 94,485,830 94,495,112 RGD:2293574
G Ccng1 cyclin G1 JBrowse link 10 25,903,925 25,910,298 RGD:2316022
G Cd46 CD46 molecule JBrowse link 13 113,786,525 113,818,741 RGD:2293549
G Cdh1 cadherin 1 JBrowse link 19 38,768,467 38,838,395 RGD:2289490
G Cdk4 cyclin-dependent kinase 4 JBrowse link 7 70,345,971 70,352,689 RGD:2293574
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:8662446
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:2293574
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:2296058
RGD:2289676
RGD:2289675
RGD:2296054
G Cdkn2a_v1 cyclin-dependent kinase inhibitor 2A, variant 1 RGD:2289675
RGD:2289676
G Cdkn2b cyclin-dependent kinase inhibitor 2B JBrowse link 5 107,834,353 107,857,428 RGD:2289695
G Csf1r colony stimulating factor 1 receptor JBrowse link 18 56,414,493 56,458,300 RGD:2299119
G Ctnna1 catenin alpha 1 JBrowse link 18 27,923,229 28,055,972 RGD:2289797
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:2290052
G Hdac1 histone deacetylase 1 JBrowse link 5 147,716,664 147,743,723 RGD:2306200
G Hdac2 histone deacetylase 2 JBrowse link 20 43,084,870 43,108,198 RGD:2306200
G Hdac6 histone deacetylase 6 JBrowse link X 15,295,372 15,316,673 RGD:2306200
G Igfbp3 insulin-like growth factor binding protein 3 JBrowse link 14 87,457,647 87,465,374 RGD:2290021
RGD:2290004
G Mgp matrix Gla protein JBrowse link 4 170,856,783 170,860,105 RGD:2293584
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:2293515
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:2290402
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:2293515
G Mthfr methylenetetrahydrofolate reductase JBrowse link 5 164,844,642 164,864,360 RGD:11554173
G Phb prohibitin JBrowse link 10 83,476,107 83,488,878 RGD:2292398
G Pou4f1 POU class 4 homeobox 1 JBrowse link 15 88,618,255 88,622,712 RGD:11554173
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:2298701
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:2299119
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:2299896
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:2298759
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:2306230
RGD:2306232
RGD:2314703
G Skp2 S-phase kinase associated protein 2 JBrowse link 2 58,506,146 58,534,211 RGD:2315036
G Srsf1 serine and arginine rich splicing factor 1 JBrowse link 10 75,334,200 75,341,197 RGD:11039410
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:2298536
RGD:2291916
G Terc telomerase RNA component JBrowse link 2 116,432,723 116,433,110 RGD:2291968
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:2291985
G Thrb thyroid hormone receptor beta JBrowse link 15 8,890,578 9,239,815 RGD:2315099
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:2301099
G Top2a DNA topoisomerase II alpha JBrowse link 10 86,901,467 86,930,947 RGD:2315126
G Tp63 tumor protein p63 JBrowse link 11 78,234,853 78,456,559 RGD:2315435
G Tp73 tumor protein p73 JBrowse link 5 171,355,876 171,415,354 RGD:2290589
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:2315456
G Xiap X-linked inhibitor of apoptosis JBrowse link X 128,409,425 128,455,786 RGD:2315850
De Sanctis-Cacchione Syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc6 ERCC excision repair 6, chromatin remodeling factor JBrowse link 16 8,734,028 8,804,610 RGD:7240710
RGD:8554872
RGD:11554173
ductal carcinoma in situ term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:10053629
G Ang angiogenin JBrowse link 15 28,022,926 28,028,636 RGD:2325702
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:7421537
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:1643341
G Areg amphiregulin JBrowse link 14 18,521,921 18,531,179 RGD:2292664
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:2289659
G Birc5 baculoviral IAP repeat-containing 5 JBrowse link 10 106,856,097 106,864,419 RGD:2293106
G Bnip3 BCL2 interacting protein 3 JBrowse link 1 211,248,098 211,265,282 RGD:7483575
G Brca2 BRCA2, DNA repair associated JBrowse link 12 503,660 544,754 RGD:2289048
G Car9 carbonic anhydrase 9 JBrowse link 5 59,008,277 59,015,535 RGD:11554173
G Casp6 caspase 6 JBrowse link 2 235,341,326 235,353,715 RGD:2301339
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:2289132
G Ccnd2 cyclin D2 JBrowse link 4 159,674,885 159,697,207 RGD:2289156
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:2289659
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 10 86,367,596 86,391,728 RGD:2289981
RGD:2289931
G Erbb3 erb-b2 receptor tyrosine kinase 3 JBrowse link 7 2,989,202 3,010,610 RGD:2289952
G Erbb4 erb-b2 receptor tyrosine kinase 4 JBrowse link 9 75,021,790 76,178,936 RGD:2289981
G Flt1 FMS-related tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:2289965
G Fosl1 FOS like 1, AP-1 transcription factor subunit JBrowse link 1 220,826,560 220,835,066 RGD:2293756
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:2306227
RGD:11554173
G Hoxb13 homeo box B13 JBrowse link 10 84,031,955 84,034,228 RGD:2314726
G Klk10 kallikrein related-peptidase 10 JBrowse link 1 99,718,275 99,722,743 RGD:2314849
G Ldhb lactate dehydrogenase B JBrowse link 4 176,701,980 176,719,999 RGD:11554173
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:2290392
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:2290436
G Notch4 notch receptor 4 JBrowse link 20 4,329,794 4,353,868 RGD:2299156
G Pak2 p21 (RAC1) activated kinase 2 JBrowse link 11 72,829,407 72,865,815 RGD:7775026
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:2289659
G Prkca protein kinase C, alpha JBrowse link 10 96,186,509 96,585,168 RGD:2292458
G Ptges prostaglandin E synthase JBrowse link 3 9,727,408 9,738,752 RGD:2300083
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:2300203
RGD:2300199
G Ptk2 protein tyrosine kinase 2 JBrowse link 7 114,436,419 114,611,317 RGD:2292561
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:2299890
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:2298754
G Slc2a1 solute carrier family 2 member 1 JBrowse link 5 138,154,677 138,182,897 RGD:11554173
G Socs1 suppressor of cytokine signaling 1 JBrowse link 10 4,956,795 4,958,472 RGD:2298909
G Socs2 suppressor of cytokine signaling 2 JBrowse link 7 36,495,496 36,500,878 RGD:2298909
G Socs3 suppressor of cytokine signaling 3 JBrowse link 10 106,973,863 106,976,969 RGD:2298909
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:2315078
G St14 suppression of tumorigenicity 14 JBrowse link 8 32,240,113 32,280,813 RGD:2315089
G Stat5a signal transducer and activator of transcription 5A JBrowse link 10 88,764,732 88,789,060 RGD:2291932
RGD:11554173
RGD:2291930
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:2291992
G Tff1 trefoil factor 1 JBrowse link 20 9,892,124 9,895,984 RGD:2292005
G Timp2 TIMP metallopeptidase inhibitor 2 JBrowse link 10 107,338,465 107,386,072 RGD:2290436
G Timp4 TIMP metallopeptidase inhibitor 4 JBrowse link 4 147,156,948 147,163,467 RGD:2290436
G Top2a DNA topoisomerase II alpha JBrowse link 10 86,901,467 86,930,947 RGD:2315133
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:2289931
G Tymp thymidine phosphorylase JBrowse link 7 130,342,481 130,347,845 RGD:2293726
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:2315458
in situ carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ace angiotensin I converting enzyme JBrowse link 10 94,170,766 94,213,831 RGD:2325208
G Agr2 anterior gradient 2, protein disulphide isomerase family member JBrowse link 6 55,465,782 55,487,087 RGD:2325658
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:1643333
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:2317522
G Alpl alkaline phosphatase, biomineralization associated JBrowse link 5 156,086,496 156,141,513 RGD:2315616
G Angpt1 angiopoietin 1 JBrowse link 7 81,338,327 81,592,459 RGD:1626167
G Casp1 caspase 1 JBrowse link 8 2,605,743 2,614,637 RGD:2298754
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:2296040
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:2296048
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:2289836
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:2290024
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:2290024
G Igf2r insulin-like growth factor 2 receptor JBrowse link 1 48,176,095 48,264,482 RGD:2311631
G Igfbp6 insulin-like growth factor binding protein 6 JBrowse link 7 143,749,385 143,754,018 RGD:2301712
G Mki67 marker of proliferation Ki-67 JBrowse link 1 207,993,895 208,020,454 RGD:2317703
G Pdgfra platelet derived growth factor receptor alpha JBrowse link 14 35,527,926 35,581,130 RGD:2292154
G Pdpn podoplanin JBrowse link 5 161,947,137 161,981,441 RGD:2292235
G Pou5f1 POU class 5 homeobox 1 JBrowse link 20 3,747,231 3,751,994 RGD:2292428
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:2289828
G Ptges prostaglandin E synthase JBrowse link 3 9,727,408 9,738,752 RGD:2300088
RGD:2300087
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:2317187
RGD:11554173
RGD:2317186
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:2299891
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:2314696
G Runx3 runt-related transcription factor 3 JBrowse link 5 153,507,093 153,531,137 RGD:2324958
G Sfn stratifin JBrowse link 5 151,823,422 151,824,937 RGD:2299936
G Sfrp1 secreted frizzled-related protein 1 JBrowse link 16 73,372,007 73,410,777 RGD:2301712
G Xrcc1 X-ray repair cross complementing 1 JBrowse link 1 81,412,635 81,441,680 RGD:10045659
G Zfp354a zinc finger protein 354A JBrowse link 10 36,586,495 36,600,172 RGD:2291889
Leukoplakia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cttn cortactin JBrowse link 1
1
217,602,698
215,255,385
217,638,196
215,290,882
RGD:11554173
mammary Paget's disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 10 86,367,596 86,391,728 RGD:2289933
oral mucosa leukoplakia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:8547871
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:8662371
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 1 80,293,574 80,307,334 RGD:8552678
G Nat2 N-acetyltransferase 2 JBrowse link 16 23,960,709 23,991,570 RGD:8552678
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:11554173
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:8547855
RGD:8547871
G Xrcc1 X-ray repair cross complementing 1 JBrowse link 1 81,412,635 81,441,680 RGD:8552678
Photosensitive Trichothiodystrophy 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 1 80,293,574 80,307,334 RGD:7240710
RGD:8554872
G Gtf2h5 general transcription factor IIH subunit 5 JBrowse link 1 46,978,345 46,985,032 RGD:7246919
RGD:8554872
G Mplkip M-phase specific PLK1 interacting protein JBrowse link 17 49,955,060 49,990,982 RGD:8554872
prostate carcinoma in situ term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Amacr alpha-methylacyl-CoA racemase JBrowse link 2 60,949,276 60,961,342 RGD:2315630
G Ang angiogenin JBrowse link 15 28,022,926 28,028,636 RGD:2325697
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 JBrowse link 15 27,849,943 27,852,083 RGD:2315666
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:11554173
G Areg amphiregulin JBrowse link 14 18,521,921 18,531,179 RGD:2292659
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:2293869
G Aurka aurora kinase A JBrowse link 3 170,364,177 170,380,278 RGD:2293883
RGD:2293877
G Aurkb aurora kinase B JBrowse link 10 55,625,860 55,632,399 RGD:2293877
G Btg2 BTG anti-proliferation factor 2 JBrowse link 13 50,913,185 50,916,944 RGD:2289070
G Carm1 coactivator-associated arginine methyltransferase 1 JBrowse link 8 22,577,723 22,622,555 RGD:2293206
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:2289283
G Ccne1 cyclin E1 JBrowse link 1 94,485,830 94,495,112 RGD:2289283
G Cdh1 cadherin 1 JBrowse link 19 38,768,467 38,838,395 RGD:11554173
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:2299085
RGD:11554173
G Creb3l4 cAMP responsive element binding protein 3-like 4 JBrowse link 2 189,596,657 189,602,243 RGD:13504714
G Csf1r colony stimulating factor 1 receptor JBrowse link 18 56,414,493 56,458,300 RGD:2293712
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:7257711
G Dnmt1 DNA methyltransferase 1 JBrowse link 8 21,922,515 21,968,495 RGD:11554173
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:8553211
RGD:11554173
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:8553211
RGD:11554173
G Fgf6 fibroblast growth factor 6 JBrowse link 4 159,563,798 159,572,333 RGD:2301089
G Fgf8 fibroblast growth factor 8 JBrowse link 1 265,492,949 265,498,965 RGD:2301097
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:2298702
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:2301192
G Flt1 FMS-related tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:2301255
G Fzd4 frizzled class receptor 4 JBrowse link 1 153,589,471 153,598,376 RGD:2298702
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:10401940
RGD:11554173
G Hdac1 histone deacetylase 1 JBrowse link 5 147,716,664 147,743,723 RGD:2306219
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:2306713
G Kras KRAS proto-oncogene, GTPase JBrowse link 4 179,482,562 179,515,483 RGD:2314913
G Lef1 lymphoid enhancer binding factor 1 JBrowse link 2 236,232,115 236,345,061 RGD:11531513
G Lrp1 LDL receptor related protein 1 JBrowse link 7 70,846,313 70,927,028 RGD:1625030
G Map2k4 mitogen activated protein kinase kinase 4 JBrowse link 10 52,196,121 52,301,887 RGD:2293334
G Map2k6 mitogen-activated protein kinase kinase 6 JBrowse link 10 98,707,160 98,823,054 RGD:2293334
G Map2k7 mitogen activated protein kinase kinase 7 JBrowse link 12 2,546,278 2,555,310 RGD:2293334
G Mt2A metallothionein 2A JBrowse link 19 11,307,966 11,308,740 RGD:11554173
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:10059615
G Phb prohibitin JBrowse link 10 83,476,107 83,488,878 RGD:2292382
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase JBrowse link 20 8,165,423 8,169,557 RGD:11554173
G Prss8 serine protease 8 JBrowse link 1 199,372,519 199,377,035 RGD:2292484
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:2292497
RGD:11554173
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:2300123
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:2298767
RGD:2298769
G Rxra retinoid X receptor alpha JBrowse link 3 6,272,560 6,295,354 RGD:1643115
G Slc30a4 solute carrier family 30 member 4 JBrowse link 3 114,805,919 114,828,154 RGD:2299948
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:2300005
G St14 suppression of tumorigenicity 14 JBrowse link 8 32,240,113 32,280,813 RGD:2315088
G Stk11 serine/threonine kinase 11 JBrowse link 7 12,440,751 12,457,513 RGD:2291943
G Timp4 TIMP metallopeptidase inhibitor 4 JBrowse link 4 147,156,948 147,163,467 RGD:2290433
G Top2b DNA topoisomerase II beta JBrowse link 15 10,262,972 10,319,741 RGD:11554173
G Tp63 tumor protein p63 JBrowse link 11 78,234,853 78,456,559 RGD:2315434
RGD:11554173
RGD:2315433
xeroderma pigmentosum term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddb1 damage-specific DNA binding protein 1 JBrowse link 1 226,657,561 226,683,356 RGD:7246919
G Ddb2 damage specific DNA binding protein 2 JBrowse link 3 80,030,437 80,052,984 RGD:1601050
RGD:8554872
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:8554872
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 1 80,293,574 80,307,334 RGD:1601068
RGD:8554872
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit JBrowse link 18 25,037,668 25,068,380 RGD:1598912
RGD:8554872
RGD:7246919
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit JBrowse link 10 2,010,140 2,037,953 RGD:1601093
RGD:8554872
RGD:7246919
G Ercc5 ERCC excision repair 5, endonuclease JBrowse link 9 50,928,847 50,970,962 RGD:7246919
RGD:8554872
G Gtpbp2 GTP binding protein 2 JBrowse link 9 17,198,957 17,208,456 RGD:8554872
G Klc3 kinesin light chain 3 JBrowse link 1 80,306,074 80,315,886 RGD:8554872
G Polh DNA polymerase eta JBrowse link 9 17,163,354 17,198,006 RGD:11554173
RGD:8554872
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:13592920
G Tmem43 transmembrane protein 43 JBrowse link 4 123,118,468 123,133,610 RGD:8554872
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1331525
G Xpa XPA, DNA damage recognition and repair factor JBrowse link 5 61,749,767 61,793,641 RGD:1331525
RGD:8554872
RGD:11554173
RGD:7246919
RGD:1599876
G Xpc XPC complex subunit, DNA damage recognition and repair factor JBrowse link 4 123,134,457 123,161,985 RGD:1599878
RGD:8554872
RGD:11554173
RGD:7246919
xeroderma pigmentosum group A term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Xpa XPA, DNA damage recognition and repair factor JBrowse link 5 61,749,767 61,793,641 RGD:8554872
RGD:7240710
G Xpc XPC complex subunit, DNA damage recognition and repair factor JBrowse link 4 123,134,457 123,161,985 RGD:8554872
xeroderma pigmentosum group B term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit JBrowse link 18 25,037,668 25,068,380 RGD:7240710
RGD:8554872
xeroderma pigmentosum group C term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tmem43 transmembrane protein 43 JBrowse link 4 123,118,468 123,133,610 RGD:8554872
G Xpc XPC complex subunit, DNA damage recognition and repair factor JBrowse link 4 123,134,457 123,161,985 RGD:7240710
RGD:8554872
xeroderma pigmentosum group D term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 1 80,293,574 80,307,334 RGD:7240710
RGD:8554872
xeroderma pigmentosum group E term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddb2 damage specific DNA binding protein 2 JBrowse link 3 80,030,437 80,052,984 RGD:7240710
RGD:8554872
RGD:11554173
xeroderma pigmentosum group F term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit JBrowse link 10 2,010,140 2,037,953 RGD:7240710
RGD:8554872
xeroderma pigmentosum group G term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc5 ERCC excision repair 5, endonuclease JBrowse link 9 50,928,847 50,970,962 RGD:7240710
RGD:8554872
xeroderma pigmentosum variant type term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Polh DNA polymerase eta JBrowse link 9 17,163,354 17,198,006 RGD:7240710
RGD:8554872
XFE progeroid syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:13592920
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit JBrowse link 10 2,010,140 2,037,953 RGD:7240710
RGD:8554872

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14823
    disease of cellular proliferation 5574
      pre-malignant neoplasm 278
        Aberrant Crypt Foci 9
        Erythroplasia 0
        Leukoplakia + 8
        Lymphomatoid Granulomatosis 0
        Preleukemias 0
        Uterine Cervical Dysplasia + 0
        actinic keratosis + 3
        conjunctival intraepithelial neoplasm 0
        corneal intraepithelial neoplasm 0
        in situ carcinoma + 140
        xeroderma pigmentosum + 18
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.