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ONTOLOGY REPORT - ANNOTATIONS


Term:ductal carcinoma in situ
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Accession:DOID:0060074 term browser browse the term
Definition:A noninvasive (noninfiltrating) carcinoma of the breast characterized by a proliferation of malignant epithelial cells confined to the mammary ducts or lobules, without light-microscopy evidence of invasion through the basement membrane into the surrounding stroma.
Synonyms:exact_synonym: Atypical Ductal Hyperplasia;   Atypical Ductal Hyperplasias;   Carcinoma, Intraductal, Noninfiltrating;   DCIS;   Intraductal Carcinoma;   Intraductal Carcinomas;   Noninfiltrating Intraductal Carcinomas
 primary_id: MESH:D002285;   RDO:0005120
For additional species annotation, visit the Alliance of Genome Resources.


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ductal carcinoma in situ term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:10053629
G Ang angiogenin JBrowse link 15 28,022,926 28,028,636 RGD:2325702
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:7421537
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:1643341
G Areg amphiregulin JBrowse link 14 18,521,921 18,531,179 RGD:2292664
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:2289659
G Birc5 baculoviral IAP repeat-containing 5 JBrowse link 10 106,856,097 106,864,419 RGD:2293106
G Bnip3 BCL2 interacting protein 3 JBrowse link 1 211,248,098 211,265,282 RGD:7483575
G Brca2 BRCA2, DNA repair associated JBrowse link 12 503,660 544,754 RGD:2289048
G Ca9 carbonic anhydrase 9 JBrowse link 5 59,008,277 59,015,535 RGD:11554173
G Casp6 caspase 6 JBrowse link 2 235,341,326 235,353,715 RGD:2301339
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:2289132
G Ccnd2 cyclin D2 JBrowse link 4 159,674,885 159,697,207 RGD:2289156
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:2289659
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 10 86,367,596 86,391,728 RGD:2289981
RGD:2289931
G Erbb3 erb-b2 receptor tyrosine kinase 3 JBrowse link 7 2,989,202 3,010,610 RGD:2289952
G Erbb4 erb-b2 receptor tyrosine kinase 4 JBrowse link 9 75,021,790 76,178,936 RGD:2289981
G Flt1 Fms related receptor tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:2289965
G Fosl1 FOS like 1, AP-1 transcription factor subunit JBrowse link 1 220,826,560 220,835,066 RGD:2293756
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:2306227
RGD:11554173
G Hoxb13 homeo box B13 JBrowse link 10 84,031,955 84,034,228 RGD:2314726
G Klk10 kallikrein related-peptidase 10 JBrowse link 1 99,718,275 99,722,743 RGD:2314849
G Ldhb lactate dehydrogenase B JBrowse link 4 176,701,980 176,719,999 RGD:11554173
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:2290392
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:2290436
G Notch4 notch receptor 4 JBrowse link 20 4,329,794 4,353,868 RGD:2299156
G Pak2 p21 (RAC1) activated kinase 2 JBrowse link 11 72,829,407 72,865,815 RGD:7775026
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:2289659
G Prkca protein kinase C, alpha JBrowse link 10 96,186,509 96,585,168 RGD:2292458
G Ptges prostaglandin E synthase JBrowse link 3 9,727,408 9,738,752 RGD:2300083
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:2300203
RGD:2300199
G Ptk2 protein tyrosine kinase 2 JBrowse link 7 114,436,419 114,611,317 RGD:2292561
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:2299890
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:2298754
G Slc2a1 solute carrier family 2 member 1 JBrowse link 5 138,154,677 138,182,897 RGD:11554173
G Socs1 suppressor of cytokine signaling 1 JBrowse link 10 4,956,795 4,958,472 RGD:2298909
G Socs2 suppressor of cytokine signaling 2 JBrowse link 7 36,495,496 36,500,878 RGD:2298909
G Socs3 suppressor of cytokine signaling 3 JBrowse link 10 106,973,863 106,976,969 RGD:2298909
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:2315078
G St14 suppression of tumorigenicity 14 JBrowse link 8 32,240,113 32,280,813 RGD:2315089
G Stat5a signal transducer and activator of transcription 5A JBrowse link 10 88,764,732 88,789,060 RGD:2291932
RGD:11554173
RGD:2291930
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:2291992
G Tff1 trefoil factor 1 JBrowse link 20 9,892,124 9,895,984 RGD:2292005
G Timp2 TIMP metallopeptidase inhibitor 2 JBrowse link 10 107,338,465 107,386,072 RGD:2290436
G Timp4 TIMP metallopeptidase inhibitor 4 JBrowse link 4 147,156,948 147,163,467 RGD:2290436
G Top2a DNA topoisomerase II alpha JBrowse link 10 86,901,467 86,930,947 RGD:2315133
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:2289931
G Tymp thymidine phosphorylase JBrowse link 7 130,342,481 130,347,845 RGD:2293726
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:2315458
mammary Paget's disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 10 86,367,596 86,391,728 RGD:2289933

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15610
    disease of cellular proliferation 5827
      Neoplasms by Histologic Type 3641
        Glandular and Epithelial Neoplasms 2111
          Neoplasms, Ductal, Lobular, and Medullary 254
            ductal carcinoma in situ 49
              comedo carcinoma 0
              mammary Paget's disease 1
Path 2
Term Annotations click to browse term
  disease 15610
    disease of anatomical entity 14968
      nervous system disease 10400
        sensory system disease 4770
          skin disease 2495
            breast disease 1170
              Breast Neoplasms 1161
                breast cancer 516
                  breast carcinoma 249
                    breast carcinoma in situ 50
                      ductal carcinoma in situ 49
                        comedo carcinoma 0
                        mammary Paget's disease 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.