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ONTOLOGY REPORT - ANNOTATIONS


Term:integumentary system cancer
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Accession:DOID:0060122 term browser browse the term
Definition:An organ system cancer that is located_in the skin, hair and nails. (DO)
For additional species annotation, visit the Alliance of Genome Resources.


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basal cell carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asip agouti signaling protein JBrowse link 3 150,492,010 150,579,870 RGD:11554173
G Bap1 Brca1 associated protein 1 JBrowse link 16 7,336,685 7,345,511 RGD:9586038
RGD:11554173
G Ccnh cyclin H JBrowse link 2 13,593,100 13,613,910 RGD:8554872
G Clptm1l CLPTM1-like JBrowse link 1 32,281,207 32,297,196 RGD:11554173
G Crnkl1 crooked neck pre-mRNA splicing factor 1 JBrowse link 6 18,349,226 18,351,540 RGD:9850250
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 JBrowse link 9 67,699,397 67,706,068 RGD:7411686
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 10 86,367,596 86,391,728 RGD:11554173
G Fbxw7 F-box and WD repeat domain containing 7 JBrowse link 2 184,230,191 184,309,805 RGD:11554173
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:11554173
G Hhip Hedgehog-interacting protein JBrowse link 19 31,525,134 31,614,487 RGD:11552592
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:11554173
G Krt17 keratin 17 JBrowse link 10 88,158,993 88,163,712 RGD:11554173
G Krt5 keratin 5 JBrowse link 7 143,320,142 143,324,536 RGD:11554173
G Lats1 large tumor suppressor kinase 1 JBrowse link 1 1,784,078 1,817,310 RGD:11554173
G Mc1r melanocortin 1 receptor JBrowse link 19 56,215,420 56,219,987 RGD:11554173
G Mycn MYCN proto-oncogene, bHLH transcription factor JBrowse link 6 38,222,554 38,228,419 RGD:11554173
G Oca2 OCA2 melanosomal transmembrane protein JBrowse link 1 114,661,970 114,987,433 RGD:9491840
RGD:9491841
G Ogg1 8-oxoguanine DNA glycosylase JBrowse link 4 145,282,828 145,289,367 RGD:8657137
RGD:8657158
G Palb2 partner and localizer of BRCA2 JBrowse link 1 192,064,586 192,088,547 RGD:8554872
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha JBrowse link 2 118,831,350 118,861,456 RGD:11554173
G Ppp6c protein phosphatase 6, catalytic subunit JBrowse link 3 23,478,123 23,510,959 RGD:11554173
G Ptch1 patched 1 JBrowse link 17 1,032,242 1,085,885 RGD:704355
RGD:8554872
RGD:12801453
RGD:11554173
RGD:7240710
G Ptch2 patched 2 JBrowse link 5 135,962,252 135,983,816 RGD:8554872
RGD:7240710
G Ptpn14 protein tyrosine phosphatase, non-receptor type 14 JBrowse link 13 108,689,916 108,841,593 RGD:11554173
G Rasa1 RAS p21 protein activator 1 JBrowse link 2 13,617,021 13,696,531 RGD:737716
RGD:8554872
RGD:7240710
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:11554173
G Rpe65 RPE65, retinoid isomerohydrolase JBrowse link 2 266,141,581 266,169,197 RGD:9495923
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:12801452
G Slc45a2 solute carrier family 45, member 2 JBrowse link 2 60,966,671 60,999,398 RGD:11554173
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:704355
RGD:7240710
RGD:8554872
RGD:12801453
RGD:11554173
G Stk19 serine/threonine kinase 19 JBrowse link 20 4,317,440 4,517,128 RGD:11554173
G Sufu SUFU negative regulator of hedgehog signaling JBrowse link 1 266,143,766 266,241,742 RGD:11554173
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:11554173
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:8547844
RGD:8554872
RGD:11554173
RGD:7240710
RGD:8547848
G Tyr tyrosinase JBrowse link 1 151,012,598 151,106,802 RGD:11554173
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:8158063
RGD:8158076
G Xpa XPA, DNA damage recognition and repair factor JBrowse link 5 61,749,767 61,793,641 RGD:11554173
G Xrcc3 X-ray repair cross complementing 3 JBrowse link 6 136,366,917 136,380,751 RGD:11554173
G Xrcc5 X-ray repair cross complementing 5 JBrowse link 9 79,659,275 79,748,050 RGD:8698657
G Xrcc6 X-ray repair cross complementing 6 JBrowse link 7 123,259,881 123,280,613 RGD:8698657
Cutaneous Malignant Melanoma, Susceptibility To, 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:8554872
G Stk11 serine/threonine kinase 11 JBrowse link 7 12,440,751 12,457,513 RGD:8554872
Cutaneous Malignant Melanoma, Susceptibility To, 10 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pot1 protection of telomeres 1 JBrowse link 4 51,888,632 51,946,764 RGD:8554872
RGD:7240710
Cutaneous Malignant Melanoma, Susceptibility To, 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:7240710
RGD:8554872
Cutaneous Malignant Melanoma, Susceptibility To, 3 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdk4 cyclin-dependent kinase 4 JBrowse link 7 70,345,971 70,352,689 RGD:7240710
RGD:8554872
G Tspan31 tetraspanin 31 JBrowse link 7 70,352,679 70,355,555 RGD:8554872
Cutaneous Malignant Melanoma, Susceptibility To, 5 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mc1r melanocortin 1 receptor JBrowse link 19 56,215,420 56,219,987 RGD:7240710
RGD:8554872
Cutaneous Malignant Melanoma, Susceptibility To, 6 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Klc1 kinesin light chain 1 JBrowse link 6 136,330,151 136,373,716 RGD:8554872
G Xrcc3 X-ray repair cross complementing 3 JBrowse link 6 136,366,917 136,380,751 RGD:8554872
RGD:7240710
Cutaneous Malignant Melanoma, Susceptibility To, 8 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mitf melanocyte inducing transcription factor JBrowse link 4 130,172,484 130,425,496 RGD:7240710
RGD:8554872
RGD:11554173
G Tyr tyrosinase JBrowse link 1 151,012,598 151,106,802 RGD:8554872
Cutaneous Malignant Melanoma, Susceptibility To, 9 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:8554872
RGD:7240710
familial melanoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdk4 cyclin-dependent kinase 4 JBrowse link 7 70,345,971 70,352,689 RGD:8554872
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:8554872
Ferguson-Smith tumor term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tgfbr1 transforming growth factor, beta receptor 1 JBrowse link 5 63,056,071 63,119,635 RGD:7240710
RGD:8554872
RGD:11554173
Merkel cell carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:11554173
G Sdhd succinate dehydrogenase complex subunit D JBrowse link 8 55,028,125 55,037,604 RGD:8554872
nevoid basal cell carcinoma syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gli1 GLI family zinc finger 1 JBrowse link 7 70,620,794 70,633,171 RGD:12801443
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:11554173
G Ptch1 patched 1 JBrowse link 17 1,032,242 1,085,885 RGD:7240710
RGD:8554872
RGD:13207424
RGD:13207421
RGD:12801443
RGD:12801422
RGD:12798568
RGD:11554173
G Ptch2 patched 2 JBrowse link 5 135,962,252 135,983,816 RGD:8554872
RGD:7240710
G Pth parathyroid hormone JBrowse link 1 178,215,829 178,218,761 RGD:11554173
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:12802345
G Smo smoothened, frizzled class receptor JBrowse link 4 57,019,941 57,041,779 RGD:12801443
G Sufu SUFU negative regulator of hedgehog signaling JBrowse link 1 266,143,766 266,241,742 RGD:7240710
RGD:8554872
PALMOPLANTAR CARCINOMA, MULTIPLE SELF-HEALING term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nlrp1a NLR family, pyrin domain containing 1A JBrowse link 10 57,692,474 57,747,608 RGD:7240710
RGD:8554872
skin cancer term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa7 annexin A7 JBrowse link 15 4,254,470 4,281,296 RGD:2292654
G Chuk conserved helix-loop-helix ubiquitous kinase JBrowse link 1 263,848,829 263,884,354 RGD:13504775
G Crkl CRK like proto-oncogene, adaptor protein JBrowse link 11 87,338,606 87,356,644 RGD:7488899
G Snai1 snail family transcriptional repressor 1 JBrowse link 3 164,274,710 164,279,199 RGD:13592920
G Srsf6 serine and arginine rich splicing factor 6 JBrowse link 3 159,305,345 159,310,668 RGD:11039481
skin melanoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:8548874
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:8554872
G Bap1 Brca1 associated protein 1 JBrowse link 16 7,336,685 7,345,511 RGD:11554173
G Braf B-Raf proto-oncogene, serine/threonine kinase JBrowse link 4 67,389,331 67,520,549 RGD:8554872
G Brca2 BRCA2, DNA repair associated JBrowse link 12 503,660 544,754 RGD:11344896
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:8547772
G Cdk4 cyclin-dependent kinase 4 JBrowse link 7 70,345,971 70,352,689 RGD:13592920
RGD:8554872
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:11554173
RGD:8554872
G Chaf1b chromatin assembly factor 1 subunit B JBrowse link 11 34,101,248 34,121,371 RGD:9587476
G Cnr1 cannabinoid receptor 1 JBrowse link 5 49,307,584 49,333,064 RGD:11554173
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:8554872
G Dnmt3b DNA methyltransferase 3 beta JBrowse link 3 149,131,541 149,170,061 RGD:9589074
G Erbb4 erb-b2 receptor tyrosine kinase 4 JBrowse link 9 75,021,790 76,178,936 RGD:8554872
G Fanca FA complementation group A JBrowse link 19 56,067,548 56,126,075 RGD:11344896
G Fancd2 FA complementation group D2 JBrowse link 4 145,489,869 145,551,479 RGD:11046262
G Gna11 G protein subunit alpha 11 JBrowse link 7 11,033,400 11,047,284 RGD:8554872
G Gnaq G protein subunit alpha q JBrowse link 1 233,382,778 233,622,584 RGD:8554872
G Grm1 glutamate metabotropic receptor 1 JBrowse link 1 4,753,141 5,165,859 RGD:13592920
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:12792221
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:12792221
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:8695922
G Hras HRas proto-oncogene, GTPase JBrowse link 1 214,178,404 214,181,841 RGD:8554872
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:8547698
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 14 35,072,131 35,149,638 RGD:8554872
G Lrrc56 leucine rich repeat containing 56 JBrowse link 1 214,182,232 214,197,184 RGD:8554872
G Map2k1 mitogen activated protein kinase kinase 1 JBrowse link 8 69,134,218 69,722,573 RGD:8554872
G Map2k2 mitogen activated protein kinase kinase 2 JBrowse link 7 11,458,971 11,478,520 RGD:8554872
G Mc1r melanocortin 1 receptor JBrowse link 19 56,215,420 56,219,987 RGD:13592920
G Mitf melanocyte inducing transcription factor JBrowse link 4 130,172,484 130,425,496 RGD:11554173
G Mmp1 matrix metallopeptidase 1 JBrowse link 8 5,703,206 5,723,593 RGD:8549726
RGD:8549727
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:8657055
RGD:13204786
RGD:8657075
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:8547886
RGD:13204786
G Nras NRAS proto-oncogene, GTPase JBrowse link 2 205,553,119 205,563,716 RGD:8554872
G Oca2 OCA2 melanosomal transmembrane protein JBrowse link 1 114,661,970 114,987,433 RGD:9491818
RGD:9491831
RGD:9491829
G Pdgfra platelet derived growth factor receptor alpha JBrowse link 14 35,527,926 35,581,130 RGD:8554872
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha JBrowse link 2 118,831,350 118,861,456 RGD:8554872
G Pot1 protection of telomeres 1 JBrowse link 4 51,888,632 51,946,764 RGD:13592920
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:8554872
G Rac1 Rac family small GTPase 1 JBrowse link 12 13,090,316 13,111,841 RGD:8554872
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link 4 147,532,040 147,592,769 RGD:8554872
G Snapc5 small nuclear RNA activating complex, polypeptide 5 JBrowse link 8 69,127,708 69,131,539 RGD:8554872
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:8694297
G Stk11 serine/threonine kinase 11 JBrowse link 7 12,440,751 12,457,513 RGD:8554872
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:13592920
G Tyr tyrosinase JBrowse link 1 151,012,598 151,106,802 RGD:8694390
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:8157629
G Xrcc3 X-ray repair cross complementing 3 JBrowse link 6 136,366,917 136,380,751 RGD:13592920
skin squamous cell carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddx5 DEAD-box helicase 5 JBrowse link 10 94,979,759 94,988,461 RGD:9850272
G Fyn FYN proto-oncogene, Src family tyrosine kinase JBrowse link 20 44,436,354 44,630,316 RGD:13592920

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14759
    disease of anatomical entity 13978
      integumentary system disease 2240
        integumentary system cancer 94
          skin cancer + 94
Path 2
Term Annotations click to browse term
  disease 14759
    disease of cellular proliferation 5566
      cancer 3957
        organ system cancer 3768
          integumentary system cancer 94
            skin cancer + 94
paths to the root