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ONTOLOGY REPORT - ANNOTATIONS


Term:drug allergy
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Accession:DOID:0060500 term browser browse the term
Definition:Immunologically mediated adverse reactions to medicinal substances used legally or illegally.
Synonyms:exact_synonym: Drug Allergies;   Drug Hypersensitivities;   Drug Hypersensitivity
 primary_id: MESH:D004342;   RDO:0001147
For additional species annotation, visit the Alliance of Genome Resources.


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drug allergy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:11554173
G Ace angiotensin I converting enzyme JBrowse link 10 94,170,766 94,213,831 RGD:11554173
G Adora1 adenosine A1 receptor JBrowse link 13 51,042,111 51,076,913 RGD:11554173
G Adora2a adenosine A2a receptor JBrowse link 20 14,265,251 14,282,873 RGD:11554173
G Ccl11 C-C motif chemokine ligand 11 JBrowse link 10 69,434,965 69,439,566 RGD:11554173
G Ccl24 C-C motif chemokine ligand 24 JBrowse link 12 24,131,529 24,152,626 RGD:11554173
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 JBrowse link 1 257,676,172 258,004,428 RGD:11554173
G Cysltr1 cysteinyl leukotriene receptor 1 JBrowse link X 77,671,028 77,700,491 RGD:11554173
G Cysltr2 cysteinyl leukotriene receptor 2 JBrowse link 15 54,903,290 54,941,742 RGD:11554173
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:11554173
G Fcer1a Fc fragment of IgE receptor Ia JBrowse link 13 91,727,253 91,737,106 RGD:11554173
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link 13 89,601,894 89,606,326 RGD:11554173
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:5491000
RGD:11554173
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:5490995
RGD:11554173
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:5491000
G Gzmb granzyme B JBrowse link 15 35,413,862 35,417,293 RGD:11554173
G Hnmt histamine N-methyltransferase JBrowse link 3 905,111 937,038 RGD:11554173
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:11554173
G Hspa1l heat shock protein family A (Hsp70) member 1 like JBrowse link 20 4,879,998 4,965,191 RGD:11554173
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:11554173
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:11554173
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:8662975
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:11554173
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:11554173
G Ltc4s leukotriene C4 synthase JBrowse link 10 35,736,486 35,743,088 RGD:11554173
G Mln motilin JBrowse link 20 6,567,092 6,571,791 RGD:11554173
G Ms4a2 membrane spanning 4-domains A2 JBrowse link 1 227,957,363 227,965,312 RGD:11554173
G Nat2 N-acetyltransferase 2 JBrowse link 16 23,960,709 23,991,570 RGD:11554173
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 10 45,884,324 45,918,290 RGD:11554173
G Postn periostin JBrowse link 2 143,656,820 143,688,087 RGD:11554173
G Ptger3 prostaglandin E receptor 3 JBrowse link 2 263,895,093 263,979,682 RGD:11554173
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:11554173
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:11554173
G Tac1 tachykinin, precursor 1 JBrowse link 4 33,638,853 33,646,819 RGD:11554173
G Tbxas1 thromboxane A synthase 1 JBrowse link 4 66,624,181 66,846,745 RGD:11554173
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:11554173
G Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b JBrowse link 15 51,433,853 51,464,215 RGD:11554173
Aspirin-Induced Asthma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacng6 calcium voltage-gated channel auxiliary subunit gamma 6 JBrowse link 1 64,307,684 64,322,124 RGD:13524562
G Ccr3 C-C motif chemokine receptor 3 JBrowse link 8 133,026,539 133,040,999 RGD:4145619
RGD:11554173
G Cysltr1 cysteinyl leukotriene receptor 1 JBrowse link X 77,671,028 77,700,491 RGD:11554173
G Cysltr2 cysteinyl leukotriene receptor 2 JBrowse link 15 54,903,290 54,941,742 RGD:5144000
RGD:11554173
G Fancc FA complementation group C JBrowse link 17 826,512 955,703 RGD:11045795
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:11528633
G Ltc4s leukotriene C4 synthase JBrowse link 10 35,736,486 35,743,088 RGD:11554173
G Ms4a2 membrane spanning 4-domains A2 JBrowse link 1 227,957,363 227,965,312 RGD:11554173
G Postn periostin JBrowse link 2 143,656,820 143,688,087 RGD:11554173
G Ptgdr2 prostaglandin D2 receptor 2 JBrowse link 1 226,976,455 226,995,641 RGD:11554173
G Ptger2 prostaglandin E receptor 2 JBrowse link 15 19,336,029 19,349,759 RGD:8554872
RGD:11554173
G Ptgir prostaglandin I2 receptor JBrowse link 1 78,833,449 78,835,832 RGD:11554173
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:5143936
RGD:11554173
G RT1-Ba RT1 class II, locus Ba JBrowse link 20 4,066,133 4,070,726 RGD:11074090
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:11074090
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:11074090
G Tap2 transporter 2, ATP binding cassette subfamily B member JBrowse link 20 3,995,544 4,009,587 RGD:5147839
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:8554872
RGD:11554173
G Tbxa2r thromboxane A2 receptor JBrowse link 7 11,253,153 11,259,233 RGD:11059537
RGD:11554173
Asthma, Nasal Polyps, and Aspirin Intolerance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox15 arachidonate 15-lipoxygenase JBrowse link 10 56,953,692 56,962,145 RGD:8554872
G Ptger2 prostaglandin E receptor 2 JBrowse link 15 19,336,029 19,349,759 RGD:7240710
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:7240710
RGD:8554872
Drug Eruptions term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:11554173
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:11554173
G Apoc2 apolipoprotein C2 JBrowse link 1 80,589,023 80,593,991 RGD:11554173
G Apoc3 apolipoprotein C3 JBrowse link 8 50,529,318 50,531,498 RGD:11554173
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:8657071
G C4b complement C4B (Chido blood group) JBrowse link 20 4,302,344 4,316,752 RGD:11554173
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:11554173
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 JBrowse link 1 147,713,879 147,814,410 RGD:11352742
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:11554173
G Fcer1a Fc fragment of IgE receptor Ia JBrowse link 13 91,727,253 91,737,106 RGD:11554173
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:11554173
G Il17a interleukin 17A JBrowse link 9 26,841,299 26,844,786 RGD:11554173
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:11554173
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:11554173
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:11554173
G Kng2 kininogen 2 JBrowse link 11 81,509,185 81,516,759 RGD:11554173
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:11554173
G Mthfr methylenetetrahydrofolate reductase JBrowse link 5 164,844,642 164,864,360 RGD:11554173
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:11554173
G RT1-Ba RT1 class II, locus Ba JBrowse link 20 4,066,133 4,070,726 RGD:8547665
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:11554173
G Tac1 tachykinin, precursor 1 JBrowse link 4 33,638,853 33,646,819 RGD:11554173
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:11554173
G Ttr transthyretin JBrowse link 18 15,532,963 15,542,180 RGD:11554173
Drug Hypersensitivity Syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hspa1l heat shock protein family A (Hsp70) member 1 like JBrowse link 20 4,879,998 4,965,191 RGD:8662461
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:11051970
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:11051970
Erythema Nodosum term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:7421527
G Cfb complement factor B JBrowse link 20 4,536,206 4,542,073 RGD:7421527
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:7794848
G Lta lymphotoxin alpha JBrowse link 20 4,851,889 4,854,677 RGD:8548773
G RT1-CE13 RT1 class I, locus CE13 RGD:7364926
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:7364926
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:13217417
Hand-Foot Syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kdr kinase insert domain receptor JBrowse link 14 34,727,677 34,787,127 RGD:8552374
Nakajo Syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Psmb4 proteasome 20S subunit beta 4 JBrowse link 2 196,043,546 196,046,320 RGD:8554872
G Psmb8 proteasome 20S subunit beta 8 JBrowse link 20 3,990,809 3,993,772 RGD:8554872
Poor Metabolism of Thiopurines, 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tpmt thiopurine S-methyltransferase JBrowse link 17 18,029,090 18,047,716 RGD:7240710
RGD:8554872
Poor Metabolism of Thiopurines, 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nudt15 nudix hydrolase 15 JBrowse link 15 55,417,774 55,456,698 RGD:8554872
RGD:7240710
Serum Sickness term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:11554173
Stevens-Johnson syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:11554173
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:11554173
G Celf2 CUGBP, Elav-like family member 2 JBrowse link 17 75,259,269 75,660,154 RGD:11554173
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:8699507
G Cops5 COP9 signalosome subunit 5 JBrowse link 5 8,876,090 8,894,345 RGD:11554173
G Csf3 colony stimulating factor 3 JBrowse link 10 86,616,785 86,619,160 RGD:11554173
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:11554173
G Cul1 cullin 1 JBrowse link 4 77,211,814 77,283,369 RGD:11554173
G Cul4a cullin 4A JBrowse link 16 81,718,784 81,756,653 RGD:11554173
G Derl1 derlin 1 JBrowse link 7 97,737,176 97,759,852 RGD:11554173
G Elmo1 engulfment and cell motility 1 JBrowse link 17 46,352,102 46,888,788 RGD:11554173
G Ep300 E1A binding protein p300 JBrowse link 7 122,818,194 122,889,055 RGD:11554173
G Fbxo6 F-box protein 6 JBrowse link 5 164,956,285 164,962,075 RGD:11554173
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:14700974
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:11554173
G LOC100364500 RT1 class I, locus CE11-like JBrowse link 20 2,704,153 2,707,111 RGD:8554872
RGD:11554173
RGD:7240710
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:11554173
G Nedd4 NEDD4 E3 ubiquitin protein ligase JBrowse link 8 79,323,408 79,408,842 RGD:11554173
G Nfkbiz NFKB inhibitor zeta JBrowse link 11 47,243,342 47,271,487 RGD:13592920
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:11554173
G Nucb1 nucleobindin 1 JBrowse link 1 101,480,160 101,511,029 RGD:11554173
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:11554173
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:11554173
G Psmc5 proteasome 26S subunit, ATPase 5 JBrowse link 10 94,445,877 94,451,811 RGD:11554173
G Ptger3 prostaglandin E receptor 3 JBrowse link 2 263,895,093 263,979,682 RGD:11554173
G Ptgis prostaglandin I2 synthase JBrowse link 3 163,950,746 163,986,129 RGD:11554173
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:11554173
G Rbx1 ring-box 1 JBrowse link 7 122,700,849 122,710,907 RGD:11554173
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:7483570
G RT1-CE13 RT1 class I, locus CE13 RGD:7364874
RGD:7365090
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:7401184
G Vcp valosin-containing protein JBrowse link 5 58,426,548 58,445,953 RGD:11554173
thiopurine S-methyltransferase deficiency term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tpmt thiopurine S-methyltransferase JBrowse link 17 18,029,090 18,047,716 RGD:8554872
RGD:11554173

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15590
    Chemically-Induced Disorders 1165
      Drug-Related Side Effects and Adverse Reactions 565
        drug allergy 105
          Aspirin-Induced Asthma + 20
          D-mannitol allergy 0
          Drug Eruptions + 63
          abacavir allergy 0
          alcuronium bromide allergy 0
          amodiaquine allergy 0
          aspirin allergy 0
          beta-lactam allergy + 0
          carbamazepine allergy 0
          carbapenem allergy 0
          cephalosporin allergy + 0
          chlorhexidine allergy 0
          co-trimoxazole allergy 0
          corticosteroid allergy 0
          cyclophosphamide allergy 0
          diclofenac allergy 0
          disodium cromoglycate allergy 0
          gallamine allergy 0
          isoniazide allergy 0
          ketoprofen photoallergic dermatitis 0
          lidocaine allergy 0
          melphalan allergy 0
          mepivacaine allergy 0
          neomycin sulfate allergic contact dermatitis 0
          oxirane allergy 0
          patent blue V allergy 0
          phenobarbital allergy 0
          phenytoin allergy 0
          phthalyl group allergy 0
          quinidine allergy 0
          ranitidine allergy 0
          rocuronium allergy 0
          sodium aurothiomalate allergy 0
          succinylcholine allergy 0
          sulfamethoxazole allergy 0
          sulfasalazine allergy 0
          sulfonamide allergy 0
          suprofen allergy 0
          thiopental allergy 0
          thiopurine S-methyltransferase deficiency + 2
          trimethoprim allergy 0
          tubocurarine allergy 0
Path 2
Term Annotations click to browse term
  disease 15590
    disease of anatomical entity 14919
      Immune & Inflammatory Diseases 3089
        immune system disease 2517
          hypersensitivity reaction disease 1489
            allergic hypersensitivity disease 554
              drug allergy 105
                Aspirin-Induced Asthma + 20
                D-mannitol allergy 0
                Drug Eruptions + 63
                abacavir allergy 0
                alcuronium bromide allergy 0
                amodiaquine allergy 0
                aspirin allergy 0
                beta-lactam allergy + 0
                carbamazepine allergy 0
                carbapenem allergy 0
                cephalosporin allergy + 0
                chlorhexidine allergy 0
                co-trimoxazole allergy 0
                corticosteroid allergy 0
                cyclophosphamide allergy 0
                diclofenac allergy 0
                disodium cromoglycate allergy 0
                gallamine allergy 0
                isoniazide allergy 0
                ketoprofen photoallergic dermatitis 0
                lidocaine allergy 0
                melphalan allergy 0
                mepivacaine allergy 0
                neomycin sulfate allergic contact dermatitis 0
                oxirane allergy 0
                patent blue V allergy 0
                phenobarbital allergy 0
                phenytoin allergy 0
                phthalyl group allergy 0
                quinidine allergy 0
                ranitidine allergy 0
                rocuronium allergy 0
                sodium aurothiomalate allergy 0
                succinylcholine allergy 0
                sulfamethoxazole allergy 0
                sulfasalazine allergy 0
                sulfonamide allergy 0
                suprofen allergy 0
                thiopental allergy 0
                thiopurine S-methyltransferase deficiency + 2
                trimethoprim allergy 0
                tubocurarine allergy 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.