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ONTOLOGY REPORT - ANNOTATIONS


Term:myeloid neoplasm
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Accession:DOID:0070004 term browser browse the term
Definition:Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE.
Synonyms:exact_synonym: Myeloproliferative Disorder;   Myeloproliferative Disorders;   myeloma
 primary_id: MESH:D009196;   RDO:0004832
For additional species annotation, visit the Alliance of Genome Resources.


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myeloid neoplasm term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ALOX12 arachidonate 12-lipoxygenase, 12S type JBrowse link 17 7,014,038 7,029,602 RGD:9068941
G ATG2B autophagy related 2B JBrowse link 14 96,233,322 96,314,881 RGD:9068941
G BCR BCR activator of RhoGEF and GTPase JBrowse link 22 21,803,806 21,922,123 RGD:9068941
G CBL Cbl proto-oncogene JBrowse link 11 117,973,187 118,076,459 RGD:9068941
G CD36 CD36 molecule JBrowse link 7 86,228,856 86,305,865 RGD:9068941
G CSF1R colony stimulating factor 1 receptor JBrowse link 5 151,483,948 151,543,128 RGD:9068941
G EGR1 early growth response 1 JBrowse link 5 139,975,635 139,979,259 RGD:9068941
G ETV6 ETS variant 6 JBrowse link 12 12,035,107 12,179,537 RGD:9068941
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 7 153,017,590 153,059,726 RGD:9068941
G F3 coagulation factor III, tissue factor JBrowse link 1 95,918,359 95,931,050 RGD:9068941
G FGFR1 fibroblast growth factor receptor 1 JBrowse link 8 34,890,147 34,948,904 RGD:9068941
G FGFR1OP2 FGFR1 oncogene partner 2 JBrowse link 12 61,960,483 61,986,826 RGD:9068941
G FGFR3 fibroblast growth factor receptor 3 JBrowse link 4 1,843,780 1,858,635 RGD:9068941
G FLT3 fms related tyrosine kinase 3 JBrowse link 13 27,627,178 27,694,863 RGD:9068941
G GFI1 growth factor independent 1 transcriptional repressor JBrowse link 1 93,875,880 93,883,558 RGD:9068941
G GFI1B growth factor independent 1B transcriptional repressor JBrowse link 9 132,692,343 132,742,326 RGD:9068941
G GPX1 glutathione peroxidase 1 JBrowse link 3 50,360,736 50,362,274 RGD:9068941
G GSKIP GSK3B interacting protein JBrowse link 14 96,331,789 96,339,378 RGD:9068941
G HSPA5 heat shock protein family A (Hsp70) member 5 JBrowse link 9 124,865,211 124,870,458 RGD:9068941
G INSL6 insulin like 6 JBrowse link 9 5,192,023 5,213,827 RGD:9068941
G IRF4 interferon regulatory factor 4 JBrowse link 6 341,637 360,492 RGD:9068941
G IRF8 interferon regulatory factor 8 JBrowse link 16 85,905,334 85,929,073 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 9 5,006,271 5,156,626 RGD:9068941
G KRAS KRAS proto-oncogene, GTPase JBrowse link 12 63,679,293 63,724,335 RGD:9068941
G MECOM MDS1 and EVI1 complex locus JBrowse link 3 174,154,814 174,731,344 RGD:9068941
G MTHFR methylenetetrahydrofolate reductase JBrowse link 1 11,766,334 11,785,645 RGD:9068941
G NPM1 nucleophosmin 1 JBrowse link 5 173,490,197 173,510,657 RGD:9068941
G NQO1 NAD(P)H quinone dehydrogenase 1 JBrowse link 16 69,472,529 69,489,731 RGD:9068941
G NQO2 N-ribosyldihydronicotinamide:quinone reductase 2 JBrowse link 6 2,928,021 2,947,304 RGD:9068941
G NRAS NRAS proto-oncogene, GTPase JBrowse link 1 122,890,505 122,903,585 RGD:9068941
G RUNX1 RUNX family transcription factor 1 JBrowse link 21 34,526,631 34,788,930 RGD:9068941
G ZMYM2 zinc finger MYM-type containing 2 JBrowse link 13 19,597,963 19,727,913 RGD:9068941
Acute Erythroblastic Leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase JBrowse link 2A 27,306,488 27,332,804 RGD:9068941
G DHODH dihydroorotate dehydrogenase (quinone) JBrowse link 16 71,854,238 71,870,673 RGD:9068941
G UMPS uridine monophosphate synthetase JBrowse link 3 128,731,309 128,745,241 RGD:9068941
Acute Erythroleukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DDX41 DEAD-box helicase 41 JBrowse link 5 179,874,281 179,880,685 RGD:9068941
G ERBB3 erb-b2 receptor tyrosine kinase 3 JBrowse link 12 33,062,681 33,085,426 RGD:9068941
G FLT3 fms related tyrosine kinase 3 JBrowse link 13 27,627,178 27,694,863 RGD:9068941
G GFI1B growth factor independent 1B transcriptional repressor JBrowse link 9 132,692,343 132,742,326 RGD:9068941
G HOXB9 homeobox B9 JBrowse link 17 9,095,438 9,100,755 RGD:9068941
G KMT2A lysine methyltransferase 2A JBrowse link 11 117,203,337 117,294,755 RGD:9068941
G NPM1 nucleophosmin 1 JBrowse link 5 173,490,197 173,510,657 RGD:9068941
G NUP98 nucleoporin 98 JBrowse link 11 3,660,482 3,782,552 RGD:9068941
G RB1 RB transcriptional corepressor 1 JBrowse link 13 48,155,608 48,326,396 RGD:9068941
G TP53 tumor protein p53 JBrowse link 17 7,687,132 7,706,120 RGD:9068941
atypical chronic myeloid leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FGFR1 fibroblast growth factor receptor 1 JBrowse link 8 34,890,147 34,948,904 RGD:9068941
G SETBP1 SET binding protein 1 JBrowse link 18 41,521,063 41,890,262 RGD:9068941
Blast Crisis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AICDA activation induced cytidine deaminase JBrowse link 12 8,903,288 8,913,895 RGD:9068941
G BCR BCR activator of RhoGEF and GTPase JBrowse link 22 21,803,806 21,922,123 RGD:9068941
G ESR2 estrogen receptor 2 JBrowse link 14 63,064,397 63,175,303 RGD:9068941
G HMOX1 heme oxygenase 1 JBrowse link 22 34,230,825 34,244,063 RGD:9068941
G TCN2 transcobalamin 2 JBrowse link 22 29,435,506 29,455,494 RGD:9068941
chronic myeloid leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCB1 ATP binding cassette subfamily B member 1 JBrowse link 7 93,147,217 93,355,231 RGD:9068941
G ABCC2 ATP binding cassette subfamily C member 2 JBrowse link 10 99,889,021 99,947,452 RGD:9068941
G ABCG2 ATP binding cassette subfamily G member 2 (Junior blood group) JBrowse link 4 91,101,321 91,170,418 RGD:9068941
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 9 130,482,852 130,652,941 RGD:9068941
RGD:7240710
G AGT angiotensinogen JBrowse link 1 211,279,015 211,291,044 RGD:9068941
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 105,211,645 105,236,756 RGD:9068941
G ALOX5 arachidonate 5-lipoxygenase JBrowse link 10 45,639,946 45,710,016 RGD:9068941
G ARNTL aryl hydrocarbon receptor nuclear translocator like JBrowse link 11 13,163,028 13,240,376 RGD:9068941
G BCL2L1 BCL2 like 1 JBrowse link 20 29,088,055 29,147,066 RGD:9068941
G BCR BCR activator of RhoGEF and GTPase JBrowse link 22 21,803,806 21,922,123 RGD:7240710
RGD:9068941
G BIRC5 baculoviral IAP repeat containing 5 JBrowse link 17 77,842,724 77,854,159 RGD:9068941
G BRAF B-Raf proto-oncogene, serine/threonine kinase JBrowse link 7 145,124,291 145,327,115 RGD:9068941
G CA9 carbonic anhydrase 9 JBrowse link 9 36,328,205 36,335,474 RGD:9068941
G CD36 CD36 molecule JBrowse link 7 86,228,856 86,305,865 RGD:9068941
G CD40 CD40 molecule JBrowse link 20 43,541,619 43,552,994 RGD:9068941
G CDKN1B cyclin dependent kinase inhibitor 1B JBrowse link 12 13,120,306 13,125,541 RGD:9068941
G CDKN2A cyclin dependent kinase inhibitor 2A JBrowse link 9 22,420,748 22,447,243 RGD:9068941
G CHORDC1 cysteine and histidine rich domain containing 1 JBrowse link 11 88,660,038 88,689,535 RGD:9068941
G CRKL CRK like proto-oncogene, adaptor protein JBrowse link 22 19,632,359 19,668,858 RGD:9068941
G CRY1 cryptochrome circadian regulator 1 JBrowse link 12 107,952,836 108,052,484 RGD:9068941
G CRY2 cryptochrome circadian regulator 2 JBrowse link 11 46,293,874 46,329,759 RGD:9068941
G CSF3R colony stimulating factor 3 receptor JBrowse link 1 36,897,148 36,914,398 RGD:9068941
G DNMT1 DNA methyltransferase 1 JBrowse link 19 10,342,478 10,390,397 RGD:9068941
G DNMT3A DNA methyltransferase 3 alpha JBrowse link 2A 25,331,095 25,441,785 RGD:9068941
G DNMT3B DNA methyltransferase 3 beta JBrowse link 20 30,169,081 30,215,487 RGD:9068941
G E2F1 E2F transcription factor 1 JBrowse link 20 31,103,764 31,115,211 RGD:9068941
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 19 50,897,004 50,915,849 RGD:9068941
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 7 153,017,590 153,059,726 RGD:9068941
G FAS Fas cell surface death receptor JBrowse link 10 89,199,070 89,244,884 RGD:9068941
G FASLG Fas ligand JBrowse link 1 151,868,430 151,876,281 RGD:9068941
G FCGR2A Fc fragment of IgG receptor IIa RGD:9068941
G GAB2 GRB2 associated binding protein 2 JBrowse link 11 76,896,691 76,965,955 RGD:9068941
G GPX1 glutathione peroxidase 1 JBrowse link 3 50,360,736 50,362,274 RGD:9068941
G GSTP1 glutathione S-transferase pi 1 JBrowse link 11 66,253,421 66,256,472 RGD:9068941
G HES1 hes family bHLH transcription factor 1 JBrowse link 3 201,749,044 201,751,591 RGD:9068941
G HMMR hyaluronan mediated motility receptor JBrowse link 5 165,614,127 165,645,478 RGD:9068941
G HMOX1 heme oxygenase 1 JBrowse link 22 34,230,825 34,244,063 RGD:9068941
G HSPA5 heat shock protein family A (Hsp70) member 5 JBrowse link 9 124,865,211 124,870,458 RGD:9068941
G IFNA2 interferon alpha 2 JBrowse link 9 21,862,557 21,863,690 RGD:9068941
G IL10 interleukin 10 JBrowse link 1 186,648,289 186,653,155 RGD:9068941
G IL1B interleukin 1 beta JBrowse link 2A 113,846,299 113,853,424 RGD:9068941
G IL1RN interleukin 1 receptor antagonist JBrowse link 2A 114,061,182 114,077,048 RGD:9068941
G INSL6 insulin like 6 JBrowse link 9 5,192,023 5,213,827 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 9 5,006,271 5,156,626 RGD:9068941
G KIT KIT proto-oncogene, receptor tyrosine kinase JBrowse link 4 75,761,946 75,844,473 RGD:9068941
G LOC100972994 HLA class II histocompatibility antigen, DQ beta 1 chain JBrowse link 6 33,353,599 33,360,284 RGD:9068941
G LOC100976184 cytochrome P450 1A1 JBrowse link 15 73,284,566 73,290,636 RGD:9068941
G LOC100976333 cytochrome P450 3A5 JBrowse link 7 105,123,437 105,155,322 RGD:9068941
G MAPK14 mitogen-activated protein kinase 14 JBrowse link 6 36,788,233 36,871,114 RGD:9068941
G MDM2 MDM2 proto-oncogene JBrowse link 12 69,102,083 69,133,278 RGD:9068941
G MLF1 myeloid leukemia factor 1 JBrowse link 3 163,654,983 163,689,688 RGD:9068941
G MTHFR methylenetetrahydrofolate reductase JBrowse link 1 11,766,334 11,785,645 RGD:9068941
G NCSTN nicastrin JBrowse link 1 139,618,229 139,633,911 RGD:9068941
G NPM1 nucleophosmin 1 JBrowse link 5 173,490,197 173,510,657 RGD:9068941
G NQO1 NAD(P)H quinone dehydrogenase 1 JBrowse link 16 69,472,529 69,489,731 RGD:9068941
G NRAS NRAS proto-oncogene, GTPase JBrowse link 1 122,890,505 122,903,585 RGD:9068941
G PECAM1 platelet and endothelial cell adhesion molecule 1 JBrowse link 17 63,511,784 63,601,241 RGD:9068941
G PER1 period circadian regulator 1 JBrowse link 17 48,234,360 48,250,391 RGD:9068941
G PER2 period circadian regulator 2 JBrowse link 2B 244,328,122 244,371,040 RGD:9068941
G PER3 period circadian regulator 3 JBrowse link 1 7,795,549 7,855,922 RGD:9068941
G PRTN3 proteinase 3 JBrowse link 19 810,237 817,588 RGD:9068941
G SETBP1 SET binding protein 1 JBrowse link 18 41,521,063 41,890,262 RGD:9068941
G SH2B3 SH2B adaptor protein 3 JBrowse link 12 112,371,797 112,418,746 RGD:9068941
G SIPA1 signal-induced proliferation-associated 1 JBrowse link 11 64,332,322 64,345,177 RGD:9068941
G SMAD4 SMAD family member 4 JBrowse link 18 47,692,311 47,802,530 RGD:9068941
G SRSF1 serine and arginine rich splicing factor 1 JBrowse link 17 56,937,295 56,944,874 RGD:9068941
G TERT telomerase reverse transcriptase JBrowse link 5 1,300,397 1,338,241 RGD:9068941
G TGFB1 transforming growth factor beta 1 JBrowse link 19 46,831,659 46,852,973 RGD:9068941
G VEGFA vascular endothelial growth factor A JBrowse link 6 44,651,855 44,666,353 RGD:9068941
G WT1 WT1 transcription factor JBrowse link 11 32,238,720 32,282,879 RGD:9068941
G XRCC1 X-ray repair cross complementing 1 JBrowse link 19 49,093,928 49,125,723 RGD:9068941
chronic myelomonocytic leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ASXL1 ASXL transcriptional regulator 1 JBrowse link 20 29,773,836 29,852,433 RGD:9068941
G CDKN2B cyclin dependent kinase inhibitor 2B JBrowse link 9 22,455,662 22,462,156 RGD:9068941
G CSF3R colony stimulating factor 3 receptor JBrowse link 1 36,897,148 36,914,398 RGD:9068941
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 7 153,017,590 153,059,726 RGD:9068941
G KDM6A lysine demethylase 6A JBrowse link X 45,127,382 45,362,029 RGD:9068941
G NRAS NRAS proto-oncogene, GTPase JBrowse link 1 122,890,505 122,903,585 RGD:9068941
G TET2 tet methylcytosine dioxygenase 2 JBrowse link 4 108,225,209 108,358,400 RGD:9068941
Chronic Myeloproliferative Disorder with Eosinophilia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFRB platelet derived growth factor receptor beta JBrowse link 5 151,543,581 151,585,630 RGD:7240710
RGD:9068941
chronic neutrophilic leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CSF3R colony stimulating factor 3 receptor JBrowse link 1 36,897,148 36,914,398 RGD:9068941
essential thrombocythemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATG2B autophagy related 2B JBrowse link 14 96,233,322 96,314,881 RGD:9068941
G BDKRB1 bradykinin receptor B1 JBrowse link 14 96,208,312 96,221,049 RGD:9068941
G BDKRB2 bradykinin receptor B2 JBrowse link 14 96,157,122 96,196,253 RGD:9068941
G C14H14orf132 chromosome 14 C14orf132 homolog JBrowse link 14 95,992,446 96,040,079 RGD:9068941
G CALR calreticulin JBrowse link 19 13,242,900 13,249,416 RGD:7240710
RGD:9068941
G CD36 CD36 molecule JBrowse link 7 86,228,856 86,305,865 RGD:9068941
G CD40LG CD40 ligand JBrowse link X 136,042,849 136,055,158 RGD:9068941
G ELANE elastase, neutrophil expressed JBrowse link 19 820,455 828,181 RGD:9068941
G FGF2 fibroblast growth factor 2 JBrowse link 4 126,149,750 126,220,774 RGD:9068941
G GSKIP GSK3B interacting protein JBrowse link 14 96,331,789 96,339,378 RGD:9068941
G IFNA2 interferon alpha 2 JBrowse link 9 21,862,557 21,863,690 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 9 5,006,271 5,156,626 RGD:9068941
G MPL MPL proto-oncogene, thrombopoietin receptor JBrowse link 1 44,018,395 44,034,492 RGD:9068941
G MYB MYB proto-oncogene, transcription factor JBrowse link 6 136,974,525 137,086,194 RGD:9068941
G PDGFA platelet derived growth factor subunit A JBrowse link 7 872,204 888,870 RGD:9068941
G PDGFB platelet derived growth factor subunit B JBrowse link 22 37,944,018 37,964,883 RGD:9068941
G SH2B3 SH2B adaptor protein 3 JBrowse link 12 112,371,797 112,418,746 RGD:7240710
RGD:9068941
G TCL1A T cell leukemia/lymphoma 1A JBrowse link 14 95,664,120 95,667,375 RGD:9068941
G TGFB1 transforming growth factor beta 1 JBrowse link 19 46,831,659 46,852,973 RGD:9068941
G THPO thrombopoietin JBrowse link 3 189,891,025 189,897,429 RGD:7240710
RGD:9068941
G VCAM1 vascular cell adhesion molecule 1 JBrowse link 1 102,091,121 102,108,494 RGD:9068941
G VWF von Willebrand factor JBrowse link 12 5,990,612 6,166,632 RGD:9068941
familial chronic myelocytic leukemia-like syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IRF8 interferon regulatory factor 8 JBrowse link 16 85,905,334 85,929,073 RGD:9068941
Familial Myelofibrosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GATA1 GATA binding protein 1 JBrowse link X 48,945,394 48,953,126 RGD:9068941
G MPL MPL proto-oncogene, thrombopoietin receptor JBrowse link 1 44,018,395 44,034,492 RGD:9068941
G VPS45 vacuolar protein sorting 45 homolog JBrowse link 1 129,065,430 129,142,990 RGD:9068941
juvenile myelomonocytic leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKAP12 A-kinase anchoring protein 12 JBrowse link 6 153,839,496 153,873,925 RGD:9068941
G ARHGAP26 Rho GTPase activating protein 26 JBrowse link 5 144,234,924 144,692,794 RGD:7240710
RGD:9068941
G ASXL1 ASXL transcriptional regulator 1 JBrowse link 20 29,773,836 29,852,433 RGD:9068941
G CBL Cbl proto-oncogene JBrowse link 11 117,973,187 118,076,459 RGD:9068941
RGD:7240710
G CSF2 colony stimulating factor 2 JBrowse link 5 133,660,775 133,663,146 RGD:9068941
G DNMT3A DNA methyltransferase 3 alpha JBrowse link 2A 25,331,095 25,441,785 RGD:9068941
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 7 153,017,590 153,059,726 RGD:9068941
G FLT3 fms related tyrosine kinase 3 JBrowse link 13 27,627,178 27,694,863 RGD:9068941
G GATA2 GATA binding protein 2 JBrowse link 3 132,890,508 132,899,035 RGD:9068941
G JAK3 Janus kinase 3 JBrowse link 19 18,283,157 18,304,641 RGD:9068941
G KRAS KRAS proto-oncogene, GTPase JBrowse link 12 63,679,293 63,724,335 RGD:9068941
G NF1 neurofibromin 1 JBrowse link 17 26,160,857 26,439,295 RGD:7240710
RGD:9068941
G NRAS NRAS proto-oncogene, GTPase JBrowse link 1 122,890,505 122,903,585 RGD:9068941
G PTPN11 protein tyrosine phosphatase non-receptor type 11 JBrowse link 12 113,412,077 113,503,762 RGD:7240710
RGD:9068941
G RAC2 Rac family small GTPase 2 JBrowse link 22 35,973,229 35,992,026 RGD:9068941
G RRAS RAS related JBrowse link 19 55,569,465 55,571,444 RGD:9068941
G RRAS2 RAS related 2 JBrowse link 11 14,073,679 14,154,027 RGD:9068941
G RUNX1 RUNX family transcription factor 1 JBrowse link 21 34,526,631 34,788,930 RGD:9068941
G SETBP1 SET binding protein 1 JBrowse link 18 41,521,063 41,890,262 RGD:9068941
G SH2B3 SH2B adaptor protein 3 JBrowse link 12 112,371,797 112,418,746 RGD:9068941
G ZRSR2 zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2 JBrowse link X 15,771,738 15,804,931 RGD:9068941
Leukemoid Reaction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G JAK3 Janus kinase 3 JBrowse link 19 18,283,157 18,304,641 RGD:9068941
multiple myeloma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCG2 ATP binding cassette subfamily G member 2 (Junior blood group) JBrowse link 4 91,101,321 91,170,418 RGD:9068941
G ALB albumin JBrowse link 4 56,605,322 56,622,418 RGD:9068941
G APOE apolipoprotein E JBrowse link 19 50,459,906 50,463,490 RGD:9068941
G B2M beta-2-microglobulin JBrowse link 15 41,836,321 41,842,991 RGD:9068941
G BCL2 BCL2 apoptosis regulator JBrowse link 18 59,797,184 59,993,298 RGD:9068941
G BCL2L1 BCL2 like 1 JBrowse link 20 29,088,055 29,147,066 RGD:9068941
G BCL2L10 BCL2 like 10 JBrowse link 15 49,376,576 49,380,109 RGD:9068941
G BNIP3 BCL2 interacting protein 3 JBrowse link 10 132,857,375 132,871,628 RGD:9068941
G BRAF B-Raf proto-oncogene, serine/threonine kinase JBrowse link 7 145,124,291 145,327,115 RGD:9068941
G BTG1 BTG anti-proliferation factor 1 JBrowse link 12 92,991,624 92,994,379 RGD:9068941
G CBL Cbl proto-oncogene JBrowse link 11 117,973,187 118,076,459 RGD:9068941
G CBX7 chromobox 7 JBrowse link 22 37,854,049 37,876,861 RGD:9068941
G CCL2 C-C motif chemokine ligand 2 JBrowse link 17 22,821,336 22,823,271 RGD:9068941
G CCND1 cyclin D1 JBrowse link 11 68,029,134 68,041,553 RGD:7240710
RGD:9068941
G CCND2 cyclin D2 JBrowse link 12 4,309,272 4,340,893 RGD:9068941
G CCND3 cyclin D3 JBrowse link 6 42,820,569 42,932,944 RGD:9068941
G CD40 CD40 molecule JBrowse link 20 43,541,619 43,552,994 RGD:9068941
G CD40LG CD40 ligand JBrowse link X 136,042,849 136,055,158 RGD:9068941
G CD46 CD46 molecule JBrowse link 1 188,138,616 188,182,046 RGD:9068941
G CD86 CD86 molecule JBrowse link 3 126,059,008 126,124,339 RGD:9068941
G CDK4 cyclin dependent kinase 4 JBrowse link 12 31,434,594 31,438,876 RGD:9068941
G CDKN2A cyclin dependent kinase inhibitor 2A JBrowse link 9 22,420,748 22,447,243 RGD:9068941
G CHI3L1 chitinase 3 like 1 JBrowse link 1 183,073,287 183,083,229 RGD:9068941
G CRBN cereblon JBrowse link 3 3,195,361 3,225,345 RGD:9068941
G CSF2 colony stimulating factor 2 JBrowse link 5 133,660,775 133,663,146 RGD:9068941
G CSF3 colony stimulating factor 3 JBrowse link 17 17,491,272 17,493,729 RGD:9068941
G CTLA4 cytotoxic T-lymphocyte associated protein 4 JBrowse link 2B 209,239,417 209,244,498 RGD:9068941
G ENG endoglin JBrowse link 9 127,605,608 127,644,641 RGD:9068941
G EPHX1 epoxide hydrolase 1 JBrowse link 1 206,272,866 206,307,581 RGD:9068941
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 19 50,951,674 50,994,600 RGD:9068941
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 19 50,897,004 50,915,849 RGD:9068941
G FASLG Fas ligand JBrowse link 1 151,868,430 151,876,281 RGD:9068941
G FCGR2A Fc fragment of IgG receptor IIa RGD:9068941
G FGFR3 fibroblast growth factor receptor 3 JBrowse link 4 1,843,780 1,858,635 RGD:9068941
G FGG fibrinogen gamma chain JBrowse link 4 158,788,761 158,797,460 RGD:9068941
G FLT3LG fms related tyrosine kinase 3 ligand JBrowse link 19 55,410,448 55,422,545 RGD:9068941
G GPX1 glutathione peroxidase 1 JBrowse link 3 50,360,736 50,362,274 RGD:9068941
G GSTM1 glutathione S-transferase mu 1 JBrowse link 1 128,003,736 128,009,696 RGD:9068941
G GSTP1 glutathione S-transferase pi 1 JBrowse link 11 66,253,421 66,256,472 RGD:9068941
G HFE homeostatic iron regulator JBrowse link 6 26,580,358 26,588,591 RGD:9068941
G HK1 hexokinase 1 JBrowse link 10 68,289,288 68,401,045 RGD:9068941
G HRAS HRas proto-oncogene, GTPase JBrowse link 11 568,305 571,078 RGD:9068941
G HSPB1 heat shock protein family B (small) member 1 JBrowse link 7 82,751,385 82,753,109 RGD:9068941
G ICAM1 intercellular adhesion molecule 1 JBrowse link 19 10,484,414 10,500,605 RGD:9068941
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 JBrowse link 2B 213,599,036 213,628,840 RGD:9068941
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 JBrowse link 15 87,972,883 87,991,270 RGD:9068941
G IFNA2 interferon alpha 2 JBrowse link 9 21,862,557 21,863,690 RGD:9068941
G IL10 interleukin 10 JBrowse link 1 186,648,289 186,653,155 RGD:9068941
G IL1A interleukin 1 alpha JBrowse link 2A 113,784,854 113,795,801 RGD:9068941
G IL1B interleukin 1 beta JBrowse link 2A 113,846,299 113,853,424 RGD:9068941
G IL1RN interleukin 1 receptor antagonist JBrowse link 2A 114,061,182 114,077,048 RGD:9068941
G IL4R interleukin 4 receptor JBrowse link 16 27,686,760 27,737,445 RGD:9068941
G IL6 interleukin 6 JBrowse link 7 23,027,560 23,032,419 RGD:9068941
G IRF4 interferon regulatory factor 4 JBrowse link 6 341,637 360,492 RGD:9068941
G KRAS KRAS proto-oncogene, GTPase JBrowse link 12 63,679,293 63,724,335 RGD:9068941
G LIG4 DNA ligase 4 JBrowse link 13 108,474,718 108,485,421 RGD:7240710
RGD:9068941
G LOC100976184 cytochrome P450 1A1 JBrowse link 15 73,284,566 73,290,636 RGD:9068941
G LOC100995695 cytochrome P450 2C19 JBrowse link 10 94,883,037 94,972,353 RGD:9068941
G LRRC56 leucine rich repeat containing 56 JBrowse link 11 571,886 588,750 RGD:9068941
G MAF MAF bZIP transcription factor JBrowse link 16 79,618,156 79,624,460 RGD:9068941
G MCL1 MCL1 apoptosis regulator, BCL2 family member JBrowse link 1 129,566,827 129,572,086 RGD:9068941
G MEFV MEFV innate immuity regulator, pyrin JBrowse link 16 3,354,981 3,368,970 RGD:9068941
G MET MET proto-oncogene, receptor tyrosine kinase JBrowse link 7 121,365,429 121,468,159 RGD:9068941
G MTHFR methylenetetrahydrofolate reductase JBrowse link 1 11,766,334 11,785,645 RGD:9068941
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase JBrowse link 1 217,352,707 217,461,313 RGD:9068941
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase JBrowse link 5 8,017,373 8,049,322 RGD:9068941
G MUC1 mucin 1, cell surface associated JBrowse link 1 134,141,969 134,146,791 RGD:9068941
G MYD88 MYD88 innate immune signal transduction adaptor JBrowse link 3 38,319,024 38,323,572 RGD:9068941
G NFKBIA NFKB inhibitor alpha JBrowse link 14 34,337,307 34,340,225 RGD:9068941
G NOTCH2 notch receptor 2 JBrowse link 1 117,537,162 117,612,840 RGD:9068941
G NQO1 NAD(P)H quinone dehydrogenase 1 JBrowse link 16 69,472,529 69,489,731 RGD:9068941
G NRAS NRAS proto-oncogene, GTPase JBrowse link 1 122,890,505 122,903,585 RGD:9068941
G NUAK1 NUAK family kinase 1 JBrowse link 12 107,037,632 107,113,163 RGD:9068941
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 1 206,812,981 206,860,356 RGD:9068941
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 3 184,355,789 184,441,997 RGD:9068941
G PON1 paraoxonase 1 JBrowse link 7 100,841,286 100,867,493 RGD:9068941
G PSORS1C2 psoriasis susceptibility 1 candidate 2 JBrowse link 6 31,748,923 31,750,739 RGD:9068941
G PTHLH parathyroid hormone like hormone JBrowse link 12 60,959,327 60,973,749 RGD:9068941
G PTPN11 protein tyrosine phosphatase non-receptor type 11 JBrowse link 12 113,412,077 113,503,762 RGD:9068941
G RANBP2 RAN binding protein 2 JBrowse link 2A 110,010,961 110,039,769 RGD:9068941
G RUNX1 RUNX family transcription factor 1 JBrowse link 21 34,526,631 34,788,930 RGD:9068941
G SOD2 superoxide dismutase 2 JBrowse link 6 162,576,082 162,589,960 RGD:9068941
G SPARC secreted protein acidic and cysteine rich JBrowse link 5 153,091,160 153,115,745 RGD:9068941
G SPP1 secreted phosphoprotein 1 JBrowse link 4 90,988,200 90,995,935 RGD:9068941
G TERT telomerase reverse transcriptase JBrowse link 5 1,300,397 1,338,241 RGD:9068941
G TFRC transferrin receptor JBrowse link 3 203,333,953 203,365,586 RGD:9068941
G TGFB1 transforming growth factor beta 1 JBrowse link 19 46,831,659 46,852,973 RGD:9068941
G TNF tumor necrosis factor JBrowse link 6 32,126,618 32,129,389 RGD:9068941
G TNFRSF10A TNF receptor superfamily member 10a JBrowse link 8 19,378,547 19,414,724 RGD:9068941
G TNFRSF13B TNF receptor superfamily member 13B JBrowse link 17 39,252,858 39,286,007 RGD:9068941
G TNFRSF17 TNF receptor superfamily member 17 JBrowse link 16 12,333,254 12,336,219 RGD:9068941
G TP53 tumor protein p53 JBrowse link 17 7,687,132 7,706,120 RGD:9068941
G TYMS thymidylate synthetase JBrowse link 18 17,295,182 17,310,311 RGD:9068941
G ULK4 unc-51 like kinase 4 JBrowse link 3 41,420,162 42,129,218 RGD:9068941
G VEGFA vascular endothelial growth factor A JBrowse link 6 44,651,855 44,666,353 RGD:9068941
G XPO5 exportin 5 JBrowse link 6 44,405,234 44,458,235 RGD:9068941
G XRCC4 X-ray repair cross complementing 4 JBrowse link 5 32,246,959 32,521,724 RGD:9068941
G XRCC5 X-ray repair cross complementing 5 JBrowse link 2B 221,972,607 222,072,318 RGD:9068941
myelodysplastic/myeloproliferative neoplasm term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DDX41 DEAD-box helicase 41 JBrowse link 5 179,874,281 179,880,685 RGD:9068941
G DIDO1 death inducer-obliterator 1 JBrowse link 20 60,556,923 60,617,265 RGD:9068941
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 7 153,017,590 153,059,726 RGD:9068941
myelofibrosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ASXL1 ASXL transcriptional regulator 1 JBrowse link 20 29,773,836 29,852,433 RGD:9068941
G ATG2B autophagy related 2B JBrowse link 14 96,233,322 96,314,881 RGD:9068941
G BDKRB1 bradykinin receptor B1 JBrowse link 14 96,208,312 96,221,049 RGD:9068941
G BDKRB2 bradykinin receptor B2 JBrowse link 14 96,157,122 96,196,253 RGD:9068941
G C14H14orf132 chromosome 14 C14orf132 homolog JBrowse link 14 95,992,446 96,040,079 RGD:9068941
G CALR calreticulin JBrowse link 19 13,242,900 13,249,416 RGD:7240710
RGD:9068941
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 19 50,951,674 50,994,600 RGD:9068941
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 19 50,897,004 50,915,849 RGD:9068941
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 7 153,017,590 153,059,726 RGD:9068941
G FLT3 fms related tyrosine kinase 3 JBrowse link 13 27,627,178 27,694,863 RGD:9068941
G FLT3LG fms related tyrosine kinase 3 ligand JBrowse link 19 55,410,448 55,422,545 RGD:9068941
G GATA1 GATA binding protein 1 JBrowse link X 48,945,394 48,953,126 RGD:9068941
G GSKIP GSK3B interacting protein JBrowse link 14 96,331,789 96,339,378 RGD:9068941
G HFE homeostatic iron regulator JBrowse link 6 26,580,358 26,588,591 RGD:9068941
G INSL6 insulin like 6 JBrowse link 9 5,192,023 5,213,827 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 9 5,006,271 5,156,626 RGD:7240710
RGD:9068941
G MPL MPL proto-oncogene, thrombopoietin receptor JBrowse link 1 44,018,395 44,034,492 RGD:7240710
RGD:9068941
G MYB MYB proto-oncogene, transcription factor JBrowse link 6 136,974,525 137,086,194 RGD:9068941
G NCOR2 nuclear receptor corepressor 2 JBrowse link 12 126,200,793 126,412,757 RGD:9068941
G SH2B3 SH2B adaptor protein 3 JBrowse link 12 112,371,797 112,418,746 RGD:7240710
RGD:9068941
G TCL1A T cell leukemia/lymphoma 1A JBrowse link 14 95,664,120 95,667,375 RGD:9068941
G TGFB1 transforming growth factor beta 1 JBrowse link 19 46,831,659 46,852,973 RGD:9068941
G TP53 tumor protein p53 JBrowse link 17 7,687,132 7,706,120 RGD:9068941
Myeloid Leukemia, Accelerated Phase term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BMI1 BMI1 proto-oncogene, polycomb ring finger JBrowse link 10 22,854,230 22,863,482 RGD:9068941
Myeloid Leukemia, Chronic-Phase term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 9 130,482,852 130,652,941 RGD:9068941
G BCR BCR activator of RhoGEF and GTPase JBrowse link 22 21,803,806 21,922,123 RGD:9068941
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 19 50,951,674 50,994,600 RGD:9068941
G GFI1 growth factor independent 1 transcriptional repressor JBrowse link 1 93,875,880 93,883,558 RGD:9068941
G GFI1B growth factor independent 1B transcriptional repressor JBrowse link 9 132,692,343 132,742,326 RGD:9068941
G LOC100976333 cytochrome P450 3A5 JBrowse link 7 105,123,437 105,155,322 RGD:9068941
myeloproliferative neoplasm term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CSF3R colony stimulating factor 3 receptor JBrowse link 1 36,897,148 36,914,398 RGD:9068941
G DDX41 DEAD-box helicase 41 JBrowse link 5 179,874,281 179,880,685 RGD:9068941
G ETV6 ETS variant 6 JBrowse link 12 12,035,107 12,179,537 RGD:9068941
G FGFR3 fibroblast growth factor receptor 3 JBrowse link 4 1,843,780 1,858,635 RGD:9068941
G INSL6 insulin like 6 JBrowse link 9 5,192,023 5,213,827 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 9 5,006,271 5,156,626 RGD:9068941
G JAK3 Janus kinase 3 JBrowse link 19 18,283,157 18,304,641 RGD:9068941
G KIT KIT proto-oncogene, receptor tyrosine kinase JBrowse link 4 75,761,946 75,844,473 RGD:9068941
G MPL MPL proto-oncogene, thrombopoietin receptor JBrowse link 1 44,018,395 44,034,492 RGD:9068941
G PDGFRB platelet derived growth factor receptor beta JBrowse link 5 151,543,581 151,585,630 RGD:9068941
G TET2 tet methylcytosine dioxygenase 2 JBrowse link 4 108,225,209 108,358,400 RGD:9068941
Noonan Syndrome-Like Disorder with or without Juvenile Myelomonocytic Leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CBL Cbl proto-oncogene JBrowse link 11 117,973,187 118,076,459 RGD:7240710
RGD:9068941
G PTPN11 protein tyrosine phosphatase non-receptor type 11 JBrowse link 12 113,412,077 113,503,762 RGD:9068941
plasmacytic leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD40 CD40 molecule JBrowse link 20 43,541,619 43,552,994 RGD:9068941
G TERT telomerase reverse transcriptase JBrowse link 5 1,300,397 1,338,241 RGD:9068941
polycythemia vera term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL2L1 BCL2 like 1 JBrowse link 20 29,088,055 29,147,066 RGD:9068941
G CD36 CD36 molecule JBrowse link 7 86,228,856 86,305,865 RGD:9068941
G ELANE elastase, neutrophil expressed JBrowse link 19 820,455 828,181 RGD:9068941
G EPOR erythropoietin receptor JBrowse link 19 11,635,248 11,642,383 RGD:9068941
G GSR glutathione-disulfide reductase JBrowse link 8 27,180,294 27,229,557 RGD:9068941
G GSTM1 glutathione S-transferase mu 1 JBrowse link 1 128,003,736 128,009,696 RGD:9068941
G HFE homeostatic iron regulator JBrowse link 6 26,580,358 26,588,591 RGD:9068941
G IFNA2 interferon alpha 2 JBrowse link 9 21,862,557 21,863,690 RGD:9068941
G INSL6 insulin like 6 JBrowse link 9 5,192,023 5,213,827 RGD:9068941
G JAK1 Janus kinase 1 JBrowse link 1 65,972,568 66,025,070 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 9 5,006,271 5,156,626 RGD:7240710
RGD:9068941
Thrombocythemia 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MPL MPL proto-oncogene, thrombopoietin receptor JBrowse link 1 44,018,395 44,034,492 RGD:7240710
RGD:9068941
Thrombocythemia 3 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G INSL6 insulin like 6 JBrowse link 9 5,192,023 5,213,827 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 9 5,006,271 5,156,626 RGD:7240710
RGD:9068941
Thrombocytopenia, Anemia, and Myelofibrosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MPIG6B megakaryocyte and platelet inhibitory receptor G6b JBrowse link 6 32,273,438 32,276,772 RGD:9068941
RGD:7240710
thrombocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CALR calreticulin JBrowse link 19 13,242,900 13,249,416 RGD:9068941
G CPB2 carboxypeptidase B2 RGD:9068941
G EPOR erythropoietin receptor JBrowse link 19 11,635,248 11,642,383 RGD:9068941
G IL1B interleukin 1 beta JBrowse link 2A 113,846,299 113,853,424 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 9 5,006,271 5,156,626 RGD:9068941
G MPL MPL proto-oncogene, thrombopoietin receptor JBrowse link 1 44,018,395 44,034,492 RGD:9068941
G THPO thrombopoietin JBrowse link 3 189,891,025 189,897,429 RGD:9068941
Thrombocytosis, Benign Familial Microcytic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MPL MPL proto-oncogene, thrombopoietin receptor JBrowse link 1 44,018,395 44,034,492 RGD:9068941
transient myeloproliferative syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GATA1 GATA binding protein 1 JBrowse link X 48,945,394 48,953,126 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 11835
    disease of anatomical entity 11487
      hematopoietic system disease 1277
        bone marrow disease 379
          myeloid neoplasm 214
            Acute Erythroblastic Leukemia + 13
            Chronic Myeloproliferative Disorder with Eosinophilia 1
            Leukemoid Reaction + 2
            Myeloproliferative Disease, Autosomal Recessive 0
            chronic myeloid leukemia + 79
            chronic neutrophilic leukemia 1
            multiple myeloma + 98
            myelodysplastic/myeloproliferative neoplasm + 29
            myelofibrosis + 25
            myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1 + 0
            myelophthisic anemia 0
            myeloproliferative neoplasm + 38
            thrombocytosis + 26
Path 2
Term Annotations click to browse term
  disease 11835
    disease of anatomical entity 11487
      Hemic and Lymphatic Diseases 1531
        hematopoietic system disease 1277
          Hematologic Neoplasms 724
            hematologic cancer 724
              bone marrow cancer 272
                myeloid neoplasm 214
                  Acute Erythroblastic Leukemia + 13
                  Chronic Myeloproliferative Disorder with Eosinophilia 1
                  Leukemoid Reaction + 2
                  Myeloproliferative Disease, Autosomal Recessive 0
                  chronic myeloid leukemia + 79
                  chronic neutrophilic leukemia 1
                  multiple myeloma + 98
                  myelodysplastic/myeloproliferative neoplasm + 29
                  myelofibrosis + 25
                  myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1 + 0
                  myelophthisic anemia 0
                  myeloproliferative neoplasm + 38
                  thrombocytosis + 26
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.