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ONTOLOGY REPORT - ANNOTATIONS


Term:myeloid neoplasm
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Accession:DOID:0070004 term browser browse the term
Definition:Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE.
Synonyms:exact_synonym: Myeloproliferative Disorder;   Myeloproliferative Disorders;   myeloma
 primary_id: MESH:D009196;   RDO:0004832
For additional species annotation, visit the Alliance of Genome Resources.


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myeloid neoplasm term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atg2b autophagy related 2B JBrowse link NW_004955438 18,080,641 18,153,490 RGD:9068941
G Bcr BCR activator of RhoGEF and GTPase JBrowse link NW_004955455 7,598,794 7,727,386 RGD:9068941
G Cbl Cbl proto-oncogene JBrowse link NW_004955412 20,307,011 20,388,539 RGD:9068941
G Cd36 CD36 molecule JBrowse link NW_004955410 5,003,720 5,120,903 RGD:9068941
G Csf1r colony stimulating factor 1 receptor JBrowse link NW_004955415 4,434,486 4,462,505 RGD:9068941
G Egr1 early growth response 1 JBrowse link NW_004955418 2,001,509 2,005,269 RGD:9068941
G Etv6 ETS variant 6 JBrowse link NW_004955413 8,698,412 8,912,011 RGD:9068941
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link NW_004955491 4,215,353 4,292,229 RGD:9068941
G F3 coagulation factor III, tissue factor JBrowse link NW_004955423 254,060 264,448 RGD:9068941
G Fgfr1 fibroblast growth factor receptor 1 JBrowse link NW_004955463 14,013,247 14,064,354 RGD:9068941
G Fgfr1op2 FGFR1 oncogene partner 2 JBrowse link NW_004955413 21,814,133 21,843,105 RGD:9068941
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link NW_004955514 1,030,244 1,038,590 RGD:9068941
G Flt3 fms related tyrosine kinase 3 JBrowse link NW_004955497 7,357,533 7,441,215 RGD:9068941
G Gfi1 growth factor independent 1 transcriptional repressor JBrowse link NW_004955423 2,024,084 2,032,530 RGD:9068941
G Gfi1b growth factor independent 1B transcriptional repressor JBrowse link NW_004955513 2,273,267 2,281,850 RGD:9068941
G Gpx1 glutathione peroxidase 1 JBrowse link NW_004955532 1,298,336 1,298,830 RGD:9068941
G Gskip GSK3B interacting protein JBrowse link NW_004955438 18,153,564 18,174,980 RGD:9068941
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link NW_004955419 3,055,420 3,060,208 RGD:9068941
G Insl6 insulin like 6 JBrowse link NW_004955434 9,349,033 9,355,817 RGD:9068941
G Irf4 interferon regulatory factor 4 JBrowse link NW_004955465 12,497,534 12,512,529 RGD:9068941
G Irf8 interferon regulatory factor 8 JBrowse link NW_004955541 973,004 988,493 RGD:9068941
G Jak2 Janus kinase 2 JBrowse link NW_004955434 9,227,897 9,341,208 RGD:9068941
G Kras KRAS proto-oncogene, GTPase JBrowse link NW_004955413 20,298,852 20,328,756 RGD:9068941
G Mecom MDS1 and EVI1 complex locus JBrowse link NW_004955448 18,259,847 18,542,085 RGD:9068941
G Mthfr methylenetetrahydrofolate reductase JBrowse link NW_004955486 2,096,379 2,112,240 RGD:9068941
G Npm1 nucleophosmin 1 JBrowse link NW_004955408 24,151,070 24,218,783 RGD:9068941
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link NW_004955484 7,012,373 7,028,182 RGD:9068941
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 JBrowse link NW_004955465 10,186,928 10,200,098 RGD:9068941
G Nras NRAS proto-oncogene, GTPase JBrowse link NW_004955435 18,001,517 18,009,105 RGD:9068941
G Runx1 RUNX family transcription factor 1 JBrowse link NW_004955407 34,108,653 34,342,657 RGD:9068941
G Zmym2 zinc finger MYM-type containing 2 JBrowse link NW_004955497 778,641 895,376 RGD:9068941
Acute Erythroblastic Leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase JBrowse link NW_004955469 9,203,433 9,227,526 RGD:9068941
G Dhodh dihydroorotate dehydrogenase (quinone) JBrowse link NW_004955484 4,699,743 4,713,466 RGD:9068941
G Umps uridine monophosphate synthetase JBrowse link NW_004955427 23,825,529 23,841,427 RGD:9068941
Acute Erythroleukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddx41 DEAD-box helicase 41 JBrowse link NW_004955408 29,748,091 29,753,610 RGD:9068941
G Erbb3 erb-b2 receptor tyrosine kinase 3 JBrowse link NW_004955458 3,683,126 3,701,752 RGD:9068941
G Flt3 fms related tyrosine kinase 3 JBrowse link NW_004955497 7,357,533 7,441,215 RGD:9068941
G Gfi1b growth factor independent 1B transcriptional repressor JBrowse link NW_004955513 2,273,267 2,281,850 RGD:9068941
G Hoxb9 homeobox B9 JBrowse link NW_004955451 12,616,465 12,616,926 RGD:9068941
G Kmt2a lysine methyltransferase 2A JBrowse link NW_004955412 19,586,435 19,670,149 RGD:9068941
G Npm1 nucleophosmin 1 JBrowse link NW_004955408 24,151,070 24,218,783 RGD:9068941
G Nup98 nucleoporin 98 JBrowse link NW_004955414 19,499,577 19,607,075 RGD:9068941
G Rb1 RB transcriptional corepressor 1 JBrowse link NW_004955431 1,960,765 2,124,576 RGD:9068941
G Tp53 tumor protein p53 JBrowse link NW_004955467 9,241,391 9,256,716 RGD:9068941
atypical chronic myeloid leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgfr1 fibroblast growth factor receptor 1 JBrowse link NW_004955463 14,013,247 14,064,354 RGD:9068941
G Setbp1 SET binding protein 1 JBrowse link NW_004955402 30,380,346 30,738,869 RGD:9068941
Blast Crisis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcr BCR activator of RhoGEF and GTPase JBrowse link NW_004955455 7,598,794 7,727,386 RGD:9068941
G Esr2 estrogen receptor 2 JBrowse link NW_004955466 5,587,003 5,644,765 RGD:9068941
G Hmox1 heme oxygenase 1 JBrowse link NW_004955405 43,124,447 43,128,873 RGD:9068941
G Tcn2 transcobalamin 2 JBrowse link NW_004955455 4,827,030 4,849,810 RGD:9068941
chronic myeloid leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1 ATP binding cassette subfamily B member 1 JBrowse link NW_004955432 4,911,774 5,085,349 RGD:9068941
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link NW_004955507 5,724,788 5,791,281 RGD:9068941
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) JBrowse link NW_004955474 12,365,903 12,408,715 RGD:9068941
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link NW_004955513 652,048 799,182 RGD:7240710
RGD:9068941
G Agt angiotensinogen JBrowse link NW_004955492 7,863,662 7,874,863 RGD:9068941
G Akt1 AKT serine/threonine kinase 1 JBrowse link NW_004955538 3,208,711 3,224,386 RGD:9068941
G Alox5 arachidonate 5-lipoxygenase JBrowse link NW_004955546 2,495,226 2,550,909 RGD:9068941
G Arntl aryl hydrocarbon receptor nuclear translocator like JBrowse link NW_004955414 28,652,663 28,748,360 RGD:9068941
G Bcl2l1 BCL2 like 1 JBrowse link NW_004955422 29,254,440 29,307,104 RGD:9068941
G Bcr BCR activator of RhoGEF and GTPase JBrowse link NW_004955455 7,598,794 7,727,386 RGD:7240710
RGD:9068941
G Braf B-Raf proto-oncogene, serine/threonine kinase JBrowse link NW_004955494 2,567,238 2,712,708 RGD:9068941
G Ca9 carbonic anhydrase 9 JBrowse link NW_004955472 619,084 625,570 RGD:9068941
G Cd36 CD36 molecule JBrowse link NW_004955410 5,003,720 5,120,903 RGD:9068941
G Cd40 CD40 molecule JBrowse link NW_004955445 11,191,817 11,202,156 RGD:9068941
G Cdkn1b cyclin dependent kinase inhibitor 1B JBrowse link NW_004955413 9,615,542 9,620,542 RGD:9068941
G Chordc1 cysteine and histidine rich domain containing 1 JBrowse link NW_004955414 3,699,652 3,717,200 RGD:9068941
G Crkl CRK like proto-oncogene, adaptor protein JBrowse link NW_004955442 19,358,202 19,388,552 RGD:9068941
G Cry1 cryptochrome circadian regulator 1 JBrowse link NW_004955405 40,878,227 40,941,664 RGD:9068941
G Cry2 cryptochrome circadian regulator 2 JBrowse link NW_004955422 2,084,020 2,114,980 RGD:9068941
G Csf3r colony stimulating factor 3 receptor JBrowse link NW_004955452 14,409,484 14,425,818 RGD:9068941
G Dnmt1 DNA methyltransferase 1 JBrowse link NW_004955495 1,465,529 1,505,379 RGD:9068941
G Dnmt3a DNA methyltransferase 3 alpha JBrowse link NW_004955469 7,264,431 7,367,059 RGD:9068941
G Dnmt3b DNA methyltransferase 3 beta JBrowse link NW_004955422 28,380,595 28,427,012 RGD:9068941
G E2f1 E2F transcription factor 1 JBrowse link NW_004955422 27,638,625 27,643,261 RGD:9068941
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link NW_004955555 2,355,005 2,369,599 RGD:9068941
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link NW_004955491 4,215,353 4,292,229 RGD:9068941
G Fas Fas cell surface death receptor JBrowse link NW_004955425 3,961,671 3,987,513 RGD:9068941
G Faslg Fas ligand JBrowse link NW_004955406 13,098,479 13,107,045 RGD:9068941
G Gab2 GRB2 associated binding protein 2 JBrowse link NW_004955414 13,640,713 13,754,401 RGD:9068941
G Gpx1 glutathione peroxidase 1 JBrowse link NW_004955532 1,298,336 1,298,830 RGD:9068941
G Gstp1 glutathione S-transferase pi 1 JBrowse link NW_004955422 17,914,228 17,916,918 RGD:9068941
G Hes1 hes family bHLH transcription factor 1 JBrowse link NW_004955420 14,565,921 14,568,447 RGD:9068941
G Hmmr hyaluronan mediated motility receptor JBrowse link NW_004955408 16,865,066 16,895,918 RGD:9068941
G Hmox1 heme oxygenase 1 JBrowse link NW_004955405 43,124,447 43,128,873 RGD:9068941
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link NW_004955419 3,055,420 3,060,208 RGD:9068941
G Il10 interleukin 10 JBrowse link NW_004955406 42,307,789 42,312,255 RGD:9068941
G Il1b interleukin 1 beta JBrowse link NW_004955470 1,486,936 1,491,888 RGD:9068941
G Il1rn interleukin 1 receptor antagonist JBrowse link NW_004955470 1,145,022 1,159,413 RGD:9068941
G Insl6 insulin like 6 JBrowse link NW_004955434 9,349,033 9,355,817 RGD:9068941
G Jak2 Janus kinase 2 JBrowse link NW_004955434 9,227,897 9,341,208 RGD:9068941
G Kit KIT proto-oncogene, receptor tyrosine kinase JBrowse link NW_004955447 16,149,014 16,226,151 RGD:9068941
G LOC102010850 cytochrome P450 1A1 JBrowse link NW_004955450 3,183,958 3,189,488 RGD:9068941
G Mapk14 mitogen-activated protein kinase 14 JBrowse link NW_004955437 3,836,331 3,884,083 RGD:9068941
G Mdm2 MDM2 proto-oncogene JBrowse link NW_004955458 15,264,028 15,287,290 RGD:9068941
G Mlf1 myeloid leukemia factor 1 JBrowse link NW_004955448 9,345,303 9,383,366 RGD:9068941
G Mthfr methylenetetrahydrofolate reductase JBrowse link NW_004955486 2,096,379 2,112,240 RGD:9068941
G Ncstn nicastrin JBrowse link NW_004955468 12,111,078 12,126,404 RGD:9068941
G Npm1 nucleophosmin 1 JBrowse link NW_004955408 24,151,070 24,218,783 RGD:9068941
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link NW_004955484 7,012,373 7,028,182 RGD:9068941
G Nras NRAS proto-oncogene, GTPase JBrowse link NW_004955435 18,001,517 18,009,105 RGD:9068941
G Pecam1 platelet and endothelial cell adhesion molecule 1 JBrowse link NW_004955478 7,448,584 7,531,860 RGD:9068941
G Per1 period circadian regulator 1 JBrowse link NW_004955467 8,798,436 8,813,369 RGD:9068941
G Per2 period circadian regulator 2 JBrowse link NW_004955542 2,331,547 2,369,011 RGD:9068941
G Per3 period circadian regulator 3 JBrowse link NW_004955486 5,058,602 5,101,480 RGD:9068941
G Prame preferentially expressed antigen in melanoma JBrowse link NW_004955455 6,921,420 6,930,453 RGD:9068941
G Setbp1 SET binding protein 1 JBrowse link NW_004955402 30,380,346 30,738,869 RGD:9068941
G Sh2b3 SH2B adaptor protein 3 JBrowse link NW_004955482 8,079,905 8,100,791 RGD:9068941
G Sipa1 signal-induced proliferation-associated 1 JBrowse link NW_004955422 19,615,440 19,627,195 RGD:9068941
G Smad4 SMAD family member 4 JBrowse link NW_004955402 35,956,080 36,001,746 RGD:9068941
G Srsf1 serine and arginine rich splicing factor 1 JBrowse link NW_004955451 4,992,634 4,996,619 RGD:9068941
G Tert telomerase reverse transcriptase JBrowse link NW_004955504 649,248 669,796 RGD:9068941
G Tgfb1 transforming growth factor beta 1 JBrowse link NW_004955555 274,405 288,441 RGD:9068941
G Vegfa vascular endothelial growth factor A JBrowse link NW_004955437 9,527,445 9,541,908 RGD:9068941
G Wt1 WT1 transcription factor JBrowse link NW_004955476 10,464,688 10,504,473 RGD:9068941
G Xrcc1 X-ray repair cross complementing 1 JBrowse link NW_004955555 1,293,416 1,315,839 RGD:9068941
chronic myelomonocytic leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asxl1 ASXL transcriptional regulator 1 JBrowse link NW_004955422 28,662,392 28,721,896 RGD:9068941
G Cdkn2b cyclin dependent kinase inhibitor 2B JBrowse link NW_004955472 12,275,613 12,280,141 RGD:9068941
G Csf3r colony stimulating factor 3 receptor JBrowse link NW_004955452 14,409,484 14,425,818 RGD:9068941
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link NW_004955491 4,215,353 4,292,229 RGD:9068941
G Kdm6a lysine demethylase 6A JBrowse link NW_004955516 3,151,350 3,346,832 RGD:9068941
G Nras NRAS proto-oncogene, GTPase JBrowse link NW_004955435 18,001,517 18,009,105 RGD:9068941
G Tet2 tet methylcytosine dioxygenase 2 JBrowse link NW_004955496 3,885,684 3,963,056 RGD:9068941
Chronic Myeloproliferative Disorder with Eosinophilia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfrb platelet derived growth factor receptor beta JBrowse link NW_004955415 4,365,848 4,403,317 RGD:7240710
RGD:9068941
chronic neutrophilic leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Csf3r colony stimulating factor 3 receptor JBrowse link NW_004955452 14,409,484 14,425,818 RGD:9068941
essential thrombocythemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atg2b autophagy related 2B JBrowse link NW_004955438 18,080,641 18,153,490 RGD:9068941
G Bdkrb1 bradykinin receptor B1 JBrowse link NW_004955438 16,500,219 16,505,394 RGD:9068941
G Bdkrb2 bradykinin receptor B2 JBrowse link NW_004955438 16,514,300 16,537,160 RGD:9068941
G Calr calreticulin JBrowse link NW_004955415 31,985,147 31,989,372 RGD:7240710
RGD:9068941
G Cd36 CD36 molecule JBrowse link NW_004955410 5,003,720 5,120,903 RGD:9068941
G Cd40lg CD40 ligand JBrowse link NW_004955489 8,465,571 8,477,714 RGD:9068941
G Fgf2 fibroblast growth factor 2 JBrowse link NW_004955428 17,840,554 17,894,779 RGD:9068941
G Gskip GSK3B interacting protein JBrowse link NW_004955438 18,153,564 18,174,980 RGD:9068941
G Jak2 Janus kinase 2 JBrowse link NW_004955434 9,227,897 9,341,208 RGD:9068941
G LOC102015452 chromosome unknown open reading frame, human C14orf132 JBrowse link NW_004955438 16,628,879 16,662,868 RGD:9068941
G Mpl MPL proto-oncogene, thrombopoietin receptor JBrowse link NW_004955537 2,922,156 2,937,223 RGD:9068941
G Myb MYB proto-oncogene, transcription factor JBrowse link NW_004955439 1,523,516 1,560,185 RGD:9068941
G Pdgfa platelet derived growth factor subunit A JBrowse link NW_004955460 8,328,400 8,346,755 RGD:9068941
G Pdgfb platelet derived growth factor subunit B JBrowse link NW_004955413 25,150,702 25,166,987 RGD:9068941
G Sh2b3 SH2B adaptor protein 3 JBrowse link NW_004955482 8,079,905 8,100,791 RGD:7240710
RGD:9068941
G Tcl1a T cell leukemia/lymphoma 1A JBrowse link NW_004955438 16,934,650 16,952,926 RGD:9068941
G Tgfb1 transforming growth factor beta 1 JBrowse link NW_004955555 274,405 288,441 RGD:9068941
G Thpo thrombopoietin JBrowse link NW_004955420 23,120,828 23,128,894 RGD:7240710
RGD:9068941
G Vcam1 vascular cell adhesion molecule 1 JBrowse link NW_004955435 5,390,745 5,410,025 RGD:9068941
G Vwf von Willebrand factor JBrowse link NW_004955413 3,672,470 3,825,588 RGD:9068941
familial chronic myelocytic leukemia-like syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Irf8 interferon regulatory factor 8 JBrowse link NW_004955541 973,004 988,493 RGD:9068941
Familial Myelofibrosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata1 GATA binding protein 1 JBrowse link NW_004955543 334,581 342,042 RGD:9068941
G Mpl MPL proto-oncogene, thrombopoietin receptor JBrowse link NW_004955537 2,922,156 2,937,223 RGD:9068941
G Vps45 vacuolar protein sorting 45 homolog JBrowse link NW_004955413 615,510 680,564 RGD:9068941
juvenile myelomonocytic leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akap12 A-kinase anchoring protein 12 JBrowse link NW_004955439 10,241,298 10,262,416 RGD:9068941
G Arhgap26 Rho GTPase activating protein 26 JBrowse link NW_004955415 10,635,410 11,066,551 RGD:7240710
RGD:9068941
G Asxl1 ASXL transcriptional regulator 1 JBrowse link NW_004955422 28,662,392 28,721,896 RGD:9068941
G Cbl Cbl proto-oncogene JBrowse link NW_004955412 20,307,011 20,388,539 RGD:7240710
RGD:9068941
G Csf2 colony stimulating factor 2 JBrowse link NW_004955408 3,452,009 3,454,255 RGD:9068941
G Dnmt3a DNA methyltransferase 3 alpha JBrowse link NW_004955469 7,264,431 7,367,059 RGD:9068941
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link NW_004955491 4,215,353 4,292,229 RGD:9068941
G Flt3 fms related tyrosine kinase 3 JBrowse link NW_004955497 7,357,533 7,441,215 RGD:9068941
G Gata2 GATA binding protein 2 JBrowse link NW_004955429 15,326,551 15,334,774 RGD:9068941
G Jak3 Janus kinase 3 JBrowse link NW_004955524 3,399,895 3,412,018 RGD:9068941
G Kras KRAS proto-oncogene, GTPase JBrowse link NW_004955413 20,298,852 20,328,756 RGD:9068941
G Nf1 neurofibromin 1 JBrowse link NW_004955481 6,145,855 6,404,179 RGD:7240710
RGD:9068941
G Nras NRAS proto-oncogene, GTPase JBrowse link NW_004955435 18,001,517 18,009,105 RGD:9068941
G Ptpn11 protein tyrosine phosphatase non-receptor type 11 JBrowse link NW_004955482 8,934,734 9,031,230 RGD:7240710
RGD:9068941
G Rac2 Rac family small GTPase 2 JBrowse link NW_004955413 23,697,504 23,710,668 RGD:9068941
G Rras RAS related JBrowse link NW_004955559 1,244,658 1,248,774 RGD:9068941
G Rras2 RAS related 2 JBrowse link NW_004955414 29,482,502 29,546,102 RGD:9068941
G Runx1 RUNX family transcription factor 1 JBrowse link NW_004955407 34,108,653 34,342,657 RGD:9068941
G Setbp1 SET binding protein 1 JBrowse link NW_004955402 30,380,346 30,738,869 RGD:9068941
G Sh2b3 SH2B adaptor protein 3 JBrowse link NW_004955482 8,079,905 8,100,791 RGD:9068941
G Zrsr2 zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2 JBrowse link NW_004955519 2,377,955 2,402,446 RGD:9068941
Leukemoid Reaction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Jak3 Janus kinase 3 JBrowse link NW_004955524 3,399,895 3,412,018 RGD:9068941
multiple myeloma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) JBrowse link NW_004955474 12,365,903 12,408,715 RGD:9068941
G Alb albumin JBrowse link NW_004955447 9,327 21,212 RGD:9068941
G Apoe apolipoprotein E JBrowse link NW_004955555 1,998,170 2,002,003 RGD:9068941
G B2m beta-2-microglobulin JBrowse link NW_004955416 11,205,503 11,211,325 RGD:9068941
G Bcl2 BCL2 apoptosis regulator JBrowse link NW_004955402 46,911,125 47,084,214 RGD:9068941
G Bcl2l1 BCL2 like 1 JBrowse link NW_004955422 29,254,440 29,307,104 RGD:9068941
G Bnip3 BCL2 interacting protein 3 JBrowse link NW_004955477 9,621,812 9,630,406 RGD:9068941
G Braf B-Raf proto-oncogene, serine/threonine kinase JBrowse link NW_004955494 2,567,238 2,712,708 RGD:9068941
G Btg1 BTG anti-proliferation factor 1 JBrowse link NW_004955405 29,206,889 29,209,407 RGD:9068941
G Cbl Cbl proto-oncogene JBrowse link NW_004955412 20,307,011 20,388,539 RGD:9068941
G Cbx7 chromobox 7 JBrowse link NW_004955413 25,079,627 25,100,039 RGD:9068941
G Ccnd1 cyclin D1 JBrowse link NW_004955422 16,449,921 16,462,676 RGD:7240710
RGD:9068941
G Ccnd2 cyclin D2 JBrowse link NW_004955413 2,083,351 2,108,450 RGD:9068941
G Ccnd3 cyclin D3 JBrowse link NW_004955437 8,266,523 8,273,855 RGD:9068941
G Cd40 CD40 molecule JBrowse link NW_004955445 11,191,817 11,202,156 RGD:9068941
G Cd40lg CD40 ligand JBrowse link NW_004955489 8,465,571 8,477,714 RGD:9068941
G Cd46 CD46 molecule JBrowse link NW_004955406 43,002,817 43,034,555 RGD:9068941
G Cd86 CD86 molecule JBrowse link NW_004955427 21,375,820 21,436,767 RGD:9068941
G Cdk4 cyclin dependent kinase 4 JBrowse link NW_004955458 5,457,927 5,460,718 RGD:9068941
G Chi3l1 chitinase 3 like 1 JBrowse link NW_004955406 39,195,101 39,201,808 RGD:9068941
G Crbn cereblon JBrowse link NW_004955421 10,166,927 10,190,470 RGD:9068941
G Csf2 colony stimulating factor 2 JBrowse link NW_004955408 3,452,009 3,454,255 RGD:9068941
G Csf3 colony stimulating factor 3 JBrowse link NW_004955451 14,688,181 14,690,126 RGD:9068941
G Ctla4 cytotoxic T-lymphocyte associated protein 4 JBrowse link NW_004955457 11,028,707 11,034,898 RGD:9068941
G Eng endoglin JBrowse link NW_004955419 818,797 853,319 RGD:9068941
G Ephx1 epoxide hydrolase 1 JBrowse link NW_004955520 116,363 142,983 RGD:9068941
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link NW_004955555 2,393,510 2,430,180 RGD:9068941
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link NW_004955555 2,355,005 2,369,599 RGD:9068941
G Faslg Fas ligand JBrowse link NW_004955406 13,098,479 13,107,045 RGD:9068941
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link NW_004955514 1,030,244 1,038,590 RGD:9068941
G Fgg fibrinogen gamma chain JBrowse link NW_004955471 8,786,910 8,794,947 RGD:9068941
G Flt3lg fms related tyrosine kinase 3 ligand JBrowse link NW_004955559 1,364,056 1,371,245 RGD:9068941
G Gpx1 glutathione peroxidase 1 JBrowse link NW_004955532 1,298,336 1,298,830 RGD:9068941
G Gstp1 glutathione S-transferase pi 1 JBrowse link NW_004955422 17,914,228 17,916,918 RGD:9068941
G Hfe homeostatic iron regulator JBrowse link NW_004955483 933,269 941,070 RGD:9068941
G Hk1 hexokinase 1 JBrowse link NW_004955437 21,733,314 21,824,303 RGD:9068941
G Hras HRas proto-oncogene, GTPase JBrowse link NW_004955476 11,508,446 11,510,333 RGD:9068941
G Hspb1 heat shock protein family B (small) member 1 JBrowse link NW_004955844 8,094 9,565 RGD:9068941
G Icam1 intercellular adhesion molecule 1 JBrowse link NW_004955495 1,561,464 1,573,282 RGD:9068941
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 JBrowse link NW_004955457 6,851,542 6,869,452 RGD:9068941
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 JBrowse link NW_004955416 15,197,611 15,212,919 RGD:9068941
G Il10 interleukin 10 JBrowse link NW_004955406 42,307,789 42,312,255 RGD:9068941
G Il1a interleukin 1 alpha JBrowse link NW_004955470 1,527,710 1,538,418 RGD:9068941
G Il1b interleukin 1 beta JBrowse link NW_004955470 1,486,936 1,491,888 RGD:9068941
G Il1rn interleukin 1 receptor antagonist JBrowse link NW_004955470 1,145,022 1,159,413 RGD:9068941
G Il4r interleukin 4 receptor JBrowse link NW_004955493 5,546,340 5,580,745 RGD:9068941
G Il6 interleukin 6 JBrowse link NW_004955410 25,079,835 25,084,390 RGD:9068941
G Irf4 interferon regulatory factor 4 JBrowse link NW_004955465 12,497,534 12,512,529 RGD:9068941
G Kras KRAS proto-oncogene, GTPase JBrowse link NW_004955413 20,298,852 20,328,756 RGD:9068941
G Lig4 DNA ligase 4 JBrowse link NW_004955404 3,606,077 3,615,193 RGD:7240710
RGD:9068941
G LOC102010850 cytochrome P450 1A1 JBrowse link NW_004955450 3,183,958 3,189,488 RGD:9068941
G Lrrc56 leucine rich repeat containing 56 JBrowse link NW_004955476 11,493,299 11,507,022 RGD:9068941
G Maf MAF bZIP transcription factor JBrowse link NW_004955522 2,514,313 2,519,694 RGD:9068941
G Mcl1 MCL1 apoptosis regulator, BCL2 family member JBrowse link NW_004955413 238,043 243,317 RGD:9068941
G Mefv MEFV innate immuity regulator, pyrin JBrowse link NW_004955442 14,068,436 14,093,889 RGD:9068941
G Met MET proto-oncogene, receptor tyrosine kinase JBrowse link NW_004955432 22,440,671 22,519,592 RGD:9068941
G Mthfr methylenetetrahydrofolate reductase JBrowse link NW_004955486 2,096,379 2,112,240 RGD:9068941
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase JBrowse link NW_004955492 3,372,915 3,474,173 RGD:9068941
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase JBrowse link NW_004955504 5,412,290 5,435,409 RGD:9068941
G Muc1 mucin 1, cell surface associated JBrowse link NW_004955545 1,657,728 1,662,112 RGD:9068941
G Myd88 MYD88 innate immune signal transduction adaptor JBrowse link NW_004955427 25,553,589 25,557,654 RGD:9068941
G Nfkbia NFKB inhibitor alpha JBrowse link NW_004955409 25,691,673 25,695,151 RGD:9068941
G Notch2 notch receptor 2 JBrowse link NW_004955568 1,660,357 1,812,285 RGD:9068941
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link NW_004955484 7,012,373 7,028,182 RGD:9068941
G Nras NRAS proto-oncogene, GTPase JBrowse link NW_004955435 18,001,517 18,009,105 RGD:9068941
G Nuak1 NUAK family kinase 1 JBrowse link NW_004955405 40,156,316 40,188,144 RGD:9068941
G Parp1 poly(ADP-ribose) polymerase 1 JBrowse link NW_004955489 520,875 557,609 RGD:9068941
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link NW_004955420 8,355,415 8,427,024 RGD:9068941
G Pon1 paraoxonase 1 JBrowse link NW_004955432 11,893,473 11,923,035 RGD:9068941
G Prame preferentially expressed antigen in melanoma JBrowse link NW_004955455 6,921,420 6,930,453 RGD:9068941
G Psors1c2 psoriasis susceptibility 1 candidate 2 JBrowse link NW_004955583 975,037 977,944 RGD:9068941
G Pthlh parathyroid hormone like hormone JBrowse link NW_004955505 6,834,533 6,846,909 RGD:9068941
G Ptpn11 protein tyrosine phosphatase non-receptor type 11 JBrowse link NW_004955482 8,934,734 9,031,230 RGD:9068941
G Ranbp2 RAN binding protein 2 JBrowse link NW_004955470 12,180,426 12,247,737 RGD:9068941
G Runx1 RUNX family transcription factor 1 JBrowse link NW_004955407 34,108,653 34,342,657 RGD:9068941
G Sod2 superoxide dismutase 2 JBrowse link NW_004955439 21,209,101 21,223,538 RGD:9068941
G Sparc secreted protein acidic and cysteine rich JBrowse link NW_004955408 6,100,123 6,122,460 RGD:9068941
G Spp1 secreted phosphoprotein 1 JBrowse link NW_004955474 1,914,477 1,922,025 RGD:9068941
G Tert telomerase reverse transcriptase JBrowse link NW_004955504 649,248 669,796 RGD:9068941
G Tfrc transferrin receptor JBrowse link NW_004955420 12,348,392 12,372,714 RGD:9068941
G Tgfb1 transforming growth factor beta 1 JBrowse link NW_004955555 274,405 288,441 RGD:9068941
G Tnf tumor necrosis factor JBrowse link NW_004955437 117,267 119,899 RGD:9068941
G Tnfrsf13b TNF receptor superfamily member 13B JBrowse link NW_004955577 930,612 971,698 RGD:9068941
G Tnfrsf17 TNF receptor superfamily member 17 JBrowse link NW_004955442 6,626,434 6,651,193 RGD:9068941
G Tp53 tumor protein p53 JBrowse link NW_004955467 9,241,391 9,256,716 RGD:9068941
G Tyms thymidylate synthetase JBrowse link NW_004955402 9,295,862 9,304,952 RGD:9068941
G Ulk4 unc-51 like kinase 4 JBrowse link NW_004955420 28,633,011 29,031,161 RGD:9068941
G Vegfa vascular endothelial growth factor A JBrowse link NW_004955437 9,527,445 9,541,908 RGD:9068941
G Xpo5 exportin 5 JBrowse link NW_004955437 9,351,045 9,392,396 RGD:9068941
G Xrcc4 X-ray repair cross complementing 4 JBrowse link NW_004955418 27,174,510 27,426,245 RGD:9068941
G Xrcc5 X-ray repair cross complementing 5 JBrowse link NW_004955453 16,967,453 17,054,634 RGD:9068941
myelodysplastic/myeloproliferative neoplasm term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddx41 DEAD-box helicase 41 JBrowse link NW_004955408 29,748,091 29,753,610 RGD:9068941
G Dido1 death inducer-obliterator 1 JBrowse link NW_004955528 1,153,181 1,207,346 RGD:9068941
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link NW_004955491 4,215,353 4,292,229 RGD:9068941
myelofibrosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asxl1 ASXL transcriptional regulator 1 JBrowse link NW_004955422 28,662,392 28,721,896 RGD:9068941
G Atg2b autophagy related 2B JBrowse link NW_004955438 18,080,641 18,153,490 RGD:9068941
G Bdkrb1 bradykinin receptor B1 JBrowse link NW_004955438 16,500,219 16,505,394 RGD:9068941
G Bdkrb2 bradykinin receptor B2 JBrowse link NW_004955438 16,514,300 16,537,160 RGD:9068941
G Calr calreticulin JBrowse link NW_004955415 31,985,147 31,989,372 RGD:7240710
RGD:9068941
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link NW_004955555 2,393,510 2,430,180 RGD:9068941
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link NW_004955555 2,355,005 2,369,599 RGD:9068941
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link NW_004955491 4,215,353 4,292,229 RGD:9068941
G Flt3 fms related tyrosine kinase 3 JBrowse link NW_004955497 7,357,533 7,441,215 RGD:9068941
G Flt3lg fms related tyrosine kinase 3 ligand JBrowse link NW_004955559 1,364,056 1,371,245 RGD:9068941
G Gata1 GATA binding protein 1 JBrowse link NW_004955543 334,581 342,042 RGD:9068941
G Gskip GSK3B interacting protein JBrowse link NW_004955438 18,153,564 18,174,980 RGD:9068941
G Hfe homeostatic iron regulator JBrowse link NW_004955483 933,269 941,070 RGD:9068941
G Insl6 insulin like 6 JBrowse link NW_004955434 9,349,033 9,355,817 RGD:9068941
G Jak2 Janus kinase 2 JBrowse link NW_004955434 9,227,897 9,341,208 RGD:7240710
RGD:9068941
G LOC102015452 chromosome unknown open reading frame, human C14orf132 JBrowse link NW_004955438 16,628,879 16,662,868 RGD:9068941
G Mpl MPL proto-oncogene, thrombopoietin receptor JBrowse link NW_004955537 2,922,156 2,937,223 RGD:7240710
RGD:9068941
G Myb MYB proto-oncogene, transcription factor JBrowse link NW_004955439 1,523,516 1,560,185 RGD:9068941
G Ncor2 nuclear receptor corepressor 2 JBrowse link NW_004955482 4,927,482 5,031,848 RGD:9068941
G Sh2b3 SH2B adaptor protein 3 JBrowse link NW_004955482 8,079,905 8,100,791 RGD:7240710
RGD:9068941
G Tcl1a T cell leukemia/lymphoma 1A JBrowse link NW_004955438 16,934,650 16,952,926 RGD:9068941
G Tgfb1 transforming growth factor beta 1 JBrowse link NW_004955555 274,405 288,441 RGD:9068941
G Tp53 tumor protein p53 JBrowse link NW_004955467 9,241,391 9,256,716 RGD:9068941
Myeloid Leukemia, Accelerated Phase term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmi1 BMI1 proto-oncogene, polycomb ring finger JBrowse link NW_004955429 6,548,586 6,553,730 RGD:9068941
Myeloid Leukemia, Chronic-Phase term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link NW_004955513 652,048 799,182 RGD:9068941
G Bcr BCR activator of RhoGEF and GTPase JBrowse link NW_004955455 7,598,794 7,727,386 RGD:9068941
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link NW_004955555 2,393,510 2,430,180 RGD:9068941
G Gfi1 growth factor independent 1 transcriptional repressor JBrowse link NW_004955423 2,024,084 2,032,530 RGD:9068941
G Gfi1b growth factor independent 1B transcriptional repressor JBrowse link NW_004955513 2,273,267 2,281,850 RGD:9068941
myeloproliferative neoplasm term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Csf3r colony stimulating factor 3 receptor JBrowse link NW_004955452 14,409,484 14,425,818 RGD:9068941
G Ddx41 DEAD-box helicase 41 JBrowse link NW_004955408 29,748,091 29,753,610 RGD:9068941
G Etv6 ETS variant 6 JBrowse link NW_004955413 8,698,412 8,912,011 RGD:9068941
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link NW_004955514 1,030,244 1,038,590 RGD:9068941
G Insl6 insulin like 6 JBrowse link NW_004955434 9,349,033 9,355,817 RGD:9068941
G Jak2 Janus kinase 2 JBrowse link NW_004955434 9,227,897 9,341,208 RGD:9068941
G Jak3 Janus kinase 3 JBrowse link NW_004955524 3,399,895 3,412,018 RGD:9068941
G Kit KIT proto-oncogene, receptor tyrosine kinase JBrowse link NW_004955447 16,149,014 16,226,151 RGD:9068941
G Mpl MPL proto-oncogene, thrombopoietin receptor JBrowse link NW_004955537 2,922,156 2,937,223 RGD:9068941
G Pdgfrb platelet derived growth factor receptor beta JBrowse link NW_004955415 4,365,848 4,403,317 RGD:9068941
G Tet2 tet methylcytosine dioxygenase 2 JBrowse link NW_004955496 3,885,684 3,963,056 RGD:9068941
Noonan Syndrome-Like Disorder with or without Juvenile Myelomonocytic Leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbl Cbl proto-oncogene JBrowse link NW_004955412 20,307,011 20,388,539 RGD:7240710
RGD:9068941
G Ptpn11 protein tyrosine phosphatase non-receptor type 11 JBrowse link NW_004955482 8,934,734 9,031,230 RGD:9068941
plasmacytic leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd40 CD40 molecule JBrowse link NW_004955445 11,191,817 11,202,156 RGD:9068941
G Tert telomerase reverse transcriptase JBrowse link NW_004955504 649,248 669,796 RGD:9068941
polycythemia vera term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2l1 BCL2 like 1 JBrowse link NW_004955422 29,254,440 29,307,104 RGD:9068941
G Cd36 CD36 molecule JBrowse link NW_004955410 5,003,720 5,120,903 RGD:9068941
G Epor erythropoietin receptor JBrowse link NW_004955495 2,293,587 2,299,302 RGD:9068941
G Gsr glutathione-disulfide reductase JBrowse link NW_004955463 7,130,459 7,153,631 RGD:9068941
G Hbb hemoglobin subunit beta JBrowse link NW_004955414 21,188,012 21,189,363 RGD:9068941
G Hfe homeostatic iron regulator JBrowse link NW_004955483 933,269 941,070 RGD:9068941
G Insl6 insulin like 6 JBrowse link NW_004955434 9,349,033 9,355,817 RGD:9068941
G Jak1 Janus kinase 1 JBrowse link NW_004955423 25,501,989 25,581,826 RGD:9068941
G Jak2 Janus kinase 2 JBrowse link NW_004955434 9,227,897 9,341,208 RGD:7240710
RGD:9068941
Thrombocythemia 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mpl MPL proto-oncogene, thrombopoietin receptor JBrowse link NW_004955537 2,922,156 2,937,223 RGD:7240710
RGD:9068941
Thrombocythemia 3 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Insl6 insulin like 6 JBrowse link NW_004955434 9,349,033 9,355,817 RGD:9068941
G Jak2 Janus kinase 2 JBrowse link NW_004955434 9,227,897 9,341,208 RGD:7240710
RGD:9068941
Thrombocytopenia, Anemia, and Myelofibrosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mpig6b megakaryocyte and platelet inhibitory receptor G6b JBrowse link NW_004955437 259,780 264,549 RGD:7240710
RGD:9068941
thrombocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Calr calreticulin JBrowse link NW_004955415 31,985,147 31,989,372 RGD:9068941
G Cpb2 carboxypeptidase B2 JBrowse link NW_004955518 3,740,348 3,803,540 RGD:9068941
G Epor erythropoietin receptor JBrowse link NW_004955495 2,293,587 2,299,302 RGD:9068941
G Il1b interleukin 1 beta JBrowse link NW_004955470 1,486,936 1,491,888 RGD:9068941
G Jak2 Janus kinase 2 JBrowse link NW_004955434 9,227,897 9,341,208 RGD:9068941
G Mpl MPL proto-oncogene, thrombopoietin receptor JBrowse link NW_004955537 2,922,156 2,937,223 RGD:9068941
G Thpo thrombopoietin JBrowse link NW_004955420 23,120,828 23,128,894 RGD:9068941
Thrombocytosis, Benign Familial Microcytic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mpl MPL proto-oncogene, thrombopoietin receptor JBrowse link NW_004955537 2,922,156 2,937,223 RGD:9068941
transient myeloproliferative syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata1 GATA binding protein 1 JBrowse link NW_004955543 334,581 342,042 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 11208
    disease of anatomical entity 10874
      hematopoietic system disease 1230
        bone marrow disease 360
          myeloid neoplasm 201
            Acute Erythroblastic Leukemia + 13
            Chronic Myeloproliferative Disorder with Eosinophilia 1
            Leukemoid Reaction + 2
            Myeloproliferative Disease, Autosomal Recessive 0
            chronic myeloid leukemia + 72
            chronic neutrophilic leukemia 1
            multiple myeloma + 91
            myelodysplastic/myeloproliferative neoplasm + 29
            myelofibrosis + 25
            myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1 + 0
            myelophthisic anemia 0
            myeloproliferative neoplasm + 36
            thrombocytosis + 24
Path 2
Term Annotations click to browse term
  disease 11208
    disease of anatomical entity 10874
      Hemic and Lymphatic Diseases 1473
        hematopoietic system disease 1230
          Hematologic Neoplasms 695
            hematologic cancer 695
              bone marrow cancer 257
                myeloid neoplasm 201
                  Acute Erythroblastic Leukemia + 13
                  Chronic Myeloproliferative Disorder with Eosinophilia 1
                  Leukemoid Reaction + 2
                  Myeloproliferative Disease, Autosomal Recessive 0
                  chronic myeloid leukemia + 72
                  chronic neutrophilic leukemia 1
                  multiple myeloma + 91
                  myelodysplastic/myeloproliferative neoplasm + 29
                  myelofibrosis + 25
                  myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1 + 0
                  myelophthisic anemia 0
                  myeloproliferative neoplasm + 36
                  thrombocytosis + 24
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.