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ONTOLOGY REPORT - ANNOTATIONS


Term:myeloid neoplasm
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Accession:DOID:0070004 term browser browse the term
Definition:Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE.
Synonyms:exact_synonym: Myeloproliferative Disorder;   Myeloproliferative Disorders;   myeloma
 primary_id: MESH:D009196;   RDO:0004832
For additional species annotation, visit the Alliance of Genome Resources.


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myeloid neoplasm term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) JBrowse link 2 30,661,333 30,691,283 RGD:9068941
G ALOX12 arachidonate 12-lipoxygenase, 12S type JBrowse link 5 32,026,193 32,038,698 RGD:9068941
G ATG2B autophagy related 2B JBrowse link 8 65,039,960 65,110,811 RGD:9068941
G BCR BCR activator of RhoGEF and GTPase JBrowse link 26 27,856,280 27,980,923 RGD:9068941
G CBL Cbl proto-oncogene JBrowse link 5 14,600,409 14,676,974 RGD:9068941
G CD36 CD36 molecule JBrowse link 18 20,299,808 20,375,856 RGD:9068941
G CSF1R colony stimulating factor 1 receptor JBrowse link 4 58,980,699 59,010,683 RGD:9068941
G EGR1 early growth response 1 JBrowse link 11 26,046,195 26,049,806 RGD:9068941
G ETV6 ETS variant transcription factor 6 JBrowse link 27 34,351,206 34,587,060 RGD:9068941
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 16 1,926,443 1,991,995 RGD:9068941
G F3 coagulation factor III, tissue factor JBrowse link 6 54,709,581 54,720,603 RGD:9068941
G FGFR1 fibroblast growth factor receptor 1 JBrowse link 16 27,029,902 27,080,514 RGD:9068941
G FGFR1OP2 FGFR1 oncogene partner 2 JBrowse link 27 20,672,166 20,704,530 RGD:9068941
G FGFR3 fibroblast growth factor receptor 3 JBrowse link 3 62,309,128 62,318,932 RGD:9068941
G FLT3 fms related tyrosine kinase 3 JBrowse link 25 11,551,372 11,670,891 RGD:9068941
G GFI1 growth factor independent 1 transcriptional repressor JBrowse link 6 56,473,032 56,484,422 RGD:9068941
G GFI1B growth factor independent 1B transcriptional repressor JBrowse link 9 51,380,697 51,394,679 RGD:9068941
G GPX1 glutathione peroxidase 1 JBrowse link 20 39,889,165 39,890,253 RGD:9068941
G GSKIP GSK3B interacting protein JBrowse link 8 65,110,659 65,131,205 RGD:9068941
G HSPA5 heat shock protein family A (Hsp70) member 5 JBrowse link 9 57,850,870 57,855,607 RGD:9068941
G INSL6 insulin like 6 JBrowse link 1 93,457,854 93,474,777 RGD:9068941
G IRF4 interferon regulatory factor 4 JBrowse link 35 760,367 782,314 RGD:9068941
G IRF8 interferon regulatory factor 8 JBrowse link 5 66,789,264 66,812,477 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 1 93,321,055 93,438,898 RGD:9068941
G KRAS KRAS proto-oncogene, GTPase JBrowse link 27 22,261,753 22,296,704 RGD:9068941
G MECOM MDS1 and EVI1 complex locus JBrowse link 34 33,747,495 34,299,389 RGD:9068941
G MTHFR methylenetetrahydrofolate reductase JBrowse link 2 84,445,526 84,457,435 RGD:9068941
G NPM1 nucleophosmin 1 JBrowse link 4 40,756,464 40,770,174 RGD:9068941
G NQO1 NAD(P)H quinone dehydrogenase 1 JBrowse link 5 79,979,593 79,990,875 RGD:9068941
G NQO2 N-ribosyldihydronicotinamide:quinone reductase 2 JBrowse link 35 3,294,776 3,315,438 RGD:9068941
G NRAS NRAS proto-oncogene, GTPase JBrowse link 17 52,411,733 52,418,788 RGD:9068941
G RUNX1 RUNX family transcription factor 1 JBrowse link 31 30,170,859 30,420,344 RGD:9068941
G ZMYM2 zinc finger MYM-type containing 2 JBrowse link 25 18,040,081 18,158,241 RGD:9068941
Acute Erythroblastic Leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase JBrowse link 17 21,198,839 21,221,897 RGD:9068941
G DHODH dihydroorotate dehydrogenase (quinone) JBrowse link 5 77,756,411 77,766,207 RGD:9068941
G UMPS uridine monophosphate synthetase JBrowse link 33 27,754,592 27,782,517 RGD:9068941
Acute Erythroleukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DDX41 DEAD-box helicase 41 JBrowse link 4 35,854,382 35,859,853 RGD:9068941
G ERBB3 erb-b2 receptor tyrosine kinase 3 JBrowse link 10 406,856 424,746 RGD:9068941
G FLT3 fms related tyrosine kinase 3 JBrowse link 25 11,551,372 11,670,891 RGD:9068941
G GFI1B growth factor independent 1B transcriptional repressor JBrowse link 9 51,380,697 51,394,679 RGD:9068941
G HOXB9 homeobox B9 JBrowse link 9 24,884,101 24,889,904 RGD:9068941
G KMT2A lysine methyltransferase 2A JBrowse link 5 15,212,559 15,302,825 RGD:9068941
G NPM1 nucleophosmin 1 JBrowse link 4 40,756,464 40,770,174 RGD:9068941
G NUP98 nucleoporin 98 JBrowse link 21 26,231,585 26,348,019 RGD:9068941
G RB1 RB transcriptional corepressor 1 JBrowse link 22 3,061,621 3,204,625 RGD:9068941
G TP53 tumor protein p53 JBrowse link 5 32,561,406 32,565,149 RGD:9068941
atypical chronic myeloid leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FGFR1 fibroblast growth factor receptor 1 JBrowse link 16 27,029,902 27,080,514 RGD:9068941
G SETBP1 SET binding protein 1 JBrowse link 7 46,020,892 46,378,867 RGD:9068941
Blast Crisis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AICDA activation induced cytidine deaminase JBrowse link 27 37,064,107 37,073,791 RGD:9068941
G BCR BCR activator of RhoGEF and GTPase JBrowse link 26 27,856,280 27,980,923 RGD:9068941
G ESR2 estrogen receptor 2 JBrowse link 8 38,645,917 38,715,347 RGD:9068941
G HMOX1 heme oxygenase 1 JBrowse link 10 28,744,404 28,751,544 RGD:9068941
G MIR150 microRNA mir-150 JBrowse link 1 106,998,756 106,998,812 RGD:9068941
G TCN2 transcobalamin 2 JBrowse link 26 23,693,664 23,710,342 RGD:9068941
chronic myeloid leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCB1 ATP binding cassette subfamily B member 1 JBrowse link 14 13,644,891 13,852,829 RGD:9068941
G ABCC2 ATP binding cassette subfamily C member 2 JBrowse link 28 12,670,885 12,740,124 RGD:9068941
G ABCG2 ATP binding cassette subfamily G member 2 JBrowse link 32 11,443,778 11,517,674 RGD:9068941
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 9 53,118,462 53,262,092 RGD:7240710
RGD:9068941
G ACE angiotensin I converting enzyme JBrowse link 9 11,497,182 11,516,362 RGD:9068941
G AGT angiotensinogen JBrowse link 4 8,681,192 8,694,059 RGD:9068941
G AKT1 AKT serine/threonine kinase 1 JBrowse link 8 72,317,399 72,335,686 RGD:9068941
G ALOX5 arachidonate 5-lipoxygenase JBrowse link 28 2,170,920 2,218,765 RGD:9068941
G ARNTL aryl hydrocarbon receptor nuclear translocator like JBrowse link 21 36,254,235 36,323,915 RGD:9068941
G B9D2 B9 domain containing 2 JBrowse link 1 112,621,832 112,627,726 RGD:9068941
G BCL2L1 BCL2 like 1 JBrowse link 24 21,145,214 21,209,425 RGD:9068941
G BCR BCR activator of RhoGEF and GTPase JBrowse link 26 27,856,280 27,980,923 RGD:7240710
RGD:9068941
G BIRC5 baculoviral IAP repeat containing 5 JBrowse link 9 2,930,308 2,959,307 RGD:9068941
G BRAF B-Raf proto-oncogene, serine/threonine kinase JBrowse link 16 8,222,909 8,318,179 RGD:9068941
G CA9 carbonic anhydrase 9 JBrowse link 11 52,205,619 52,211,281 RGD:9068941
G CD36 CD36 molecule JBrowse link 18 20,299,808 20,375,856 RGD:9068941
G CD40 CD40 molecule JBrowse link 24 33,352,992 33,383,488 RGD:9068941
G CDKN1B cyclin dependent kinase inhibitor 1B JBrowse link 27 33,609,154 33,613,558 RGD:9068941
G CDKN2A cyclin dependent kinase inhibitor 2A JBrowse link 11 41,223,316 41,226,056 RGD:9068941
G CHORDC1 cysteine and histidine rich domain containing 1 JBrowse link 21 10,129,812 10,152,416 RGD:9068941
G CRKL CRK like proto-oncogene, adaptor protein JBrowse link 26 30,542,276 30,582,479 RGD:9068941
G CRY1 cryptochrome circadian regulator 1 JBrowse link 10 31,681,098 31,792,995 RGD:9068941
G CRY2 cryptochrome circadian regulator 2 JBrowse link 18 43,538,335 43,573,651 RGD:9068941
G CSF3R colony stimulating factor 3 receptor JBrowse link 15 5,818,985 5,832,455 RGD:9068941
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 JBrowse link 30 37,793,277 37,799,535 RGD:9068941
G CYP3A26 cytochrome P450 3A26 JBrowse link 6 9,777,663 9,815,345 RGD:9068941
G DNMT1 DNA methyltransferase 1 JBrowse link 20 50,872,213 50,928,352 RGD:9068941
G DNMT3A DNA methyltransferase 3 alpha JBrowse link 17 19,489,524 19,563,074 RGD:9068941
G DNMT3B DNA methyltransferase 3 beta JBrowse link 24 22,096,386 22,123,378 RGD:9068941
G E2F1 E2F transcription factor 1 JBrowse link 24 22,895,149 22,904,689 RGD:9068941
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 1 110,173,781 110,191,612 RGD:9068941
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 16 1,926,443 1,991,995 RGD:9068941
G FAS Fas cell surface death receptor JBrowse link 26 38,738,811 38,763,298 RGD:9068941
G FASLG Fas ligand JBrowse link 7 26,335,837 26,344,224 RGD:9068941
G GAB2 GRB2 associated binding protein 2 JBrowse link 21 20,414,903 20,605,807 RGD:9068941
G GPX1 glutathione peroxidase 1 JBrowse link 20 39,889,165 39,890,253 RGD:9068941
G GSTP1 glutathione S-transferase pi 1 JBrowse link 18 49,905,161 49,908,182 RGD:9068941
G HMMR hyaluronan mediated motility receptor JBrowse link 4 47,743,576 47,786,982 RGD:9068941
G HMOX1 heme oxygenase 1 JBrowse link 10 28,744,404 28,751,544 RGD:9068941
G HSPA5 heat shock protein family A (Hsp70) member 5 JBrowse link 9 57,850,870 57,855,607 RGD:9068941
G IL10 interleukin 10 JBrowse link 7 5,933,285 5,937,057 RGD:9068941
G IL1B interleukin 1 beta JBrowse link 17 37,019,329 37,033,388 RGD:9068941
G IL1RN interleukin 1 receptor antagonist JBrowse link 17 37,236,690 37,250,424 RGD:9068941
G INSL6 insulin like 6 JBrowse link 1 93,457,854 93,474,777 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 1 93,321,055 93,438,898 RGD:9068941
G KIT KIT proto-oncogene, receptor tyrosine kinase JBrowse link 13 47,108,442 47,190,935 RGD:9068941
G LOC100856137 HLA class II histocompatibility antigen, DQ beta 2 chain JBrowse link 12 2,244,820 2,250,822 RGD:9068941
G MAPK14 mitogen-activated protein kinase 14 JBrowse link 12 5,145,647 5,221,558 RGD:9068941
G MDM2 MDM2 proto-oncogene JBrowse link 10 10,936,288 10,963,118 RGD:9068941
G MIR150 microRNA mir-150 JBrowse link 1 106,998,756 106,998,812 RGD:9068941
G MLF1 myeloid leukemia factor 1 JBrowse link 23 51,918,504 51,935,164 RGD:9068941
G MTHFR methylenetetrahydrofolate reductase JBrowse link 2 84,445,526 84,457,435 RGD:9068941
G NCSTN nicastrin JBrowse link 38 21,878,071 21,891,362 RGD:9068941
G NPM1 nucleophosmin 1 JBrowse link 4 40,756,464 40,770,174 RGD:9068941
G NQO1 NAD(P)H quinone dehydrogenase 1 JBrowse link 5 79,979,593 79,990,875 RGD:9068941
G NRAS NRAS proto-oncogene, GTPase JBrowse link 17 52,411,733 52,418,788 RGD:9068941
G PECAM1 platelet and endothelial cell adhesion molecule 1 JBrowse link 9 12,166,124 12,219,553 RGD:9068941
G PER1 period circadian regulator 1 JBrowse link 5 32,957,517 32,972,368 RGD:9068941
G PER2 period circadian regulator 2 JBrowse link 25 48,716,499 48,761,617 RGD:9068941
G PER3 period circadian regulator 3 JBrowse link 5 61,445,580 61,499,393 RGD:9068941
G PRAME preferentially expressed antigen in melanoma JBrowse link 26 27,124,901 27,137,772 RGD:9068941
G SETBP1 SET binding protein 1 JBrowse link 7 46,020,892 46,378,867 RGD:9068941
G SH2B3 SH2B adaptor protein 3 JBrowse link 26 9,033,851 9,073,095 RGD:9068941
G SIPA1 signal-induced proliferation-associated 1 JBrowse link 18 51,560,551 51,571,291 RGD:9068941
G SMAD4 SMAD family member 4 JBrowse link 1 23,875,989 23,930,027 RGD:9068941
G SRSF1 serine and arginine rich splicing factor 1 JBrowse link 9 32,692,517 32,696,325 RGD:9068941
G TERT telomerase reverse transcriptase JBrowse link 34 11,288,622 11,307,790 RGD:9068941
G VEGFA vascular endothelial growth factor A JBrowse link 12 12,209,032 12,224,978 RGD:9068941
G WT1 WT1 transcription factor JBrowse link 18 35,099,660 35,148,767 RGD:9068941
G XRCC1 X-ray repair cross complementing 1 JBrowse link 1 111,548,719 111,571,816 RGD:9068941
chronic myelomonocytic leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ASXL1 ASXL transcriptional regulator 1 JBrowse link 24 21,725,126 21,804,745 RGD:9068941
G CDKN2B cyclin dependent kinase inhibitor 2B JBrowse link 11 41,259,627 41,264,832 RGD:9068941
G CSF3R colony stimulating factor 3 receptor JBrowse link 15 5,818,985 5,832,455 RGD:9068941
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 16 1,926,443 1,991,995 RGD:9068941
G KDM6A lysine demethylase 6A JBrowse link X 38,745,854 38,964,029 RGD:9068941
G NRAS NRAS proto-oncogene, GTPase JBrowse link 17 52,411,733 52,418,788 RGD:9068941
G TET2 tet methylcytosine dioxygenase 2 JBrowse link 32 26,021,745 26,145,109 RGD:9068941
Chronic Myeloproliferative Disorder with Eosinophilia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFRB platelet derived growth factor receptor beta JBrowse link 4 58,925,922 58,963,639 RGD:7240710
RGD:9068941
chronic neutrophilic leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CSF3R colony stimulating factor 3 receptor JBrowse link 15 5,818,985 5,832,455 RGD:9068941
essential thrombocythemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATG2B autophagy related 2B JBrowse link 8 65,039,960 65,110,811 RGD:9068941
G B9D2 B9 domain containing 2 JBrowse link 1 112,621,832 112,627,726 RGD:9068941
G BDKRB1 bradykinin receptor B1 JBrowse link 8 65,017,655 65,028,899 RGD:9068941
G BDKRB2 bradykinin receptor B2 JBrowse link 8 64,974,588 65,005,682 RGD:9068941
G C8H14orf132 chromosome 8 C14orf132 homolog JBrowse link 8 64,813,713 64,861,449 RGD:9068941
G CALR calreticulin JBrowse link 20 49,251,390 49,255,291 RGD:7240710
RGD:9068941
G CD36 CD36 molecule JBrowse link 18 20,299,808 20,375,856 RGD:9068941
G CD40LG CD40 ligand JBrowse link X 107,001,421 107,023,007 RGD:9068941
G ELANE elastase, neutrophil expressed JBrowse link 20 57,789,044 57,790,932 RGD:9068941
G FGF2 fibroblast growth factor 2 JBrowse link 19 17,403,288 17,463,143 RGD:9068941
G GSKIP GSK3B interacting protein JBrowse link 8 65,110,659 65,131,205 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 1 93,321,055 93,438,898 RGD:9068941
G MPL MPL proto-oncogene, thrombopoietin receptor JBrowse link 15 16,815,102 16,825,321 RGD:9068941
G MYB MYB proto-oncogene, transcription factor JBrowse link 1 27,908,309 27,991,984 RGD:9068941
G PDGFA platelet derived growth factor subunit A JBrowse link 6 16,271,082 16,293,246 RGD:9068941
G PDGFB platelet derived growth factor subunit B JBrowse link 10 25,798,877 25,819,422 RGD:9068941
G SH2B3 SH2B adaptor protein 3 JBrowse link 26 9,033,851 9,073,095 RGD:7240710
RGD:9068941
G THPO thrombopoietin JBrowse link 34 17,245,006 17,255,250 RGD:7240710
RGD:9068941
G VCAM1 vascular cell adhesion molecule 1 JBrowse link 6 49,341,669 49,359,841 RGD:9068941
G VWF von Willebrand factor JBrowse link 27 38,834,812 38,972,614 RGD:9068941
familial chronic myelocytic leukemia-like syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IRF8 interferon regulatory factor 8 JBrowse link 5 66,789,264 66,812,477 RGD:9068941
Familial Myelofibrosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GATA1 GATA binding protein 1 JBrowse link X 41,991,321 41,998,319 RGD:9068941
G MPL MPL proto-oncogene, thrombopoietin receptor JBrowse link 15 16,815,102 16,825,321 RGD:9068941
G VPS45 vacuolar protein sorting 45 homolog JBrowse link 17 59,327,781 59,402,172 RGD:9068941
juvenile myelomonocytic leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKAP12 A-kinase anchoring protein 12 JBrowse link 1 41,614,893 41,712,350 RGD:9068941
G ARHGAP26 Rho GTPase activating protein 26 JBrowse link 2 37,627,448 38,045,589 RGD:7240710
RGD:9068941
G ASXL1 ASXL transcriptional regulator 1 JBrowse link 24 21,725,126 21,804,745 RGD:9068941
G CBL Cbl proto-oncogene JBrowse link 5 14,600,409 14,676,974 RGD:7240710
RGD:9068941
G CSF2 colony stimulating factor 2 JBrowse link 11 20,342,880 20,346,959 RGD:9068941
G DNMT3A DNA methyltransferase 3 alpha JBrowse link 17 19,489,524 19,563,074 RGD:9068941
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 16 1,926,443 1,991,995 RGD:9068941
G FLT3 fms related tyrosine kinase 3 JBrowse link 25 11,551,372 11,670,891 RGD:9068941
G GATA2 GATA binding protein 2 JBrowse link 20 2,472,251 2,488,380 RGD:9068941
G JAK3 Janus kinase 3 JBrowse link 20 45,051,135 45,068,445 RGD:9068941
G KRAS KRAS proto-oncogene, GTPase JBrowse link 27 22,261,753 22,296,704 RGD:9068941
G NF1 neurofibromin 1 JBrowse link 9 41,467,460 41,679,388 RGD:7240710
RGD:9068941
G NRAS NRAS proto-oncogene, GTPase JBrowse link 17 52,411,733 52,418,788 RGD:9068941
G PTPN11 protein tyrosine phosphatase non-receptor type 11 JBrowse link 26 9,989,218 10,072,245 RGD:7240710
RGD:9068941
G RAC2 Rac family small GTPase 2 JBrowse link 10 27,295,597 27,311,864 RGD:9068941
G RRAS RAS related JBrowse link 1 106,895,413 106,899,265 RGD:9068941
G RRAS2 RAS related 2 JBrowse link 21 37,037,576 37,119,733 RGD:9068941
G RUNX1 RUNX family transcription factor 1 JBrowse link 31 30,170,859 30,420,344 RGD:9068941
G SETBP1 SET binding protein 1 JBrowse link 7 46,020,892 46,378,867 RGD:9068941
G SH2B3 SH2B adaptor protein 3 JBrowse link 26 9,033,851 9,073,095 RGD:9068941
G ZRSR2 zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2 JBrowse link X 12,046,163 12,073,617 RGD:9068941
Leukemoid Reaction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G JAK3 Janus kinase 3 JBrowse link 20 45,051,135 45,068,445 RGD:9068941
multiple myeloma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCG2 ATP binding cassette subfamily G member 2 JBrowse link 32 11,443,778 11,517,674 RGD:9068941
G ACE angiotensin I converting enzyme JBrowse link 9 11,497,182 11,516,362 RGD:9068941
G ALB albumin JBrowse link 13 62,133,747 62,169,349 RGD:9068941
G APOE apolipoprotein E JBrowse link 1 110,525,717 110,528,534 RGD:9068941
G B2M beta-2-microglobulin JBrowse link 30 11,331,574 11,337,991 RGD:9068941
G B9D2 B9 domain containing 2 JBrowse link 1 112,621,832 112,627,726 RGD:9068941
G BCL2 BCL2 apoptosis regulator JBrowse link 1 13,733,849 13,900,653 RGD:9068941
G BCL2L1 BCL2 like 1 JBrowse link 24 21,145,214 21,209,425 RGD:9068941
G BCL2L10 BCL2 like 10 JBrowse link 30 17,824,030 17,828,115 RGD:9068941
G BNIP3 BCL2 interacting protein 3 JBrowse link 28 40,037,681 40,050,499 RGD:9068941
G BRAF B-Raf proto-oncogene, serine/threonine kinase JBrowse link 16 8,222,909 8,318,179 RGD:9068941
G BTG1 BTG anti-proliferation factor 1 JBrowse link 15 32,646,520 32,648,222 RGD:9068941
G CBL Cbl proto-oncogene JBrowse link 5 14,600,409 14,676,974 RGD:9068941
G CBX7 chromobox 7 JBrowse link 10 25,876,022 25,896,284 RGD:9068941
G CCL2 C-C motif chemokine ligand 2 JBrowse link 9 39,008,187 39,009,932 RGD:9068941
G CCND1 cyclin D1 JBrowse link 18 48,501,905 48,509,684 RGD:7240710
RGD:9068941
G CCND2 cyclin D2 JBrowse link 27 40,563,306 40,593,362 RGD:9068941
G CCND3 cyclin D3 JBrowse link 12 10,593,786 10,688,304 RGD:9068941
G CD40 CD40 molecule JBrowse link 24 33,352,992 33,383,488 RGD:9068941
G CD40LG CD40 ligand JBrowse link X 107,001,421 107,023,007 RGD:9068941
G CD86 CD86 molecule JBrowse link 33 25,256,267 25,318,855 RGD:9068941
G CDK4 cyclin dependent kinase 4 JBrowse link 10 1,812,864 1,815,815 RGD:9068941
G CDKN2A cyclin dependent kinase inhibitor 2A JBrowse link 11 41,223,316 41,226,056 RGD:9068941
G CHI3L1 chitinase 3 like 1 JBrowse link 7 25,620 32,954 RGD:9068941
G CRBN cereblon JBrowse link 20 14,240,723 14,275,617 RGD:9068941
G CSF2 colony stimulating factor 2 JBrowse link 11 20,342,880 20,346,959 RGD:9068941
G CSF3 colony stimulating factor 3 JBrowse link 9 22,529,643 22,532,326 RGD:9068941
G CTLA4 cytotoxic T-lymphocyte associated protein 4 JBrowse link 37 12,647,712 12,653,874 RGD:9068941
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 JBrowse link 30 37,793,277 37,799,535 RGD:9068941
G CYP2D15 cytochrome P450 2D JBrowse link 10 23,255,259 23,259,380 RGD:9068941
G DLA88 MHC class I DLA-88 JBrowse link 12 892,442 895,691 RGD:9068941
G ENG endoglin JBrowse link 9 55,558,246 55,590,081 RGD:9068941
G EPHX1 epoxide hydrolase 1 JBrowse link 7 38,964,319 39,004,902 RGD:9068941
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 110,130,353 110,146,660 RGD:9068941
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 1 110,173,781 110,191,612 RGD:9068941
G FASLG Fas ligand JBrowse link 7 26,335,837 26,344,224 RGD:9068941
G FGFR3 fibroblast growth factor receptor 3 JBrowse link 3 62,309,128 62,318,932 RGD:9068941
G FGG fibrinogen gamma chain JBrowse link 15 52,261,215 52,270,077 RGD:9068941
G FLT3LG fms related tyrosine kinase 3 ligand JBrowse link 1 107,015,222 107,025,181 RGD:9068941
G GPX1 glutathione peroxidase 1 JBrowse link 20 39,889,165 39,890,253 RGD:9068941
G GSTP1 glutathione S-transferase pi 1 JBrowse link 18 49,905,161 49,908,182 RGD:9068941
G HFE homeostatic iron regulator JBrowse link 35 24,031,479 24,038,922 RGD:9068941
G HK1 hexokinase 1 JBrowse link 4 20,396,761 20,516,889 RGD:9068941
G HRAS HRas proto-oncogene, GTPase JBrowse link 18 25,642,844 25,644,717 RGD:9068941
G HSPB1 heat shock protein family B (small) member 1 JBrowse link 6 7,487,164 7,488,576 RGD:9068941
G ICAM1 intercellular adhesion molecule 1 JBrowse link 20 50,818,715 50,827,914 RGD:9068941
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 JBrowse link 37 16,512,027 16,531,269 RGD:9068941
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 JBrowse link 3 53,070,462 53,077,566 RGD:9068941
G IL10 interleukin 10 JBrowse link 7 5,933,285 5,937,057 RGD:9068941
G IL1A interleukin 1 alpha JBrowse link 17 36,969,581 36,979,445 RGD:9068941
G IL1B interleukin 1 beta JBrowse link 17 37,019,329 37,033,388 RGD:9068941
G IL1RN interleukin 1 receptor antagonist JBrowse link 17 37,236,690 37,250,424 RGD:9068941
G IL4R interleukin 4 receptor JBrowse link 6 19,254,183 19,280,973 RGD:9068941
G IL6 interleukin 6 JBrowse link 14 36,474,268 36,478,519 RGD:9068941
G IRF4 interferon regulatory factor 4 JBrowse link 35 760,367 782,314 RGD:9068941
G KRAS KRAS proto-oncogene, GTPase JBrowse link 27 22,261,753 22,296,704 RGD:9068941
G LIG4 DNA ligase 4 JBrowse link 22 56,980,333 56,987,636 RGD:7240710
RGD:9068941
G LOC474539 E3 SUMO-protein ligase RanBP2 JBrowse link 10 35,088,175 35,181,248 RGD:9068941
G LOC609365 CD46 molecule, complement regulatory protein-like JBrowse link 7 6,602,762 6,646,561 RGD:9068941
G LRRC56 leucine rich repeat containing 56 JBrowse link 18 25,647,024 25,662,646 RGD:9068941
G MAF MAF bZIP transcription factor JBrowse link 5 71,965,291 71,982,903 RGD:9068941
G MCL1 MCL1 apoptosis regulator, BCL2 family member JBrowse link 17 59,759,605 59,763,111 RGD:9068941
G MEFV MEFV innate immuity regulator, pyrin JBrowse link 6 37,964,776 37,984,830 RGD:9068941
G MET MET proto-oncogene, receptor tyrosine kinase JBrowse link 14 55,599,047 55,711,626 RGD:9068941
G MIR19A microRNA mir-19a JBrowse link 22 42,478,298 42,478,355 RGD:9068941
G MIR92A-1 microRNA mir-92a-1 JBrowse link 22 42,478,714 42,478,772 RGD:9068941
G MTHFR methylenetetrahydrofolate reductase JBrowse link 2 84,445,526 84,457,435 RGD:9068941
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase JBrowse link 4 3,219,851 3,328,000 RGD:9068941
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase JBrowse link 34 6,068,572 6,119,580 RGD:9068941
G MUC1 mucin 1, cell surface associated JBrowse link 7 42,338,939 42,344,690 RGD:9068941
G MYD88 MYD88 innate immune signal transduction adaptor JBrowse link 23 7,901,578 7,905,274 RGD:9068941
G NFKBIA NFKB inhibitor alpha JBrowse link 8 14,100,203 14,103,453 RGD:9068941
G NOTCH2 notch receptor 2 JBrowse link 17 56,854,825 57,020,157 RGD:9068941
G NQO1 NAD(P)H quinone dehydrogenase 1 JBrowse link 5 79,979,593 79,990,875 RGD:9068941
G NRAS NRAS proto-oncogene, GTPase JBrowse link 17 52,411,733 52,418,788 RGD:9068941
G NUAK1 NUAK family kinase 1 JBrowse link 10 32,463,845 32,537,425 RGD:9068941
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 7 38,503,072 38,542,556 RGD:9068941
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 34 12,600,140 12,681,905 RGD:9068941
G PON1 paraoxonase 1 JBrowse link 14 20,565,620 20,600,774 RGD:9068941
G PRAME preferentially expressed antigen in melanoma JBrowse link 26 27,124,901 27,137,772 RGD:9068941
G PSORS1C2 psoriasis susceptibility 1 candidate 2 JBrowse link 12 837,986 840,490 RGD:9068941
G PTHLH parathyroid hormone like hormone JBrowse link 27 19,781,557 19,795,078 RGD:9068941
G PTPN11 protein tyrosine phosphatase non-receptor type 11 JBrowse link 26 9,989,218 10,072,245 RGD:9068941
G RUNX1 RUNX family transcription factor 1 JBrowse link 31 30,170,859 30,420,344 RGD:9068941
G SOD2 superoxide dismutase 2 JBrowse link 1 48,943,472 48,955,158 RGD:9068941
G SPARC secreted protein acidic and cysteine rich JBrowse link 4 57,659,541 57,682,147 RGD:9068941
G SPP1 secreted phosphoprotein 1 JBrowse link 32 11,354,070 11,362,325 RGD:9068941
G TERT telomerase reverse transcriptase JBrowse link 34 11,288,622 11,307,790 RGD:9068941
G TFRC transferrin receptor JBrowse link 33 29,206,024 29,237,221 RGD:9068941
G TNF tumor necrosis factor JBrowse link 12 1,074,561 1,076,425 RGD:9068941
G TNFRSF13B TNF receptor superfamily member 13B JBrowse link 5 42,448,976 42,483,792 RGD:9068941
G TNFRSF17 TNF receptor superfamily member 17 JBrowse link 6 30,842,269 30,846,124 RGD:9068941
G TP53 tumor protein p53 JBrowse link 5 32,561,406 32,565,149 RGD:9068941
G TYMS thymidylate synthetase JBrowse link 7 67,487,927 67,497,747 RGD:9068941
G ULK4 unc-51 like kinase 4 JBrowse link 23 10,578,391 11,176,543 RGD:9068941
G VEGFA vascular endothelial growth factor A JBrowse link 12 12,209,032 12,224,978 RGD:9068941
G XPO5 exportin 5 JBrowse link 12 11,983,071 12,034,441 RGD:9068941
G XRCC4 X-ray repair cross complementing 4 JBrowse link 3 24,316,598 24,547,463 RGD:9068941
G XRCC5 X-ray repair cross complementing 5 JBrowse link 37 23,095,769 23,185,680 RGD:9068941
myelodysplastic/myeloproliferative neoplasm term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DDX41 DEAD-box helicase 41 JBrowse link 4 35,854,382 35,859,853 RGD:9068941
G DIDO1 death inducer-obliterator 1 JBrowse link 24 46,691,117 46,735,117 RGD:9068941
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 16 1,926,443 1,991,995 RGD:9068941
myelofibrosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ASXL1 ASXL transcriptional regulator 1 JBrowse link 24 21,725,126 21,804,745 RGD:9068941
G ATG2B autophagy related 2B JBrowse link 8 65,039,960 65,110,811 RGD:9068941
G B9D2 B9 domain containing 2 JBrowse link 1 112,621,832 112,627,726 RGD:9068941
G BDKRB1 bradykinin receptor B1 JBrowse link 8 65,017,655 65,028,899 RGD:9068941
G BDKRB2 bradykinin receptor B2 JBrowse link 8 64,974,588 65,005,682 RGD:9068941
G C8H14orf132 chromosome 8 C14orf132 homolog JBrowse link 8 64,813,713 64,861,449 RGD:9068941
G CALR calreticulin JBrowse link 20 49,251,390 49,255,291 RGD:7240710
RGD:9068941
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 110,130,353 110,146,660 RGD:9068941
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 1 110,173,781 110,191,612 RGD:9068941
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 16 1,926,443 1,991,995 RGD:9068941
G FLT3 fms related tyrosine kinase 3 JBrowse link 25 11,551,372 11,670,891 RGD:9068941
G FLT3LG fms related tyrosine kinase 3 ligand JBrowse link 1 107,015,222 107,025,181 RGD:9068941
G GATA1 GATA binding protein 1 JBrowse link X 41,991,321 41,998,319 RGD:9068941
G GSKIP GSK3B interacting protein JBrowse link 8 65,110,659 65,131,205 RGD:9068941
G HFE homeostatic iron regulator JBrowse link 35 24,031,479 24,038,922 RGD:9068941
G INSL6 insulin like 6 JBrowse link 1 93,457,854 93,474,777 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 1 93,321,055 93,438,898 RGD:7240710
RGD:9068941
G MPL MPL proto-oncogene, thrombopoietin receptor JBrowse link 15 16,815,102 16,825,321 RGD:7240710
RGD:9068941
G MYB MYB proto-oncogene, transcription factor JBrowse link 1 27,908,309 27,991,984 RGD:9068941
G NCOR2 nuclear receptor corepressor 2 JBrowse link 26 5,352,670 5,493,741 RGD:9068941
G SH2B3 SH2B adaptor protein 3 JBrowse link 26 9,033,851 9,073,095 RGD:7240710
RGD:9068941
G TP53 tumor protein p53 JBrowse link 5 32,561,406 32,565,149 RGD:9068941
Myeloid Leukemia, Accelerated Phase term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BMI1 BMI1 proto-oncogene, polycomb ring finger JBrowse link 2 10,818,232 10,828,473 RGD:9068941
G MIR150 microRNA mir-150 JBrowse link 1 106,998,756 106,998,812 RGD:9068941
Myeloid Leukemia, Chronic-Phase term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 9 53,118,462 53,262,092 RGD:9068941
G BCR BCR activator of RhoGEF and GTPase JBrowse link 26 27,856,280 27,980,923 RGD:9068941
G CYP3A26 cytochrome P450 3A26 JBrowse link 6 9,777,663 9,815,345 RGD:9068941
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 110,130,353 110,146,660 RGD:9068941
G GFI1 growth factor independent 1 transcriptional repressor JBrowse link 6 56,473,032 56,484,422 RGD:9068941
G GFI1B growth factor independent 1B transcriptional repressor JBrowse link 9 51,380,697 51,394,679 RGD:9068941
myeloproliferative neoplasm term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CSF3R colony stimulating factor 3 receptor JBrowse link 15 5,818,985 5,832,455 RGD:9068941
G DDX41 DEAD-box helicase 41 JBrowse link 4 35,854,382 35,859,853 RGD:9068941
G ETV6 ETS variant transcription factor 6 JBrowse link 27 34,351,206 34,587,060 RGD:9068941
G FGFR3 fibroblast growth factor receptor 3 JBrowse link 3 62,309,128 62,318,932 RGD:9068941
G INSL6 insulin like 6 JBrowse link 1 93,457,854 93,474,777 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 1 93,321,055 93,438,898 RGD:9068941
G JAK3 Janus kinase 3 JBrowse link 20 45,051,135 45,068,445 RGD:9068941
G KIT KIT proto-oncogene, receptor tyrosine kinase JBrowse link 13 47,108,442 47,190,935 RGD:9068941
G MPL MPL proto-oncogene, thrombopoietin receptor JBrowse link 15 16,815,102 16,825,321 RGD:9068941
G PDGFRB platelet derived growth factor receptor beta JBrowse link 4 58,925,922 58,963,639 RGD:9068941
G TET2 tet methylcytosine dioxygenase 2 JBrowse link 32 26,021,745 26,145,109 RGD:9068941
Noonan Syndrome-Like Disorder with or without Juvenile Myelomonocytic Leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CBL Cbl proto-oncogene JBrowse link 5 14,600,409 14,676,974 RGD:7240710
RGD:9068941
G PTPN11 protein tyrosine phosphatase non-receptor type 11 JBrowse link 26 9,989,218 10,072,245 RGD:9068941
plasmacytic leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD40 CD40 molecule JBrowse link 24 33,352,992 33,383,488 RGD:9068941
G TERT telomerase reverse transcriptase JBrowse link 34 11,288,622 11,307,790 RGD:9068941
polycythemia vera term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL2L1 BCL2 like 1 JBrowse link 24 21,145,214 21,209,425 RGD:9068941
G CD36 CD36 molecule JBrowse link 18 20,299,808 20,375,856 RGD:9068941
G ELANE elastase, neutrophil expressed JBrowse link 20 57,789,044 57,790,932 RGD:9068941
G EPOR erythropoietin receptor JBrowse link 20 49,945,777 49,950,856 RGD:9068941
G GSR glutathione-disulfide reductase JBrowse link 16 33,633,949 33,680,411 RGD:9068941
G HFE homeostatic iron regulator JBrowse link 35 24,031,479 24,038,922 RGD:9068941
G INSL6 insulin like 6 JBrowse link 1 93,457,854 93,474,777 RGD:9068941
G JAK1 Janus kinase 1 JBrowse link 5 45,251,653 45,408,571 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 1 93,321,055 93,438,898 RGD:7240710
RGD:9068941
G LOC100855540 hemoglobin subunit alpha-like JBrowse link 6 40,324,378 40,325,427 RGD:9068941
G LOC609402 hemoglobin subunit beta-like JBrowse link 21 28,187,535 28,188,991 RGD:9068941
Thrombocythemia 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MPL MPL proto-oncogene, thrombopoietin receptor JBrowse link 15 16,815,102 16,825,321 RGD:7240710
RGD:9068941
Thrombocythemia 3 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G INSL6 insulin like 6 JBrowse link 1 93,457,854 93,474,777 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 1 93,321,055 93,438,898 RGD:7240710
RGD:9068941
Thrombocytopenia, Anemia, and Myelofibrosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MPIG6B megakaryocyte and platelet inhibitory receptor G6b JBrowse link 12 1,202,297 1,205,867 RGD:7240710
RGD:9068941
thrombocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CALR calreticulin JBrowse link 20 49,251,390 49,255,291 RGD:9068941
G CPB2 carboxypeptidase B2 JBrowse link 22 5,074,805 5,126,635 RGD:9068941
G EPOR erythropoietin receptor JBrowse link 20 49,945,777 49,950,856 RGD:9068941
G IL1B interleukin 1 beta JBrowse link 17 37,019,329 37,033,388 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 1 93,321,055 93,438,898 RGD:9068941
G MPL MPL proto-oncogene, thrombopoietin receptor JBrowse link 15 16,815,102 16,825,321 RGD:9068941
G THPO thrombopoietin JBrowse link 34 17,245,006 17,255,250 RGD:9068941
Thrombocytosis, Benign Familial Microcytic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MPL MPL proto-oncogene, thrombopoietin receptor JBrowse link 15 16,815,102 16,825,321 RGD:9068941
transient myeloproliferative syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GATA1 GATA binding protein 1 JBrowse link X 41,991,321 41,998,319 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 11951
    disease of anatomical entity 11600
      hematopoietic system disease 1287
        bone marrow disease 383
          myeloid neoplasm 216
            Acute Erythroblastic Leukemia + 13
            Chronic Myeloproliferative Disorder with Eosinophilia 1
            Leukemoid Reaction + 2
            Myeloproliferative Disease, Autosomal Recessive 0
            chronic myeloid leukemia + 78
            chronic neutrophilic leukemia 1
            multiple myeloma + 99
            myelodysplastic/myeloproliferative neoplasm + 29
            myelofibrosis + 24
            myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1 + 0
            myelophthisic anemia 0
            myeloproliferative neoplasm + 37
            thrombocytosis + 24
Path 2
Term Annotations click to browse term
  disease 11951
    disease of anatomical entity 11600
      Hemic and Lymphatic Diseases 1549
        hematopoietic system disease 1287
          Hematologic Neoplasms 730
            hematologic cancer 730
              bone marrow cancer 276
                myeloid neoplasm 216
                  Acute Erythroblastic Leukemia + 13
                  Chronic Myeloproliferative Disorder with Eosinophilia 1
                  Leukemoid Reaction + 2
                  Myeloproliferative Disease, Autosomal Recessive 0
                  chronic myeloid leukemia + 78
                  chronic neutrophilic leukemia 1
                  multiple myeloma + 99
                  myelodysplastic/myeloproliferative neoplasm + 29
                  myelofibrosis + 24
                  myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1 + 0
                  myelophthisic anemia 0
                  myeloproliferative neoplasm + 37
                  thrombocytosis + 24
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.