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ONTOLOGY REPORT - ANNOTATIONS


Term:myeloid neoplasm
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Accession:DOID:0070004 term browser browse the term
Definition:Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE.
Synonyms:exact_synonym: Myeloproliferative Disorder;   Myeloproliferative Disorders;   myeloma
 primary_id: MESH:D009196;   RDO:0004832
For additional species annotation, visit the Alliance of Genome Resources.


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myeloid neoplasm term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ALOX12 arachidonate 12-lipoxygenase, 12S type JBrowse link 12 52,401,861 52,414,913 RGD:9068941
G ATG2B autophagy related 2B JBrowse link 7 117,506,298 117,586,651 RGD:9068941
G BCR BCR activator of RhoGEF and GTPase JBrowse link 14 49,208,662 49,322,109 RGD:9068941
G CBL Cbl proto-oncogene JBrowse link 9 46,416,937 46,512,855 RGD:9068941
G CD36 CD36 molecule JBrowse link 9 99,685,748 99,782,296 RGD:9068941
G CSF1R colony stimulating factor 1 receptor JBrowse link 2 151,102,138 151,130,311 RGD:9068941
G EGR1 early growth response 1 JBrowse link 2 140,440,829 140,445,302 RGD:9068941
G ETV6 ETS variant 6 JBrowse link 5 60,523,530 60,776,792 RGD:9068941
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 9 109,384,976 109,450,943 RGD:9068941
G F3 coagulation factor III, tissue factor JBrowse link 4 122,827,018 122,837,673 RGD:9068941
G FGFR1 fibroblast growth factor receptor 1 JBrowse link 15 48,053,895 48,106,634 RGD:9068941
G FGFR1OP2 FGFR1 oncogene partner 2 JBrowse link 5 46,794,118 46,824,062 RGD:9068941
G FGFR3 fibroblast growth factor receptor 3 JBrowse link 8 879,151 894,968 RGD:9068941
G FLT3 fms related tyrosine kinase 3 JBrowse link 11 5,370,475 5,455,439 RGD:9068941
G GFI1 growth factor independent 1 transcriptional repressor JBrowse link 4 124,619,887 124,629,638 RGD:9068941
G GFI1B growth factor independent 1B transcriptional repressor JBrowse link 1 272,701,386 272,715,551 RGD:9068941
G GPX1 glutathione peroxidase 1 JBrowse link 13 31,916,269 31,917,337 RGD:9068941
G GSKIP GSK3B interacting protein JBrowse link 7 117,586,742 117,607,575 RGD:9068941
G HSPA5 heat shock protein family A (Hsp70) member 5 JBrowse link 1 265,930,044 265,934,959 RGD:9068941
G INSL6 insulin like 6 JBrowse link 1 216,792,785 216,820,197 RGD:9068941
G IRF4 interferon regulatory factor 4 JBrowse link 7 133,358 149,609 RGD:9068941
G IRF8 interferon regulatory factor 8 JBrowse link 6 3,041,617 3,060,685 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 1 216,849,744 217,002,310 RGD:9068941
G KRAS KRAS proto-oncogene, GTPase JBrowse link 5 48,508,774 48,546,260 RGD:9068941
G MECOM MDS1 and EVI1 complex locus JBrowse link 13 107,753,207 108,336,136 RGD:9068941
G MTHFR methylenetetrahydrofolate reductase JBrowse link 6 71,863,637 71,882,118 RGD:9068941
G NPM1 nucleophosmin 1 JBrowse link 16 52,767,263 52,781,862 RGD:9068941
G NQO1 NAD(P)H quinone dehydrogenase 1 JBrowse link 6 17,292,962 17,302,593 RGD:9068941
G NQO2 N-ribosyldihydronicotinamide:quinone reductase 2 JBrowse link 7 1,792,745 1,805,916 RGD:9068941
G NRAS NRAS proto-oncogene, GTPase JBrowse link 4 105,845,913 105,853,769 RGD:9068941
G RUNX1 RUNX family transcription factor 1 JBrowse link 13 198,371,835 198,635,648 RGD:9068941
G ZMYM2 zinc finger MYM-type containing 2 JBrowse link 11 661,314 731,030 RGD:9068941
Acute Erythroblastic Leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase JBrowse link 3 111,887,017 111,914,511 RGD:9068941
G DHODH dihydroorotate dehydrogenase (quinone) JBrowse link 6 14,942,898 14,956,000 RGD:9068941
G UMPS uridine monophosphate synthetase JBrowse link 13 135,611,857 135,650,656 RGD:9068941
Acute Erythroleukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DDX41 DEAD-box helicase 41 JBrowse link 2 80,433,065 80,445,484 RGD:9068941
G ERBB3 erb-b2 receptor tyrosine kinase 3 JBrowse link 5 21,474,218 21,495,040 RGD:9068941
G FLT3 fms related tyrosine kinase 3 JBrowse link 11 5,370,475 5,455,439 RGD:9068941
G GFI1B growth factor independent 1B transcriptional repressor JBrowse link 1 272,701,386 272,715,551 RGD:9068941
G KMT2A lysine methyltransferase 2A JBrowse link 9 45,743,566 45,828,559 RGD:9068941
G NPM1 nucleophosmin 1 JBrowse link 16 52,767,263 52,781,862 RGD:9068941
G NUP98 nucleoporin 98 JBrowse link 9 6,319,616 6,419,652 RGD:9068941
G RB1 RB transcriptional corepressor 1 JBrowse link 11 19,186,754 19,317,642 RGD:9068941
G TP53 tumor protein p53 JBrowse link 12 52,939,643 52,953,786 RGD:9068941
atypical chronic myeloid leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FGFR1 fibroblast growth factor receptor 1 JBrowse link 15 48,053,895 48,106,634 RGD:9068941
G SETBP1 SET binding protein 1 JBrowse link 1 94,295,332 94,666,560 RGD:9068941
Blast Crisis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AICDA activation induced cytidine deaminase JBrowse link 5 62,777,236 62,787,342 RGD:9068941
G BCR BCR activator of RhoGEF and GTPase JBrowse link 14 49,208,662 49,322,109 RGD:9068941
G ESR2 estrogen receptor 2 JBrowse link 1 193,823,666 193,907,330 RGD:9068941
G HMOX1 heme oxygenase 1 RGD:9068941
G MIR150-1 microRNA mir-150-1 JBrowse link 6 54,580,912 54,580,988 RGD:9068941
G TCN2 transcobalamin 2 JBrowse link 14 47,496,245 47,515,966 RGD:9068941
chronic myeloid leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 JBrowse link 9 93,049,955 93,146,469 RGD:9068941
G ABCC2 ATP binding cassette subfamily C member 2 JBrowse link 14 110,955,698 111,038,898 RGD:9068941
G ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 JBrowse link 8 130,853,414 130,945,388 RGD:9068941
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 1 270,761,641 270,906,708 RGD:7240710
RGD:9068941
G ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 JBrowse link 12 15,394,487 15,414,609 RGD:9068941
G AGT angiotensinogen JBrowse link 14 59,643,030 59,656,835 RGD:9068941
G AKT1 AKT serine/threonine kinase 1 RGD:9068941
G ALOX5 arachidonate 5-lipoxygenase JBrowse link 14 90,859,209 90,907,084 RGD:9068941
G ARNTL aryl hydrocarbon receptor nuclear translocator like JBrowse link 2 45,895,637 46,025,174 RGD:9068941
G BCL2L1 BCL2 like 1 JBrowse link 17 35,366,139 35,415,798 RGD:9068941
G BCR BCR activator of RhoGEF and GTPase JBrowse link 14 49,208,662 49,322,109 RGD:7240710
RGD:9068941
G BIRC5 baculoviral IAP repeat containing 5 JBrowse link 12 3,747,276 3,755,214 RGD:9068941
G BRAF B-Raf proto-oncogene, serine/threonine kinase JBrowse link 18 8,957,963 9,132,558 RGD:9068941
G CA9 carbonic anhydrase 9 JBrowse link 1 236,393,727 236,400,994 RGD:9068941
G CD36 CD36 molecule JBrowse link 9 99,685,748 99,782,296 RGD:9068941
G CD40 CD40 molecule JBrowse link 17 48,286,116 48,298,188 RGD:9068941
G CDKN1B cyclin dependent kinase inhibitor 1B JBrowse link 5 59,731,224 59,735,831 RGD:9068941
G CHORDC1 cysteine and histidine rich domain containing 1 JBrowse link 9 23,187,770 23,208,592 RGD:9068941
G CRKL CRK like proto-oncogene, adaptor protein JBrowse link 14 50,528,950 50,558,664 RGD:9068941
G CRY1 cryptochrome circadian regulator 1 JBrowse link 5 13,275,265 13,429,566 RGD:9068941
G CRY2 cryptochrome circadian regulator 2 JBrowse link 2 16,587,101 16,620,380 RGD:9068941
G CSF3R colony stimulating factor 3 receptor JBrowse link 6 92,550,159 92,565,798 RGD:9068941
G CYP1A1 cytochrome P450 1A1 JBrowse link 7 58,802,887 58,809,155 RGD:9068941
G DNMT1 DNA methyltransferase 1 JBrowse link 2 68,981,564 69,040,364 RGD:9068941
G DNMT3A DNA methyltransferase 3 alpha JBrowse link 3 113,501,972 113,609,148 RGD:9068941
G DNMT3B DNA methyltransferase 3 beta JBrowse link 17 36,345,715 36,386,076 RGD:9068941
G E2F1 E2F transcription factor 1 JBrowse link 17 37,178,587 37,190,118 RGD:9068941
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 6 51,734,318 51,757,508 RGD:9068941
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 9 109,384,976 109,450,943 RGD:9068941
G FAS Fas cell surface death receptor JBrowse link 14 100,927,305 100,954,781 RGD:9068941
G FASLG Fas ligand (TNF superfamily, member 6) JBrowse link 9 115,068,314 115,075,147 RGD:9068941
G GAB2 GRB2 associated binding protein 2 JBrowse link 9 12,663,658 12,851,423 RGD:9068941
G GPX1 glutathione peroxidase 1 JBrowse link 13 31,916,269 31,917,337 RGD:9068941
G HES1 hes family bHLH transcription factor 1 JBrowse link 13 131,135,970 131,137,865 RGD:9068941
G HMMR hyaluronan mediated motility receptor JBrowse link 16 60,290,684 60,332,411 RGD:9068941
G HMOX1 heme oxygenase 1 RGD:9068941
G HSPA5 heat shock protein family A (Hsp70) member 5 JBrowse link 1 265,930,044 265,934,959 RGD:9068941
G IL10 interleukin 10 JBrowse link 9 67,400,727 67,405,941 RGD:9068941
G IL1RN interleukin 1 receptor antagonist RGD:9068941
G INSL6 insulin like 6 JBrowse link 1 216,792,785 216,820,197 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 1 216,849,744 217,002,310 RGD:9068941
G KIT KIT proto-oncogene, receptor tyrosine kinase JBrowse link 8 41,402,334 41,492,306 RGD:9068941
G LOC100739163 glutathione S-transferase P-like JBrowse link 2 4,978,761 4,982,233 RGD:9068941
G LOC110258578 interleukin-1 beta-like RGD:9068941
G MAPK14 mitogen-activated protein kinase 14 JBrowse link 7 31,791,398 31,861,544 RGD:9068941
G MDM2 MDM2 proto-oncogene JBrowse link 5 33,105,717 33,137,602 RGD:9068941
G MIR150-1 microRNA mir-150-1 JBrowse link 6 54,580,912 54,580,988 RGD:9068941
G MLF1 myeloid leukemia factor 1 JBrowse link 13 98,357,804 98,405,801 RGD:9068941
G MTHFR methylenetetrahydrofolate reductase JBrowse link 6 71,863,637 71,882,118 RGD:9068941
G NCSTN nicastrin JBrowse link 4 90,121,209 90,142,934 RGD:9068941
G NPM1 nucleophosmin 1 JBrowse link 16 52,767,263 52,781,862 RGD:9068941
G NQO1 NAD(P)H quinone dehydrogenase 1 JBrowse link 6 17,292,962 17,302,593 RGD:9068941
G NRAS NRAS proto-oncogene, GTPase JBrowse link 4 105,845,913 105,853,769 RGD:9068941
G P14ARF p14ARF protein JBrowse link 1 200,774,496 200,799,149 RGD:9068941
G PECAM1 platelet and endothelial cell adhesion molecule 1 JBrowse link 12 14,667,643 14,723,296 RGD:9068941
G PER1 period circadian regulator 1 JBrowse link 12 53,361,863 53,376,723 RGD:9068941
G PER2 period circadian regulator 2 JBrowse link 15 137,793,419 137,837,854 RGD:9068941
G PER3 period circadian regulator 3 JBrowse link 6 68,487,634 68,548,718 RGD:9068941
G PRAME preferentially expressed antigen in melanoma JBrowse link 14 48,901,097 48,906,855 RGD:9068941
G PRTN3 proteinase 3 JBrowse link 2 77,520,314 77,526,303 RGD:9068941
G SETBP1 SET binding protein 1 JBrowse link 1 94,295,332 94,666,560 RGD:9068941
G SH2B3 SH2B adaptor protein 3 JBrowse link 14 32,623,286 32,664,606 RGD:9068941
G SIPA1 signal-induced proliferation-associated 1 JBrowse link 2 6,606,613 6,618,556 RGD:9068941
G SMAD4 SMAD family member 4 JBrowse link 1 100,521,843 100,633,501 RGD:9068941
G SRSF1 serine and arginine rich splicing factor 1 JBrowse link 12 34,278,363 34,282,164 RGD:9068941
G TERT telomerase reverse transcriptase JBrowse link 16 79,258,591 79,276,421 RGD:9068941
G TGFB1 transforming growth factor beta 1 JBrowse link 6 49,332,169 49,348,642 RGD:9068941
G VEGFA vascular endothelial growth factor A JBrowse link 7 38,746,393 38,762,282 RGD:9068941
G WT1 WT1 transcription factor JBrowse link 2 28,411,467 28,456,007 RGD:9068941
G XRCC1 X-ray repair cross complementing 1 JBrowse link 6 50,403,691 50,425,730 RGD:9068941
chronic myelomonocytic leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ASXL1 ASXL transcriptional regulator 1 JBrowse link 17 35,985,978 36,067,122 RGD:9068941
G CDKN2B cyclin dependent kinase inhibitor 2B JBrowse link 1 200,666,250 200,770,880 RGD:9068941
G CSF3R colony stimulating factor 3 receptor JBrowse link 6 92,550,159 92,565,798 RGD:9068941
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 9 109,384,976 109,450,943 RGD:9068941
G KDM6A lysine demethylase 6A JBrowse link X 39,953,764 40,154,197 RGD:9068941
G NRAS NRAS proto-oncogene, GTPase JBrowse link 4 105,845,913 105,853,769 RGD:9068941
G TET2 tet methylcytosine dioxygenase 2 JBrowse link 8 116,413,253 116,546,976 RGD:9068941
Chronic Myeloproliferative Disorder with Eosinophilia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PDGFRB platelet derived growth factor receptor beta JBrowse link 2 151,155,753 151,192,818 RGD:7240710
RGD:9068941
chronic neutrophilic leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CSF3R colony stimulating factor 3 receptor JBrowse link 6 92,550,159 92,565,798 RGD:9068941
essential thrombocythemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATG2B autophagy related 2B JBrowse link 7 117,506,298 117,586,651 RGD:9068941
G BDKRB1 bradykinin receptor B1 JBrowse link 7 117,491,350 117,492,410 RGD:9068941
G BDKRB2 bradykinin receptor B2 JBrowse link 7 117,438,622 117,472,005 RGD:9068941
G C7H14orf132 chromosome 7 C14orf132 homolog JBrowse link 7 117,242,442 117,291,577 RGD:9068941
G CALR calreticulin JBrowse link 2 66,098,263 66,102,074 RGD:7240710
RGD:9068941
G CD36 CD36 molecule JBrowse link 9 99,685,748 99,782,296 RGD:9068941
G CD40LG CD40 ligand JBrowse link X 111,778,666 111,788,901 RGD:9068941
G ELANE elastase, neutrophil expressed JBrowse link 2 77,513,769 77,516,118 RGD:9068941
G FGF2 fibroblast growth factor 2 JBrowse link 8 101,278,877 101,344,084 RGD:9068941
G GSKIP GSK3B interacting protein JBrowse link 7 117,586,742 117,607,575 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 1 216,849,744 217,002,310 RGD:9068941
G MPL MPL proto-oncogene, thrombopoietin receptor JBrowse link 6 167,896,191 167,908,988 RGD:9068941
G MYB MYB proto-oncogene, transcription factor JBrowse link 1 28,819,500 28,856,222 RGD:9068941
G PDGFA platelet derived growth factor subunit A JBrowse link 3 296,399 322,967 RGD:9068941
G PDGFB platelet derived growth factor subunit B RGD:9068941
G SH2B3 SH2B adaptor protein 3 JBrowse link 14 32,623,286 32,664,606 RGD:7240710
RGD:9068941
G TCL1A T cell leukemia/lymphoma 1A JBrowse link 7 116,933,785 116,939,353 RGD:9068941
G TGFB1 transforming growth factor beta 1 JBrowse link 6 49,332,169 49,348,642 RGD:9068941
G THPO thrombopoietin JBrowse link 13 122,259,654 122,267,860 RGD:7240710
RGD:9068941
G VCAM1 vascular cell adhesion molecule 1 JBrowse link 4 117,496,914 117,511,211 RGD:9068941
G VWF von Willebrand factor JBrowse link 5 64,516,627 64,655,938 RGD:9068941
familial chronic myelocytic leukemia-like syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IRF8 interferon regulatory factor 8 JBrowse link 6 3,041,617 3,060,685 RGD:9068941
Familial Myelofibrosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GATA1 GATA binding protein 1 JBrowse link X 42,898,431 42,905,939 RGD:9068941
G MPL MPL proto-oncogene, thrombopoietin receptor JBrowse link 6 167,896,191 167,908,988 RGD:9068941
G VPS45 vacuolar protein sorting 45 homolog JBrowse link 4 98,939,585 99,010,554 RGD:9068941
juvenile myelomonocytic leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKAP12 A-kinase anchoring protein 12 JBrowse link 1 14,904,109 15,017,016 RGD:9068941
G ARHGAP26 Rho GTPase activating protein 26 JBrowse link 2 144,301,234 144,778,090 RGD:7240710
RGD:9068941
G ASXL1 ASXL transcriptional regulator 1 JBrowse link 17 35,985,978 36,067,122 RGD:9068941
G CBL Cbl proto-oncogene JBrowse link 9 46,416,937 46,512,855 RGD:7240710
RGD:9068941
G CSF2 colony stimulating factor 2 JBrowse link 2 134,354,724 134,357,155 RGD:9068941
G DNMT3A DNA methyltransferase 3 alpha JBrowse link 3 113,501,972 113,609,148 RGD:9068941
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 9 109,384,976 109,450,943 RGD:9068941
G FLT3 fms related tyrosine kinase 3 JBrowse link 11 5,370,475 5,455,439 RGD:9068941
G GATA2 GATA binding protein 2 JBrowse link 13 71,981,139 71,997,626 RGD:9068941
G JAK3 Janus kinase 3 JBrowse link 2 59,905,901 59,926,504 RGD:9068941
G KRAS KRAS proto-oncogene, GTPase JBrowse link 5 48,508,774 48,546,260 RGD:9068941
G NF1 neurofibromin 1 JBrowse link 12 43,487,098 43,754,205 RGD:7240710
RGD:9068941
G NRAS NRAS proto-oncogene, GTPase JBrowse link 4 105,845,913 105,853,769 RGD:9068941
G PTPN11 protein tyrosine phosphatase non-receptor type 11 JBrowse link 14 39,202,165 39,292,041 RGD:7240710
RGD:9068941
G RAC2 Rac family small GTPase 2 JBrowse link 5 10,553,986 10,571,082 RGD:9068941
G RRAS RAS related JBrowse link 6 54,680,596 54,684,714 RGD:9068941
G RRAS2 RAS related 2 JBrowse link 2 44,890,129 44,961,003 RGD:9068941
G RUNX1 RUNX family transcription factor 1 JBrowse link 13 198,371,835 198,635,648 RGD:9068941
G SETBP1 SET binding protein 1 JBrowse link 1 94,295,332 94,666,560 RGD:9068941
G SH2B3 SH2B adaptor protein 3 JBrowse link 14 32,623,286 32,664,606 RGD:9068941
G ZRSR2 zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2 JBrowse link X 12,336,635 12,365,071 RGD:9068941
Leukemoid Reaction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G JAK3 Janus kinase 3 JBrowse link 2 59,905,901 59,926,504 RGD:9068941
multiple myeloma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 JBrowse link 8 130,853,414 130,945,388 RGD:9068941
G ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 JBrowse link 12 15,394,487 15,414,609 RGD:9068941
G ALB albumin JBrowse link 8 69,643,427 69,663,152 RGD:9068941
G APOE apolipoprotein E JBrowse link 6 51,373,113 51,375,333 RGD:9068941
G B2M beta-2-microglobulin JBrowse link 1 126,837,721 126,844,043 RGD:9068941
G BCL2 BCL2 apoptosis regulator JBrowse link 1 158,337,403 158,518,214 RGD:9068941
G BCL2L1 BCL2 like 1 JBrowse link 17 35,366,139 35,415,798 RGD:9068941
G BCL2L10 BCL2 like 10 JBrowse link 1 119,594,004 119,607,709 RGD:9068941
G BNIP3 BCL2 interacting protein 3 JBrowse link 14 140,362,123 140,371,951 RGD:9068941
G BRAF B-Raf proto-oncogene, serine/threonine kinase JBrowse link 18 8,957,963 9,132,558 RGD:9068941
G BTG1 BTG anti-proliferation factor 1 JBrowse link 5 90,815,194 90,817,936 RGD:9068941
G CBL Cbl proto-oncogene JBrowse link 9 46,416,937 46,512,855 RGD:9068941
G CBX7 chromobox 7 JBrowse link 5 9,070,312 9,090,467 RGD:9068941
G CCL2 chemokine (C-C motif) ligand 2 JBrowse link 12 40,798,109 40,800,013 RGD:9068941
G CCND1 cyclin D1 JBrowse link 2 3,621,242 3,633,380 RGD:7240710
RGD:9068941
G CCND2 cyclin D2 JBrowse link 5 66,092,483 66,114,575 RGD:9068941
G CCND3 cyclin D3 JBrowse link 7 37,087,336 37,182,462 RGD:9068941
G CD40 CD40 molecule JBrowse link 17 48,286,116 48,298,188 RGD:9068941
G CD40LG CD40 ligand JBrowse link X 111,778,666 111,788,901 RGD:9068941
G CD46 CD46 molecule, complement regulatory protein JBrowse link 9 135,025,439 135,078,910 RGD:9068941
G CD86 CD86 molecule JBrowse link 13 138,427,573 138,504,307 RGD:9068941
G CDK4 cyclin dependent kinase 4 JBrowse link 5 23,039,206 23,041,959 RGD:9068941
G CHI3L1 chitinase 3 like 1 JBrowse link 9 113,885,541 113,895,033 RGD:9068941
G CRBN cereblon JBrowse link 13 59,733,503 59,757,776 RGD:9068941
G CSF2 colony stimulating factor 2 JBrowse link 2 134,354,724 134,357,155 RGD:9068941
G CSF3 colony stimulating factor 3 JBrowse link 12 22,333,445 22,335,949 RGD:9068941
G CTLA4 cytotoxic T-lymphocyte associated protein 4 JBrowse link 15 107,283,081 107,288,041 RGD:9068941
G CYP1A1 cytochrome P450 1A1 JBrowse link 7 58,802,887 58,809,155 RGD:9068941
G CYP2C49 cytochrome P450 2C49 JBrowse link 14 106,571,803 106,612,082 RGD:9068941
G CYP2D25 vitamin D3 25-Hydroxylase JBrowse link 5 6,539,021 6,543,643 RGD:9068941
G ENG endoglin JBrowse link 1 268,309,379 268,343,861 RGD:9068941
G EPHX1 epoxide hydrolase 1 JBrowse link 10 13,757,489 13,773,071 RGD:9068941
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 6 51,783,537 51,808,898 RGD:9068941
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 6 51,734,318 51,757,508 RGD:9068941
G FASLG Fas ligand (TNF superfamily, member 6) JBrowse link 9 115,068,314 115,075,147 RGD:9068941
G FGFR3 fibroblast growth factor receptor 3 JBrowse link 8 879,151 894,968 RGD:9068941
G FGG fibrinogen gamma chain JBrowse link 8 74,553,040 74,562,151 RGD:9068941
G GPX1 glutathione peroxidase 1 JBrowse link 13 31,916,269 31,917,337 RGD:9068941
G HFE homeostatic iron regulator JBrowse link 7 20,758,604 20,767,004 RGD:9068941
G HK1 hexokinase 1 JBrowse link 14 72,383,328 72,460,927 RGD:9068941
G HRAS HRas proto-oncogene, GTPase JBrowse link 2 299,662 302,539 RGD:9068941
G HSPB1 heat shock protein family B (small) member 1 JBrowse link 3 10,038,074 10,039,441 RGD:9068941
G ICAM1 intercellular adhesion molecule 1 JBrowse link 2 69,097,136 69,107,722 RGD:9068941
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 JBrowse link 15 111,341,153 111,362,330 RGD:9068941
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 JBrowse link 7 55,654,298 55,675,571 RGD:9068941
G IL10 interleukin 10 JBrowse link 9 67,400,727 67,405,941 RGD:9068941
G IL1A interleukin 1 alpha JBrowse link 3 43,718,320 43,731,668 RGD:9068941
G IL1RN interleukin 1 receptor antagonist RGD:9068941
G IL4R interleukin 4 receptor JBrowse link 3 19,526,343 19,576,792 RGD:9068941
G IL6 interleukin 6 JBrowse link 9 91,506,421 91,510,830 RGD:9068941
G IRF4 interferon regulatory factor 4 JBrowse link 7 133,358 149,609 RGD:9068941
G KRAS KRAS proto-oncogene, GTPase JBrowse link 5 48,508,774 48,546,260 RGD:9068941
G LIG4 DNA ligase 4 JBrowse link 11 75,537,027 75,547,711 RGD:7240710
RGD:9068941
G LOC100511376 E3 SUMO-protein ligase RanBP2 JBrowse link 3 47,531,362 47,601,328 RGD:9068941
G LOC100739163 glutathione S-transferase P-like JBrowse link 2 4,978,761 4,982,233 RGD:9068941
G LOC110258578 interleukin-1 beta-like RGD:9068941
G LRRC56 leucine rich repeat containing 56 JBrowse link 2 303,836 323,701 RGD:9068941
G MAF MAF bZIP transcription factor JBrowse link 6 8,468,736 8,910,012 RGD:9068941
G MCL1 MCL1 apoptosis regulator, BCL2 family member JBrowse link 4 98,562,092 98,567,014 RGD:9068941
G MEFV MEFV innate immuity regulator, pyrin JBrowse link 3 38,934,573 38,948,609 RGD:9068941
G MET MET proto-oncogene, receptor tyrosine kinase JBrowse link 18 29,426,044 29,541,526 RGD:9068941
G MIR19A microRNA mir-19a JBrowse link 11 60,734,939 60,735,020 RGD:9068941
G MIR92A-1 microRNA mir-92a-1 JBrowse link 11 60,735,358 60,735,437 RGD:9068941
G MTHFR methylenetetrahydrofolate reductase JBrowse link 6 71,863,637 71,882,118 RGD:9068941
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase JBrowse link 14 54,546,978 54,652,780 RGD:9068941
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase JBrowse link 16 74,245,214 74,270,828 RGD:9068941
G MUC1 mucin 1, cell surface associated JBrowse link 4 94,626,317 94,631,194 RGD:9068941
G MYD88 MYD88 innate immune signal transduction adaptor JBrowse link 13 22,976,951 22,979,568 RGD:9068941
G NFKBIA NFKB inhibitor alpha JBrowse link 7 64,508,119 64,510,754 RGD:9068941
G NOTCH2 notch receptor 2 JBrowse link 4 100,951,522 101,152,348 RGD:9068941
G NQO1 NAD(P)H quinone dehydrogenase 1 JBrowse link 6 17,292,962 17,302,593 RGD:9068941
G NRAS NRAS proto-oncogene, GTPase JBrowse link 4 105,845,913 105,853,769 RGD:9068941
G NUAK1 NUAK family kinase 1 JBrowse link 5 14,089,584 14,177,584 RGD:9068941
G P14ARF p14ARF protein JBrowse link 1 200,774,496 200,799,149 RGD:9068941
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 10 14,203,157 14,241,164 RGD:9068941
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 13 117,193,935 117,282,151 RGD:9068941
G PON1 paraoxonase 1 JBrowse link 9 74,943,646 74,974,720 RGD:9068941
G PRAME preferentially expressed antigen in melanoma JBrowse link 14 48,901,097 48,906,855 RGD:9068941
G PSORS1C2 psoriasis susceptibility 1 candidate 2 JBrowse link 7 23,540,341 23,543,136 RGD:9068941
G PTHLH parathyroid hormone like hormone JBrowse link 5 45,750,968 45,763,421 RGD:9068941
G PTPN11 protein tyrosine phosphatase non-receptor type 11 JBrowse link 14 39,202,165 39,292,041 RGD:9068941
G RUNX1 RUNX family transcription factor 1 JBrowse link 13 198,371,835 198,635,648 RGD:9068941
G SOD2 superoxide dismutase 2 JBrowse link 1 7,679,352 7,689,564 RGD:9068941
G SPARC secreted protein acidic and cysteine rich JBrowse link 16 71,368,164 71,380,972 RGD:9068941
G SPP1 secreted phosphoprotein 1 JBrowse link 8 131,077,786 131,085,334 RGD:9068941
G TERT telomerase reverse transcriptase JBrowse link 16 79,258,591 79,276,421 RGD:9068941
G TFRC transferrin receptor JBrowse link 13 133,976,765 133,997,554 RGD:9068941
G TGFB1 transforming growth factor beta 1 JBrowse link 6 49,332,169 49,348,642 RGD:9068941
G TNF tumor necrosis factor JBrowse link 7 23,699,635 23,702,393 RGD:9068941
G TNFRSF13B TNF receptor superfamily member 13B JBrowse link 12 61,245,976 61,270,154 RGD:9068941
G TNFRSF17 TNF receptor superfamily member 17 JBrowse link 3 31,137,672 31,141,862 RGD:9068941
G TP53 tumor protein p53 JBrowse link 12 52,939,643 52,953,786 RGD:9068941
G TYMS thymidylate synthetase JBrowse link 6 105,642,730 105,660,279 RGD:9068941
G ULK4 unc-51 like kinase 4 JBrowse link 13 25,207,890 25,751,465 RGD:9068941
G VEGFA vascular endothelial growth factor A JBrowse link 7 38,746,393 38,762,282 RGD:9068941
G XPO5 exportin 5 JBrowse link 7 38,530,704 38,569,558 RGD:9068941
G XRCC4 X-ray repair cross complementing 4 JBrowse link 2 91,358,348 91,643,697 RGD:9068941
G XRCC5 X-ray repair cross complementing 5 JBrowse link 15 118,354,943 118,451,974 RGD:9068941
myelodysplastic/myeloproliferative neoplasm term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DDX41 DEAD-box helicase 41 JBrowse link 2 80,433,065 80,445,484 RGD:9068941
G DIDO1 death inducer-obliterator 1 JBrowse link 17 62,126,026 62,174,095 RGD:9068941
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 9 109,384,976 109,450,943 RGD:9068941
myelofibrosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ASXL1 ASXL transcriptional regulator 1 JBrowse link 17 35,985,978 36,067,122 RGD:9068941
G ATG2B autophagy related 2B JBrowse link 7 117,506,298 117,586,651 RGD:9068941
G BDKRB1 bradykinin receptor B1 JBrowse link 7 117,491,350 117,492,410 RGD:9068941
G BDKRB2 bradykinin receptor B2 JBrowse link 7 117,438,622 117,472,005 RGD:9068941
G C7H14orf132 chromosome 7 C14orf132 homolog JBrowse link 7 117,242,442 117,291,577 RGD:9068941
G CALR calreticulin JBrowse link 2 66,098,263 66,102,074 RGD:7240710
RGD:9068941
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 6 51,783,537 51,808,898 RGD:9068941
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link 6 51,734,318 51,757,508 RGD:9068941
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 9 109,384,976 109,450,943 RGD:9068941
G FLT3 fms related tyrosine kinase 3 JBrowse link 11 5,370,475 5,455,439 RGD:9068941
G GATA1 GATA binding protein 1 JBrowse link X 42,898,431 42,905,939 RGD:9068941
G GSKIP GSK3B interacting protein JBrowse link 7 117,586,742 117,607,575 RGD:9068941
G HFE homeostatic iron regulator JBrowse link 7 20,758,604 20,767,004 RGD:9068941
G INSL6 insulin like 6 JBrowse link 1 216,792,785 216,820,197 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 1 216,849,744 217,002,310 RGD:7240710
RGD:9068941
G MPL MPL proto-oncogene, thrombopoietin receptor JBrowse link 6 167,896,191 167,908,988 RGD:7240710
RGD:9068941
G MYB MYB proto-oncogene, transcription factor JBrowse link 1 28,819,500 28,856,222 RGD:9068941
G NCOR2 nuclear receptor corepressor 2 JBrowse link 14 28,642,774 28,819,404 RGD:9068941
G SH2B3 SH2B adaptor protein 3 JBrowse link 14 32,623,286 32,664,606 RGD:7240710
RGD:9068941
G TCL1A T cell leukemia/lymphoma 1A JBrowse link 7 116,933,785 116,939,353 RGD:9068941
G TGFB1 transforming growth factor beta 1 JBrowse link 6 49,332,169 49,348,642 RGD:9068941
G TP53 tumor protein p53 JBrowse link 12 52,939,643 52,953,786 RGD:9068941
Myeloid Leukemia, Accelerated Phase term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BMI1 BMI1 proto-oncogene, polycomb ring finger JBrowse link 10 52,586,089 52,596,154 RGD:9068941
G MIR150-1 microRNA mir-150-1 JBrowse link 6 54,580,912 54,580,988 RGD:9068941
Myeloid Leukemia, Chronic-Phase term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 1 270,761,641 270,906,708 RGD:9068941
G BCR BCR activator of RhoGEF and GTPase JBrowse link 14 49,208,662 49,322,109 RGD:9068941
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 6 51,783,537 51,808,898 RGD:9068941
G GFI1 growth factor independent 1 transcriptional repressor JBrowse link 4 124,619,887 124,629,638 RGD:9068941
G GFI1B growth factor independent 1B transcriptional repressor JBrowse link 1 272,701,386 272,715,551 RGD:9068941
myeloproliferative neoplasm term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CSF3R colony stimulating factor 3 receptor JBrowse link 6 92,550,159 92,565,798 RGD:9068941
G DDX41 DEAD-box helicase 41 JBrowse link 2 80,433,065 80,445,484 RGD:9068941
G ETV6 ETS variant 6 JBrowse link 5 60,523,530 60,776,792 RGD:9068941
G FGFR3 fibroblast growth factor receptor 3 JBrowse link 8 879,151 894,968 RGD:9068941
G INSL6 insulin like 6 JBrowse link 1 216,792,785 216,820,197 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 1 216,849,744 217,002,310 RGD:9068941
G JAK3 Janus kinase 3 JBrowse link 2 59,905,901 59,926,504 RGD:9068941
G KIT KIT proto-oncogene, receptor tyrosine kinase JBrowse link 8 41,402,334 41,492,306 RGD:9068941
G MPL MPL proto-oncogene, thrombopoietin receptor JBrowse link 6 167,896,191 167,908,988 RGD:9068941
G PDGFRB platelet derived growth factor receptor beta JBrowse link 2 151,155,753 151,192,818 RGD:9068941
G TET2 tet methylcytosine dioxygenase 2 JBrowse link 8 116,413,253 116,546,976 RGD:9068941
Noonan Syndrome-Like Disorder with or without Juvenile Myelomonocytic Leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CBL Cbl proto-oncogene JBrowse link 9 46,416,937 46,512,855 RGD:7240710
RGD:9068941
G PTPN11 protein tyrosine phosphatase non-receptor type 11 JBrowse link 14 39,202,165 39,292,041 RGD:9068941
plasmacytic leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD40 CD40 molecule JBrowse link 17 48,286,116 48,298,188 RGD:9068941
G TERT telomerase reverse transcriptase JBrowse link 16 79,258,591 79,276,421 RGD:9068941
polycythemia vera term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL2L1 BCL2 like 1 JBrowse link 17 35,366,139 35,415,798 RGD:9068941
G CD36 CD36 molecule JBrowse link 9 99,685,748 99,782,296 RGD:9068941
G ELANE elastase, neutrophil expressed JBrowse link 2 77,513,769 77,516,118 RGD:9068941
G EPOR erythropoietin receptor JBrowse link 2 70,063,601 70,068,821 RGD:9068941
G GSR glutathione-disulfide reductase JBrowse link 15 54,382,564 54,433,989 RGD:9068941
G HFE homeostatic iron regulator JBrowse link 7 20,758,604 20,767,004 RGD:9068941
G INSL6 insulin like 6 JBrowse link 1 216,792,785 216,820,197 RGD:9068941
G JAK1 Janus kinase 1 JBrowse link 6 147,320,288 147,567,188 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 1 216,849,744 217,002,310 RGD:7240710
RGD:9068941
G LOC110259958 hemoglobin subunit alpha JBrowse link 3 41,482,353 41,483,564 RGD:9068941
Thrombocythemia 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MPL MPL proto-oncogene, thrombopoietin receptor JBrowse link 6 167,896,191 167,908,988 RGD:7240710
RGD:9068941
Thrombocythemia 3 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G INSL6 insulin like 6 JBrowse link 1 216,792,785 216,820,197 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 1 216,849,744 217,002,310 RGD:7240710
RGD:9068941
Thrombocytopenia, Anemia, and Myelofibrosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MPIG6B megakaryocyte and platelet inhibitory receptor G6b JBrowse link 7 23,834,650 23,836,784 RGD:7240710
RGD:9068941
thrombocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CALR calreticulin JBrowse link 2 66,098,263 66,102,074 RGD:9068941
G CPB2 carboxypeptidase B2 JBrowse link 11 21,234,447 21,298,250 RGD:9068941
G EPOR erythropoietin receptor JBrowse link 2 70,063,601 70,068,821 RGD:9068941
G JAK2 Janus kinase 2 JBrowse link 1 216,849,744 217,002,310 RGD:9068941
G LOC110258578 interleukin-1 beta-like RGD:9068941
G MPL MPL proto-oncogene, thrombopoietin receptor JBrowse link 6 167,896,191 167,908,988 RGD:9068941
G THPO thrombopoietin JBrowse link 13 122,259,654 122,267,860 RGD:9068941
Thrombocytosis, Benign Familial Microcytic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MPL MPL proto-oncogene, thrombopoietin receptor JBrowse link 6 167,896,191 167,908,988 RGD:9068941
transient myeloproliferative syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GATA1 GATA binding protein 1 JBrowse link X 42,898,431 42,905,939 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 11921
    disease of anatomical entity 11575
      hematopoietic system disease 1287
        bone marrow disease 378
          myeloid neoplasm 213
            Acute Erythroblastic Leukemia + 12
            Chronic Myeloproliferative Disorder with Eosinophilia 1
            Leukemoid Reaction + 2
            Myeloproliferative Disease, Autosomal Recessive 0
            chronic myeloid leukemia + 78
            chronic neutrophilic leukemia 1
            multiple myeloma + 98
            myelodysplastic/myeloproliferative neoplasm + 29
            myelofibrosis + 24
            myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1 + 0
            myelophthisic anemia 0
            myeloproliferative neoplasm + 37
            thrombocytosis + 25
Path 2
Term Annotations click to browse term
  disease 11921
    disease of anatomical entity 11575
      Hemic and Lymphatic Diseases 1541
        hematopoietic system disease 1287
          Hematologic Neoplasms 728
            hematologic cancer 728
              bone marrow cancer 273
                myeloid neoplasm 213
                  Acute Erythroblastic Leukemia + 12
                  Chronic Myeloproliferative Disorder with Eosinophilia 1
                  Leukemoid Reaction + 2
                  Myeloproliferative Disease, Autosomal Recessive 0
                  chronic myeloid leukemia + 78
                  chronic neutrophilic leukemia 1
                  multiple myeloma + 98
                  myelodysplastic/myeloproliferative neoplasm + 29
                  myelofibrosis + 24
                  myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1 + 0
                  myelophthisic anemia 0
                  myeloproliferative neoplasm + 37
                  thrombocytosis + 25
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.