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ONTOLOGY REPORT - ANNOTATIONS


Term:myeloid neoplasm
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Accession:DOID:0070004 term browser browse the term
Definition:Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE.
Synonyms:exact_synonym: Myeloproliferative Disorder;   Myeloproliferative Disorders;   myeloma
 primary_id: MESH:D009196;   RDO:0004832
For additional species annotation, visit the Alliance of Genome Resources.


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myeloid neoplasm term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atg2b autophagy related 2B JBrowse link NW_004936604 583,391 641,217 RGD:9068941
G Bcr BCR activator of RhoGEF and GTPase JBrowse link NW_004936619 288,377 432,297 RGD:9068941
G Cbl Cbl proto-oncogene JBrowse link NW_004936542 4,136,389 4,235,746 RGD:9068941
G Cd36 CD36 molecule JBrowse link NW_004936810 791,823 838,303 RGD:9068941
G Csf1r colony stimulating factor 1 receptor JBrowse link NW_004936504 4,898,947 4,927,195 RGD:9068941
G Egr1 early growth response 1 JBrowse link NW_004936531 7,625,956 7,629,041 RGD:9068941
G Etv6 ETS variant 6 JBrowse link NW_004936587 5,328,467 5,457,260 RGD:9068941
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link NW_004936527 5,024,077 5,069,152 RGD:9068941
G F3 coagulation factor III, tissue factor JBrowse link NW_004936537 4,637,028 4,647,915 RGD:9068941
G Fgfr1 fibroblast growth factor receptor 1 JBrowse link NW_004936710 1,760,365 1,815,269 RGD:9068941
G Fgfr1op2 FGFR1 oncogene partner 2 JBrowse link NW_004936548 521,418 548,290 RGD:9068941
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link NW_004936477 21,591,772 21,606,289 RGD:9068941
G Flt3 fms related tyrosine kinase 3 JBrowse link NW_004936472 23,169,967 23,239,178 RGD:9068941
G Gfi1 growth factor independent 1 transcriptional repressor JBrowse link NW_004936537 6,610,565 6,618,509 RGD:9068941
G Gfi1b growth factor independent 1B transcriptional repressor JBrowse link NW_004936487 19,414,135 19,417,465 RGD:9068941
G Gpx1 glutathione peroxidase 1 JBrowse link NW_004936529 997,943 999,123 RGD:9068941
G Gskip GSK3B interacting protein JBrowse link NW_004936604 657,602 675,702 RGD:9068941
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link NW_004936487 13,348,465 13,352,717 RGD:9068941
G Insl6 insulin like 6 JBrowse link NW_004936503 67,933 78,496 RGD:9068941
G Irf4 interferon regulatory factor 4 JBrowse link NW_004936633 1,565,293 1,580,859 RGD:9068941
G Irf8 interferon regulatory factor 8 JBrowse link NW_004936641 2,608,109 2,622,446 RGD:9068941
G Jak2 Janus kinase 2 JBrowse link NW_004936503 111,722 243,627 RGD:9068941
G Kras KRAS proto-oncogene, GTPase JBrowse link NW_004936548 2,078,568 2,113,877 RGD:9068941
G Mecom MDS1 and EVI1 complex locus JBrowse link NW_004936593 2,742,236 3,282,596 RGD:9068941
G Mthfr methylenetetrahydrofolate reductase JBrowse link NW_004936474 623,438 637,849 RGD:9068941
G Npm1 nucleophosmin 1 JBrowse link NW_004936609 3,712,628 3,725,635 RGD:9068941
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link NW_004936475 19,771,384 19,785,034 RGD:9068941
G Nras NRAS proto-oncogene, GTPase JBrowse link NW_004936627 73,413 82,590 RGD:9068941
G Runx1 RUNX family transcription factor 1 JBrowse link NW_004936500 7,621,328 7,710,909 RGD:9068941
G Zmym2 zinc finger MYM-type containing 2 JBrowse link NW_004936720 1,643,711 1,726,124 RGD:9068941
Acute Erythroblastic Leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase JBrowse link NW_004936493 5,308,268 5,332,934 RGD:9068941
G Dhodh dihydroorotate dehydrogenase (quinone) JBrowse link NW_004936475 21,863,627 21,877,660 RGD:9068941
G Umps uridine monophosphate synthetase JBrowse link NW_004936725 553,278 564,846 RGD:9068941
Acute Erythroleukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddx41 DEAD-box helicase 41 JBrowse link NW_004936597 1,787,830 1,793,352 RGD:9068941
G Erbb3 erb-b2 receptor tyrosine kinase 3 JBrowse link NW_004936646 497,783 515,247 RGD:9068941
G Flt3 fms related tyrosine kinase 3 JBrowse link NW_004936472 23,169,967 23,239,178 RGD:9068941
G Gfi1b growth factor independent 1B transcriptional repressor JBrowse link NW_004936487 19,414,135 19,417,465 RGD:9068941
G Hoxb9 homeobox B9 JBrowse link NW_004936490 12,761,668 12,765,658 RGD:9068941
G Kmt2a lysine methyltransferase 2A JBrowse link NW_004936542 3,480,071 3,566,823 RGD:9068941
G Npm1 nucleophosmin 1 JBrowse link NW_004936609 3,712,628 3,725,635 RGD:9068941
G Nup98 nucleoporin 98 JBrowse link NW_004936498 1,112,724 1,219,790 RGD:9068941
G Rb1 RB transcriptional corepressor 1 JBrowse link NW_004936565 1,596,227 1,746,706 RGD:9068941
G Tp53 tumor protein p53 JBrowse link NW_004936595 919,807 935,367 RGD:9068941
atypical chronic myeloid leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgfr1 fibroblast growth factor receptor 1 JBrowse link NW_004936710 1,760,365 1,815,269 RGD:9068941
G Setbp1 SET binding protein 1 JBrowse link NW_004936517 1,616,169 1,798,002 RGD:9068941
Blast Crisis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aicda activation induced cytidine deaminase JBrowse link NW_004936870 25,039 34,601 RGD:9068941
G Bcr BCR activator of RhoGEF and GTPase JBrowse link NW_004936619 288,377 432,297 RGD:9068941
G Esr2 estrogen receptor 2 JBrowse link NW_004936495 7,956,168 8,018,356 RGD:9068941
G Hmox1 heme oxygenase 1 JBrowse link NW_004936492 5,042,353 5,049,216 RGD:9068941
G Tcn2 transcobalamin 2 JBrowse link NW_004936904 97,535 113,886 RGD:9068941
chronic myeloid leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1 ATP binding cassette subfamily B member 1 JBrowse link NW_004936763 1,225,355 1,308,257 RGD:9068941
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link NW_004936636 292,631 341,999 RGD:9068941
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link NW_004936487 17,690,206 17,819,619 RGD:7240710
RGD:9068941
G Agt angiotensinogen JBrowse link NW_004936484 19,713,299 19,721,144 RGD:9068941
G Akt1 AKT serine/threonine kinase 1 JBrowse link NW_004936621 620,163 639,115 RGD:9068941
G Alox5 arachidonate 5-lipoxygenase JBrowse link NW_004936554 7,807,914 7,848,691 RGD:9068941
G Arntl aryl hydrocarbon receptor nuclear translocator like JBrowse link NW_004936528 5,167,611 5,239,128 RGD:9068941
G Bcl2l1 BCL2 like 1 JBrowse link NW_004936485 18,654,046 18,707,324 RGD:9068941
G Bcr BCR activator of RhoGEF and GTPase JBrowse link NW_004936619 288,377 432,297 RGD:7240710
RGD:9068941
G Birc5 baculoviral IAP repeat containing 5 JBrowse link NW_004936594 2,812,165 2,820,618 RGD:9068941
G Braf B-Raf proto-oncogene, serine/threonine kinase JBrowse link NW_004936592 4,728,371 4,833,830 RGD:9068941
G Ca9 carbonic anhydrase 9 JBrowse link NW_004936524 3,672,393 3,678,630 RGD:9068941
G Cd36 CD36 molecule JBrowse link NW_004936810 791,823 838,303 RGD:9068941
G Cd40 CD40 molecule JBrowse link NW_004936514 6,936,915 6,947,246 RGD:9068941
G Cdkn1b cyclin dependent kinase inhibitor 1B JBrowse link NW_004936587 4,573,166 4,578,480 RGD:9068941
G Chordc1 cysteine and histidine rich domain containing 1 JBrowse link NW_004936893 644,977 661,651 RGD:9068941
G Crkl CRK like proto-oncogene, adaptor protein JBrowse link NW_004936619 2,447,686 2,479,589 RGD:9068941
G Cry1 cryptochrome circadian regulator 1 JBrowse link NW_004936492 7,929,138 7,994,797 RGD:9068941
G Cry2 cryptochrome circadian regulator 2 JBrowse link NW_004936562 3,133,849 3,168,472 RGD:9068941
G Csf3r colony stimulating factor 3 receptor JBrowse link NW_004936474 18,877,036 18,887,574 RGD:9068941
G Dnmt1 DNA methyltransferase 1 JBrowse link NW_004936659 520,181 565,496 RGD:9068941
G Dnmt3a DNA methyltransferase 3 alpha JBrowse link NW_004936493 6,963,406 7,013,256 RGD:9068941
G Dnmt3b DNA methyltransferase 3 beta JBrowse link NW_004936485 19,547,836 19,570,716 RGD:9068941
G E2f1 E2F transcription factor 1 JBrowse link NW_004936561 6,894,827 6,901,058 RGD:9068941
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link NW_004936706 1,816,561 1,829,638 RGD:9068941
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link NW_004936527 5,024,077 5,069,152 RGD:9068941
G Fas Fas cell surface death receptor JBrowse link NW_004936735 209,369 234,582 RGD:9068941
G Faslg Fas ligand JBrowse link NW_004936481 14,789,547 14,795,780 RGD:9068941
G Gab2 GRB2 associated binding protein 2 JBrowse link NW_004936498 6,775,170 6,835,680 RGD:9068941
G Gpx1 glutathione peroxidase 1 JBrowse link NW_004936529 997,943 999,123 RGD:9068941
G Gstp1 glutathione S-transferase pi 1 JBrowse link NW_004936599 2,197,681 2,200,642 RGD:9068941
G Hes1 hes family bHLH transcription factor 1 JBrowse link NW_004936711 640,002 642,580 RGD:9068941
G Hmmr hyaluronan mediated motility receptor JBrowse link NW_004936515 570,112 599,400 RGD:9068941
G Hmox1 heme oxygenase 1 JBrowse link NW_004936492 5,042,353 5,049,216 RGD:9068941
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link NW_004936487 13,348,465 13,352,717 RGD:9068941
G Il10 interleukin 10 JBrowse link NW_004936557 5,834,874 5,838,502 RGD:9068941
G Il1b interleukin 1 beta JBrowse link NW_004936783 1,251,678 1,256,807 RGD:9068941
G Il1rn interleukin 1 receptor antagonist JBrowse link NW_004936783 1,447,158 1,466,331 RGD:9068941
G Insl6 insulin like 6 JBrowse link NW_004936503 67,933 78,496 RGD:9068941
G Jak2 Janus kinase 2 JBrowse link NW_004936503 111,722 243,627 RGD:9068941
G Kit KIT proto-oncogene, receptor tyrosine kinase JBrowse link NW_004936482 17,162,854 17,238,319 RGD:9068941
G LOC101968921 angiotensin-converting enzyme JBrowse link NW_004936541 4,157,847 4,178,156 RGD:9068941
G LOC101969148 cytochrome P450 1A1 JBrowse link NW_004936471 33,682,730 33,688,332 RGD:9068941
G Mapk14 mitogen-activated protein kinase 14 JBrowse link NW_004936476 23,237,762 23,310,211 RGD:9068941
G Mdm2 MDM2 proto-oncogene JBrowse link NW_004936545 6,709,903 6,732,334 RGD:9068941
G Mlf1 myeloid leukemia factor 1 JBrowse link NW_004936519 5,208,288 5,241,375 RGD:9068941
G Mthfr methylenetetrahydrofolate reductase JBrowse link NW_004936474 623,438 637,849 RGD:9068941
G Ncstn nicastrin JBrowse link NW_004936740 285,789 301,918 RGD:9068941
G Npm1 nucleophosmin 1 JBrowse link NW_004936609 3,712,628 3,725,635 RGD:9068941
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link NW_004936475 19,771,384 19,785,034 RGD:9068941
G Nras NRAS proto-oncogene, GTPase JBrowse link NW_004936627 73,413 82,590 RGD:9068941
G Pecam1 platelet and endothelial cell adhesion molecule 1 JBrowse link NW_004936541 4,873,459 4,919,787 RGD:9068941
G Per1 period circadian regulator 1 JBrowse link NW_004936595 1,366,883 1,382,138 RGD:9068941
G Per2 period circadian regulator 2 JBrowse link NW_004936525 221,601 263,284 RGD:9068941
G Per3 period circadian regulator 3 JBrowse link NW_004936623 2,291,211 2,362,693 RGD:9068941
G Prame preferentially expressed antigen in melanoma JBrowse link NW_004936619 1,748,337 1,751,748 RGD:9068941
G Setbp1 SET binding protein 1 JBrowse link NW_004936517 1,616,169 1,798,002 RGD:9068941
G Sh2b3 SH2B adaptor protein 3 JBrowse link NW_004936558 4,103,898 4,126,883 RGD:9068941
G Sipa1 signal-induced proliferation-associated 1 JBrowse link NW_004936599 3,813,350 3,825,319 RGD:9068941
G Smad4 SMAD family member 4 JBrowse link NW_004936497 12,242,869 12,278,012 RGD:9068941
G Srsf1 serine and arginine rich splicing factor 1 JBrowse link NW_004936490 5,055,258 5,059,118 RGD:9068941
G Tert telomerase reverse transcriptase JBrowse link NW_004936815 468,987 492,666 RGD:9068941
G Tgfb1 transforming growth factor beta 1 JBrowse link NW_004936661 3,742,080 3,758,266 RGD:9068941
G Vegfa vascular endothelial growth factor A JBrowse link NW_004936476 16,245,134 16,261,180 RGD:9068941
G Wt1 WT1 transcription factor JBrowse link NW_004936533 5,411,949 5,459,693 RGD:9068941
G Xrcc1 X-ray repair cross complementing 1 JBrowse link NW_004936706 752,571 783,746 RGD:9068941
chronic myelomonocytic leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asxl1 ASXL transcriptional regulator 1 JBrowse link NW_004936485 19,218,494 19,297,188 RGD:9068941
G Csf3r colony stimulating factor 3 receptor JBrowse link NW_004936474 18,877,036 18,887,574 RGD:9068941
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link NW_004936527 5,024,077 5,069,152 RGD:9068941
G Kdm6a lysine demethylase 6A JBrowse link NW_004936502 10,980,303 11,196,711 RGD:9068941
G Nras NRAS proto-oncogene, GTPase JBrowse link NW_004936627 73,413 82,590 RGD:9068941
G Tet2 tet methylcytosine dioxygenase 2 JBrowse link NW_004936752 440,137 577,339 RGD:9068941
Chronic Myeloproliferative Disorder with Eosinophilia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdgfrb platelet derived growth factor receptor beta JBrowse link NW_004936504 4,762,251 4,799,789 RGD:7240710
RGD:9068941
chronic neutrophilic leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Csf3r colony stimulating factor 3 receptor JBrowse link NW_004936474 18,877,036 18,887,574 RGD:9068941
essential thrombocythemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atg2b autophagy related 2B JBrowse link NW_004936604 583,391 641,217 RGD:9068941
G Bdkrb1 bradykinin receptor B1 JBrowse link NW_004936604 551,774 567,014 RGD:9068941
G Bdkrb2 bradykinin receptor B2 JBrowse link NW_004936604 548,844 551,031 RGD:9068941
G Calr calreticulin JBrowse link NW_004936659 1,994,695 1,999,070 RGD:7240710
RGD:9068941
G Cd36 CD36 molecule JBrowse link NW_004936810 791,823 838,303 RGD:9068941
G Cd40lg CD40 ligand JBrowse link NW_004936513 10,607,617 10,620,403 RGD:9068941
G CUNH14orf132 chromosome unknown C14orf132 homolog JBrowse link NW_004936604 386,940 433,477 RGD:9068941
G Fgf2 fibroblast growth factor 2 JBrowse link NW_004936662 1,886,176 1,928,998 RGD:9068941
G Gskip GSK3B interacting protein JBrowse link NW_004936604 657,602 675,702 RGD:9068941
G Jak2 Janus kinase 2 JBrowse link NW_004936503 111,722 243,627 RGD:9068941
G Mpl MPL proto-oncogene, thrombopoietin receptor JBrowse link NW_004936474 24,744,673 24,757,189 RGD:9068941
G Myb MYB proto-oncogene, transcription factor JBrowse link NW_004936560 2,797,943 2,828,813 RGD:9068941
G Pdgfa platelet derived growth factor subunit A JBrowse link NW_004936754 808,894 828,554 RGD:9068941
G Pdgfb platelet derived growth factor subunit B JBrowse link NW_004936492 2,353,840 2,368,573 RGD:9068941
G Sh2b3 SH2B adaptor protein 3 JBrowse link NW_004936558 4,103,898 4,126,883 RGD:7240710
RGD:9068941
G Tcl1a T cell leukemia/lymphoma 1A JBrowse link NW_004936604 127,841 131,056 RGD:9068941
G Tgfb1 transforming growth factor beta 1 JBrowse link NW_004936661 3,742,080 3,758,266 RGD:9068941
G Thpo thrombopoietin JBrowse link NW_004936578 5,508,669 5,515,984 RGD:7240710
RGD:9068941
G Vcam1 vascular cell adhesion molecule 1 JBrowse link NW_004936748 785,491 802,791 RGD:9068941
G Vwf von Willebrand factor JBrowse link NW_004936709 1,578,137 1,741,877 RGD:9068941
familial chronic myelocytic leukemia-like syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Irf8 interferon regulatory factor 8 JBrowse link NW_004936641 2,608,109 2,622,446 RGD:9068941
Familial Myelofibrosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata1 GATA binding protein 1 JBrowse link NW_004936721 742,862 750,843 RGD:9068941
G Mpl MPL proto-oncogene, thrombopoietin receptor JBrowse link NW_004936474 24,744,673 24,757,189 RGD:9068941
G Vps45 vacuolar protein sorting 45 homolog JBrowse link NW_004936580 380,794 435,115 RGD:9068941
juvenile myelomonocytic leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akap12 A-kinase anchoring protein 12 JBrowse link NW_004936489 4,237,466 4,258,408 RGD:9068941
G Arhgap26 Rho GTPase activating protein 26 JBrowse link NW_004936504 11,106,030 11,531,854 RGD:7240710
RGD:9068941
G Asxl1 ASXL transcriptional regulator 1 JBrowse link NW_004936485 19,218,494 19,297,188 RGD:9068941
G Cbl Cbl proto-oncogene JBrowse link NW_004936542 4,136,389 4,235,746 RGD:7240710
RGD:9068941
G Csf2 colony stimulating factor 2 JBrowse link NW_004936647 3,081,896 3,083,864 RGD:9068941
G Dnmt3a DNA methyltransferase 3 alpha JBrowse link NW_004936493 6,963,406 7,013,256 RGD:9068941
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link NW_004936527 5,024,077 5,069,152 RGD:9068941
G Flt3 fms related tyrosine kinase 3 JBrowse link NW_004936472 23,169,967 23,239,178 RGD:9068941
G Gata2 GATA binding protein 2 JBrowse link NW_004936798 406,258 414,785 RGD:9068941
G Jak3 Janus kinase 3 JBrowse link NW_004936596 3,212,593 3,224,426 RGD:9068941
G Kras KRAS proto-oncogene, GTPase JBrowse link NW_004936548 2,078,568 2,113,877 RGD:9068941
G Nf1 neurofibromin 1 JBrowse link NW_004936538 3,394,623 3,596,025 RGD:7240710
RGD:9068941
G Nras NRAS proto-oncogene, GTPase JBrowse link NW_004936627 73,413 82,590 RGD:9068941
G Ptpn11 protein tyrosine phosphatase non-receptor type 11 JBrowse link NW_004936668 2,602,261 2,687,903 RGD:7240710
RGD:9068941
G Rac2 Rac family small GTPase 2 JBrowse link NW_004936492 3,726,375 3,737,961 RGD:9068941
G Rras RAS related JBrowse link NW_004936664 3,456,681 3,460,537 RGD:9068941
G Rras2 RAS related 2 JBrowse link NW_004936528 4,413,436 4,429,166 RGD:9068941
G Runx1 RUNX family transcription factor 1 JBrowse link NW_004936500 7,621,328 7,710,909 RGD:9068941
G Setbp1 SET binding protein 1 JBrowse link NW_004936517 1,616,169 1,798,002 RGD:9068941
G Sh2b3 SH2B adaptor protein 3 JBrowse link NW_004936558 4,103,898 4,126,883 RGD:9068941
G Zrsr2 zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2 JBrowse link NW_004936470 5,233,798 5,258,266 RGD:9068941
Leukemoid Reaction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Jak3 Janus kinase 3 JBrowse link NW_004936596 3,212,593 3,224,426 RGD:9068941
multiple myeloma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoe apolipoprotein E JBrowse link NW_004936706 1,512,438 1,516,805 RGD:9068941
G B2m beta-2-microglobulin JBrowse link NW_004936471 7,646,504 7,655,656 RGD:9068941
G Bcl2 BCL2 apoptosis regulator JBrowse link NW_004936497 2,209,136 2,373,580 RGD:9068941
G Bcl2l1 BCL2 like 1 JBrowse link NW_004936485 18,654,046 18,707,324 RGD:9068941
G Bcl2l10 BCL2 like 10 JBrowse link NW_004936471 13,943,600 13,946,085 RGD:9068941
G Bnip3 BCL2 interacting protein 3 JBrowse link NW_004936486 18,449,371 18,460,435 RGD:9068941
G Braf B-Raf proto-oncogene, serine/threonine kinase JBrowse link NW_004936592 4,728,371 4,833,830 RGD:9068941
G Btg1 BTG anti-proliferation factor 1 JBrowse link NW_004936507 8,789,952 8,797,247 RGD:9068941
G Cbl Cbl proto-oncogene JBrowse link NW_004936542 4,136,389 4,235,746 RGD:9068941
G Cbx7 chromobox 7 JBrowse link NW_004936492 2,411,171 2,428,484 RGD:9068941
G Ccnd2 cyclin D2 JBrowse link NW_004936606 4,474,801 4,496,158 RGD:9068941
G Ccnd3 cyclin D3 JBrowse link NW_004936476 17,799,754 17,886,835 RGD:9068941
G Cd40 CD40 molecule JBrowse link NW_004936514 6,936,915 6,947,246 RGD:9068941
G Cd40lg CD40 ligand JBrowse link NW_004936513 10,607,617 10,620,403 RGD:9068941
G Cd46 CD46 molecule JBrowse link NW_004936557 5,136,784 5,175,543 RGD:9068941
G Cd86 CD86 molecule JBrowse link NW_004936536 8,414,491 8,481,712 RGD:9068941
G Cdk4 cyclin dependent kinase 4 JBrowse link NW_004936646 1,886,262 1,889,260 RGD:9068941
G Chi3l1 chitinase 3 like 1 JBrowse link NW_004936567 1,411,080 1,418,332 RGD:9068941
G Crbn cereblon JBrowse link NW_004936577 2,834,134 2,854,116 RGD:9068941
G Csf2 colony stimulating factor 2 JBrowse link NW_004936647 3,081,896 3,083,864 RGD:9068941
G Csf3 colony stimulating factor 3 JBrowse link NW_004936490 15,142,526 15,146,375 RGD:9068941
G Ctla4 cytotoxic T-lymphocyte associated protein 4 JBrowse link NW_004936631 484,356 489,643 RGD:9068941
G Eng endoglin JBrowse link NW_004936487 15,467,165 15,499,180 RGD:9068941
G Ephx1 epoxide hydrolase 1 JBrowse link NW_004936526 2,589,254 2,652,831 RGD:9068941
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link NW_004936706 1,854,938 1,867,521 RGD:9068941
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link NW_004936706 1,816,561 1,829,638 RGD:9068941
G Faslg Fas ligand JBrowse link NW_004936481 14,789,547 14,795,780 RGD:9068941
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link NW_004936477 21,591,772 21,606,289 RGD:9068941
G Fgg fibrinogen gamma chain JBrowse link NW_004936576 1,343,657 1,352,085 RGD:9068941
G Flt3lg fms related tyrosine kinase 3 ligand JBrowse link NW_004936664 3,343,541 3,351,590 RGD:9068941
G Gpx1 glutathione peroxidase 1 JBrowse link NW_004936529 997,943 999,123 RGD:9068941
G Gstp1 glutathione S-transferase pi 1 JBrowse link NW_004936599 2,197,681 2,200,642 RGD:9068941
G Hfe homeostatic iron regulator JBrowse link NW_004936671 1,940,079 1,947,574 RGD:9068941
G Hk1 hexokinase 1 JBrowse link NW_004936521 9,067,062 9,139,112 RGD:9068941
G Hras HRas proto-oncogene, GTPase JBrowse link NW_004936888 375,372 378,125 RGD:9068941
G Hspb1 heat shock protein family B (small) member 1 JBrowse link NW_004936543 2,110,351 2,111,896 RGD:9068941
G Icam1 intercellular adhesion molecule 1 JBrowse link NW_004936659 616,570 627,172 RGD:9068941
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 JBrowse link NW_004936950 334,894 349,221 RGD:9068941
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 JBrowse link NW_004936483 15,845,777 15,864,341 RGD:9068941
G Il10 interleukin 10 JBrowse link NW_004936557 5,834,874 5,838,502 RGD:9068941
G Il1a interleukin 1 alpha JBrowse link NW_004936783 1,210,715 1,218,315 RGD:9068941
G Il1b interleukin 1 beta JBrowse link NW_004936783 1,251,678 1,256,807 RGD:9068941
G Il1rn interleukin 1 receptor antagonist JBrowse link NW_004936783 1,447,158 1,466,331 RGD:9068941
G Il4r interleukin 4 receptor JBrowse link NW_004936501 11,025,590 11,058,807 RGD:9068941
G Irf4 interferon regulatory factor 4 JBrowse link NW_004936633 1,565,293 1,580,859 RGD:9068941
G Kras KRAS proto-oncogene, GTPase JBrowse link NW_004936548 2,078,568 2,113,877 RGD:9068941
G Lig4 DNA ligase 4 JBrowse link NW_004936472 3,861,833 3,867,943 RGD:7240710
RGD:9068941
G LOC101968921 angiotensin-converting enzyme JBrowse link NW_004936541 4,157,847 4,178,156 RGD:9068941
G LOC101969148 cytochrome P450 1A1 JBrowse link NW_004936471 33,682,730 33,688,332 RGD:9068941
G LOC101974817 E3 SUMO-protein ligase RanBP2 JBrowse link NW_004936829 261,017 333,910 RGD:9068941
G Lrrc56 leucine rich repeat containing 56 JBrowse link NW_004936888 379,622 397,647 RGD:9068941
G Mcl1 MCL1 apoptosis regulator, BCL2 family member JBrowse link NW_004936580 803,452 806,966 RGD:9068941
G Mefv MEFV innate immuity regulator, pyrin JBrowse link NW_004936694 970,706 980,605 RGD:9068941
G Met MET proto-oncogene, receptor tyrosine kinase JBrowse link NW_004936589 2,280,803 2,390,179 RGD:9068941
G Mthfr methylenetetrahydrofolate reductase JBrowse link NW_004936474 623,438 637,849 RGD:9068941
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase JBrowse link NW_004936484 16,087,924 16,180,089 RGD:9068941
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase JBrowse link NW_004936643 379,790 410,034 RGD:9068941
G Muc1 mucin 1, cell surface associated JBrowse link NW_004936580 4,691,870 4,694,092 RGD:9068941
G Myd88 MYD88 innate immune signal transduction adaptor JBrowse link NW_004936473 27,672,237 27,676,339 RGD:9068941
G Nfkbia NFKB inhibitor alpha JBrowse link NW_004936494 9,537,793 9,541,187 RGD:9068941
G Notch2 notch receptor 2 JBrowse link NW_004936872 454,273 539,544 RGD:9068941
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link NW_004936475 19,771,384 19,785,034 RGD:9068941
G Nras NRAS proto-oncogene, GTPase JBrowse link NW_004936627 73,413 82,590 RGD:9068941
G Nuak1 NUAK family kinase 1 JBrowse link NW_004936492 8,710,039 8,774,870 RGD:9068941
G Parp1 poly(ADP-ribose) polymerase 1 JBrowse link NW_004936526 3,102,468 3,147,601 RGD:9068941
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link NW_004936566 3,924,013 3,951,052 RGD:9068941
G Pon1 paraoxonase 1 JBrowse link NW_004936585 4,954,871 4,979,560 RGD:9068941
G Prame preferentially expressed antigen in melanoma JBrowse link NW_004936619 1,748,337 1,751,748 RGD:9068941
G Psors1c2 psoriasis susceptibility 1 candidate 2 JBrowse link NW_004936837 806,668 808,585 RGD:9068941
G Pthlh parathyroid hormone like hormone JBrowse link NW_004936760 197,525 209,212 RGD:9068941
G Ptpn11 protein tyrosine phosphatase non-receptor type 11 JBrowse link NW_004936668 2,602,261 2,687,903 RGD:9068941
G Runx1 RUNX family transcription factor 1 JBrowse link NW_004936500 7,621,328 7,710,909 RGD:9068941
G Sod2 superoxide dismutase 2 JBrowse link NW_004936489 11,178,338 11,191,601 RGD:9068941
G Sparc secreted protein acidic and cysteine rich JBrowse link NW_004936515 11,026,156 11,046,812 RGD:9068941
G Spp1 secreted phosphoprotein 1 JBrowse link NW_004936905 148,956 156,023 RGD:9068941
G Tert telomerase reverse transcriptase JBrowse link NW_004936815 468,987 492,666 RGD:9068941
G Tfrc transferrin receptor JBrowse link NW_004936784 696,738 728,385 RGD:9068941
G Tgfb1 transforming growth factor beta 1 JBrowse link NW_004936661 3,742,080 3,758,266 RGD:9068941
G Tnf tumor necrosis factor JBrowse link NW_004936727 1,936,066 1,937,766 RGD:9068941
G Tnfrsf13b TNF receptor superfamily member 13B JBrowse link NW_004936741 626,814 637,317 RGD:9068941
G Tnfrsf17 TNF receptor superfamily member 17 JBrowse link NW_004936501 907,059 910,084 RGD:9068941
G Tp53 tumor protein p53 JBrowse link NW_004936595 919,807 935,367 RGD:9068941
G Tyms thymidylate synthetase JBrowse link NW_004936550 33,797 42,233 RGD:9068941
G Ulk4 unc-51 like kinase 4 JBrowse link NW_004936473 30,034,159 30,536,450 RGD:9068941
G Vegfa vascular endothelial growth factor A JBrowse link NW_004936476 16,245,134 16,261,180 RGD:9068941
G Xpo5 exportin 5 JBrowse link NW_004936476 16,434,629 16,481,044 RGD:9068941
G Xrcc4 X-ray repair cross complementing 4 JBrowse link NW_004936469 2,248,367 2,495,215 RGD:9068941
G Xrcc5 X-ray repair cross complementing 5 JBrowse link NW_004936586 1,055,478 1,137,924 RGD:9068941
myelodysplastic/myeloproliferative neoplasm term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddx41 DEAD-box helicase 41 JBrowse link NW_004936597 1,787,830 1,793,352 RGD:9068941
G Dido1 death inducer-obliterator 1 JBrowse link NW_004936514 10,370,961 10,422,484 RGD:9068941
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link NW_004936527 5,024,077 5,069,152 RGD:9068941
myelofibrosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asxl1 ASXL transcriptional regulator 1 JBrowse link NW_004936485 19,218,494 19,297,188 RGD:9068941
G Atg2b autophagy related 2B JBrowse link NW_004936604 583,391 641,217 RGD:9068941
G Bdkrb1 bradykinin receptor B1 JBrowse link NW_004936604 551,774 567,014 RGD:9068941
G Bdkrb2 bradykinin receptor B2 JBrowse link NW_004936604 548,844 551,031 RGD:9068941
G Calr calreticulin JBrowse link NW_004936659 1,994,695 1,999,070 RGD:7240710
RGD:9068941
G CUNH14orf132 chromosome unknown C14orf132 homolog JBrowse link NW_004936604 386,940 433,477 RGD:9068941
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link NW_004936706 1,854,938 1,867,521 RGD:9068941
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit JBrowse link NW_004936706 1,816,561 1,829,638 RGD:9068941
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link NW_004936527 5,024,077 5,069,152 RGD:9068941
G Flt3 fms related tyrosine kinase 3 JBrowse link NW_004936472 23,169,967 23,239,178 RGD:9068941
G Flt3lg fms related tyrosine kinase 3 ligand JBrowse link NW_004936664 3,343,541 3,351,590 RGD:9068941
G Gata1 GATA binding protein 1 JBrowse link NW_004936721 742,862 750,843 RGD:9068941
G Gskip GSK3B interacting protein JBrowse link NW_004936604 657,602 675,702 RGD:9068941
G Hfe homeostatic iron regulator JBrowse link NW_004936671 1,940,079 1,947,574 RGD:9068941
G Insl6 insulin like 6 JBrowse link NW_004936503 67,933 78,496 RGD:9068941
G Jak2 Janus kinase 2 JBrowse link NW_004936503 111,722 243,627 RGD:7240710
RGD:9068941
G Mpl MPL proto-oncogene, thrombopoietin receptor JBrowse link NW_004936474 24,744,673 24,757,189 RGD:7240710
RGD:9068941
G Myb MYB proto-oncogene, transcription factor JBrowse link NW_004936560 2,797,943 2,828,813 RGD:9068941
G Ncor2 nuclear receptor corepressor 2 JBrowse link NW_004936558 658,723 775,263 RGD:9068941
G Sh2b3 SH2B adaptor protein 3 JBrowse link NW_004936558 4,103,898 4,126,883 RGD:7240710
RGD:9068941
G Tcl1a T cell leukemia/lymphoma 1A JBrowse link NW_004936604 127,841 131,056 RGD:9068941
G Tgfb1 transforming growth factor beta 1 JBrowse link NW_004936661 3,742,080 3,758,266 RGD:9068941
G Tp53 tumor protein p53 JBrowse link NW_004936595 919,807 935,367 RGD:9068941
Myeloid Leukemia, Chronic-Phase term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link NW_004936487 17,690,206 17,819,619 RGD:9068941
G Bcr BCR activator of RhoGEF and GTPase JBrowse link NW_004936619 288,377 432,297 RGD:9068941
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link NW_004936706 1,854,938 1,867,521 RGD:9068941
G Gfi1 growth factor independent 1 transcriptional repressor JBrowse link NW_004936537 6,610,565 6,618,509 RGD:9068941
G Gfi1b growth factor independent 1B transcriptional repressor JBrowse link NW_004936487 19,414,135 19,417,465 RGD:9068941
myeloproliferative neoplasm term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Csf3r colony stimulating factor 3 receptor JBrowse link NW_004936474 18,877,036 18,887,574 RGD:9068941
G Ddx41 DEAD-box helicase 41 JBrowse link NW_004936597 1,787,830 1,793,352 RGD:9068941
G Etv6 ETS variant 6 JBrowse link NW_004936587 5,328,467 5,457,260 RGD:9068941
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link NW_004936477 21,591,772 21,606,289 RGD:9068941
G Insl6 insulin like 6 JBrowse link NW_004936503 67,933 78,496 RGD:9068941
G Jak2 Janus kinase 2 JBrowse link NW_004936503 111,722 243,627 RGD:9068941
G Jak3 Janus kinase 3 JBrowse link NW_004936596 3,212,593 3,224,426 RGD:9068941
G Kit KIT proto-oncogene, receptor tyrosine kinase JBrowse link NW_004936482 17,162,854 17,238,319 RGD:9068941
G Mpl MPL proto-oncogene, thrombopoietin receptor JBrowse link NW_004936474 24,744,673 24,757,189 RGD:9068941
G Pdgfrb platelet derived growth factor receptor beta JBrowse link NW_004936504 4,762,251 4,799,789 RGD:9068941
G Tet2 tet methylcytosine dioxygenase 2 JBrowse link NW_004936752 440,137 577,339 RGD:9068941
Noonan Syndrome-Like Disorder with or without Juvenile Myelomonocytic Leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbl Cbl proto-oncogene JBrowse link NW_004936542 4,136,389 4,235,746 RGD:7240710
RGD:9068941
G Ptpn11 protein tyrosine phosphatase non-receptor type 11 JBrowse link NW_004936668 2,602,261 2,687,903 RGD:9068941
plasmacytic leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd40 CD40 molecule JBrowse link NW_004936514 6,936,915 6,947,246 RGD:9068941
G Tert telomerase reverse transcriptase JBrowse link NW_004936815 468,987 492,666 RGD:9068941
polycythemia vera term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2l1 BCL2 like 1 JBrowse link NW_004936485 18,654,046 18,707,324 RGD:9068941
G Cd36 CD36 molecule JBrowse link NW_004936810 791,823 838,303 RGD:9068941
G Epor erythropoietin receptor JBrowse link NW_004936659 1,468,391 1,473,880 RGD:9068941
G Gsr glutathione-disulfide reductase JBrowse link NW_004936792 531,076 579,083 RGD:9068941
G Hfe homeostatic iron regulator JBrowse link NW_004936671 1,940,079 1,947,574 RGD:9068941
G Insl6 insulin like 6 JBrowse link NW_004936503 67,933 78,496 RGD:9068941
G Jak1 Janus kinase 1 JBrowse link NW_004936692 2,298,149 2,354,084 RGD:9068941
G Jak2 Janus kinase 2 JBrowse link NW_004936503 111,722 243,627 RGD:7240710
RGD:9068941
Thrombocythemia 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mpl MPL proto-oncogene, thrombopoietin receptor JBrowse link NW_004936474 24,744,673 24,757,189 RGD:7240710
RGD:9068941
Thrombocythemia 3 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Insl6 insulin like 6 JBrowse link NW_004936503 67,933 78,496 RGD:9068941
G Jak2 Janus kinase 2 JBrowse link NW_004936503 111,722 243,627 RGD:7240710
RGD:9068941
Thrombocytopenia, Anemia, and Myelofibrosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mpig6b megakaryocyte and platelet inhibitory receptor G6b JBrowse link NW_004936727 1,808,317 1,811,058 RGD:7240710
RGD:9068941
thrombocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Calr calreticulin JBrowse link NW_004936659 1,994,695 1,999,070 RGD:9068941
G Cpb2 carboxypeptidase B2 JBrowse link NW_004936857 577,067 609,855 RGD:9068941
G Epor erythropoietin receptor JBrowse link NW_004936659 1,468,391 1,473,880 RGD:9068941
G Il1b interleukin 1 beta JBrowse link NW_004936783 1,251,678 1,256,807 RGD:9068941
G Jak2 Janus kinase 2 JBrowse link NW_004936503 111,722 243,627 RGD:9068941
G Mpl MPL proto-oncogene, thrombopoietin receptor JBrowse link NW_004936474 24,744,673 24,757,189 RGD:9068941
G Thpo thrombopoietin JBrowse link NW_004936578 5,508,669 5,515,984 RGD:9068941
Thrombocytosis, Benign Familial Microcytic term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mpl MPL proto-oncogene, thrombopoietin receptor JBrowse link NW_004936474 24,744,673 24,757,189 RGD:9068941
transient myeloproliferative syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata1 GATA binding protein 1 JBrowse link NW_004936721 742,862 750,843 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 11337
    disease of anatomical entity 11005
      hematopoietic system disease 1237
        bone marrow disease 361
          myeloid neoplasm 196
            Acute Erythroblastic Leukemia + 13
            Chronic Myeloproliferative Disorder with Eosinophilia 1
            Leukemoid Reaction + 2
            Myeloproliferative Disease, Autosomal Recessive 0
            chronic myeloid leukemia + 73
            chronic neutrophilic leukemia 1
            multiple myeloma + 88
            myelodysplastic/myeloproliferative neoplasm + 28
            myelofibrosis + 25
            myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1 + 0
            myelophthisic anemia 0
            myeloproliferative neoplasm + 35
            thrombocytosis + 24
Path 2
Term Annotations click to browse term
  disease 11337
    disease of anatomical entity 11005
      Hemic and Lymphatic Diseases 1484
        hematopoietic system disease 1237
          Hematologic Neoplasms 696
            hematologic cancer 696
              bone marrow cancer 255
                myeloid neoplasm 196
                  Acute Erythroblastic Leukemia + 13
                  Chronic Myeloproliferative Disorder with Eosinophilia 1
                  Leukemoid Reaction + 2
                  Myeloproliferative Disease, Autosomal Recessive 0
                  chronic myeloid leukemia + 73
                  chronic neutrophilic leukemia 1
                  multiple myeloma + 88
                  myelodysplastic/myeloproliferative neoplasm + 28
                  myelofibrosis + 25
                  myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1 + 0
                  myelophthisic anemia 0
                  myeloproliferative neoplasm + 35
                  thrombocytosis + 24
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.