Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


Term:spermatogenic failure 5
go back to main search page
Accession:DOID:0070183 term browser browse the term
Definition:A male infertility characterized by autosomal recessive inheritance of large-headed, multiflagellar, polyploid spermatozoa that has_material_basis_in mutation in the AURKC gene on chromosome 19q13. (DO)
Synonyms:exact_synonym: Infertility Associated with Multi-Tailed Spermatozoa and Excessive DNA;   SPGF5;   infertility associated with multitailed spermatozoa and excessive DNA;   macrocephalic sperm head syndrome;   male infertility due to macrozoospermia;   male infertility with large-headed, multiflagellar, polyploid spermatozoa
 primary_id: MESH:C562903
 alt_id: OMIM:243060;   RDO:0012423
 xref: GARD:12385;   ORDO:137893
For additional species annotation, visit the Alliance of Genome Resources.

show annotations for term's descendants       view all columns           Sort by:
spermatogenic failure 5 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aurkc aurora kinase C JBrowse link 1 69,958,452 69,964,546 RGD:8554872

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14924
    Developmental Diseases 7770
      Congenital, Hereditary, and Neonatal Diseases and Abnormalities 7092
        genetic disease 6457
          spermatogenic failure 5 1
Path 2
Term Annotations click to browse term
  disease 14924
    disease of anatomical entity 14094
      Urogenital Diseases 3916
        Female Urogenital Diseases and Pregnancy Complications 1699
          Female Urogenital Diseases 1447
            female reproductive system disease 1443
              infertility 205
                male infertility 146
                  spermatogenic failure 5 1
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.