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Term:Worth syndrome
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Accession:DOID:0080037 term browser browse the term
Definition:A hyperostosis that has_material_basis_in a mutation in the LRP5 gene which results_in increased bone density and bony structures located_in palate. (DO)
Synonyms:exact_synonym: Hyperostosis Corticalis Generalisata, Benign Form Of Worth, With Torus Palatinus;   Osteosclerosis, autosomal dominant Worth type with torus palatinus;   Worth disease;   Worth's syndrome;   autosomal dominant endosteal hyperostosis;   autosomal dominant osteosclerosis;   autosomal dominant osteosclerosis, Worth type;   benign form of Worth hyperostosis corticalis generalisata with torus platinus;   benign hyperostosis corticalis generalisata;   endosteal hyperostosis, Worth type;   hyperostosis corticalis generalisata congenita;   osteosclerosis of the skull and enlarged mandible
 primary_id: MESH:C536748
 alt_id: DOID:0111372;   DOID:9001208;   MESH:C536527;   OMIM:144750;   OMIM:607636
 xref: GARD:390;   ORDO:2790
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Worth syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp5 LDL receptor related protein 5 JBrowse link 1 218,816,833 218,920,147 RGD:7240710

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16022
    syndrome 6143
      Worth syndrome 1
Path 2
Term Annotations click to browse term
  disease 16022
    disease of anatomical entity 15275
      Skin and Connective Tissue Diseases 5371
        connective tissue disease 4007
          bone disease 3471
            bone development disease 1263
              osteochondrodysplasia 430
                osteosclerosis 44
                  osteopetrosis 26
                    Worth syndrome 1
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.