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Accession:DOID:0111036 term browser browse the term
Definition:A CADASIL characterized by stroke, transient ischemic attacks, cognitive impairment, dementia, balance impairment, gait disturbance, headaches, and/or seizures associated with early confluent or confluent diffuse white matter hyperintensities that has_material_basis_in heterozygous mutation in the HTRA1 gene on chromosome 10q26. (DO)
Synonyms:exact_synonym: CADASIL2;   autosomal dominant cerebral arteriopathy with subcortical infarcts and leukoencephalopathy type 2
 primary_id: OMIM:616779
 xref: ICD10CM:F01.1
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CADASIL 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Htra1 HtrA serine peptidase 1 JBrowse link NW_004936486 11,271,130 11,317,271 RGD:7240710

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 0
    Diseases of the Aged 929
      dementia 593
        vascular dementia 37
          CADASIL 2
            CADASIL 2 1
Path 2
Term Annotations click to browse term
  disease 11879
    disease of anatomical entity 11444
      nervous system disease 9331
        central nervous system disease 7822
          brain disease 7189
            disease of mental health 5126
              cognitive disorder 1591
                dementia 593
                  vascular dementia 37
                    CADASIL 2
                      CADASIL 2 1
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