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Term:amyotrophic lateral sclerosis-parkinsonism/dementia complex 1
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Accession:DOID:0111246 term browser browse the term
Definition:A neurodegenerative disease characterized by chronic, progressive amyotrophic lateral sclerosis and parkinsonism-dementia. Susceptibility to this disease is influenced by heterozygous mutation in TRPM7 on 15q21.2. (DO)
Synonyms:exact_synonym: ALS-PDC;   AMYOTROPHIC LATERAL SCLEROSIS-PARKINSONISM/DEMENTIA COMPLEX OF GUAM;   Amyotrophic lateral sclerosis-parkinsonism-dementia of Guam syndrome;   GUAM DISEASE;   Guam PD;   Lytico-Bodig disease;   PDALS;   Parkinsonism-dementia of Guam;   parkinsonism-dementia-ALS complex
 primary_id: OMIM:105500
 alt_id: RDO:0007875
 xref: GARD:9239;   ORDO:90020
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amyotrophic lateral sclerosis-parkinsonism/dementia complex 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:8554872
G Trpm7 transient receptor potential cation channel, subfamily M, member 7 JBrowse link 3 119,258,189 119,347,084 RGD:5685005

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15992
    Diseases of the Aged 1219
      dementia 663
        amyotrophic lateral sclerosis-parkinsonism/dementia complex 1 2
Path 2
Term Annotations click to browse term
  disease 15992
    disease of anatomical entity 15263
      nervous system disease 10756
        peripheral nervous system disease 2359
          neuropathy 2174
            neuromuscular disease 1706
              motor neuron disease 363
                amyotrophic lateral sclerosis 214
                  amyotrophic lateral sclerosis-parkinsonism/dementia complex 1 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.