ONTOLOGY REPORT - ANNOTATIONS


Term:open-angle glaucoma
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Accession:DOID:1067 term browser browse the term
Definition:Glaucoma in which the angle of the anterior chamber is open and the trabecular meshwork does not encroach on the base of the iris.
Synonyms:exact_synonym: Compensated Glaucomas;   Compensative Glaucoma;   Compensative Glaucomas;   Glaucoma Simplex;   Open Angle Glaucomas;   Pigmentary Glaucoma;   Pigmentary Glaucomas;   Simple Glaucoma;   Simple Glaucomas;   compensated glaucoma;   glaucoma simplices;   wide-angle glaucoma
 primary_id: MESH:D005902
 alt_id: RDO:0005676
For additional species annotation, visit the Alliance of Genome Resources.


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open-angle glaucoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:8548468
G Afap1 actin filament associated protein 1 JBrowse link 14 79,923,132 80,035,096 RGD:13673886
G Apoc3 apolipoprotein C3 JBrowse link 8 50,529,318 50,531,498 RGD:10054092
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:7495786
G Asb10 ankyrin repeat and SOCS box-containing 10 JBrowse link 4 7,158,293 7,167,505 RGD:13592920
G Atxn2 ataxin 2 JBrowse link 12 40,264,601 40,335,637 RGD:11554173
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:11554173
G Cav2 caveolin 2 JBrowse link 4 44,573,264 44,580,640 RGD:11554173
G Cdkn2b cyclin-dependent kinase inhibitor 2B JBrowse link 5 107,834,353 107,857,428 RGD:8548689
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:8552673
G Fndc3b fibronectin type III domain containing 3B JBrowse link 2 113,109,949 113,415,171 RGD:11554173
G Foxc1 forkhead box C1 JBrowse link 17 33,947,501 33,951,484 RGD:11554173
G Gmds GDP-mannose 4, 6-dehydratase JBrowse link 17 33,408,722 33,938,086 RGD:13673886
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:7364852
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:5147910
G Mthfr methylenetetrahydrofolate reductase JBrowse link 5 164,844,642 164,864,360 RGD:7387252
RGD:7387254
G Myoc myocilin JBrowse link 13 80,517,531 80,527,928 RGD:7401194
RGD:11554173
G Ntf4 neurotrophin 4 JBrowse link 1 101,405,314 101,408,145 RGD:13592920
G Optn optineurin JBrowse link 17 77,167,700 77,218,374 RGD:1600995
RGD:11554173
RGD:6480513
RGD:6480510
RGD:6480509
G Pon1 paraoxonase 1 JBrowse link 4 30,249,749 30,276,297 RGD:8547552
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:11554173
G Tap1 transporter 1, ATP binding cassette subfamily B member JBrowse link 20 3,979,302 3,989,669 RGD:6482266
G Tmco1 transmembrane and coiled-coil domains 1 JBrowse link 13 85,465,015 85,559,113 RGD:11554173
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:7387247
G Txnrd2 thioredoxin reductase 2 JBrowse link 11 86,667,994 86,716,063 RGD:11554173
G Wdr36 WD repeat domain 36 JBrowse link 18 25,637,475 25,665,801 RGD:11554173
buphthalmos term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:7240710
RGD:8554872
RGD:7800719
RGD:7800711
RGD:7800707
RGD:7800689
RGD:7800688
RGD:7800680
RGD:7800670
RGD:7800657
RGD:734869
G Foxc1 forkhead box C1 JBrowse link 17 33,947,501 33,951,484 RGD:13592920
G Ltbp2 latent transforming growth factor beta binding protein 2 JBrowse link 6 108,500,114 108,596,653 RGD:8554872
G Myoc myocilin JBrowse link 13 80,517,531 80,527,928 RGD:8554872
G Tyr tyrosinase JBrowse link 1 151,012,598 151,106,802 RGD:13592920
Glaucoma 1, Open Angle, B term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fastkd1 FAST kinase domains 1 JBrowse link 3 55,925,598 55,951,584 RGD:8554872
Glaucoma 1, Open Angle, D term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:8554872
G Myoc myocilin JBrowse link 13 80,517,531 80,527,928 RGD:8554872
Glaucoma 1, Open Angle, E term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Optn optineurin JBrowse link 17 77,167,700 77,218,374 RGD:8554872
Glaucoma 1, Open Angle, F term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asb10 ankyrin repeat and SOCS box-containing 10 JBrowse link 4 7,158,293 7,167,505 RGD:7240710
RGD:8554872
Glaucoma 1, Open Angle, G term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wdr36 WD repeat domain 36 JBrowse link 18 25,637,475 25,665,801 RGD:7240710
RGD:8554872
Glaucoma 1, Open Angle, P term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tbk1 TANK-binding kinase 1 JBrowse link 7 63,655,247 63,687,978 RGD:8554872
hydrophthalmos term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:1599716
G Flt1 FMS-related tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:8549773
G Kdr kinase insert domain receptor JBrowse link 14 34,727,677 34,787,127 RGD:8549773
juvenile glaucoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Myoc myocilin JBrowse link 13 80,517,531 80,527,928 RGD:7240710
RGD:8554872
RGD:7401248
RGD:7401247
RGD:7401192
RGD:7401186
RGD:7394848
RGD:7394834
RGD:7394828
RGD:7394800
RGD:7394798
RGD:7394788
RGD:7394787
G Pax6 paired box 6 JBrowse link 3 95,700,241 95,728,682 RGD:13592920
low tension glaucoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:8548468
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:7495800
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:8655604
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:8661774
G Cav2 caveolin 2 JBrowse link 4 44,573,264 44,580,640 RGD:8661774
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:9491770
RGD:9491771
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:8661736
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:10402863
G Myoc myocilin JBrowse link 13 80,517,531 80,527,928 RGD:7771548
G Opa1 OPA1, mitochondrial dynamin like GTPase JBrowse link 11 74,717,600 74,793,902 RGD:13592920
G Optn optineurin JBrowse link 17 77,167,700 77,218,374 RGD:7771548
RGD:13592920
RGD:7775043
RGD:7775041
G Slc1a1 solute carrier family 1 member 1 JBrowse link 1 246,955,017 247,035,159 RGD:11554173
G Slc1a3 solute carrier family 1 member 3 JBrowse link 2 57,860,881 57,935,363 RGD:13592920
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:8655579
RGD:13592920
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:7794768
RGD:7794769
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:7775041
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:7387247
pigment dispersion syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col18a1 collagen type XVIII alpha 1 chain JBrowse link 20 12,225,202 12,332,858 RGD:13592920
G Gpnmb glycoprotein nmb JBrowse link 4 78,694,447 78,715,685 RGD:13592920
primary open angle glaucoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:8547563
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:8548468
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:7495787
RGD:7771556
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:8655612
G Camk1d calcium/calmodulin-dependent protein kinase ID JBrowse link 17 76,532,611 76,938,956 RGD:8554872
G Card10 caspase recruitment domain family, member 10 JBrowse link 7 119,998,639 120,028,632 RGD:8554872
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:8661770
RGD:8661783
RGD:8661776
G Cav2 caveolin 2 JBrowse link 4 44,573,264 44,580,640 RGD:8661770
G Ccdc3 coiled-coil domain containing 3 JBrowse link 17 76,991,722 77,093,515 RGD:8554872
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:8661807
RGD:8661806
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:7800658
RGD:8554872
RGD:7800696
RGD:7800695
RGD:7800664
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:8661676
G Eln elastin JBrowse link 12 24,978,478 25,021,864 RGD:9585735
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:8553056
RGD:8694092
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:7488947
RGD:7488948
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:7794820
RGD:7794825
RGD:7794823
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 JBrowse link 2 181,045,694 181,103,321 RGD:13592920
G Loxl1 lysyl oxidase-like 1 JBrowse link 8 63,067,757 63,092,124 RGD:7387330
RGD:7394723
G Ltbp2 latent transforming growth factor beta binding protein 2 JBrowse link 6 108,500,114 108,596,653 RGD:8554872
G Mbl2 mannose binding lectin 2 JBrowse link 1 248,435,069 248,442,669 RGD:8693705
G Mcm10 minichromosome maintenance 10 replication initiation factor JBrowse link 17 77,224,218 77,245,486 RGD:8554872
G Mmp1 matrix metallopeptidase 1 JBrowse link 8 5,703,206 5,723,593 RGD:8549724
RGD:8549725
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:8549725
G Myoc myocilin JBrowse link 13 80,517,531 80,527,928 RGD:1600842
RGD:8554872
RGD:7401171
RGD:7401254
RGD:7401251
RGD:7401245
RGD:7401240
RGD:7401189
RGD:7401175
RGD:7401170
RGD:7401168
RGD:7401164
RGD:7401163
RGD:7394843
RGD:7394841
RGD:7394816
RGD:7394814
RGD:7394801
RGD:7394792
RGD:7394791
RGD:7394789
RGD:1600838
RGD:1600840
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:7771542
RGD:7775055
RGD:7775039
RGD:7771575
RGD:7771573
RGD:7771543
G Ogg1 8-oxoguanine DNA glycosylase JBrowse link 4 145,282,828 145,289,367 RGD:8657152
G Opa1 OPA1, mitochondrial dynamin like GTPase JBrowse link 11 74,717,600 74,793,902 RGD:7800685
RGD:7800721
RGD:7800718
RGD:7800713
G Optn optineurin JBrowse link 17 77,167,700 77,218,374 RGD:7240710
RGD:8554872
RGD:7775049
RGD:7775043
RGD:7775041
G Pon1 paraoxonase 1 JBrowse link 4 30,249,749 30,276,297 RGD:8547563
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:8158079
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:7794768
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:7775041
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:8547822
G Wdr36 WD repeat domain 36 JBrowse link 18 25,637,475 25,665,801 RGD:8548463
RGD:8554872
RGD:8548466
RGD:8548465

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14875
    sensory system disease 4246
      eye and adnexa disease 1985
        eye disease 1985
          glaucoma 135
            open-angle glaucoma 66
              Glaucoma 1, Open Angle, B 1
              Glaucoma 1, Open Angle, C 0
              Glaucoma 1, Open Angle, D 2
              Glaucoma 1, Open Angle, E 1
              Glaucoma 1, Open Angle, F 1
              Glaucoma 1, Open Angle, G 1
              Glaucoma 1, Open Angle, H 0
              Glaucoma 1, Open Angle, I 0
              Glaucoma 1, Open Angle, J 0
              Glaucoma 1, Open Angle, K 0
              Glaucoma 1, Open Angle, M 0
              Glaucoma 1, Open Angle, N 0
              Glaucoma 1, Open Angle, P 1
              Glaucoma with Elevated Episcleral Venous Pressure 0
              hydrophthalmos + 8
              low tension glaucoma 17
              pigment dispersion syndrome 2
              primary open angle glaucoma + 35
              residual stage of open angle glaucoma 0
Path 2
Term Annotations click to browse term
  disease 14875
    disease of anatomical entity 14051
      cardiovascular system disease 4056
        vascular disease 3039
          artery disease 1963
            hypertension 1452
              ocular hypertension 151
                glaucoma 135
                  open-angle glaucoma 66
                    Glaucoma 1, Open Angle, B 1
                    Glaucoma 1, Open Angle, C 0
                    Glaucoma 1, Open Angle, D 2
                    Glaucoma 1, Open Angle, E 1
                    Glaucoma 1, Open Angle, F 1
                    Glaucoma 1, Open Angle, G 1
                    Glaucoma 1, Open Angle, H 0
                    Glaucoma 1, Open Angle, I 0
                    Glaucoma 1, Open Angle, J 0
                    Glaucoma 1, Open Angle, K 0
                    Glaucoma 1, Open Angle, M 0
                    Glaucoma 1, Open Angle, N 0
                    Glaucoma 1, Open Angle, P 1
                    Glaucoma with Elevated Episcleral Venous Pressure 0
                    hydrophthalmos + 8
                    low tension glaucoma 17
                    pigment dispersion syndrome 2
                    primary open angle glaucoma + 35
                    residual stage of open angle glaucoma 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.