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ONTOLOGY REPORT - ANNOTATIONS


Term:Henoch-Schoenlein purpura
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Accession:DOID:11123 term browser browse the term
Definition:A systemic non-thrombocytopenic purpura caused by HYPERSENSITIVITY VASCULITIS and deposition of IGA-containing IMMUNE COMPLEXES within the blood vessels throughout the body, including those in the kidney (KIDNEY GLOMERULUS). Clinical symptoms include URTICARIA; ERYTHEMA; ARTHRITIS; GASTROINTESTINAL HEMORRHAGE; and renal involvement. Most cases are seen in children after acute upper respiratory infections.
Synonyms:exact_synonym: Anaphylactoid Purpura;   HSP;   Hemorrhagic Vasculitis;   Henoch Purpura;   Henoch Schonlein Purpura;   Henoch Schonlein Purpuras;   Henoch-Sch@nlein purpura;   Henoch-Scholein purpura;   IgA vasculitis;   IgAV;   Nonthrombocytopenic Purpura;   Nonthrombopenic Purpura;   Nonthrombopenic Purpuras;   Purpura Hemorrhagica;   Purpura, autoimmune;   allergic purpura;   rheumatoid purpura
 narrow_synonym: Henoch-Schoenlein purpura nephritis
 primary_id: MESH:D011695
 alt_id: RDO:0003056
 xref: GARD:8204;   NCI:C34963
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Henoch-Schoenlein purpura term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACE angiotensin I converting enzyme JBrowse link 9 11,497,182 11,516,362 RGD:9068941
G AGT angiotensinogen JBrowse link 4 8,681,192 8,694,059 RGD:9068941
G C3 complement C3 JBrowse link 20 53,566,226 53,598,365 RGD:9068941
G CCL2 C-C motif chemokine ligand 2 JBrowse link 9 39,008,187 39,009,932 RGD:9068941
G CD86 CD86 molecule JBrowse link 33 25,256,267 25,318,855 RGD:9068941
G HMOX1 heme oxygenase 1 JBrowse link 10 28,744,404 28,751,544 RGD:9068941
G IGF1 insulin like growth factor 1 JBrowse link 15 41,203,320 41,275,964 RGD:9068941
G IL1RN interleukin 1 receptor antagonist JBrowse link 17 37,236,690 37,250,424 RGD:9068941
G IL5 interleukin 5 JBrowse link 11 20,825,469 20,827,269 RGD:9068941
G KNG1 kininogen 1 JBrowse link 34 19,288,629 19,318,096 RGD:9068941
G MEFV MEFV innate immuity regulator, pyrin JBrowse link 6 37,964,776 37,984,830 RGD:9068941
G PLAT plasminogen activator, tissue type JBrowse link 16 23,469,590 23,496,013 RGD:9068941
G PLAU plasminogen activator, urokinase JBrowse link 4 24,329,139 24,333,893 RGD:9068941
G PON1 paraoxonase 1 JBrowse link 14 20,565,620 20,600,774 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 11436
    disease of anatomical entity 10904
      immune system disease 2045
        hypersensitivity reaction disease 1271
          hypersensitivity reaction type III disease 24
            Henoch-Schoenlein purpura 14
              Vascular Purpura 0
Path 2
Term Annotations click to browse term
  disease 11436
    disease of anatomical entity 10904
      Immune & Inflammatory Diseases 2523
        immune system disease 2045
          hypersensitivity reaction disease 1271
            allergic hypersensitivity disease 524
              hypersensitivity reaction type III disease 24
                hypersensitivity vasculitis 15
                  Henoch-Schoenlein purpura 14
                    Vascular Purpura 0
paths to the root

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