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ONTOLOGY REPORT - ANNOTATIONS


Term:Henoch-Schoenlein purpura
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Accession:DOID:11123 term browser browse the term
Definition:A systemic non-thrombocytopenic purpura caused by HYPERSENSITIVITY VASCULITIS and deposition of IGA-containing IMMUNE COMPLEXES within the blood vessels throughout the body, including those in the kidney (KIDNEY GLOMERULUS). Clinical symptoms include URTICARIA; ERYTHEMA; ARTHRITIS; GASTROINTESTINAL HEMORRHAGE; and renal involvement. Most cases are seen in children after acute upper respiratory infections.
Synonyms:exact_synonym: Anaphylactoid Purpura;   HSP;   Hemorrhagic Vasculitis;   Henoch Purpura;   Henoch Schonlein Purpura;   Henoch Schonlein Purpuras;   Henoch-Sch@nlein purpura;   Henoch-Scholein purpura;   IgA vasculitis;   IgAV;   Nonthrombocytopenic Purpura;   Nonthrombopenic Purpura;   Nonthrombopenic Purpuras;   Purpura Hemorrhagica;   Purpura, autoimmune;   allergic purpura;   rheumatoid purpura
 narrow_synonym: Henoch-Schoenlein purpura nephritis
 primary_id: MESH:D011695
 alt_id: RDO:0003056
 xref: GARD:8204;   NCI:C34963
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Henoch-Schoenlein purpura term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACE angiotensin I converting enzyme JBrowse link 17 63,477,061 63,498,380 RGD:11038920
G AGT angiotensinogen JBrowse link 1 230,702,523 230,714,590 RGD:11039045
RGD:11039055
G C3 complement C3 JBrowse link 19 6,677,835 6,720,682 RGD:11554173
G CCL2 C-C motif chemokine ligand 2 JBrowse link 17 34,255,277 34,257,203 RGD:11522500
RGD:11528567
G CD86 CD86 molecule JBrowse link 3 122,055,362 122,121,143 RGD:11354986
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 JBrowse link 6 32,637,406 32,654,846 RGD:5147830
G HMOX1 heme oxygenase 1 JBrowse link 22 35,381,067 35,394,214 RGD:10755701
G IGF1 insulin like growth factor 1 JBrowse link 12 102,395,860 102,481,839 RGD:10755701
G IL1RN interleukin 1 receptor antagonist JBrowse link 2 113,099,365 113,134,016 RGD:6909151
G IL5 interleukin 5 JBrowse link 5 132,539,194 132,556,864 RGD:11354946
G KNG1 kininogen 1 JBrowse link 3 186,717,309 186,744,410 RGD:11059888
G MEFV MEFV innate immuity regulator, pyrin JBrowse link 16 3,242,028 3,256,776 RGD:7349346
RGD:11531116
RGD:7349347
G PLAT plasminogen activator, tissue type JBrowse link 8 42,174,718 42,207,724 RGD:11541055
G PLAU plasminogen activator, urokinase JBrowse link 10 73,909,182 73,917,501 RGD:11554173
G PON1 paraoxonase 1 JBrowse link 7 95,297,676 95,324,706 RGD:11552576

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15698
    disease of anatomical entity 14467
      immune system disease 2349
        hypersensitivity reaction disease 1501
          hypersensitivity reaction type III disease 26
            Henoch-Schoenlein purpura 15
              Vascular Purpura 0
Path 2
Term Annotations click to browse term
  disease 15698
    disease of anatomical entity 14467
      Immune & Inflammatory Diseases 2869
        immune system disease 2349
          hypersensitivity reaction disease 1501
            allergic hypersensitivity disease 608
              hypersensitivity reaction type III disease 26
                hypersensitivity vasculitis 16
                  Henoch-Schoenlein purpura 15
                    Vascular Purpura 0
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