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Term:Adie syndrome
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Accession:DOID:11549 term browser browse the term
Definition:A syndrome characterized by a TONIC PUPIL that occurs in combination with decreased lower extremity reflexes. The affected pupil will respond more briskly to accommodation than to light (light-near dissociation) and is supersensitive to dilute pilocarpine eye drops, which induce pupillary constriction. Pathologic features include degeneration of the ciliary ganglion and postganglionic parasympathetic fibers that innervate the pupillary constrictor muscle. (From Adams et al., Principles of Neurology, 6th ed, p279)
Synonyms:exact_synonym: Adie's Syndrome;   Adie's pupil or syndrome;   Adie's pupil syndrome;   Holmes Adie Syndrome;   Poorly Reacting Pupil;   Poorly Reacting Pupils;   tonic, sluggishly reacting pupil and hypoactive or absent tendon reflexes
 primary_id: MESH:C531601;   MESH:D000270
 alt_id: OMIM:103100;   RDO:0000015;   RDO:0000016
 xref: GARD:5749;   NCI:C34357
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Path 1
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  disease 15602
    syndrome 5231
      Adie syndrome 0
Path 2
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  disease 15602
    disease of anatomical entity 14933
      nervous system disease 10260
        sensory system disease 4697
          eye and adnexa disease 2268
            eye disease 2268
              ocular motility disease 114
                third cranial nerve disease 2
                  Adie syndrome 0
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