ONTOLOGY REPORT - ANNOTATIONS


Term:hepatorenal syndrome
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Accession:DOID:11823 term browser browse the term
Definition:Functional KIDNEY FAILURE in patients with liver disease, usually LIVER CIRRHOSIS or portal hypertension (HYPERTENSION, PORTAL), and in the absence of intrinsic renal disease or kidney abnormality. It is characterized by intense renal vasculature constriction, reduced renal blood flow, OLIGURIA, and sodium retention.
Synonyms:primary_id: MESH:D006530;   RDO:0005786
 xref: GARD:6610
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hepatorenal syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:11554173
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:11554173
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:1581228
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:4144102
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:4144102

Term paths to the root
Path 1
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  disease 14823
    syndrome 4218
      hepatorenal syndrome 5
Path 2
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  disease 14823
    disease of anatomical entity 13997
      Urogenital Diseases 3777
        urinary system disease 2009
          kidney disease 1805
            kidney failure 454
              acute kidney failure 275
                hepatorenal syndrome 5
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.