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ONTOLOGY REPORT - ANNOTATIONS


Term:anterior ischemic optic neuropathy
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Accession:DOID:12010 term browser browse the term
Definition:Ischemic injury to the OPTIC NERVE which usually affects the OPTIC DISK (optic neuropathy, anterior ischemic) and less frequently the retrobulbar portion of the nerve (optic neuropathy, posterior ischemic). The injury results from occlusion of arterial blood supply which may result from TEMPORAL ARTERITIS; ATHEROSCLEROSIS; COLLAGEN DISEASES; EMBOLISM; DIABETES MELLITUS; and other conditions. The disease primarily occurs in the sixth decade or later and presents with the sudden onset of painless and usually severe monocular visual loss. Anterior ischemic optic neuropathy also features optic disk edema with microhemorrhages. The optic disk appears normal in posterior ischemic optic neuropathy. (Glaser, Neuro-Ophthalmology, 2nd ed, p135)
Synonyms:exact_synonym: Ischemic Optic Neuropathies;   Optic Nerve Ischemia;   Optic Nerve Ischemias;   Posterior Ischemic Optic Neuropathy;   ischemic optic neuropathy
 primary_id: MESH:D018917;   RDO:0007244
 xref: GARD:9790
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anterior ischemic optic neuropathy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Becn1 beclin 1 JBrowse link 10 89,209,944 89,225,297 RGD:6483070
G Csf3 colony stimulating factor 3 JBrowse link 10 86,616,785 86,619,160 RGD:11039419
G Mt-nd1 mitochondrially encoded NADH dehydrogenase 1 JBrowse link MT 2,740 3,694 RGD:5490236
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:7775040
non-arteritic anterior ischemic optic neuropathy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ace angiotensin I converting enzyme JBrowse link 10 94,170,766 94,213,831 RGD:8548899
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:9491785
G F5 coagulation factor V JBrowse link 13 82,479,997 82,535,540 RGD:7394764
G Gp1ba glycoprotein Ib platelet subunit alpha JBrowse link 10 57,260,680 57,263,546 RGD:8554872
RGD:11554173
RGD:7240710
G Itgb3 integrin subunit beta 3 JBrowse link 10 92,667,869 92,783,413 RGD:8693343
G Mthfr methylenetetrahydrofolate reductase JBrowse link 5 164,844,642 164,864,360 RGD:8693343

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15590
    disease of anatomical entity 14919
      cardiovascular system disease 4229
        vascular disease 3278
          anterior ischemic optic neuropathy 10
            arteritic anterior ischemic optic neuropathy 0
            non-arteritic anterior ischemic optic neuropathy 6
Path 2
Term Annotations click to browse term
  disease 15590
    disease of anatomical entity 14919
      nervous system disease 10196
        sensory system disease 4659
          eye and adnexa disease 2236
            eye disease 2236
              optic nerve disease 191
                anterior ischemic optic neuropathy 10
                  arteritic anterior ischemic optic neuropathy 0
                  non-arteritic anterior ischemic optic neuropathy 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.