ONTOLOGY REPORT - ANNOTATIONS


Term:trigeminal neuralgia
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Accession:DOID:12098 term browser browse the term
Definition:A syndrome characterized by recurrent episodes of excruciating pain lasting several seconds or longer in the sensory distribution of the TRIGEMINAL NERVE. Pain may be initiated by stimulation of trigger points on the face, lips, or gums or by movement of facial muscles or chewing. Associated conditions include MULTIPLE SCLEROSIS, vascular anomalies, ANEURYSMS, and neoplasms. (Adams et al., Principles of Neurology, 6th ed, p187)
Synonyms:exact_synonym: Fothergill disease;   Idiopathic Trigeminal Neuralgia;   Idiopathic Trigeminal Neuralgias;   Secondary Trigeminal Neuralgia;   Secondary Trigeminal Neuralgias;   Tic Douloureux;   Trifacial Neuralgia;   epileptiform neuralgia;   epileptiform neuralgias;   trifacial neuralgias;   trifocal neuralgia;   trigeminal neuralgias
 primary_id: MESH:D014277
 alt_id: OMIM:190400;   RDO:0006750
 xref: GARD:7805
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trigeminal neuralgia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aif1 allograft inflammatory factor 1 JBrowse link 20 5,161,350 5,167,176 RGD:11554173
G Calca calcitonin-related polypeptide alpha JBrowse link 1 184,184,018 184,188,922 RGD:11554173
G Cdk5 cyclin-dependent kinase 5 JBrowse link 4 7,282,945 7,287,427 RGD:13782378
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 JBrowse link 10 67,862,054 67,863,255 RGD:13782378
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:11554173
G Gfap glial fibrillary acidic protein JBrowse link 10 90,990,762 90,999,435 RGD:11554173
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 JBrowse link 3 2,507,745 2,534,664 RGD:11554173
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:11554173
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:11554173
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:11554173
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:11554173
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 10 35,333,859 35,374,364 RGD:11554173
G Prkcg protein kinase C, gamma JBrowse link 1 64,407,098 64,433,698 RGD:11554173
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:11554173

Term paths to the root
Path 1
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  disease 14920
    syndrome 4714
      trigeminal neuralgia 14
Path 2
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  disease 14920
    disease of anatomical entity 14086
      nervous system disease 9150
        peripheral nervous system disease 2017
          neuropathy 1838
            cranial nerve disease 360
              facial nerve disease 49
                facial neuralgia 15
                  trigeminal nerve disease 15
                    trigeminal neuralgia 14
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.