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ONTOLOGY REPORT - ANNOTATIONS


Term:malaria
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Accession:DOID:12365 term browser browse the term
Definition:A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
Synonyms:exact_synonym: MALARIA, MILD, SUSCEPTIBILITY TO;   MALS;   Marsh Fever;   Paludism;   Plasmodium Infection;   Plasmodium Infections;   Plasmodium Vivax, Resistance To;   Remittent Fever;   Susceptibility To Malaria;   induced malaria
 narrow_synonym: MALARIA, CEREBRAL, RESISTANCE TO;   MALARIA, CEREBRAL, SUSCEPTIBILITY TO;   MALARIA, RESISTANCE TO;   MALARIA, SEVERE, RESISTANCE TO;   MALARIA, SEVERE, SUSCEPTIBILITY TO
 related_synonym: DUFFY BLOOD GROUP SYSTEM, FY(a-b-) PHENOTYPE;   Glycophorin C, Gerbich Variant
 primary_id: MESH:D008288;   RDO:0000157
 alt_id: OMIM:609148;   OMIM:611162
 xref: GARD:6961;   ICD10CM:B54;   ICD9CM:084;   ICD9CM:084.6;   NCI:C34797
For additional species annotation, visit the Alliance of Genome Resources.


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malaria term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ackr1 atypical chemokine receptor 1 JBrowse link 13 91,827,310 91,828,875 RGD:8554872
RGD:11554173
RGD:7240710
G Ank1 ankyrin 1 JBrowse link 16 73,681,422 73,912,605 RGD:13592920
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:11039486
G Aqp4 aquaporin 4 JBrowse link 18 6,766,009 6,782,757 RGD:13592920
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:8554872
RGD:11554173
RGD:7240710
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:11352239
G Cd40lg CD40 ligand JBrowse link X 159,703,703 159,714,886 RGD:11352239
G Cish cytokine inducible SH2-containing protein JBrowse link 8 116,054,547 116,059,494 RGD:8554872
RGD:11554173
RGD:7240710
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:11554173
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:5147921
RGD:11554173
RGD:7240710
RGD:8554872
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:8554872
RGD:11554173
RGD:7240710
G G6pd glucose-6-phosphate dehydrogenase JBrowse link X 156,274,800 156,293,935 RGD:10449111
RGD:8554872
RGD:11554173
RGD:7240710
RGD:10449115
G Gypc glycophorin C (Gerbich blood group) JBrowse link 18 25,312,386 25,344,614 RGD:8554872
RGD:11554173
RGD:7240710
G Hbb hemoglobin subunit beta JBrowse link 1 168,971,269 168,972,680 RGD:1600894
RGD:8554872
RGD:11554173
RGD:7240710
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:13592920
G Hp haptoglobin JBrowse link 19 42,096,255 42,100,805 RGD:11554173
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:8554872
RGD:11554173
RGD:7240710
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:13592920
G Ltbr lymphotoxin beta receptor JBrowse link 4 157,822,838 157,829,291 RGD:11554173
G Mapkapk3 MAPK activated protein kinase 3 JBrowse link 8 116,012,126 116,046,012 RGD:8554872
G Mki67 marker of proliferation Ki-67 JBrowse link 1 207,993,895 208,020,454 RGD:6483517
G Ncr3 natural cytotoxicity triggering receptor 3 JBrowse link 20 5,170,169 5,175,773 RGD:8554872
RGD:11554173
RGD:7240710
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:8554872
RGD:11554173
RGD:7240710
G Pklr pyruvate kinase L/R JBrowse link 2 188,449,158 188,458,034 RGD:11535999
RGD:13592920
RGD:11537407
G Prf1 perforin 1 JBrowse link 20 30,915,294 30,920,804 RGD:6482803
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) JBrowse link 10 90,296,144 90,312,401 RGD:8554872
RGD:11554173
RGD:7240710
G Spp1 secreted phosphoprotein 1 JBrowse link 14 6,673,686 6,679,965 RGD:1581333
G Tirap TIR domain containing adaptor protein JBrowse link 8 36,382,029 36,399,625 RGD:8554872
RGD:7240710
RGD:11554173
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624967
RGD:11554173
RGD:7240710
RGD:8554872
cerebral malaria term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aqp4 aquaporin 4 JBrowse link 18 6,766,009 6,782,757 RGD:8698661
G Cast calpastatin JBrowse link 2 1,452,111 1,561,669 RGD:5509817
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:6893527
G Jak3 Janus kinase 3 JBrowse link 16 20,107,471 20,120,678 RGD:11531103
G Lta lymphotoxin alpha JBrowse link 20 4,851,889 4,854,677 RGD:10449455
G Tnfrsf1b TNF receptor superfamily member 1B JBrowse link 5 163,136,390 163,167,299 RGD:5131158
Malarial Anemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcgr3a Fc fragment of IgG receptor IIIa JBrowse link 13 89,385,775 89,396,047 RGD:11040771
RGD:11344971
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) JBrowse link 10 90,296,144 90,312,401 RGD:10450507
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:11344971
Plasmodium falciparum malaria term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adamts13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 JBrowse link 3 5,519,921 5,558,390 RGD:10449041
G Cast calpastatin JBrowse link 2 1,452,111 1,561,669 RGD:5509812
G Ccl4 C-C motif chemokine ligand 4 JBrowse link 10 70,870,926 70,886,357 RGD:5683898
G Clec11a C-type lectin domain containing 11A JBrowse link 1 100,290,374 100,293,515 RGD:11554173
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:11554173
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:5147927
G G6pd glucose-6-phosphate dehydrogenase JBrowse link X 156,274,800 156,293,935 RGD:10449113
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:10450848
G Hbb hemoglobin subunit beta JBrowse link 1 168,971,269 168,972,680 RGD:11554173
G Hp haptoglobin JBrowse link 19 42,096,255 42,100,805 RGD:11041793
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:5684362
G Mbl2 mannose binding lectin 2 JBrowse link 1 248,435,069 248,442,669 RGD:11530064
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:11041780
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:10450571
Plasmodium vivax malaria term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ackr1 atypical chemokine receptor 1 JBrowse link 13 91,827,310 91,828,875 RGD:8554872
Pregnancy-associated Malaria term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:11041890

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15489
    disease by infectious agent 830
      parasitic infectious disease 193
        parasitic protozoa infectious disease 112
          malaria 44
            Acute Malaria 0
            Avian Malaria 0
            Malarial Anemia 3
            Plasmodium Falciparum Blood Infection Level 0
            Plasmodium falciparum malaria + 15
            Plasmodium malariae malaria 0
            Plasmodium ovale malaria 0
            Plasmodium vivax malaria 1
            blackwater fever 0
            cerebral malaria 6
            mixed malaria 0
Path 2
Term Annotations click to browse term
  disease 15489
    disease of anatomical entity 14790
      Immune & Inflammatory Diseases 3125
        Inflammation 2040
          Systemic Inflammatory Response Syndrome 309
            Sepsis 307
              Parasitemia 44
                malaria 44
                  Acute Malaria 0
                  Avian Malaria 0
                  Malarial Anemia 3
                  Plasmodium Falciparum Blood Infection Level 0
                  Plasmodium falciparum malaria + 15
                  Plasmodium malariae malaria 0
                  Plasmodium ovale malaria 0
                  Plasmodium vivax malaria 1
                  blackwater fever 0
                  cerebral malaria 6
                  mixed malaria 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.