ONTOLOGY REPORT - ANNOTATIONS


Term:Guillain-Barre syndrome
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Accession:DOID:12842 term browser browse the term
Definition:An acute inflammatory autoimmune neuritis caused by T cell- mediated cellular immune response directed towards peripheral myelin. Demyelination occurs in peripheral nerves and nerve roots. The process is often preceded by a viral or bacterial infection, surgery, immunization, lymphoma, or exposure to toxins. Common clinical manifestations include progressive weakness, loss of sensation, and loss of deep tendon reflexes. Weakness of respiratory muscles and autonomic dysfunction may occur. (From Adams et al., Principles of Neurology, 6th ed, pp1312-1314)
Synonyms:exact_synonym: Acute Autoimmune Neuropathies;   Acute Autoimmune Neuropathy;   Acute Infectious Polyneuritis;   Acute Inflammatory Demyelinating Polyradiculoneuropathy;   Acute Inflammatory Polyneuropathies;   Acute Inflammatory Polyneuropathy;   Acute Inflammatory Polyradiculoneuropathies;   Acute Inflammatory Polyradiculoneuropathy;   GBS;   Guillain-Barre Syndrome, Familial;   Guillain-Barré Syndrome;   Guillaine Barre Syndrome;   Inflammatory Polyneuropathy Acutes;   Landry Guillain Barre Syndrome;   Post-infectious polyneuritis;   acute infective polyneuritis;   acute postinfectious polyneuropathy;   infectious neuronitis;   postinfectious polyneuritis
 narrow_synonym: AIDP POLYNEUROPATHY, INFLAMMATORY DEMYELINATING, CHRONIC;   CIDP;   POLYNEUROPATHY, INFLAMMATORY DEMYELINATING, ACUTE
 primary_id: MESH:D020275
 alt_id: OMIM:139393;   RDO:0007295
 xref: GARD:6554
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Guillain-Barre syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aire autoimmune regulator JBrowse link 20 11,365,630 11,380,636 RGD:13592920
G Apoa4 apolipoprotein A4 JBrowse link 8 50,536,983 50,539,371 RGD:5685658
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:8549645
G Cd86 CD86 molecule JBrowse link 11 67,060,305 67,117,990 RGD:13592920
G Cst3 cystatin C JBrowse link 3 143,219,671 143,223,544 RGD:5686395
G Ctsb cathepsin B JBrowse link 15 46,316,741 46,337,613 RGD:5686395
G Gdnf glial cell derived neurotrophic factor JBrowse link 2 56,884,181 56,912,964 RGD:6218983
G Hcrt hypocretin neuropeptide precursor JBrowse link 10 88,669,216 88,670,430 RGD:1600925
G Pmp22 peripheral myelin protein 22 JBrowse link 10 49,538,588 49,568,583 RGD:7240710
RGD:8554872

Term paths to the root
Path 1
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  disease 14875
    syndrome 4220
      Guillain-Barre syndrome 16
        Miller Fisher syndrome 0
Path 2
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  disease 14875
    disease of anatomical entity 14051
      Immune & Inflammatory Diseases 2988
        immune system disease 2414
          hypersensitivity reaction disease 1456
            autoimmune hypersensitivity disease 1162
              autoimmune disease of the nervous system 403
                autoimmune disease of peripheral nervous system 46
                  Guillain-Barre syndrome 16
                    Miller Fisher syndrome 0
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