ONTOLOGY REPORT - ANNOTATIONS


Term:retinopathy of prematurity
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Accession:DOID:13025 term browser browse the term
Definition:A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)
Synonyms:exact_synonym: Prematurity Retinopathies;   Prematurity Retinopathy;   Retrolental Fibroplasia;   Retrolental Fibroplasias;   premature retinopathy
 primary_id: MESH:D012178;   RDO:0006483
 xref: GARD:5695
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retinopathy of prematurity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb3 adrenoceptor beta 3 JBrowse link 16 69,003,541 69,006,632 RGD:5684355
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:11554173
G Angpt2 angiopoietin 2 JBrowse link 16 75,966,480 76,016,147 RGD:2314205
RGD:2314207
G Epo erythropoietin JBrowse link 12 22,274,828 22,278,268 RGD:11041658
G Epor erythropoietin receptor JBrowse link 8 22,969,737 22,974,468 RGD:11041658
G Flt1 FMS-related tyrosine kinase 1 JBrowse link 12 9,033,993 9,205,886 RGD:5684426
G Fzd4 frizzled class receptor 4 JBrowse link 1 153,589,471 153,598,376 RGD:8554872
G Hgf hepatocyte growth factor JBrowse link 4 15,435,460 15,505,377 RGD:8548546
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:4145427
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:8548825
RGD:8548867
RGD:8548852
G Igfbp3 insulin-like growth factor binding protein 3 JBrowse link 14 87,457,647 87,465,374 RGD:12743584
G Ihh Indian hedgehog signaling molecule JBrowse link 9 82,208,223 82,214,440 RGD:12910978
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:7364863
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:7204128
G Kdr kinase insert domain receptor JBrowse link 14 34,727,677 34,787,127 RGD:5684426
RGD:8549753
RGD:8549746
G Ndp norrin cystine knot growth factor NDP JBrowse link X 6,791,090 6,815,586 RGD:8694210
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:7257667
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:7257667
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:7771560
G Prss23 serine protease 23 JBrowse link 1 153,732,528 153,742,111 RGD:8554872
G RT1-CE13 RT1 class I, locus CE13 RGD:7365093
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:7365093
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:8547810
G Serpinf1 serpin family F member 1 JBrowse link 10 62,241,750 62,254,145 RGD:8655555
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:8655635
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:8548546
Oxygen-Induced Retinopathy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:7394795
G Amigo2 adhesion molecule with Ig like domain 2 JBrowse link 7 138,704,124 138,707,221 RGD:14392781
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:8548878
RGD:11526145
G Csnk2a1 casein kinase 2 alpha 1 JBrowse link 3 147,713,808 147,760,375 RGD:11565123
G Csnk2a2 casein kinase 2 alpha 2 JBrowse link 19 9,972,537 10,012,043 RGD:11565123
G Csnk2b casein kinase 2 beta JBrowse link 20 5,108,692 5,113,675 RGD:11565123
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:12903974
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:12903974
G Ghrl ghrelin and obestatin prepropeptide JBrowse link 4 145,674,157 145,678,066 RGD:12904963
G Ghsr growth hormone secretagogue receptor JBrowse link 2 113,065,953 113,071,265 RGD:12904963
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:8695923
RGD:9068455
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:10402057
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:12910457
G Kdr kinase insert domain receptor JBrowse link 14 34,727,677 34,787,127 RGD:8549715
RGD:1581593
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:10412674
G Ndp norrin cystine knot growth factor NDP JBrowse link X 6,791,090 6,815,586 RGD:8694208
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:2301844
G Ptafr platelet-activating factor receptor JBrowse link 5 150,746,284 150,775,675 RGD:10041062
G Ptger3 prostaglandin E receptor 3 JBrowse link 2 263,895,093 263,979,682 RGD:9850261
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:8547749
RGD:13208592
G Serpinf1 serpin family F member 1 JBrowse link 10 62,241,750 62,254,145 RGD:8554878
RGD:8655544
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:8655606
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:8694296
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:7394799
RGD:7394795
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:7483624

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14823
    sensory system disease 4244
      eye and adnexa disease 1985
        eye disease 1985
          retinal disease 719
            retinopathy of prematurity 44
              Oxygen-Induced Retinopathy 25
Path 2
Term Annotations click to browse term
  disease 14823
    disease of anatomical entity 13997
      nervous system disease 9111
        sensory system disease 4244
          eye and adnexa disease 1985
            eye disease 1985
              retinal disease 719
                retinopathy of prematurity 44
                  Oxygen-Induced Retinopathy 25
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.