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Term:Sneddon syndrome
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Accession:DOID:13096 term browser browse the term
Definition:A systemic non-inflammatory arteriopathy primarily of middle-aged females characterized by the association of livedo reticularis, multiple thrombotic CEREBRAL INFARCTION; CORONARY DISEASE, and HYPERTENSION. Elevation of antiphospholipid antibody titers (see also ANTIPHOSPHOLIPID SYNDROME), cardiac valvulopathy, ISCHEMIC ATTACK, TRANSIENT; SEIZURES; DEMENTIA; and chronic ischemia of the extremities may also occur. Pathologic examination of affected arteries reveals non-inflammatory adventitial fibrosis, thrombosis, and changes in the media. (From Jablonski, Dictionary of Syndromes & Eponymic Diseases, 2d ed; Adams et al., Principles of Neurology, 6th ed, p861; Arch Neurol 1997 Jan;54(1):53-60)
Synonyms:exact_synonym: Livedo Reticularis And Cerebrovascular Accidents;   Sneddon Champion syndrome;   idiopathic livedo reticularis with systemic involvement;   livedo reticularis, systemic involvement
 primary_id: MESH:D018860
 alt_id: OMIM:182410;   RDO:0007238
 xref: GARD:7664
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  disease 14759
    syndrome 4210
      Sneddon syndrome 0
Path 2
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  disease 14759
    disease of anatomical entity 13978
      nervous system disease 9097
        central nervous system disease 6892
          brain disease 6396
            cerebrovascular disease 787
              Sneddon syndrome 0
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