Term:crescentic glomerulonephritis
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Accession:DOID:13139 term browser browse the term
Definition:A syndrome of the kidney that is characterized by a rapid loss of renal function involving severe injury to the kidneys' glomeruli, with many of the glomeruli containing characteristic glomerular crescents (crescent-shaped scars).
Synonyms:exact_synonym: RPGN;   rapidly progressive glomerulonephritis
 related_synonym: NCGN;   necrotizing crescentic glomerulonephritis
 primary_id: RDO:9000021
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crescentic glomerulonephritis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:8549743
G Ccl3 C-C motif chemokine ligand 3 JBrowse link 10 70,869,516 70,871,066 RGD:7241813
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:7248599
G Cd40lg CD40 ligand JBrowse link X 159,703,703 159,714,886 RGD:7248599
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:2293335
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:7175502
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:8551712
G Mmp12 matrix metallopeptidase 12 JBrowse link 8 5,594,717 5,616,494 RGD:2325762
G Mmp3 matrix metallopeptidase 3 JBrowse link 8 5,676,608 5,698,579 RGD:7241255
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:2313720
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:7245940
G Stat6 signal transducer and activator of transcription 6 JBrowse link 7 70,946,228 70,963,542 RGD:7243976
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:7246899

Term paths to the root
Path 1
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  disease 14875
    syndrome 4220
      crescentic glomerulonephritis 16
Path 2
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  disease 14875
    disease of anatomical entity 14051
      Urogenital Diseases 3874
        urinary system disease 2009
          kidney disease 1805
            nephritis 412
              glomerulonephritis 359
                acute proliferative glomerulonephritis 16
                  crescentic glomerulonephritis 16
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.