ONTOLOGY REPORT - ANNOTATIONS


Term:cerebral malaria
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Accession:DOID:14069 term browser browse the term
Definition:A condition characterized by somnolence or coma in the presence of an acute infection with PLASMODIUM FALCIPARUM (and rarely other Plasmodium species). Initial clinical manifestations include HEADACHES; SEIZURES; and alterations of mentation followed by a rapid progression to COMA. Pathologic features include cerebral capillaries filled with parasitized erythrocytes and multiple small foci of cortical and subcortical necrosis. (From Adams et al., Principles of Neurology, 6th ed, p136)
Synonyms:exact_synonym: Malaria Meningitis;   Malarial encephalitis
 primary_id: MESH:D016779;   RDO:0006997
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cerebral malaria term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aqp4 aquaporin 4 JBrowse link 18 6,766,009 6,782,757 RGD:8698661
G Cast calpastatin JBrowse link 2 1,452,111 1,561,669 RGD:5509817
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:6893527
G Jak3 Janus kinase 3 JBrowse link 16 20,107,471 20,120,678 RGD:11531103
G Lta lymphotoxin alpha JBrowse link 20 4,851,889 4,854,677 RGD:10449455
G Tnfrsf1b TNF receptor superfamily member 1B JBrowse link 5 163,136,390 163,167,299 RGD:5131158

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Path 1
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  disease 14919
    disease by infectious agent 808
      parasitic infectious disease 193
        Central Nervous System Parasitic Infections 9
          Central Nervous System Protozoal Infections 7
            cerebral malaria 7
Path 2
Term Annotations click to browse term
  disease 14919
    disease of anatomical entity 14083
      Immune & Inflammatory Diseases 3002
        Inflammation 2013
          Systemic Inflammatory Response Syndrome 307
            Sepsis 306
              Parasitemia 45
                malaria 45
                  cerebral malaria 7
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.