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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:alcoholic neuropathy
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Accession:DOID:14183 term browser browse the term
Definition:A condition where damage to the peripheral nervous system (including the peripheral elements of the autonomic nervous system) is associated with chronic ingestion of alcoholic beverages. The disorder may be caused by a direct effect of alcohol, an associated nutritional deficiency, or a combination of factors. Clinical manifestations include variable degrees of weakness; ATROPHY; PARESTHESIAS; pain; loss of reflexes; sensory loss; diaphoresis; and postural hypotension. (From Arch Neurol 1995;52(1):45-51; Adams et al., Principles of Neurology, 6th ed, p1146)
Synonyms:exact_synonym: Alcohol Induced Peripheral Neuropathy;   Alcohol Induced Polyneuropathy;   Alcohol Related Autonomic Polyneuropathy;   Alcohol Related Polyneuropathy;   Alcohol-Induced Peripheral Neuropathies;   Alcohol-Induced Polyneuropathies;   Alcohol-Related Autonomic Polyneuropathies;   Alcohol-Related Polyneuropathies;   Alcoholic Axonal Neuropathies;   Alcoholic Axonal Neuropathy;   Alcoholic Neuropathies;   Alcoholic Polyneuritides;   Alcoholic Polyneuritis;   Alcoholic Polyneuropathies;   Alcoholic Polyneuropathy
 primary_id: MESH:D020269
 alt_id: RDO:0007383
 xref: ICD10CM:G62.1;   ICD9CM:357.5;   NCI:C26926
For additional species annotation, visit the Alliance of Genome Resources.


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alcoholic neuropathy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igf1 insulin-like growth factor 1 IEP RGD PMID:23016131 RGD:10402569 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEP RGD PMID:23016131 RGD:10402569 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igf2 insulin-like growth factor 2 IEP RGD PMID:23016131 RGD:10402569 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16103
    syndrome 6989
      toxic encephalopathy 211
        Alcohol-Induced Disorders, Nervous System 63
          alcoholic neuropathy 3
Path 2
Term Annotations click to browse term
  disease 16103
    disease of anatomical entity 15351
      nervous system disease 10863
        central nervous system disease 9005
          brain disease 8328
            disease of mental health 5991
              substance-related disorder 615
                Alcohol-Related Disorders 289
                  Alcohol-Induced Disorders, Nervous System 63
                    alcoholic neuropathy 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.