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ONTOLOGY REPORT - ANNOTATIONS


Term:Parkinson's disease
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Accession:DOID:14330 term browser browse the term
Definition:A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
Synonyms:exact_synonym: Idiopathic Parkinson's Disease;   Lewy Body Parkinson Disease;   Lewy Body Parkinson's Disease;   PARKINSON DISEASE, DOMINANT/RECESSIVE;   PARKINSON'S DISEASE, DOMINANT;   PARKINSON'S DISEASE, DOMINANT/RECESSIVE;   PARKINSON'S DISEASE, RECESSIVE;   PARKINSON'S DISEASE, RESISTANCE TO;   Paralysis Agitans;   Parkinson Disease;   idiopathic Parkinson disease;   primary parkinsonism
 narrow_synonym: PARKINSON DISEASE, DOMINANT;   PARKINSON DISEASE, RECESSIVE;   PARKINSONISM/MELAS OVERLAP SYNDROME;   familial Parkinson's disease
 related_synonym: DOPAMINE BETA-HYDROXYLASE ACTIVITY, PLASMA;   PARKINSON DISEASE, AGE AT ONSET, SUSCEPTIBILITY TO;   PARKINSON DISEASE, RESISTANCE TO;   Parkinson Disease, Susceptibility To;   Parkinson's disease, susceptibility to
 primary_id: MESH:D010300
 alt_id: RDO:0002963
 xref: GARD:10251;   ICD9CM:332;   ICD9CM:332.0;   NCI:C26845;   OMIM:PS168600;   ORDO:2828
For additional species annotation, visit the Alliance of Genome Resources.


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Parkinson's disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCB1 ATP binding cassette subfamily B member 1 JBrowse link 14 13,644,891 13,852,829 RGD:9068941
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 9 53,118,462 53,262,092 RGD:9068941
G ACE angiotensin I converting enzyme JBrowse link 9 11,497,182 11,516,362 RGD:9068941
G ACHE acetylcholinesterase JBrowse link 6 8,874,747 8,879,926 RGD:9068941
G ADARB2 adenosine deaminase RNA specific B2 (inactive) JBrowse link 2 33,510,081 33,848,968 RGD:9068941
G ADCY5 adenylate cyclase 5 JBrowse link 33 26,345,617 26,490,120 RGD:9068941
G AFDN afadin, adherens junction formation factor JBrowse link 1 55,435,451 55,535,534 RGD:9068941
G AGTR1 angiotensin II receptor type 1 JBrowse link 23 43,569,658 43,617,113 RGD:9068941
G AIF1 allograft inflammatory factor 1 JBrowse link 12 1,104,350 1,106,179 RGD:9068941
G AKT1 AKT serine/threonine kinase 1 JBrowse link 8 72,317,399 72,335,686 RGD:9068941
G ANXA5 annexin A5 JBrowse link 19 18,419,936 18,450,088 RGD:9068941
G APAF1 apoptotic peptidase activating factor 1 JBrowse link 15 38,026,893 38,160,842 RGD:9068941
G APOA1 apolipoprotein A1 JBrowse link 5 16,740,071 16,742,081 RGD:9068941
G APOE apolipoprotein E JBrowse link 1 110,525,717 110,528,534 RGD:9068941
G ARPC3 actin related protein 2/3 complex subunit 3 JBrowse link 26 8,267,123 8,277,779 RGD:9068941
G ATG7 autophagy related 7 JBrowse link 20 6,916,354 7,154,849 RGD:9068941
G ATM ATM serine/threonine kinase JBrowse link 5 24,180,129 24,297,207 RGD:9068941
G ATP13A2 ATPase cation transporting 13A2 JBrowse link 2 81,196,355 81,215,736 RGD:9068941
G ATP6 ATP synthase F0 subunit 6 JBrowse link MT 7,964 8,644 RGD:9068941
G AUP1 AUP1 lipid droplet regulating VLDL assembly factor JBrowse link 17 48,613,648 48,617,091 RGD:9068941
G B2M beta-2-microglobulin JBrowse link 30 11,331,574 11,337,991 RGD:9068941
G BAG5 BAG cochaperone 5 JBrowse link 8 71,318,730 71,324,743 RGD:9068941
G BDNF brain derived neurotrophic factor JBrowse link 21 48,191,580 48,243,699 RGD:9068941
G BGLAP bone gamma-carboxyglutamate protein JBrowse link 7 41,630,092 41,630,976 RGD:9068941
G BST1 bone marrow stromal cell antigen 1 JBrowse link 3 64,617,903 64,641,131 RGD:9068941
G CASP3 caspase 3 JBrowse link 16 45,920,074 45,940,507 RGD:9068941
G CASP9 caspase 9 JBrowse link 2 82,033,759 82,076,710 RGD:9068941
G CAST calpastatin JBrowse link 3 12,920,514 13,031,974 RGD:9068941
G CCK cholecystokinin JBrowse link 23 11,414,254 11,419,990 RGD:9068941
G CCN2 cellular communication network factor 2 JBrowse link 1 25,508,082 25,511,058 RGD:9068941
G CNTNAP2 contactin associated protein 2 JBrowse link 16 2,239,953 4,208,718 RGD:9068941
G COL19A1 collagen type XIX alpha 1 chain JBrowse link 12 32,452,653 32,760,310 RGD:9068941
G COX10 cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 JBrowse link 5 37,853,495 37,982,228 RGD:9068941
G CP ceruloplasmin JBrowse link 23 43,969,297 44,033,226 RGD:9068941
G CRH corticotropin releasing hormone JBrowse link 29 15,831,944 15,840,560 RGD:9068941
G CRP C-reactive protein JBrowse link 38 22,396,787 22,398,180 RGD:9068941
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 JBrowse link 30 37,793,277 37,799,535 RGD:9068941
G CYP2D15 cytochrome P450 2D JBrowse link 10 23,255,259 23,259,380 RGD:9068941
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 JBrowse link 28 41,079,164 41,089,188 RGD:9068941
G DBH dopamine beta-hydroxylase JBrowse link 9 50,004,806 50,024,130 RGD:9068941
G DBN1 drebrin 1 JBrowse link 4 35,899,969 35,913,015 RGD:9068941
G DDC dopa decarboxylase JBrowse link 18 1,802,239 1,876,714 RGD:9068941
G DDIT4 DNA damage inducible transcript 4 JBrowse link 4 22,916,718 22,918,893 RGD:9068941
G DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit JBrowse link 2 78,268,540 78,275,789 RGD:9068941
G DLA-DRA MHC class II DR alpha chain JBrowse link 12 2,133,026 2,137,825 RGD:9068941
G DLG1 discs large MAGUK scaffold protein 1 JBrowse link 33 30,016,323 30,253,180 RGD:9068941
G DLG4 discs large MAGUK scaffold protein 4 JBrowse link 5 32,165,399 32,175,600 RGD:9068941
G DNAJC13 DnaJ heat shock protein family (Hsp40) member C13 JBrowse link 23 29,389,120 29,506,339 RGD:9068941
G DNAJC6 DnaJ heat shock protein family (Hsp40) member C6 JBrowse link 5 44,882,111 45,021,152 RGD:9068941
G DNM1L dynamin 1 like JBrowse link 27 16,161,855 16,211,983 RGD:9068941
G DRAXIN dorsal inhibitory axon guidance protein JBrowse link 2 84,515,881 84,525,797 RGD:9068941
G DRD1 dopamine receptor D1 JBrowse link 4 37,550,454 37,554,641 RGD:9068941
G DRD2 dopamine receptor D2 JBrowse link 5 19,732,842 19,795,241 RGD:9068941
G DRD3 dopamine receptor D3 JBrowse link 33 18,369,362 18,414,465 RGD:9068941
G DRD5 dopamine receptor D5 JBrowse link 3 69,621,187 69,623,522 RGD:9068941
G EDN1 endothelin 1 JBrowse link 35 11,808,892 11,815,383 RGD:9068941
G EGF epidermal growth factor JBrowse link 32 30,073,541 30,166,904 RGD:9068941
G EGFR epidermal growth factor receptor JBrowse link 18 5,983,669 6,044,092 RGD:9068941
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 JBrowse link 17 29,494,641 29,537,933 RGD:9068941
G EN1 engrailed homeobox 1 JBrowse link 19 31,124,325 31,129,538 RGD:9068941
G ENO2 enolase 2 JBrowse link 27 38,120,404 38,128,543 RGD:9068941
G EPHX1 epoxide hydrolase 1 JBrowse link 7 38,964,319 39,004,902 RGD:9068941
G EPHX2 epoxide hydrolase 2 JBrowse link 25 30,045,040 30,107,110 RGD:9068941
G EPO erythropoietin JBrowse link 6 8,994,211 8,995,954 RGD:9068941
G ERBB2 erb-b2 receptor tyrosine kinase 2 JBrowse link 9 22,760,373 22,785,367 RGD:9068941
G ESR2 estrogen receptor 2 JBrowse link 8 38,645,917 38,715,347 RGD:9068941
G FAS Fas cell surface death receptor JBrowse link 26 38,738,811 38,763,298 RGD:9068941
G FASLG Fas ligand JBrowse link 7 26,335,837 26,344,224 RGD:9068941
G FBP1 fructose-bisphosphatase 1 JBrowse link 1 72,099,886 72,125,266 RGD:9068941
G FBXO7 F-box protein 7 JBrowse link 10 30,928,059 30,948,858 RGD:9068941
G FCER2 Fc fragment of IgE receptor II JBrowse link 20 52,451,637 52,460,045 RGD:9068941
G FEZ1 fasciculation and elongation protein zeta 1 JBrowse link 5 9,001,927 9,044,330 RGD:9068941
G FGB fibrinogen beta chain JBrowse link 15 52,220,690 52,228,526 RGD:9068941
G FGF20 fibroblast growth factor 20 JBrowse link 16 40,330,793 40,339,925 RGD:9068941
G GAK cyclin G associated kinase JBrowse link 3 91,575,537 91,630,715 RGD:9068941
G GBA glucosylceramidase beta JBrowse link 7 42,317,704 42,322,285 RGD:9068941
G GDF5 growth differentiation factor 5 JBrowse link 24 24,395,699 24,400,302 RGD:9068941
G GDNF glial cell derived neurotrophic factor JBrowse link 4 70,966,694 70,991,860 RGD:9068941
G GFAP glial fibrillary acidic protein JBrowse link 9 18,569,868 18,579,463 RGD:9068941
G GJC2 gap junction protein gamma 2 JBrowse link 14 810,388 819,248 RGD:9068941
G GPR37 G protein-coupled receptor 37 JBrowse link 14 11,113,584 11,137,639 RGD:9068941
G GPX1 glutathione peroxidase 1 JBrowse link 20 39,889,165 39,890,253 RGD:9068941
G GRK2 G protein-coupled receptor kinase 2 JBrowse link 18 50,148,566 50,167,422 RGD:9068941
G GRK3 G protein-coupled receptor kinase 3 JBrowse link 26 19,385,059 19,512,528 RGD:9068941
G GRK5 G protein-coupled receptor kinase 5 JBrowse link 28 29,424,350 29,636,552 RGD:9068941
G GRK6 G protein-coupled receptor kinase 6 JBrowse link 4 35,927,470 35,943,218 RGD:9068941
G GRN granulin precursor JBrowse link 9 19,077,430 19,085,443 RGD:9068941
G GSK3B glycogen synthase kinase 3 beta JBrowse link 33 23,458,369 23,659,878 RGD:9068941
G GSTA4 glutathione S-transferase alpha 4 JBrowse link 12 20,426,724 20,443,200 RGD:9068941
G GSTO1 glutathione S-transferase omega 1 JBrowse link 28 16,569,421 16,579,239 RGD:9068941
G GSTO2 glutathione S-transferase omega 2 JBrowse link 28 16,580,250 16,604,977 RGD:9068941
G GSTP1 glutathione S-transferase pi 1 JBrowse link 18 49,905,161 49,908,182 RGD:9068941
G HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 JBrowse link 7 42,272,756 42,282,770 RGD:9068941
G HFE homeostatic iron regulator JBrowse link 35 24,031,479 24,038,922 RGD:9068941
G HGF hepatocyte growth factor JBrowse link 18 21,329,688 21,410,257 RGD:9068941
G HLA-DRB1 MHC class II DLA DRB1 beta chain JBrowse link 12 2,151,409 2,164,564 RGD:9068941
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 3 30,970,037 30,988,987 RGD:9068941
G HMOX1 heme oxygenase 1 JBrowse link 10 28,744,404 28,751,544 RGD:9068941
G HNMT histamine N-methyltransferase JBrowse link 19 40,656,266 40,702,498 RGD:9068941
G HSF1 heat shock transcription factor 1 JBrowse link 13 37,724,741 37,745,259 RGD:9068941
G HSPA4 heat shock protein family A (Hsp70) member 4 JBrowse link 11 21,290,603 21,363,701 RGD:9068941
G HSPA8 heat shock protein family A (Hsp70) member 8 JBrowse link 5 11,292,219 11,296,851 RGD:9068941
G HSPA9 heat shock protein family A (Hsp70) member 9 JBrowse link 11 26,122,917 26,142,458 RGD:9068941
G HSPD1 heat shock protein family D (Hsp60) member 1 JBrowse link 37 7,010,421 7,025,912 RGD:9068941
G HTR1A 5-hydroxytryptamine receptor 1A JBrowse link 2 50,005,277 50,006,548 RGD:9068941
G HTRA2 HtrA serine peptidase 2 JBrowse link 17 48,610,408 48,613,399 RGD:9068941
G HTT huntingtin JBrowse link 3 61,076,934 61,221,462 RGD:9068941
G IGF1R insulin like growth factor 1 receptor JBrowse link 3 41,795,337 42,096,255 RGD:9068941
G IGF2 insulin like growth factor 2 JBrowse link 18 46,294,036 46,311,982 RGD:9068941
G IGF2R insulin like growth factor 2 receptor JBrowse link 1 49,161,551 49,262,260 RGD:9068941
G IL1B interleukin 1 beta JBrowse link 17 37,019,329 37,033,388 RGD:9068941
G IL6 interleukin 6 JBrowse link 14 36,474,268 36,478,519 RGD:9068941
G INS insulin JBrowse link 18 46,324,047 46,324,933 RGD:9068941
G INSR insulin receptor JBrowse link 20 52,017,261 52,136,061 RGD:9068941
G KCNJ4 potassium inwardly rectifying channel subfamily J member 4 JBrowse link 10 26,321,274 26,348,978 RGD:9068941
G KCNN2 potassium calcium-activated channel subfamily N member 2 JBrowse link 11 4,279,362 4,423,080 RGD:9068941
G KLK6 kallikrein related peptidase 6 JBrowse link 1 105,902,147 105,907,585 RGD:9068941
G L1CAM L1 cell adhesion molecule JBrowse link X 121,708,695 121,722,819 RGD:9068941
G LEP leptin JBrowse link 14 8,115,396 8,130,946 RGD:9068941
G LOC100855763 transient receptor potential cation channel subfamily M member 2 JBrowse link 31 38,220,507 38,250,683 RGD:9068941
G LOC475937 transaldolase RGD:9068941
G LOC477699 alpha-2-macroglobulin JBrowse link 27 36,654,328 36,695,775 RGD:9068941
G LOC609402 hemoglobin subunit beta-like JBrowse link 21 28,187,535 28,188,991 RGD:9068941
G LOXL3 lysyl oxidase like 3 JBrowse link 17 48,590,996 48,610,264 RGD:9068941
G LRRK2 leucine rich repeat kinase 2 JBrowse link 27 13,282,824 13,420,917 RGD:9068941
G MAG myelin associated glycoprotein JBrowse link 1 117,288,306 117,301,975 RGD:9068941
G MAOA monoamine oxidase A JBrowse link X 37,678,933 37,744,757 RGD:9068941
G MAOB monoamine oxidase B JBrowse link X 37,765,810 37,883,955 RGD:9068941
G MAP2 microtubule associated protein 2 JBrowse link 37 17,316,899 17,611,360 RGD:9068941
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 JBrowse link 1 29,107,813 29,306,437 RGD:9068941
G MAPT microtubule associated protein tau JBrowse link 9 9,572,174 9,674,082 RGD:9068941
G MIR1-2 microRNA mir-1-2 JBrowse link 7 66,214,380 66,214,438 RGD:9068941
G MIR132 microRNA mir-132 JBrowse link 9 46,153,531 46,153,590 RGD:9068941
G MIR181C microRNA mir-181c JBrowse link 20 48,593,343 48,593,403 RGD:9068941
G MIR19B-1 microRNA mir-19b-1 JBrowse link 22 42,478,598 42,478,656 RGD:9068941
G MIR22 microRNA mir-22 JBrowse link 9 45,852,534 45,852,593 RGD:9068941
G MIR29B-1 microRNA mir-29b-1 JBrowse link 14 6,184,457 6,184,521 RGD:9068941
G MIR301A microRNA mir-301a JBrowse link 9 33,724,572 33,724,655 RGD:9068941
G MIR34B microRNA mir-34b JBrowse link 5 21,558,685 21,558,768 RGD:9068941
G MIR34C microRNA mir-34c JBrowse link 5 21,558,106 21,558,160 RGD:9068941
G MTA1 metastasis associated 1 JBrowse link 8 72,752,894 72,772,236 RGD:9068941
G MTHFR methylenetetrahydrofolate reductase JBrowse link 2 84,445,526 84,457,435 RGD:9068941
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase JBrowse link 34 6,068,572 6,119,580 RGD:9068941
G NANOG Nanog homeobox JBrowse link 27 37,262,558 37,266,449 RGD:9068941
G NCAPG2 non-SMC condensin II complex subunit G2 JBrowse link 16 20,649,088 20,712,208 RGD:9068941
G ND1 NADH dehydrogenase subunit 1 JBrowse link MT 2,747 3,702 RGD:9068941
G ND2 NADH dehydrogenase subunit 2 JBrowse link MT 3,914 4,955 RGD:9068941
G ND3 NADH dehydrogenase subunit 3 JBrowse link MT 9,496 9,841 RGD:9068941
G ND4 NADH dehydrogenase subunit 4 JBrowse link MT 10,201 11,578 RGD:9068941
G NDUFA13 NADH:ubiquinone oxidoreductase subunit A13 JBrowse link 20 43,721,568 43,730,607 RGD:9068941
G NDUFB8 NADH:ubiquinone oxidoreductase subunit B8 JBrowse link 28 13,249,067 13,253,670 RGD:9068941
G NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 JBrowse link 37 14,680,908 14,713,838 RGD:9068941
G NDUFS4 NADH:ubiquinone oxidoreductase subunit S4 JBrowse link 4 61,613,580 61,727,219 RGD:9068941
G NDUFV2 NADH:ubiquinone oxidoreductase core subunit V2 JBrowse link 7 75,150,293 75,184,084 RGD:9068941
G NECTIN2 nectin cell adhesion molecule 2 JBrowse link 1 110,543,140 110,569,168 RGD:9068941
G NEDD8 NEDD8 ubiquitin like modifier JBrowse link 8 4,202,621 4,213,090 RGD:9068941
G NGF nerve growth factor JBrowse link 17 52,900,647 52,901,607 RGD:9068941
G NGFR nerve growth factor receptor JBrowse link 9 25,598,468 25,621,021 RGD:9068941
G NOS1 nitric oxide synthase 1 JBrowse link 26 13,787,341 13,895,176 RGD:9068941
G NOS2 nitric oxide synthase 2 JBrowse link 9 42,171,821 42,210,217 RGD:9068941
G NQO1 NAD(P)H quinone dehydrogenase 1 JBrowse link 5 79,979,593 79,990,875 RGD:9068941
G NQO2 N-ribosyldihydronicotinamide:quinone reductase 2 JBrowse link 35 3,294,776 3,315,438 RGD:9068941
G NR4A2 nuclear receptor subfamily 4 group A member 2 JBrowse link 36 2,546,237 2,554,559 RGD:9068941
G NTSR1 neurotensin receptor 1 JBrowse link 24 46,576,690 46,615,192 RGD:9068941
G OGG1 8-oxoguanine DNA glycosylase JBrowse link 20 8,486,150 8,491,448 RGD:9068941
G OPTN optineurin JBrowse link 2 23,356,471 23,390,569 RGD:9068941
G ORC6 origin recognition complex subunit 6 JBrowse link 15 8,421,297 8,427,972 RGD:9068941
G PARK7 Parkinsonism associated deglycase JBrowse link 5 61,576,219 61,592,325 RGD:9068941
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 7 38,503,072 38,542,556 RGD:9068941
G PENK proenkephalin JBrowse link 29 7,757,543 7,763,137 RGD:9068941
G PHACTR2 phosphatase and actin regulator 2 JBrowse link 1 35,158,678 35,348,875 RGD:9068941
G PINK1 PTEN induced kinase 1 JBrowse link 2 78,276,091 78,293,761 RGD:9068941
G PITX3 paired like homeodomain 3 JBrowse link 28 14,760,741 14,775,584 RGD:9068941
G PLA2G6 phospholipase A2 group VI JBrowse link 10 26,499,033 26,559,533 RGD:9068941
G POLG DNA polymerase gamma, catalytic subunit JBrowse link 3 52,357,062 52,373,768 RGD:9068941
G PPARGC1A PPARG coactivator 1 alpha JBrowse link 3 85,645,942 86,284,570 RGD:9068941
G PPP1R9B protein phosphatase 1 regulatory subunit 9B JBrowse link 9 26,135,982 26,152,303 RGD:9068941
G PPP2CA protein phosphatase 2 catalytic subunit alpha JBrowse link 11 22,388,327 22,410,052 RGD:9068941
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 1 49,886,887 51,201,930 RGD:9068941
G PTN pleiotrophin JBrowse link 16 11,283,078 11,382,820 RGD:9068941
G RPL14 ribosomal protein L14 JBrowse link 23 9,907,479 9,911,114 RGD:9068941
G RPL23A ribosomal protein L23a JBrowse link 9 42,915,106 42,918,795 RGD:9068941
G RPL6 ribosomal protein L6 JBrowse link 26 9,970,416 9,975,897 RGD:9068941
G RPS8 ribosomal protein S8 JBrowse link 15 15,542,569 15,545,285 RGD:9068941
G RRN3 RRN3 homolog, RNA polymerase I transcription factor JBrowse link 6 28,478,770 28,507,722 RGD:9068941
G S100B S100 calcium binding protein B JBrowse link 31 39,783,990 39,788,289 RGD:9068941
G SDHA succinate dehydrogenase complex flavoprotein subunit A JBrowse link 34 11,935,684 11,965,094 RGD:9068941
G SEPTIN14 septin 14 JBrowse link 18 25,103,092 25,201,880 RGD:9068941
G SEPTIN4 septin 4 JBrowse link 9 33,138,167 33,162,212 RGD:9068941
G SLC11A2 solute carrier family 11 member 2 JBrowse link 27 3,788,785 3,823,852 RGD:9068941
G SLC18A2 solute carrier family 18 member A2 JBrowse link 28 27,731,709 27,809,341 RGD:9068941
G SLC30A10 solute carrier family 30 member 10 JBrowse link 38 14,705,517 14,746,835 RGD:9068941
G SLC6A3 solute carrier family 6 member 3 JBrowse link 34 11,209,118 11,245,456 RGD:9068941
G SNCA synuclein alpha JBrowse link 32 12,915,871 13,079,338 RGD:9068941
G SNCAIP synuclein alpha interacting protein JBrowse link 11 12,226,940 12,375,725 RGD:9068941
G SNCB synuclein beta JBrowse link 4 36,710,236 36,719,455 RGD:9068941
G SNCG synuclein gamma JBrowse link 4 34,604,867 34,608,851 RGD:9068941
G SOD1 superoxide dismutase 1 JBrowse link 31 26,540,291 26,544,212 RGD:9068941
G SOD2 superoxide dismutase 2 JBrowse link 1 48,943,472 48,955,158 RGD:9068941
G SPR sepiapterin reductase JBrowse link 17 49,950,192 49,957,455 RGD:9068941
G SRRM2 serine/arginine repetitive matrix 2 JBrowse link 6 38,291,847 38,310,624 RGD:9068941
G SYNJ1 synaptojanin 1 JBrowse link 31 27,308,169 27,399,226 RGD:9068941
G TARDBP TAR DNA binding protein JBrowse link 2 84,987,752 84,998,136 RGD:9068941
G TCL1B T cell leukemia/lymphoma 1B JBrowse link 8 64,497,560 64,500,412 RGD:9068941
G TCN2 transcobalamin 2 JBrowse link 26 23,693,664 23,710,342 RGD:9068941
G TDGF1 teratocarcinoma-derived growth factor 1 JBrowse link 20 42,137,939 42,140,590 RGD:9068941
G TFAM transcription factor A, mitochondrial JBrowse link 4 10,585,320 10,600,664 RGD:9068941
G TH tyrosine hydroxylase JBrowse link 18 46,327,136 46,334,973 RGD:9068941
G TMEM230 transmembrane protein 230 JBrowse link 24 16,486,514 16,496,180 RGD:9068941
G TNF tumor necrosis factor JBrowse link 12 1,074,561 1,076,425 RGD:9068941
G TNFRSF1B TNF receptor superfamily member 1B JBrowse link 2 84,140,179 84,151,219 RGD:9068941
G TNK2 tyrosine kinase non receptor 2 JBrowse link 33 29,153,636 29,177,568 RGD:9068941
G TNR tenascin R JBrowse link 7 23,721,227 24,125,183 RGD:9068941
G TWNK twinkle mtDNA helicase JBrowse link 28 13,672,772 13,680,732 RGD:9068941
G UCHL1 ubiquitin C-terminal hydrolase L1 JBrowse link 3 71,396,694 71,430,395 RGD:9068941
G VDAC1 voltage dependent anion channel 1 JBrowse link 11 22,197,814 22,212,924 RGD:9068941
G VDR vitamin D receptor JBrowse link 27 6,852,915 6,909,466 RGD:9068941
G VIP vasoactive intestinal peptide JBrowse link 1 42,941,655 42,950,160 RGD:9068941
G VPS13C vacuolar protein sorting 13 homolog C JBrowse link 30 26,600,181 26,776,347 RGD:9068941
G VPS35 VPS35 retromer complex component JBrowse link 15 8,428,073 8,454,601 RGD:9068941
amyotrophic lateral sclerosis-parkinsonism/dementia complex 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TRPM7 transient receptor potential cation channel subfamily M member 7 JBrowse link 30 16,465,546 16,579,874 RGD:7240710
RGD:9068941
Early Onset Parkinsonism with Mental Retardation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CLIC2 chloride intracellular channel 2 JBrowse link X 123,268,867 123,291,467 RGD:9068941
G RAB39B RAB39B, member RAS oncogene family JBrowse link X 123,245,227 123,251,283 RGD:7240710
RGD:9068941
Kufor-Rakeb syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP13A2 ATPase cation transporting 13A2 JBrowse link 2 81,196,355 81,215,736 RGD:7240710
RGD:9068941
late onset Parkinson's disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATXN2 ataxin 2 JBrowse link 26 9,073,667 9,188,429 RGD:7240710
RGD:9068941
G DBH dopamine beta-hydroxylase JBrowse link 9 50,004,806 50,024,130 RGD:9068941
G DLA-DRA MHC class II DR alpha chain JBrowse link 12 2,133,026 2,137,825 RGD:9068941
G DNAJC13 DnaJ heat shock protein family (Hsp40) member C13 JBrowse link 23 29,389,120 29,506,339 RGD:9068941
G EIF4G1 eukaryotic translation initiation factor 4 gamma 1 JBrowse link 34 17,194,588 17,214,498 RGD:7240710
RGD:9068941
G FGF20 fibroblast growth factor 20 JBrowse link 16 40,330,793 40,339,925 RGD:9068941
G GBA glucosylceramidase beta JBrowse link 7 42,317,704 42,322,285 RGD:7240710
RGD:9068941
G GSTP1 glutathione S-transferase pi 1 JBrowse link 18 49,905,161 49,908,182 RGD:9068941
G LRRK2 leucine rich repeat kinase 2 JBrowse link 27 13,282,824 13,420,917 RGD:9068941
G MAPT microtubule associated protein tau JBrowse link 9 9,572,174 9,674,082 RGD:7240710
RGD:9068941
G MC1R melanocortin 1 receptor JBrowse link 5 63,694,296 63,695,249 RGD:9068941
G ND1 NADH dehydrogenase subunit 1 JBrowse link MT 2,747 3,702 RGD:9068941
G NR4A2 nuclear receptor subfamily 4 group A member 2 JBrowse link 36 2,546,237 2,554,559 RGD:9068941
G PARK7 Parkinsonism associated deglycase JBrowse link 5 61,576,219 61,592,325 RGD:9068941
G PINK1 PTEN induced kinase 1 JBrowse link 2 78,276,091 78,293,761 RGD:9068941
G PODXL podocalyxin like JBrowse link 14 5,614,006 5,625,360 RGD:9068941
G SNCAIP synuclein alpha interacting protein JBrowse link 11 12,226,940 12,375,725 RGD:9068941
G TBP TATA-box binding protein JBrowse link 12 72,458,959 72,479,271 RGD:7240710
RGD:9068941
G UCHL1 ubiquitin C-terminal hydrolase L1 JBrowse link 3 71,396,694 71,430,395 RGD:7240710
RGD:9068941
G VPS35 VPS35 retromer complex component JBrowse link 15 8,428,073 8,454,601 RGD:9068941
Parkinson's disease 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SNCA synuclein alpha JBrowse link 32 12,915,871 13,079,338 RGD:7240710
RGD:9068941
Parkinson's Disease 11 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GIGYF2 GRB10 interacting GYF protein 2 JBrowse link 25 44,317,540 44,453,761 RGD:7240710
RGD:9068941
Parkinson's Disease 13 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HTRA2 HtrA serine peptidase 2 JBrowse link 17 48,610,408 48,613,399 RGD:7240710
RGD:9068941
G LOXL3 lysyl oxidase like 3 JBrowse link 17 48,590,996 48,610,264 RGD:9068941
Parkinson's disease 14 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PLA2G6 phospholipase A2 group VI JBrowse link 10 26,499,033 26,559,533 RGD:7240710
RGD:9068941
Parkinson's disease 15 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FBXO7 F-box protein 7 JBrowse link 10 30,928,059 30,948,858 RGD:7240710
RGD:9068941
Parkinson's disease 17 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G VPS35 VPS35 retromer complex component JBrowse link 15 8,428,073 8,454,601 RGD:7240710
RGD:9068941
Parkinson's disease 19A term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DNAJC6 DnaJ heat shock protein family (Hsp40) member C6 JBrowse link 5 44,882,111 45,021,152 RGD:7240710
RGD:9068941
Parkinson's disease 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PACRG parkin coregulated JBrowse link 1 51,202,146 51,717,076 RGD:9068941
G PODXL podocalyxin like JBrowse link 14 5,614,006 5,625,360 RGD:9068941
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 1 49,886,887 51,201,930 RGD:7240710
RGD:9068941
Parkinson's disease 20 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CFAP298 cilia and flagella associated protein 298 JBrowse link 31 27,296,841 27,305,941 RGD:9068941
G SYNJ1 synaptojanin 1 JBrowse link 31 27,308,169 27,399,226 RGD:7240710
RGD:9068941
Parkinson's disease 21 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DNAJC13 DnaJ heat shock protein family (Hsp40) member C13 JBrowse link 23 29,389,120 29,506,339 RGD:7240710
RGD:9068941
Parkinson's disease 22 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 JBrowse link 6 581,276 585,367 RGD:7240710
RGD:9068941
Parkinson's disease 23 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G VPS13C vacuolar protein sorting 13 homolog C JBrowse link 30 26,600,181 26,776,347 RGD:7240710
RGD:9068941
Parkinson's disease 4 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SNCA synuclein alpha JBrowse link 32 12,915,871 13,079,338 RGD:7240710
RGD:9068941
Parkinson's Disease 5 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G UCHL1 ubiquitin C-terminal hydrolase L1 JBrowse link 3 71,396,694 71,430,395 RGD:9068941
Parkinson's disease 6 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MTFP1 mitochondrial fission process 1 JBrowse link 26 23,565,438 23,568,919 RGD:9068941
G ND5 NADH dehydrogenase subunit 5 JBrowse link MT 11,778 13,598 RGD:9068941
G ND6 NADH dehydrogenase subunit 6 JBrowse link MT 13,582 14,109 RGD:9068941
G PARK7 Parkinsonism associated deglycase JBrowse link 5 61,576,219 61,592,325 RGD:9068941
G PINK1 PTEN induced kinase 1 JBrowse link 2 78,276,091 78,293,761 RGD:7240710
RGD:9068941
Parkinson's disease 7 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARK7 Parkinsonism associated deglycase JBrowse link 5 61,576,219 61,592,325 RGD:7240710
RGD:9068941
Parkinson's disease 8 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LRRK2 leucine rich repeat kinase 2 JBrowse link 27 13,282,824 13,420,917 RGD:7240710
RGD:9068941
Parkinson's Disease, Mitochondrial term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FMC1 formation of mitochondrial complex V assembly factor 1 homolog JBrowse link 16 9,413,358 9,418,791 RGD:9068941
G NDUFV2 NADH:ubiquinone oxidoreductase core subunit V2 JBrowse link 7 75,150,293 75,184,084 RGD:9068941
Parkinson's Disease, X-Linked Dominant term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RAB39B RAB39B, member RAS oncogene family JBrowse link X 123,245,227 123,251,283 RGD:9068941
Parkinsonism with Spasticity, X-Linked term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP6AP2 ATPase H+ transporting accessory protein 2 JBrowse link X 35,050,588 35,073,633 RGD:7240710
RGD:9068941
G G6PD glucose-6-phosphate dehydrogenase JBrowse link X 122,217,317 122,231,862 RGD:9068941
Parkinsonism-Dystonia, Infantile term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SLC6A3 solute carrier family 6 member 3 JBrowse link 34 11,209,118 11,245,456 RGD:9068941
Parkinsonism-Dystonia, Infantile, 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SLC6A3 solute carrier family 6 member 3 JBrowse link 34 11,209,118 11,245,456 RGD:7240710
RGD:9068941
Parkinsonism-Dystonia, Infantile, 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SLC18A2 solute carrier family 18 member A2 JBrowse link 28 27,731,709 27,809,341 RGD:7240710
RGD:9068941
Progressive Supranuclear Palsy Atypical term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MAPT microtubule associated protein tau JBrowse link 9 9,572,174 9,674,082 RGD:7240710
RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 12112
    disease of anatomical entity 11766
      nervous system disease 9455
        neurodegenerative disease 2775
          synucleinopathy 261
            Parkinson's disease 238
              Parkinson's Disease 10 0
              Parkinson's Disease 11 1
              Parkinson's Disease 12 0
              Parkinson's Disease 13 2
              Parkinson's Disease 16 0
              Parkinson's Disease 5 1
              Parkinson's Disease, Mitochondrial 2
              Parkinson's Disease, X-Linked Dominant 1
              Parkinsonism with Spasticity, X-Linked 2
              Parkinsonism-Dystonia, Infantile + 2
              Progressive Supranuclear Palsy Atypical 1
              amyotrophic lateral sclerosis-parkinsonism/dementia complex 1 1
              early-onset Parkinson's disease + 16
              late onset Parkinson's disease + 23
Path 2
Term Annotations click to browse term
  disease 12112
    disease of anatomical entity 11766
      nervous system disease 9455
        central nervous system disease 7852
          brain disease 7248
            basal ganglia disease 515
              Parkinsonian Disorders 311
                Parkinson's disease 238
                  Parkinson's Disease 10 0
                  Parkinson's Disease 11 1
                  Parkinson's Disease 12 0
                  Parkinson's Disease 13 2
                  Parkinson's Disease 16 0
                  Parkinson's Disease 5 1
                  Parkinson's Disease, Mitochondrial 2
                  Parkinson's Disease, X-Linked Dominant 1
                  Parkinsonism with Spasticity, X-Linked 2
                  Parkinsonism-Dystonia, Infantile + 2
                  Progressive Supranuclear Palsy Atypical 1
                  amyotrophic lateral sclerosis-parkinsonism/dementia complex 1 1
                  early-onset Parkinson's disease + 16
                  late onset Parkinson's disease + 23
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.