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ONTOLOGY REPORT - ANNOTATIONS


Term:Parkinson's disease
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Accession:DOID:14330 term browser browse the term
Definition:A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
Synonyms:exact_synonym: Idiopathic Parkinson's Disease;   Lewy Body Parkinson Disease;   Lewy Body Parkinson's Disease;   PARKINSON DISEASE, DOMINANT/RECESSIVE;   PARKINSON'S DISEASE, DOMINANT;   PARKINSON'S DISEASE, DOMINANT/RECESSIVE;   PARKINSON'S DISEASE, RECESSIVE;   PARKINSON'S DISEASE, RESISTANCE TO;   Paralysis Agitans;   Parkinson Disease;   idiopathic Parkinson disease;   primary parkinsonism
 narrow_synonym: PARKINSON DISEASE, DOMINANT;   PARKINSON DISEASE, RECESSIVE;   PARKINSONISM/MELAS OVERLAP SYNDROME;   familial Parkinson's disease
 related_synonym: DOPAMINE BETA-HYDROXYLASE ACTIVITY, PLASMA;   PARKINSON DISEASE, AGE AT ONSET, SUSCEPTIBILITY TO;   PARKINSON DISEASE, RESISTANCE TO;   Parkinson Disease, Susceptibility To;   Parkinson's disease, susceptibility to
 primary_id: MESH:D010300
 alt_id: RDO:0002963
 xref: GARD:10251;   ICD9CM:332;   ICD9CM:332.0;   NCI:C26845;   OMIM:PS168600;   ORDO:2828
For additional species annotation, visit the Alliance of Genome Resources.


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Parkinson's disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G A2M alpha-2-macroglobulin JBrowse link 5 62,406,928 62,483,690 RGD:9068941
G ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 JBrowse link 9 93,049,955 93,146,469 RGD:9068941
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 1 270,761,641 270,906,708 RGD:9068941
G ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 JBrowse link 12 15,394,487 15,414,609 RGD:9068941
G ACHE acetylcholinesterase (Cartwright blood group) JBrowse link 3 8,732,451 8,738,274 RGD:9068941
G ADARB2 adenosine deaminase RNA specific B2 (inactive) JBrowse link 10 68,013,531 68,468,583 RGD:9068941
G ADCY5 adenylate cyclase 5 JBrowse link 13 136,965,746 137,133,795 RGD:9068941
G AFDN afadin, adherens junction formation factor JBrowse link 1 1,569,652 1,698,475 RGD:9068941
G AGTR1 angiotensin II receptor type 1 JBrowse link 13 88,934,873 88,980,317 RGD:9068941
G AIF1 allograft inflammatory factor 1 JBrowse link 7 23,711,752 23,731,191 RGD:9068941
G AKT1 AKT serine/threonine kinase 1 RGD:9068941
G ANG angiogenin JBrowse link 7 78,249,479 78,262,846 RGD:9068941
G ANXA5 annexin A5 JBrowse link 8 102,387,833 102,420,868 RGD:9068941
G APAF1 apoptotic peptidase activating factor 1 JBrowse link 5 85,166,616 85,258,751 RGD:9068941
G APOA1 apolipoprotein A1 JBrowse link 9 44,216,481 44,218,360 RGD:9068941
G APOE apolipoprotein E JBrowse link 6 51,373,113 51,375,333 RGD:9068941
G ARPC3 actin related protein 2/3 complex subunit 3 JBrowse link 14 31,814,382 31,823,452 RGD:9068941
G ATG7 autophagy related 7 JBrowse link 13 67,301,756 67,699,141 RGD:9068941
G ATM ATM serine/threonine kinase JBrowse link 9 36,620,656 36,759,555 RGD:9068941
G ATP13A2 ATPase cation transporting 13A2 JBrowse link 6 75,618,317 75,638,591 RGD:9068941
G ATP6 ATP synthase F0 subunit 6 JBrowse link MT 9,120 9,800 RGD:9068941
G AUP1 AUP1 lipid droplet regulating VLDL assembly factor JBrowse link 3 68,520,048 68,523,076 RGD:9068941
G B2M beta-2-microglobulin JBrowse link 1 126,837,721 126,844,043 RGD:9068941
G BAG5 BAG cochaperone 5 RGD:9068941
G BDNF brain derived neurotrophic factor JBrowse link 2 32,623,668 32,679,293 RGD:9068941
G BGLAP bone gamma-carboxyglutamate protein JBrowse link 4 93,807,703 93,808,806 RGD:9068941
G BST1 bone marrow stromal cell antigen 1 JBrowse link 8 11,011,131 11,043,622 RGD:9068941
G CASP3 caspase 3 JBrowse link 15 45,744,320 45,753,252 RGD:9068941
G CASP9 caspase 9 JBrowse link 6 74,707,597 74,730,033 RGD:9068941
G CAST calpastatin JBrowse link 2 103,255,738 103,378,623 RGD:9068941
G CCK cholecystokinin JBrowse link 13 25,940,674 25,945,879 RGD:9068941
G CCN2 cellular communication network factor 2 JBrowse link 1 31,674,398 31,677,697 RGD:9068941
G CNTNAP2 contactin associated protein 2 JBrowse link 9 109,740,510 111,781,144 RGD:9068941
G COL19A1 collagen type XIX alpha 1 chain JBrowse link 1 50,044,394 50,402,256 RGD:9068941
G COX10 COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) JBrowse link 12 58,011,831 58,110,575 RGD:9068941
G CP ceruloplasmin JBrowse link 13 89,396,713 89,463,540 RGD:9068941
G CRH corticotropin releasing hormone JBrowse link 4 68,481,696 68,486,122 RGD:9068941
G CRP C-reactive protein, pentraxin-related JBrowse link 4 90,793,361 90,801,020 RGD:9068941
G CYP1A1 cytochrome P450 1A1 JBrowse link 7 58,802,887 58,809,155 RGD:9068941
G CYP2D25 vitamin D3 25-Hydroxylase JBrowse link 5 6,539,021 6,543,643 RGD:9068941
G CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 JBrowse link 14 141,690,737 141,703,078 RGD:9068941
G DBH dopamine beta-hydroxylase JBrowse link 1 273,204,407 273,225,562 RGD:9068941
G DBN1 drebrin 1 JBrowse link 2 80,480,603 80,495,797 RGD:9068941
G DDC dopa decarboxylase JBrowse link 9 136,496,364 136,571,220 RGD:9068941
G DDIT4 DNA damage inducible transcript 4 JBrowse link 14 75,117,708 75,119,907 RGD:9068941
G DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit JBrowse link 6 78,885,268 78,895,720 RGD:9068941
G DLG1 discs large MAGUK scaffold protein 1 JBrowse link 13 132,819,931 133,084,880 RGD:9068941
G DLG4 discs large MAGUK scaffold protein 4 JBrowse link 12 52,550,138 52,574,021 RGD:9068941
G DNAJC13 DnaJ heat shock protein family (Hsp40) member C13 JBrowse link 13 73,573,887 73,707,951 RGD:9068941
G DNAJC6 DnaJ heat shock protein family (Hsp40) member C6 JBrowse link 6 146,990,115 147,161,010 RGD:9068941
G DNM1L dynamin 1 like JBrowse link 5 41,571,054 41,636,058 RGD:9068941
G DRAXIN dorsal inhibitory axon guidance protein JBrowse link 6 71,786,806 71,814,946 RGD:9068941
G DRD1 dopamine receptor D1 JBrowse link 16 49,189,555 49,193,722 RGD:9068941
G DRD2 dopamine receptor D2 JBrowse link 9 41,068,618 41,135,262 RGD:9068941
G DRD3 dopamine receptor D3 JBrowse link 13 145,769,294 145,817,997 RGD:9068941
G DRD5 dopamine receptor D5 JBrowse link 8 6,180,221 6,182,575 RGD:9068941
G EDN1 endothelin 1 JBrowse link 7 8,752,018 8,758,354 RGD:9068941
G EGF epidermal growth factor JBrowse link 8 112,235,607 112,330,062 RGD:9068941
G EGFR epidermal growth factor receptor JBrowse link 9 139,302,410 139,474,632 RGD:9068941
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 JBrowse link 3 103,041,029 103,096,741 RGD:9068941
G EN1 engrailed homeobox 1 JBrowse link 15 24,402,605 24,408,377 RGD:9068941
G ENO2 enolase 2 JBrowse link 5 63,799,927 63,809,067 RGD:9068941
G EPHX1 epoxide hydrolase 1 JBrowse link 10 13,757,489 13,773,071 RGD:9068941
G EPHX2 epoxide hydrolase 2 JBrowse link 14 11,217,125 11,293,018 RGD:9068941
G EPO erythropoietin JBrowse link 3 8,620,508 8,622,936 RGD:9068941
G ERBB2 erb-b2 receptor tyrosine kinase 2 JBrowse link 12 22,591,621 22,621,384 RGD:9068941
G ESR2 estrogen receptor 2 JBrowse link 1 193,823,666 193,907,330 RGD:9068941
G FAS Fas cell surface death receptor JBrowse link 14 100,927,305 100,954,781 RGD:9068941
G FASLG Fas ligand (TNF superfamily, member 6) JBrowse link 9 115,068,314 115,075,147 RGD:9068941
G FBP1 fructose-bisphosphatase 1 JBrowse link 10 27,588,609 27,622,225 RGD:9068941
G FBXO7 F-box protein 7 JBrowse link 5 12,505,646 12,526,206 RGD:9068941
G FCER2 Fc fragment of IgE receptor II JBrowse link 2 71,454,046 71,468,149 RGD:9068941
G FEZ1 fasciculation and elongation protein zeta 1 JBrowse link 9 52,621,175 52,672,660 RGD:9068941
G FGB fibrinogen beta chain JBrowse link 8 74,598,170 74,607,409 RGD:9068941
G FGF20 fibroblast growth factor 20 JBrowse link 17 4,691,448 4,700,367 RGD:9068941
G GAK cyclin G associated kinase JBrowse link 8 240,818 296,989 RGD:9068941
G GBA glucosylceramidase beta JBrowse link 4 94,583,905 94,606,689 RGD:9068941
G GDF5 growth differentiation factor 5 JBrowse link 17 38,792,854 38,796,806 RGD:9068941
G GDNF glial cell derived neurotrophic factor JBrowse link 16 22,936,602 22,965,929 RGD:9068941
G GFAP glial fibrillary acidic protein JBrowse link 12 18,456,268 18,466,594 RGD:9068941
G GJC2 gap junction protein gamma 2 JBrowse link 2 51,257,623 51,267,969 RGD:9068941
G GPR37 G protein-coupled receptor 37 JBrowse link 18 23,019,752 23,036,483 RGD:9068941
G GPX1 glutathione peroxidase 1 JBrowse link 13 31,916,269 31,917,337 RGD:9068941
G GRK2 G protein-coupled receptor kinase 2 JBrowse link 2 5,209,435 5,227,543 RGD:9068941
G GRK3 G protein-coupled receptor kinase 3 JBrowse link 14 43,305,255 43,445,626 RGD:9068941
G GRK5 G protein-coupled receptor kinase 5 JBrowse link 14 129,113,933 129,351,135 RGD:9068941
G GRK6 G protein-coupled receptor kinase 6 JBrowse link 2 80,496,105 80,527,208 RGD:9068941
G GRN granulin precursor JBrowse link 12 18,893,772 18,900,444 RGD:9068941
G GSK3B glycogen synthase kinase 3 beta JBrowse link 13 140,136,109 140,370,197 RGD:9068941
G GSTA4 glutathione S-transferase alpha 4 JBrowse link 7 46,635,903 46,656,491 RGD:9068941
G GSTO1 glutathione S-transferase omega 1 JBrowse link 14 115,206,434 115,216,624 RGD:9068941
G HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 JBrowse link 4 94,545,919 94,560,105 RGD:9068941
G HFE homeostatic iron regulator JBrowse link 7 20,758,604 20,767,004 RGD:9068941
G HGF hepatocyte growth factor JBrowse link 9 98,437,771 98,513,573 RGD:9068941
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 84,380,245 84,401,117 RGD:9068941
G HMOX1 heme oxygenase 1 RGD:9068941
G HNMT histamine N-methyltransferase JBrowse link 15 13,733,412 13,768,106 RGD:9068941
G HSF1 heat shock transcription factor 1 JBrowse link 4 463,531 486,483 RGD:9068941
G HSPA4 heat shock protein family A (Hsp70) member 4 JBrowse link 2 135,345,724 135,391,112 RGD:9068941
G HSPA8 heat shock protein family A (Hsp70) member 8 JBrowse link 9 49,982,278 49,986,760 RGD:9068941
G HSPA9 heat shock protein family A (Hsp70) member 9 JBrowse link 2 140,515,239 140,532,164 RGD:9068941
G HSPD1 heat shock protein family D (Hsp60) member 1 JBrowse link 15 101,360,355 101,373,498 RGD:9068941
G HTR1A 5-hydroxytryptamine receptor 1A JBrowse link 16 42,479,812 42,484,365 RGD:9068941
G HTRA2 HtrA serine peptidase 2 JBrowse link 3 68,516,666 68,520,025 RGD:9068941
G HTT huntingtin JBrowse link 8 1,809,768 1,934,002 RGD:9068941
G IGF1R insulin like growth factor 1 receptor JBrowse link 1 137,383,623 137,691,038 RGD:9068941
G IGF2 insulin like growth factor 2 JBrowse link 2 1,469,183 1,496,417 RGD:9068941
G IGF2R insulin like growth factor 2 receptor JBrowse link 1 7,369,485 7,472,480 RGD:9068941
G IL6 interleukin 6 JBrowse link 9 91,506,421 91,510,830 RGD:9068941
G INS insulin JBrowse link 2 1,496,842 1,498,052 RGD:9068941
G INSR insulin receptor JBrowse link 2 71,797,209 71,939,923 RGD:9068941
G KCNJ4 potassium inwardly rectifying channel subfamily J member 4 JBrowse link 5 9,526,399 9,549,290 RGD:9068941
G KCNN2 potassium calcium-activated channel subfamily N member 2 JBrowse link 2 118,439,328 118,882,299 RGD:9068941
G KLK6 kallikrein related peptidase 6 JBrowse link 6 55,629,983 55,639,215 RGD:9068941
G L1CAM L1 cell adhesion molecule JBrowse link X 124,595,649 124,618,292 RGD:9068941
G LEP leptin JBrowse link 18 20,106,867 20,124,071 RGD:9068941
G LOC100152209 glutathione S-transferase omega-2 JBrowse link 14 115,218,179 115,242,377 RGD:9068941
G LOC100739087 60S ribosomal protein L14-like JBrowse link 1 56,689,050 56,689,768 RGD:9068941
G LOC100739163 glutathione S-transferase P-like JBrowse link 2 4,978,761 4,982,233 RGD:9068941
G LOC110258578 interleukin-1 beta-like RGD:9068941
G LOXL3 lysyl oxidase like 3 JBrowse link 3 68,498,114 68,516,829 RGD:9068941
G LRRK2 leucine rich repeat kinase 2 JBrowse link 5 71,800,337 71,945,828 RGD:9068941
G MAG myelin associated glycoprotein JBrowse link 6 44,794,197 44,809,933 RGD:9068941
G MAOA monoamine oxidase A JBrowse link X 38,930,452 39,006,220 RGD:9068941
G MAOB monoamine oxidase B JBrowse link X 39,025,973 39,144,389 RGD:9068941
G MAP2 microtubule associated protein 2 JBrowse link 15 112,156,578 112,462,932 RGD:9068941
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 JBrowse link 1 27,380,143 27,600,500 RGD:9068941
G MAPT microtubule associated protein tau JBrowse link 12 17,098,259 17,211,483 RGD:9068941
G MIR181C microRNA mir-181c JBrowse link 2 65,279,950 65,280,036 RGD:9068941
G MIR19B-1 microRNA mir-19b-1 JBrowse link 11 60,735,238 60,735,317 RGD:9068941
G MIR29B-1 microRNA mir-29b-1 JBrowse link 18 18,039,629 18,039,709 RGD:9068941
G MIR34C-1 microRNA mir-34c-1 JBrowse link 9 39,280,278 39,280,357 RGD:9068941
G MTA1 metastasis associated 1 RGD:9068941
G MTHFR methylenetetrahydrofolate reductase JBrowse link 6 71,863,637 71,882,118 RGD:9068941
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase JBrowse link 16 74,245,214 74,270,828 RGD:9068941
G NANOG Nanog homeobox JBrowse link 5 62,931,642 62,939,086 RGD:9068941
G NCAPG2 non-SMC condensin II complex subunit G2 JBrowse link 18 653,182 713,825 RGD:9068941
G ND1 NADH dehydrogenase subunit 1 JBrowse link MT 3,922 4,876 RGD:9068941
G ND2 NADH dehydrogenase subunit 2 JBrowse link MT 5,087 6,128 RGD:9068941
G ND3 NADH dehydrogenase subunit 3 JBrowse link MT 10,653 10,998 RGD:9068941
G ND4 NADH dehydrogenase subunit 4 JBrowse link MT 11,359 12,736 RGD:9068941
G NDUFA13 NADH:ubiquinone oxidoreductase subunit A13 JBrowse link 2 58,401,542 58,410,414 RGD:9068941
G NDUFB8 NADH:ubiquinone oxidoreductase subunit B8 JBrowse link 14 111,626,827 111,633,548 RGD:9068941
G NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 JBrowse link 15 109,413,726 109,451,813 RGD:9068941
G NDUFS4 NADH:ubiquinone oxidoreductase subunit S4 JBrowse link 16 32,874,418 32,985,638 RGD:9068941
G NDUFV2 NADH:ubiquinone oxidoreductase core subunit V2 JBrowse link 6 98,819,156 98,852,561 RGD:9068941
G NECTIN2 nectin cell adhesion molecule 2 JBrowse link 6 51,317,386 51,358,665 RGD:9068941
G NEDD8 NEDD8 ubiquitin like modifier JBrowse link 7 75,069,947 75,085,905 RGD:9068941
G NGF nerve growth factor JBrowse link 4 105,256,691 105,307,843 RGD:9068941
G NGFR nerve growth factor receptor JBrowse link 12 25,699,410 25,720,355 RGD:9068941
G NOS1 nitric oxide synthase 1 JBrowse link 14 35,112,898 35,299,297 RGD:9068941
G NOS2 nitric oxide synthase 2 JBrowse link 12 44,174,944 44,219,875 RGD:9068941
G NQO1 NAD(P)H quinone dehydrogenase 1 JBrowse link 6 17,292,962 17,302,593 RGD:9068941
G NQO2 N-ribosyldihydronicotinamide:quinone reductase 2 JBrowse link 7 1,792,745 1,805,916 RGD:9068941
G NR4A2 nuclear receptor subfamily 4 group A member 2 JBrowse link 15 63,487,051 63,506,249 RGD:9068941
G NTSR1 neurotensin receptor 1 JBrowse link 17 61,989,601 62,038,299 RGD:9068941
G OGG1 8-oxoguanine DNA glycosylase JBrowse link 13 66,038,669 66,045,478 RGD:9068941
G OPTN optineurin JBrowse link 10 48,532,029 48,582,952 RGD:9068941
G ORC6 origin recognition complex subunit 6 JBrowse link 6 37,934,903 37,943,950 RGD:9068941
G PARK7 Parkinsonism associated deglycase JBrowse link 6 68,629,327 68,645,147 RGD:9068941
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 10 14,203,157 14,241,164 RGD:9068941
G PENK proenkephalin JBrowse link 4 75,525,497 75,530,403 RGD:9068941
G PHACTR2 phosphatase and actin regulator 2 JBrowse link 1 21,438,744 21,723,255 RGD:9068941
G PINK1 PTEN induced kinase 1 JBrowse link 6 78,863,195 78,884,663 RGD:9068941
G PITX3 paired like homeodomain 3 JBrowse link 14 113,230,194 113,241,393 RGD:9068941
G PLA2G6 phospholipase A2 group VI JBrowse link 5 9,713,809 9,777,921 RGD:9068941
G POLG DNA polymerase gamma, catalytic subunit JBrowse link 7 54,889,150 54,907,167 RGD:9068941
G PPARGC1A PPARG coactivator 1 alpha JBrowse link 8 17,841,844 18,527,953 RGD:9068941
G PPP1R9B protein phosphatase 1 regulatory subunit 9B JBrowse link 12 26,319,123 26,337,089 RGD:9068941
G PPP2CA protein phosphatase 2 catalytic subunit alpha JBrowse link 2 136,497,780 136,522,630 RGD:9068941
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 1 5,698,508 6,731,132 RGD:9068941
G PTN pleiotrophin JBrowse link 18 12,219,708 12,309,045 RGD:9068941
G RPL23A ribosomal protein L23a JBrowse link 12 44,956,851 44,960,737 RGD:9068941
G RPL6 ribosomal protein L6 JBrowse link 14 39,302,447 39,309,239 RGD:9068941
G RPS8 ribosomal protein S8 JBrowse link 6 166,550,574 166,553,289 RGD:9068941
G RRN3 RRN3 homolog, RNA polymerase I transcription factor JBrowse link 3 7,537,131 7,571,990 RGD:9068941
G S100B S100 calcium binding protein B RGD:9068941
G SDHA succinate dehydrogenase complex flavoprotein subunit A JBrowse link 16 79,838,442 79,862,956 RGD:9068941
G SEPTIN14 septin 14 JBrowse link 3 16,988,590 17,026,258 RGD:9068941
G SEPTIN4 septin 4 JBrowse link 12 34,772,776 34,785,176 RGD:9068941
G SLA-DRA MHC class II DR-alpha JBrowse link 7 24,825,037 24,830,650 RGD:9068941
G SLA-DRB1 MHC class II histocompatibility antigen SLA-DRB1 JBrowse link 7 24,901,386 24,914,016 RGD:9068941
G SLC11A2 solute carrier family 11 member 2 RGD:9068941
G SLC18A2 solute carrier family 18 member A2 JBrowse link 14 127,357,605 127,394,242 RGD:9068941
G SLC30A10 solute carrier family 30 member 10 JBrowse link 10 9,527,523 9,545,493 RGD:9068941
G SLC6A3 solute carrier family 6 member 3 JBrowse link 16 79,186,114 79,220,302 RGD:9068941
G SNCA synuclein alpha JBrowse link 8 129,247,724 129,388,307 RGD:9068941
G SNCAIP synuclein alpha interacting protein JBrowse link 2 125,889,165 125,956,864 RGD:9068941
G SNCB synuclein beta JBrowse link 2 81,287,764 81,302,859 RGD:9068941
G SNCG synuclein gamma JBrowse link 14 87,916,353 87,922,111 RGD:9068941
G SOD1 superoxide dismutase 1 JBrowse link 13 195,326,573 195,335,273 RGD:9068941
G SOD2 superoxide dismutase 2 JBrowse link 1 7,679,352 7,689,564 RGD:9068941
G SPR sepiapterin reductase JBrowse link 3 69,889,448 69,894,747 RGD:9068941
G SRRM2 serine/arginine repetitive matrix 2 JBrowse link 3 39,275,274 39,293,741 RGD:9068941
G SYNJ1 synaptojanin 1 JBrowse link 13 196,230,101 196,330,512 RGD:9068941
G TALDO1 transaldolase 1 JBrowse link 2 464,781 472,836 RGD:9068941
G TARDBP TAR DNA binding protein JBrowse link 6 71,213,584 71,227,707 RGD:9068941
G TCL1B T cell leukemia/lymphoma 1B JBrowse link 7 116,912,974 116,917,940 RGD:9068941
G TCN2 transcobalamin 2 JBrowse link 14 47,496,245 47,515,966 RGD:9068941
G TDGF1 teratocarcinoma-derived growth factor 1 JBrowse link 13 29,537,874 29,544,686 RGD:9068941
G TFAM transcription factor A, mitochondrial JBrowse link 14 92,261,713 92,279,731 RGD:9068941
G TH tyrosine hydroxylase JBrowse link 2 1,499,628 1,506,180 RGD:9068941
G TMEM230 transmembrane protein 230 JBrowse link 17 14,125,728 14,136,443 RGD:9068941
G TNF tumor necrosis factor JBrowse link 7 23,699,635 23,702,393 RGD:9068941
G TNFRSF1B TNF receptor superfamily member 1B JBrowse link 6 72,195,420 72,231,146 RGD:9068941
G TNK2 tyrosine kinase non receptor 2 JBrowse link 13 134,082,266 134,124,826 RGD:9068941
G TNR tenascin R JBrowse link 9 117,365,930 117,790,332 RGD:9068941
G TRPM2 transient receptor potential cation channel subfamily M member 2 JBrowse link 13 207,212,339 207,263,313 RGD:9068941
G TWNK twinkle mtDNA helicase JBrowse link 14 112,068,463 112,076,169 RGD:9068941
G UCHL1 ubiquitin C-terminal hydrolase L1 JBrowse link 8 32,353,766 32,367,288 RGD:9068941
G VDAC1 voltage dependent anion channel 1 JBrowse link 2 136,302,188 136,334,461 RGD:9068941
G VDR vitamin D receptor JBrowse link 5 78,205,807 78,266,505 RGD:9068941
G VIP vasoactive intestinal peptide JBrowse link 1 13,611,786 13,620,250 RGD:9068941
G VPS13C vacuolar protein sorting 13 homolog C JBrowse link 1 109,931,269 110,105,519 RGD:9068941
G VPS35 VPS35 retromer complex component JBrowse link 6 37,944,099 37,977,091 RGD:9068941
amyotrophic lateral sclerosis-parkinsonism/dementia complex 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TRPM7 transient receptor potential cation channel subfamily M member 7 JBrowse link 1 121,146,093 121,250,227 RGD:7240710
RGD:9068941
Early Onset Parkinsonism with Mental Retardation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CLIC2 chloride intracellular channel 2 JBrowse link X 125,546,451 125,560,059 RGD:9068941
G RAB39B RAB39B, member RAS oncogene family JBrowse link X 125,520,764 125,528,253 RGD:7240710
RGD:9068941
Kufor-Rakeb syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP13A2 ATPase cation transporting 13A2 JBrowse link 6 75,618,317 75,638,591 RGD:7240710
RGD:9068941
late onset Parkinson's disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATXN2 ataxin 2 JBrowse link 14 32,656,537 32,772,082 RGD:7240710
RGD:9068941
G DBH dopamine beta-hydroxylase JBrowse link 1 273,204,407 273,225,562 RGD:9068941
G DNAJC13 DnaJ heat shock protein family (Hsp40) member C13 JBrowse link 13 73,573,887 73,707,951 RGD:9068941
G EIF4G1 eukaryotic translation initiation factor 4 gamma 1 JBrowse link 13 122,203,488 122,225,371 RGD:7240710
RGD:9068941
G FGF20 fibroblast growth factor 20 JBrowse link 17 4,691,448 4,700,367 RGD:9068941
G GBA glucosylceramidase beta JBrowse link 4 94,583,905 94,606,689 RGD:7240710
RGD:9068941
G LOC100739163 glutathione S-transferase P-like JBrowse link 2 4,978,761 4,982,233 RGD:9068941
G LRRK2 leucine rich repeat kinase 2 JBrowse link 5 71,800,337 71,945,828 RGD:9068941
G MAPT microtubule associated protein tau JBrowse link 12 17,098,259 17,211,483 RGD:7240710
RGD:9068941
G MC1R melanocortin 1 receptor JBrowse link 6 181,225 182,187 RGD:9068941
G ND1 NADH dehydrogenase subunit 1 JBrowse link MT 3,922 4,876 RGD:9068941
G NR4A2 nuclear receptor subfamily 4 group A member 2 JBrowse link 15 63,487,051 63,506,249 RGD:9068941
G PARK7 Parkinsonism associated deglycase JBrowse link 6 68,629,327 68,645,147 RGD:9068941
G PINK1 PTEN induced kinase 1 JBrowse link 6 78,863,195 78,884,663 RGD:9068941
G PODXL podocalyxin like JBrowse link 18 17,444,339 17,494,507 RGD:9068941
G SLA-DRA MHC class II DR-alpha JBrowse link 7 24,825,037 24,830,650 RGD:9068941
G SNCAIP synuclein alpha interacting protein JBrowse link 2 125,889,165 125,956,864 RGD:9068941
G TBP TATA-box binding protein JBrowse link 1 5,669 23,675 RGD:7240710
RGD:9068941
G UCHL1 ubiquitin C-terminal hydrolase L1 JBrowse link 8 32,353,766 32,367,288 RGD:7240710
RGD:9068941
G VPS35 VPS35 retromer complex component JBrowse link 6 37,944,099 37,977,091 RGD:9068941
Parkinson's disease 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SNCA synuclein alpha JBrowse link 8 129,247,724 129,388,307 RGD:7240710
RGD:9068941
Parkinson's Disease 11 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GIGYF2 GRB10 interacting GYF protein 2 JBrowse link 15 133,180,638 133,313,307 RGD:7240710
RGD:9068941
Parkinson's Disease 13 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HTRA2 HtrA serine peptidase 2 JBrowse link 3 68,516,666 68,520,025 RGD:7240710
RGD:9068941
G LOXL3 lysyl oxidase like 3 JBrowse link 3 68,498,114 68,516,829 RGD:9068941
Parkinson's disease 14 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PLA2G6 phospholipase A2 group VI JBrowse link 5 9,713,809 9,777,921 RGD:7240710
RGD:9068941
Parkinson's disease 15 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FBXO7 F-box protein 7 JBrowse link 5 12,505,646 12,526,206 RGD:7240710
RGD:9068941
Parkinson's disease 17 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G VPS35 VPS35 retromer complex component JBrowse link 6 37,944,099 37,977,091 RGD:7240710
RGD:9068941
Parkinson's disease 19A term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DNAJC6 DnaJ heat shock protein family (Hsp40) member C6 JBrowse link 6 146,990,115 147,161,010 RGD:7240710
RGD:9068941
Parkinson's disease 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PACRG parkin coregulated JBrowse link 1 4,964,686 5,465,258 RGD:9068941
G PODXL podocalyxin like JBrowse link 18 17,444,339 17,494,507 RGD:9068941
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 1 5,698,508 6,731,132 RGD:7240710
RGD:9068941
Parkinson's disease 20 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CFAP298 cilia and flagella associated protein 298 JBrowse link 13 196,210,006 196,225,395 RGD:9068941
G SYNJ1 synaptojanin 1 JBrowse link 13 196,230,101 196,330,512 RGD:7240710
RGD:9068941
Parkinson's disease 21 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DNAJC13 DnaJ heat shock protein family (Hsp40) member C13 JBrowse link 13 73,573,887 73,707,951 RGD:7240710
RGD:9068941
Parkinson's disease 22 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 JBrowse link 3 16,812,409 16,819,130 RGD:7240710
RGD:9068941
Parkinson's disease 23 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G VPS13C vacuolar protein sorting 13 homolog C JBrowse link 1 109,931,269 110,105,519 RGD:7240710
RGD:9068941
Parkinson's disease 4 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SNCA synuclein alpha JBrowse link 8 129,247,724 129,388,307 RGD:7240710
RGD:9068941
Parkinson's Disease 5 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G UCHL1 ubiquitin C-terminal hydrolase L1 JBrowse link 8 32,353,766 32,367,288 RGD:9068941
Parkinson's disease 6 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MTFP1 mitochondrial fission process 1 JBrowse link 14 47,392,578 47,396,115 RGD:9068941
G ND5 NADH dehydrogenase subunit 5 JBrowse link MT 12,935 14,755 RGD:9068941
G ND6 NADH dehydrogenase subunit 6 JBrowse link MT 14,739 15,266 RGD:9068941
G PARK7 Parkinsonism associated deglycase JBrowse link 6 68,629,327 68,645,147 RGD:9068941
G PINK1 PTEN induced kinase 1 JBrowse link 6 78,863,195 78,884,663 RGD:7240710
RGD:9068941
Parkinson's disease 7 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARK7 Parkinsonism associated deglycase JBrowse link 6 68,629,327 68,645,147 RGD:7240710
RGD:9068941
Parkinson's disease 8 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LRRK2 leucine rich repeat kinase 2 JBrowse link 5 71,800,337 71,945,828 RGD:7240710
RGD:9068941
Parkinson's Disease, Mitochondrial term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FMC1 formation of mitochondrial complex V assembly factor 1 homolog JBrowse link 18 10,346,029 10,350,372 RGD:9068941
G NDUFV2 NADH:ubiquinone oxidoreductase core subunit V2 JBrowse link 6 98,819,156 98,852,561 RGD:9068941
Parkinson's Disease, X-Linked Dominant term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RAB39B RAB39B, member RAS oncogene family JBrowse link X 125,520,764 125,528,253 RGD:9068941
Parkinsonism with Spasticity, X-Linked term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP6AP2 ATPase H+ transporting accessory protein 2 JBrowse link X 36,271,154 36,300,240 RGD:7240710
RGD:9068941
G G6PD glucose-6-phosphate dehydrogenase JBrowse link X 125,029,147 125,041,040 RGD:9068941
Parkinsonism-Dystonia, Infantile term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SLC6A3 solute carrier family 6 member 3 JBrowse link 16 79,186,114 79,220,302 RGD:9068941
Parkinsonism-Dystonia, Infantile, 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SLC6A3 solute carrier family 6 member 3 JBrowse link 16 79,186,114 79,220,302 RGD:7240710
RGD:9068941
Parkinsonism-Dystonia, Infantile, 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SLC18A2 solute carrier family 18 member A2 JBrowse link 14 127,357,605 127,394,242 RGD:7240710
RGD:9068941
Progressive Supranuclear Palsy Atypical term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MAPT microtubule associated protein tau JBrowse link 12 17,098,259 17,211,483 RGD:7240710
RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 12055
    disease of anatomical entity 11715
      nervous system disease 9412
        neurodegenerative disease 2768
          synucleinopathy 257
            Parkinson's disease 233
              Parkinson's Disease 10 0
              Parkinson's Disease 11 1
              Parkinson's Disease 12 0
              Parkinson's Disease 13 2
              Parkinson's Disease 16 0
              Parkinson's Disease 5 1
              Parkinson's Disease, Mitochondrial 2
              Parkinson's Disease, X-Linked Dominant 1
              Parkinsonism with Spasticity, X-Linked 2
              Parkinsonism-Dystonia, Infantile + 2
              Progressive Supranuclear Palsy Atypical 1
              amyotrophic lateral sclerosis-parkinsonism/dementia complex 1 1
              early-onset Parkinson's disease + 16
              late onset Parkinson's disease + 23
Path 2
Term Annotations click to browse term
  disease 12055
    disease of anatomical entity 11715
      nervous system disease 9412
        central nervous system disease 7827
          brain disease 7218
            basal ganglia disease 511
              Parkinsonian Disorders 306
                Parkinson's disease 233
                  Parkinson's Disease 10 0
                  Parkinson's Disease 11 1
                  Parkinson's Disease 12 0
                  Parkinson's Disease 13 2
                  Parkinson's Disease 16 0
                  Parkinson's Disease 5 1
                  Parkinson's Disease, Mitochondrial 2
                  Parkinson's Disease, X-Linked Dominant 1
                  Parkinsonism with Spasticity, X-Linked 2
                  Parkinsonism-Dystonia, Infantile + 2
                  Progressive Supranuclear Palsy Atypical 1
                  amyotrophic lateral sclerosis-parkinsonism/dementia complex 1 1
                  early-onset Parkinson's disease + 16
                  late onset Parkinson's disease + 23
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.