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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:colon carcinoma
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Accession:DOID:1520 term browser browse the term
Definition:A colon cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells. (DO)
Synonyms:exact_synonym: carcinoma of colon;   colonic carcinoma
 primary_id: RDO:9002019
 xref: NCI:C4910
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
colon carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 thymoma viral proto-oncogene 1 ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:17611497, PMID:18256540, PMID:18392055, PMID:18504432, PMID:18611285, PMID:19418217, PMID:19487299, PMID:19853286, PMID:20233444, PMID:20453058, PMID:21464312, PMID:21512767, PMID:21793738, PMID:22538770, PMID:22610119, PMID:22722201, PMID:22722839, PMID:22980975, PMID:23237847, PMID:23348505, PMID:23700467, PMID:23728071, PMID:23934607, PMID:24190505, PMID:24657128, PMID:25157968, PMID:26619011, PMID:28492532 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884
JBrowse link
G Apc APC, WNT signaling pathway regulator ISO ClinVar Annotator: match by term: Colonic carcinoma
ClinVar Annotator: match by term: Carcinoma of colon
ClinVar PMID:1338904, PMID:1528264, PMID:8187091, PMID:8381579, PMID:8940262, PMID:9288102, PMID:9585599, PMID:9724771, PMID:9731522, PMID:9731533, PMID:9751605, PMID:9831355, PMID:9869602, PMID:9869603, PMID:9869620, PMID:9950360, PMID:9973276, PMID:10439961, PMID:10679643, PMID:10737795, PMID:10938175, PMID:11001924, PMID:11159880, PMID:11207040, PMID:11354631, PMID:12173321, PMID:12533824, PMID:14624392, PMID:14633595, PMID:15712637, PMID:15929773, PMID:16140997, PMID:16228836, PMID:16569251, PMID:16875934, PMID:17854661, PMID:18343606, PMID:19047896, PMID:19768578, PMID:20223039, PMID:20685668, PMID:22703879, PMID:22810696, PMID:23204322, PMID:23576677, PMID:23896379, PMID:24033266, PMID:24310308, PMID:24416237, PMID:24599579, PMID:24728327, PMID:24861525, PMID:25157968, PMID:25604157, PMID:25741868, PMID:25980754, PMID:25981591, PMID:26187149, PMID:26300997, PMID:26314409, PMID:26332594, PMID:26394139, PMID:26421687, PMID:26467025, PMID:26625971, PMID:26845104, PMID:27146957, PMID:27153395, PMID:27978560, PMID:28050010, PMID:28135136, PMID:28135145, PMID:28492532, PMID:28749474, PMID:29478780, PMID:29506128, PMID:29961768, PMID:30152102, PMID:30426508, PMID:30487145 NCBI chr18:34,220,297...34,322,190
Ensembl chr18:34,220,924...34,322,552
JBrowse link
G Axin2 axin 2 ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:11017067, PMID:28492532 NCBI chr11:108,917,828...108,950,783
Ensembl chr11:108,920,349...108,950,783
JBrowse link
G Bard1 BRCA1 associated RING domain 1 ISO ClinVar Annotator: match by term: Carcinoma of colon ClinVar PMID:25741868, PMID:26350354, PMID:28135145, PMID:28492532, PMID:31371347 NCBI chr 1:71,027,535...71,103,141
Ensembl chr 1:71,027,498...71,103,146
JBrowse link
G Bax BCL2-associated X protein ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:9020077 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Bcl10 B cell leukemia/lymphoma 10 ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:9989495 NCBI chr 3:145,924,262...145,934,366
Ensembl chr 3:145,922,804...145,934,356
JBrowse link
G Braf Braf transforming gene treatment ISO ClinVar Annotator: match by term: Colonic carcinoma
ClinVar Annotator: match by term: Carcinoma of colon
ClinVar PMID:12068308, PMID:12198537, PMID:12447372, PMID:12460918, PMID:12460919, PMID:12619120, PMID:12644542, PMID:12670889, PMID:12692057, PMID:12794760, PMID:12960123, PMID:14513361, PMID:14602780, PMID:14679157, PMID:15001635, PMID:15035987, PMID:15126572, PMID:15181070, PMID:15342696, PMID:15356022, PMID:15386408, PMID:15687339, PMID:15998781, PMID:16015629, PMID:16174717, PMID:16187918, PMID:16772349, PMID:17374713, PMID:17488796, PMID:17704260, PMID:17785355, PMID:18039235, PMID:18060073, PMID:18398503, PMID:18413255, PMID:19001320, PMID:19010912, PMID:19018267, PMID:19238210, PMID:19404918, PMID:19537845, PMID:19561230, PMID:20008640, PMID:20350999, PMID:20413299, PMID:20619739, PMID:20630094, PMID:20818844, PMID:20823850, PMID:20857202, PMID:21107320, PMID:21107323, PMID:21129611, PMID:21156289, PMID:21163703, PMID:21426297, PMID:21483012, PMID:21502544, PMID:21639808, PMID:21641636, PMID:21683865, PMID:21975775, PMID:22038996, PMID:22048237, PMID:22113612, PMID:22180495, PMID:22281684, PMID:22351686, PMID:22356324, PMID:22389471, PMID:22448344, PMID:22536370, PMID:22586120, PMID:22608338, PMID:22649091, PMID:22663011, PMID:22735384, PMID:22743296, PMID:22773810, PMID:22805292, PMID:22972589, PMID:22997239, PMID:23020132, PMID:23031422, PMID:23251002, PMID:23302800, PMID:23325582, PMID:23470635, PMID:23524406, PMID:23549875, PMID:23614898, PMID:23680146, PMID:23685455, PMID:23812671, PMID:23833300, PMID:23845441, PMID:23918947, PMID:24033266, PMID:24107445, PMID:24112392, PMID:24163374, PMID:24388723, PMID:24508103, PMID:24512911, PMID:24576830, PMID:24583796, PMID:24586605, PMID:24594804, PMID:24670642, PMID:24717435, PMID:25024077, PMID:25037139, PMID:25079330, PMID:25155755, PMID:25157968, PMID:25265492, PMID:25265494, PMID:25370471, PMID:25399551, PMID:25741868, PMID:25950823, PMID:25989278, PMID:26619011, PMID:26678033, PMID:27404270, PMID:27480103, PMID:28492532, PMID:28854169, PMID:28891408, PMID:29925953, PMID:31779674, PMID:31891627, PMID:22319199 RGD:11567267 NCBI chr 6:39,603,231...39,725,658
Ensembl chr 6:39,603,237...39,725,463
JBrowse link
G Brca2 breast cancer 2, early onset ISO ClinVar Annotator: match by term: Colonic carcinoma
ClinVar Annotator: match by term: Carcinoma of colon
ClinVar PMID:15937982, PMID:16758124, PMID:20167696, PMID:21520333, PMID:24814045, PMID:25058500, PMID:25348012, PMID:25741868, PMID:27165003, PMID:28223274, PMID:28492532, PMID:29394989, PMID:29849630, PMID:29881398, PMID:29884841, PMID:30254663 NCBI chr 5:150,522,297...150,570,147
Ensembl chr 5:150,522,630...150,570,329
JBrowse link
G Brip1 BRCA1 interacting protein C-terminal helicase 1 ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:21964575, PMID:25058500, PMID:25741868, PMID:27165003, PMID:28492532 NCBI chr11:86,058,136...86,201,215
Ensembl chr11:86,058,138...86,201,193
JBrowse link
G Bub1 BUB1, mitotic checkpoint serine/threonine kinase ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:9521327 NCBI chr 2:127,800,197...127,831,859
Ensembl chr 2:127,801,122...127,831,865
JBrowse link
G Bub1b BUB1B, mitotic checkpoint serine/threonine kinase ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:9521327, PMID:24728327, PMID:28492532 NCBI chr 2:118,598,202...118,641,592
Ensembl chr 2:118,598,211...118,641,591
JBrowse link
G Crkl v-crk avian sarcoma virus CT10 oncogene homolog-like ISO RGD PMID:16391854 RGD:7488899 NCBI chr16:17,451,985...17,487,440
Ensembl chr16:17,451,987...17,487,434
JBrowse link
G Ctnnb1 catenin (cadherin associated protein), beta 1 ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:9065402, PMID:9294210, PMID:10192393, PMID:25157968, PMID:26619011, PMID:26822237 NCBI chr 9:120,933,400...120,960,507
Ensembl chr 9:120,929,216...120,960,507
JBrowse link
G Cxcl10 chemokine (C-X-C motif) ligand 10 treatment IDA RGD PMID:30381616 RGD:27095891 NCBI chr 5:92,346,638...92,348,889
Ensembl chr 5:92,346,638...92,348,889
JBrowse link
G Cxcl5 chemokine (C-X-C motif) ligand 5 disease_progression ISO RGD PMID:18413816 RGD:5135268 NCBI chr 5:90,759,298...90,761,625
Ensembl chr 5:90,759,360...90,761,624
JBrowse link
G Dcc deleted in colorectal carcinoma ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:8188295 NCBI chr18:71,253,613...72,351,228
Ensembl chr18:71,253,634...72,351,069
JBrowse link
G Dlc1 deleted in liver cancer 1 ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:10649492 NCBI chr 8:36,567,739...36,953,184
Ensembl chr 8:36,567,751...36,953,143
JBrowse link
G Ep300 E1A binding protein p300 ISO ClinVar Annotator: match by term: Colonic carcinoma
ClinVar Annotator: match by term: Carcinoma of colon
ClinVar PMID:10700188, PMID:28492532 NCBI chr15:81,586,209...81,652,077
Ensembl chr15:81,585,351...81,652,077
JBrowse link
G Fancc Fanconi anemia, complementation group C ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:25058500, PMID:27165003 NCBI chr13:63,301,334...63,497,292
Ensembl chr13:63,285,043...63,497,278
JBrowse link
G Fance Fanconi anemia, complementation group E ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:25058500, PMID:27165003, PMID:28492532 NCBI chr17:28,313,530...28,326,574
Ensembl chr17:28,313,519...28,326,572
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:1908846, PMID:7773297, PMID:8589699, PMID:8858131, PMID:9677066, PMID:10073901, PMID:10471491, PMID:10696568, PMID:11038465, PMID:11241532, PMID:11529856, PMID:11879084, PMID:11906172, PMID:12833394, PMID:15772091, PMID:16841094, PMID:17384684, PMID:18642369, PMID:19381019, PMID:19749790, PMID:25157968, PMID:25606676, PMID:25741868, PMID:26619011, PMID:28492532, PMID:30311386 NCBI chr 5:33,721,724...33,737,068
Ensembl chr 5:33,721,674...33,737,068
JBrowse link
G Flcn folliculin ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:12843323, PMID:15805188, PMID:15852235, PMID:18234728, PMID:19457309, PMID:19802896, PMID:20618353, PMID:21937013, PMID:22703879, PMID:23050938, PMID:24033266, PMID:24393238, PMID:24728327, PMID:25594584, PMID:25741868, PMID:28492532, PMID:28558743 NCBI chr11:59,791,408...59,810,039
Ensembl chr11:59,791,408...59,810,016
JBrowse link
G Flt1 FMS-like tyrosine kinase 1 ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar NCBI chr 5:147,561,604...147,726,438
Ensembl chr 5:147,561,604...147,726,011
JBrowse link
G Flt3l FMS-like tyrosine kinase 3 ligand treatment ISO RGD PMID:10842197 RGD:11049504 NCBI chr 7:45,131,183...45,136,490
Ensembl chr 7:45,129,788...45,136,432
JBrowse link
G Flt4 FMS-like tyrosine kinase 4 ISO ClinVar Annotator: match by term: Colonic carcinoma
ClinVar Annotator: match by term: Carcinoma of colon
ClinVar PMID:11807987, PMID:25741868, PMID:28492532 NCBI chr11:49,609,679...49,652,739
Ensembl chr11:49,609,263...49,652,739
JBrowse link
G Hpgd hydroxyprostaglandin dehydrogenase 15 (NAD) ISO DNA:::adenoviral delivery of human gene in mouse model of colon cancer RGD PMID:19494278 RGD:5688759 NCBI chr 8:56,294,552...56,321,046
Ensembl chr 8:56,294,585...56,321,043
JBrowse link
G Igf2r insulin-like growth factor 2 receptor ISO protein:increased expression:serum: RGD PMID:29940770 RGD:14985218 NCBI chr17:12,682,406...12,769,706
Ensembl chr17:12,682,406...12,769,664
JBrowse link
G Kdr kinase insert domain protein receptor ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar NCBI chr 5:75,932,827...75,979,072
Ensembl chr 5:75,932,827...75,978,458
JBrowse link
G Mcc mutated in colorectal cancers ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:1848370 NCBI chr18:44,425,060...44,812,182
Ensembl chr18:44,425,060...44,812,182
JBrowse link
G Mlh1 mutL homolog 1 ISO ClinVar Annotator: match by term: Carcinoma of colon ClinVar PMID:10495924, PMID:11555625, PMID:11781295, PMID:11948175, PMID:12386821, PMID:12547705, PMID:12658575, PMID:14699485, PMID:15713769, PMID:15731775, PMID:15849733, PMID:15926618, PMID:16995940, PMID:17054581, PMID:17135187, PMID:17210669, PMID:17312306, PMID:17510385, PMID:18205192, PMID:18561205, PMID:19419416, PMID:19698169, PMID:20020535, PMID:20587412, PMID:20682701, PMID:20864636, PMID:21404117, PMID:21952876, PMID:22703879, PMID:22736432, PMID:22753075, PMID:22949379, PMID:24033266, PMID:24344984, PMID:24362816, PMID:25741868, PMID:26247049, PMID:28445943, PMID:28492532 NCBI chr 9:111,228,228...111,271,786
Ensembl chr 9:111,228,228...111,271,791
JBrowse link
G Mlh3 mutL homolog 3 ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:11317354 NCBI chr12:85,234,466...85,270,647
Ensembl chr12:85,234,520...85,270,599
JBrowse link
G Msh2 mutS homolog 2 ISO ClinVar Annotator: match by term: Carcinoma of colon ClinVar PMID:8062247, PMID:8261515, PMID:9288790, PMID:9718327, PMID:10793088, PMID:12362047, PMID:14970868, PMID:15713769, PMID:15731775, PMID:15849733, PMID:17312306, PMID:17414604, PMID:19459153, PMID:19698169, PMID:20223024, PMID:20591884, PMID:21239990, PMID:21590452, PMID:24278394, PMID:24710284, PMID:25741868, PMID:26467025, PMID:27016151, PMID:28492532, PMID:29238914, PMID:30376427 NCBI chr17:87,672,532...87,723,713
Ensembl chr17:87,672,330...87,723,713
JBrowse link
G mt-Nd1 NADH dehydrogenase 1, mitochondrial ISO ClinVar Annotator: match by term: Carcinoma of colon ClinVar PMID:9299504, PMID:9806551, PMID:10519336, PMID:10521313, PMID:13298683, PMID:15972314 NCBI chr MT:2,751...3,707
Ensembl chr MT:2,751...3,707
JBrowse link
G Mutyh mutY DNA glycosylase ISO ClinVar Annotator: match by term: Colonic carcinoma
ClinVar Annotator: match by term: Carcinoma of colon
ClinVar PMID:11818965, PMID:12606733, PMID:14579148, PMID:14991577, PMID:15188161, PMID:15236166, PMID:15366000, PMID:15635083, PMID:15931596, PMID:15987719, PMID:16134147, PMID:16140997, PMID:16338133, PMID:16492921, PMID:16557584, PMID:16616356, PMID:16941501, PMID:17122612, PMID:17219385, PMID:17368238, PMID:17489848, PMID:17524638, PMID:17581577, PMID:17674103, PMID:17949294, PMID:17956577, PMID:18271935, PMID:18414213, PMID:18506705, PMID:18534194, PMID:19032956, PMID:19245865, PMID:19394335, PMID:19527492, PMID:19531215, PMID:19725997, PMID:19732775, PMID:19793053, PMID:19836313, PMID:19953527, PMID:19998059, PMID:20191381, PMID:20418187, PMID:20618354, PMID:20663686, PMID:20687945, PMID:20725929, PMID:20848659, PMID:21063410, PMID:21167187, PMID:21171015, PMID:21178863, PMID:21443744, PMID:21520333, PMID:21777424, PMID:21815886, PMID:21952991, PMID:22158503, PMID:22266422, PMID:22297469, PMID:22402879, PMID:22473953, PMID:22641385, PMID:22703879, PMID:22722201, PMID:22744763, PMID:22865608, PMID:22922830, PMID:22926731, PMID:22976915, PMID:23007840, PMID:23035301, PMID:23108399, PMID:23322991, PMID:23361220, PMID:23561487, PMID:23605219, PMID:23625202, PMID:23805267, PMID:24033266, PMID:24039736, PMID:24082139, PMID:24278394, PMID:24444654, PMID:24470512, PMID:24691292, PMID:24728327, PMID:24799981, PMID:24953332, PMID:25525159, PMID:25569433, PMID:25741868, PMID:25820570, PMID:25937855, PMID:25980754, PMID:26377631, PMID:26467025, PMID:26681312, PMID:26822237, PMID:26845104, PMID:26976419, PMID:27145315, PMID:27153395, PMID:27600092, PMID:27621404, PMID:27829682, PMID:28135145, PMID:28492532, PMID:28634180, PMID:28944238, PMID:30151275, PMID:30256826, PMID:30564557 NCBI chr 4:116,807,636...116,819,439
Ensembl chr 4:116,807,723...116,819,440
JBrowse link
G Nras neuroblastoma ras oncogene ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:2674680, PMID:3102434, PMID:8120410, PMID:16291983, PMID:18390968, PMID:18633438, PMID:20130576, PMID:20179705, PMID:22962325, PMID:23414587, PMID:25157968, PMID:26619011 NCBI chr 3:103,058,285...103,067,914
Ensembl chr 3:103,058,285...103,067,914
JBrowse link
G Palb2 partner and localizer of BRCA2 ISO ClinVar Annotator: match by term: Carcinoma of colon ClinVar PMID:18053174, PMID:25741868, PMID:26283626, PMID:26315354, PMID:26467025, PMID:26580448, PMID:26689913, PMID:28135145, PMID:28492532, PMID:28944238 NCBI chr 7:122,107,262...122,132,980
Ensembl chr 7:122,107,262...122,132,985
JBrowse link
G Pdgfrl platelet-derived growth factor receptor-like ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:7898930 NCBI chr 8:40,926,233...40,990,782
Ensembl chr 8:40,926,212...40,990,785
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:15016963, PMID:15254419, PMID:15520168, PMID:15608678, PMID:15647370, PMID:15805248, PMID:16906227, PMID:16930767, PMID:17376864, PMID:17673550, PMID:18676830, PMID:18725974, PMID:19029981, PMID:19223544, PMID:19366826, PMID:19513541, PMID:19903786, PMID:20453058, PMID:20619739, PMID:21430269, PMID:21558396, PMID:21824802, PMID:22162582, PMID:22162589, PMID:22271473, PMID:22658544, PMID:22729222, PMID:22729223, PMID:22729224, PMID:23066039, PMID:23100325, PMID:23888070, PMID:24033266, PMID:24265155, PMID:24782230, PMID:25157968, PMID:25741868, PMID:26266975, PMID:26266985, PMID:26619011, PMID:26822237, PMID:27626068, PMID:27631024, PMID:28492532 NCBI chr 3:32,397,065...32,466,112
Ensembl chr 3:32,397,671...32,468,486
JBrowse link
G Pold1 polymerase (DNA directed), delta 1, catalytic subunit ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:25637381, PMID:25741868, PMID:26467025, PMID:28492532 NCBI chr 7:44,532,744...44,548,815
Ensembl chr 7:44,532,746...44,548,849
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:10394368 NCBI chr 6:115,360,879...115,490,404
Ensembl chr 6:115,360,951...115,490,399
JBrowse link
G Prf1 perforin 1 (pore forming protein) ISO RGD PMID:22420317 RGD:6482822 NCBI chr10:61,297,751...61,304,684
Ensembl chr10:61,297,833...61,304,680
JBrowse link
G Ptpn12 protein tyrosine phosphatase, non-receptor type 12 ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:7509295 NCBI chr 5:20,986,645...21,055,911
Ensembl chr 5:20,986,645...21,055,911
JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:12089527 NCBI chr 2:90,429,756...90,580,694
Ensembl chr 2:90,429,754...90,580,647
JBrowse link
G Rad54b RAD54 homolog B (S. cerevisiae) ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:10362364 NCBI chr 4:11,558,920...11,615,808
Ensembl chr 4:11,558,922...11,615,805
JBrowse link
G Rev3l REV3 like, DNA directed polymerase zeta catalytic subunit ISO ClinVar Annotator: match by term: Colonic carcinoma ClinVar PMID:25058500, PMID:27165003 NCBI chr10:39,731,561...39,875,211
Ensembl chr10:39,732,118...39,875,211
JBrowse link
G Tgfb1 transforming growth factor, beta 1 disease_progression ISO RGD PMID:11166150 RGD:13432074 NCBI chr 7:25,687,002...25,705,077
Ensembl chr 7:25,687,002...25,705,077
JBrowse link
G Tgfb2 transforming growth factor, beta 2 disease_progression ISO
IGI
RGD PMID:11166150, PMID:10416598 RGD:13432074, RGD:13432084 NCBI chr 1:186,622,787...186,709,697
Ensembl chr 1:186,622,792...186,705,989
JBrowse link
G Tlr3 toll-like receptor 3 ISO protein:increased expression:colon RGD PMID:23467704 RGD:21079438 NCBI chr 8:45,395,665...45,411,075
Ensembl chr 8:45,395,665...45,411,080
JBrowse link
G Tnfrsf17 tumor necrosis factor receptor superfamily, member 17 ISO RGD PMID:11104810 RGD:2317311 NCBI chr16:11,313,232...11,320,074
Ensembl chr16:11,313,812...11,320,074
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a IEP protein:increased expression:serum (human) RGD PMID:1655258 RGD:5131434 NCBI chr 6:125,349,723...125,362,483
Ensembl chr 6:125,349,362...125,362,484
JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b ISO protein:increased expression:serum (human) RGD PMID:1655258 RGD:5131434 NCBI chr 4:145,212,368...145,246,870
Ensembl chr 4:145,213,463...145,246,870
JBrowse link
G Trp53 transformation related protein 53 ISO ClinVar Annotator: match by term: Colonic carcinoma
ClinVar Annotator: match by term: Carcinoma of colon
ClinVar PMID:1565143, PMID:1565144, PMID:1683921, PMID:1978757, PMID:7732013, PMID:7887414, PMID:8164043, PMID:8198984, PMID:8203469, PMID:8423216, PMID:8825920, PMID:9047394, PMID:9242456, PMID:9290701, PMID:9569050, PMID:9865903, PMID:10064694, PMID:10411893, PMID:10797439, PMID:10864200, PMID:11040944, PMID:11101847, PMID:11139324, PMID:11180592, PMID:11391594, PMID:11479205, PMID:11782540, PMID:11920959, PMID:12007217, PMID:12619118, PMID:12672316, PMID:12826609, PMID:15004724, PMID:15173255, PMID:15381368, PMID:15390294, PMID:15580553, PMID:15607980, PMID:15607981, PMID:15825182, PMID:15925506, PMID:15951970, PMID:15977174, PMID:16401470, PMID:16489069, PMID:16682957, PMID:16818505, PMID:17224268, PMID:17289876, PMID:17540308, PMID:17606709, PMID:17636407, PMID:17727479, PMID:18391940, PMID:18511570, PMID:18555592, PMID:19127115, PMID:19367569, PMID:19556618, PMID:19881536, PMID:20113312, PMID:20128691, PMID:20407015, PMID:20516128, PMID:20689556, PMID:20693561, PMID:21187651, PMID:21232794, PMID:21305319, PMID:21343334, PMID:21484931, PMID:21512767, PMID:21519010, PMID:21552135, PMID:21601526, PMID:21761402, PMID:22006311, PMID:22110706, PMID:22186996, PMID:22233476, PMID:22652532, PMID:22698404, PMID:22710932, PMID:22811390, PMID:22899716, PMID:22915647, PMID:22919068, PMID:23161690, PMID:23246812, PMID:23263379, PMID:23484829, PMID:23538418, PMID:23792586, PMID:23894400, PMID:24033266, PMID:24381225, PMID:24487413, PMID:24501221, PMID:24573247, PMID:24641375, PMID:24651012, PMID:24677579, PMID:24728327, PMID:24810334, PMID:24868540, PMID:25157968, PMID:25525159, PMID:25527155, PMID:25584008, PMID:25741868, PMID:25787918, PMID:25952993, PMID:26086041, PMID:26230955, PMID:26467025, PMID:26585234, PMID:26619011, PMID:26681312, PMID:26822237, PMID:26845104, PMID:27153395, PMID:27276561, PMID:27374712, PMID:27463065, PMID:27493922, PMID:27516001, PMID:27680515, PMID:27683180, PMID:27895058, PMID:27959731, PMID:28125078, PMID:28349240, PMID:28369373, PMID:28453743, PMID:28492532, PMID:28772286, PMID:28861920, PMID:29478780, PMID:29489754, PMID:29945567, PMID:30076369, PMID:30224644, PMID:30287823, PMID:30327374, PMID:30374176, PMID:30883245, PMID:31016814, PMID:31159747 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
G Tyms thymidylate synthase ISO human tumor in mouse model RGD PMID:17848948 RGD:5133430 NCBI chr 5:30,038,546...30,073,645
Ensembl chr 5:30,058,202...30,073,617
JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 ISO mRNA:increased expression:colonic mucosa (human) RGD PMID:8541345 RGD:11352739 NCBI chr 8:70,508,263...70,510,417
Ensembl chr 8:70,508,263...70,510,801
Ensembl chr 4:70,508,263...70,510,801
JBrowse link
G Vegfa vascular endothelial growth factor A treatment ISO RGD PMID:18657413 RGD:15003195 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link
colon adenocarcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa7 annexin A7 ISO protein:decreased expression:colon RGD PMID:17708571 RGD:2292654 NCBI chr14:20,455,261...20,480,133
Ensembl chr14:20,455,260...20,480,133
JBrowse link
G Apc APC, WNT signaling pathway regulator ISO associated with Adenomatous Polyposis Coli;DNA:point mutation:CDS:p.K1137X (3409A>T) (rat)
ClinVar Annotator: match by term: Adenocarcinoma of the colon
ClinVar PMID:24033266, PMID:24728327, PMID:25741868, PMID:27978560, PMID:28492532, PMID:17360473 RGD:1601201 NCBI chr18:34,220,297...34,322,190
Ensembl chr18:34,220,924...34,322,552
JBrowse link
G Bax BCL2-associated X protein susceptibility ISO DNA:frameshift mutation: ; RGD PMID:9020077 RGD:734633 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) treatment IDA RGD PMID:10830715 RGD:10450245 NCBI chr11:54,247,270...54,249,899
Ensembl chr11:54,247,271...54,249,667
JBrowse link
G Ctnnb1 catenin (cadherin associated protein), beta 1 ISO DNA:mutation RGD PMID:16886601 RGD:1599637 NCBI chr 9:120,933,400...120,960,507
Ensembl chr 9:120,929,216...120,960,507
JBrowse link
G Daxx Fas death domain-associated protein ISO protein:decreased expression:colon: RGD PMID:16569639 RGD:9587838 NCBI chr17:33,909,404...33,915,590
Ensembl chr17:33,909,414...33,915,590
JBrowse link
G Fech ferrochelatase ISO mRNA:decreased expression:colon RGD PMID:28075030 RGD:14700888 NCBI chr18:64,456,542...64,489,098
Ensembl chr18:64,452,914...64,490,251
JBrowse link
G Hmgb1 high mobility group box 1 ISO RGD PMID:20616616 RGD:10402080 NCBI chr 5:149,046,702...149,053,057
Ensembl chr 5:149,046,702...149,184,489
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 ISO RGD PMID:24691442 RGD:13210775 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 ISO RGD PMID:24691442 RGD:13210775 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase ISO mRNA:decreased expression:colon (rat) RGD PMID:16886601 RGD:1599637 NCBI chr 7:136,894,463...137,128,193
Ensembl chr 7:136,894,614...137,130,266
JBrowse link
G Mir155 microRNA 155 treatment ISO RGD PMID:29535520 RGD:21409754 NCBI chr16:84,714,140...84,714,204
Ensembl chr16:84,714,140...84,714,204
JBrowse link
G Msh2 mutS homolog 2 ISO ClinVar Annotator: match by term: Adenocarcinoma of the colon ClinVar PMID:8261515, PMID:10978353, PMID:14580774, PMID:15365996, PMID:15655560, PMID:16614121, PMID:17374836, PMID:18325052, PMID:18561205, PMID:22977643, PMID:24033266, PMID:25741868, PMID:28492532, PMID:30311386 NCBI chr17:87,672,532...87,723,713
Ensembl chr17:87,672,330...87,723,713
JBrowse link
G Msh6 mutS homolog 6 ISO ClinVar Annotator: match by term: Adenocarcinoma of the colon ClinVar PMID:25741868 NCBI chr17:87,975,050...87,990,892
Ensembl chr17:87,975,062...87,990,892
JBrowse link
G Pcsk5 proprotein convertase subtilisin/kexin type 5 ISO mRNA:decreased expression:colon: RGD PMID:19737405 RGD:11556207 NCBI chr19:17,432,314...17,837,712
Ensembl chr19:17,432,319...17,837,632
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO DNA:mutation RGD PMID:17575153 RGD:5685670 NCBI chr 3:32,397,065...32,466,112
Ensembl chr 3:32,397,671...32,468,486
JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 treatment ISO RGD PMID:24632606 RGD:13432053 NCBI chr 4:116,221,400...116,303,056
Ensembl chr 4:116,221,618...116,303,056
Ensembl chr 4:116,221,618...116,303,056
JBrowse link
G Ppm1d protein phosphatase 1D magnesium-dependent, delta isoform ISO ClinVar Annotator: match by term: Adenocarcinoma of the colon ClinVar PMID:30311386 NCBI chr11:85,311,254...85,347,071
Ensembl chr11:85,311,244...85,347,066
JBrowse link
G Rac1 Rac family small GTPase 1 treatment ISO mRNA:alternative form RGD PMID:10597294, PMID:19561401 RGD:13432049, RGD:13432051 NCBI chr 5:143,505,481...143,528,031
Ensembl chr 5:143,503,634...143,528,036
JBrowse link
G Rad54l RAD54 like (S. cerevisiae) ISO ClinVar Annotator: match by synonym: Colonic adenocarcinoma ClinVar PMID:10362365 NCBI chr 4:116,094,261...116,123,700
Ensembl chr 4:116,094,264...116,123,690
JBrowse link
G Srsf4 serine and arginine-rich splicing factor 4 ISO mRNA:decreased expression:colon mucosa (human) RGD PMID:9865741 RGD:11039405 NCBI chr 4:131,873,530...131,901,725
Ensembl chr 4:131,873,617...131,901,706
JBrowse link
G Srsf5 serine and arginine-rich splicing factor 5 ISO mRNA:decreased expression:colon mucosa (human) RGD PMID:9865741 RGD:11039405 NCBI chr12:80,945,495...80,950,507
Ensembl chr12:80,945,504...80,950,507
JBrowse link
G Srsf6 serine and arginine-rich splicing factor 6 ISO mRNA:decreased expression:colon mucosa (human) RGD PMID:9865741 RGD:11039405 NCBI chr 2:162,931,508...162,937,121
Ensembl chr 2:162,931,528...162,937,121
JBrowse link
G Tert telomerase reverse transcriptase treatment IMP RGD PMID:19903903 RGD:11038656 NCBI chr13:73,626,911...73,649,843
Ensembl chr13:73,626,911...73,649,843
JBrowse link
G Tgfb1 transforming growth factor, beta 1 disease_progression ISO RGD PMID:9019169 RGD:13432089 NCBI chr 7:25,687,002...25,705,077
Ensembl chr 7:25,687,002...25,705,077
JBrowse link
G Vegfc vascular endothelial growth factor C ISO mRNA:increased expression:colon RGD PMID:18424890 RGD:2315488 NCBI chr 8:54,077,532...54,186,454
Ensembl chr 8:54,077,606...54,187,096
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13334
    disease of cellular proliferation 5752
      cancer 4190
        cell type cancer 3113
          carcinoma 2095
            colon carcinoma 75
              adenosquamous colon carcinoma 0
              colon adenocarcinoma + 26
              colon carcinoma in situ 0
              colon small cell carcinoma 0
              colon squamous cell carcinoma 0
              medullary colon carcinoma 0
Path 2
Term Annotations click to browse term
  disease 13334
    disease of anatomical entity 12815
      gastrointestinal system disease 4354
        Gastrointestinal Diseases 2534
          Gastrointestinal Neoplasms 1733
            Intestinal Neoplasms 670
              intestinal cancer 246
                large intestine cancer 242
                  colorectal cancer 242
                    colon cancer 130
                      colon carcinoma 75
                        adenosquamous colon carcinoma 0
                        colon adenocarcinoma + 26
                        colon carcinoma in situ 0
                        colon small cell carcinoma 0
                        colon squamous cell carcinoma 0
                        medullary colon carcinoma 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.