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ONTOLOGY REPORT - ANNOTATIONS


Term:arthus reaction
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Accession:DOID:1556 term browser browse the term
Definition:A dermal inflammatory reaction produced under conditions of antibody excess, when a second injection of antigen produces intravascular antigen-antibody complexes which bind complement, causing cell clumping, endothelial damage, and vascular necrosis.
Synonyms:exact_synonym: arthus phenomenon;   arthus type urticaria
 primary_id: MESH:D001183
 alt_id: RDO:0004915
 xref: NCI:C34400
For additional species annotation, visit the Alliance of Genome Resources.


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arthus reaction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Btk Bruton tyrosine kinase JBrowse link X 105,360,922 105,390,580 RGD:11040701
G Cfd complement factor D JBrowse link 7 12,634,216 12,635,939 RGD:1624328
G Cx3cr1 C-X3-C motif chemokine receptor 1 JBrowse link 8 128,740,756 128,754,514 RGD:9068463
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:9588604

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15036
    disease of anatomical entity 14171
      immune system disease 2448
        hypersensitivity reaction disease 1483
          hypersensitivity reaction type III disease 26
            arthus reaction 4
Path 2
Term Annotations click to browse term
  disease 15036
    disease of anatomical entity 14171
      Immune & Inflammatory Diseases 3022
        immune system disease 2448
          hypersensitivity reaction disease 1483
            allergic hypersensitivity disease 550
              hypersensitivity reaction type III disease 26
                arthus reaction 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.