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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:rheumatic disease
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Accession:DOID:1575 term browser browse the term
Definition:Disorders of connective tissue, especially the joints and related structures, characterized by inflammation, degeneration, or metabolic derangement.
Synonyms:exact_synonym: rheumatic diseases;   rheumatism
 primary_id: MESH:D012216
For additional species annotation, visit the Alliance of Genome Resources.


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adult-onset Still's disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HGF hepatocyte growth factor ISO protein:increased expression:serum: RGD PMID:24387171 RGD:8548659 NCBI chr 7:73,667,618...73,738,960
Ensembl chr 7:87,327,798...87,397,811
JBrowse link
G VEGFA vascular endothelial growth factor A ISO protein:increased expression:serum: RGD PMID:24387171 RGD:8548659 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353
JBrowse link
Beukes hip dysplasia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4H4orf47 chromosome 4 C4orf47 homolog ISO ClinVar Annotator: match by term: Hip dysplasia, beukes type ClinVar PMID:2389793, PMID:21228277, PMID:26428751 NCBI chr 4:177,589,308...177,612,834
Ensembl chr 4:189,805,849...189,828,919
JBrowse link
G UFSP2 UFM1 specific peptidase 2 ISO OMIM NCBI chr 4:177,562,642...177,589,312
Ensembl chr 4:189,779,242...189,805,572
JBrowse link
CREST syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CENPC centromere protein C ISO associated with Anticentromere antibody positivity RGD PMID:25220385 RGD:27372886 NCBI chr 4:56,503,353...56,615,246
Ensembl chr 4:62,895,561...62,968,383
JBrowse link
G FBN1 fibrillin 1 ISO RGD PMID:10395706 RGD:12910471 NCBI chr15:27,358,780...27,593,539
Ensembl chr15:45,682,450...45,918,111
JBrowse link
diffuse scleroderma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing severity ISO protein:decreased expression:serum RGD PMID:21615510 RGD:8694418 NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885
JBrowse link
G AGT angiotensinogen ISO protein:increased expression:serum RGD PMID:14730619 RGD:8548886 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044
JBrowse link
G BANK1 B cell scaffold protein with ankyrin repeats 1 susceptibility ISO DNA:SNPs: :rs10516487,rs17266594,rs3733197(human) RGD PMID:19815934 RGD:9684975 NCBI chr 4:94,216,751...94,507,965
Ensembl chr 4:104,813,791...105,171,527
JBrowse link
G CAV1 caveolin 1 no_association
susceptibility
ISO DNA:SNPs:enhancer, intron:multiple
DNA:SNPs:intron, 3' utr: (rs729949, rs3815412, rs9920) (human)
RGD PMID:22402147 RGD:8661768 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655
JBrowse link
G CXCL5 C-X-C motif chemokine ligand 5 ISO RGD PMID:18432520 RGD:5135258 NCBI chr 4:50,192,665...50,195,642
Ensembl chr 4:56,024,848...56,027,989
JBrowse link
G FCGR2A Fc fragment of IgG receptor IIa ISO RGD PMID:8254199 RGD:5147984 NCBI chr 1:136,892,311...136,906,450 JBrowse link
G IL10 interleukin 10 ISO protein:increased expression:serum RGD PMID:9034992 RGD:5684371 NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371
JBrowse link
G IL13 interleukin 13 ISO DNA:SNPs:5' utr, enhancer: (rs1800925, rs2243204) (human) RGD PMID:16832637 RGD:5684369 NCBI chr 5:128,073,863...128,078,453
Ensembl chr 5:134,235,788...134,240,548
JBrowse link
G IL6 interleukin 6 treatment ISO RGD PMID:20338043 RGD:12792275 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 susceptibility ISO DNA:missense mutation:cds:p.F196S (rs1059702) (human) RGD PMID:21898345 RGD:7495782 NCBI chr  X:143,560,802...143,570,185
Ensembl chr  X:153,446,827...153,460,602
JBrowse link
G KDR kinase insert domain receptor ISO protein:increased expression:serum: RGD PMID:19886888 RGD:8551850 NCBI chr 4:68,813,894...68,861,018
Ensembl chr 4:75,377,375...75,427,109
JBrowse link
G STAT4 signal transducer and activator of transcription 4 no_association
susceptibility
ISO DNA:SNP:intron: (rs3821236) (human)
DNA:SNP:intron: (rs7574865) (human)
DNA:SNP:introns: (rs7574865, rs10168266) (human)
RGD PMID:19286670, PMID:23755762 RGD:8661701, RGD:8661714 NCBI chr2B:78,331,402...78,549,231
Ensembl chr2B:196,247,881...196,366,011
JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member susceptibility ISO RGD PMID:16112028 RGD:1578361 NCBI chr 6:32,414,665...32,423,488
Ensembl chr 6:33,530,171...33,538,978
JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member susceptibility ISO RGD PMID:16112028 RGD:1578361 NCBI chr 6:32,394,586...32,408,297
Ensembl chr 6:33,507,332...33,523,750
JBrowse link
G TLR2 toll like receptor 2 disease_progression ISO DNA:polymorphism:cds:p.P631H(rs5743704)(human) RGD PMID:21905008 RGD:8553044 NCBI chr 4:146,024,653...146,091,388
Ensembl chr 4:157,866,977...157,869,331
JBrowse link
G WRN WRN RecQ like helicase ISO RGD PMID:16906373 RGD:10042980 NCBI chr 8:30,353,643...30,492,978
Ensembl chr 8:27,541,145...27,679,855
JBrowse link
Digital Arthropathy-Brachydactyly, Familial term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRPV4 transient receptor potential cation channel subfamily V member 4 ISO OMIM NCBI chr12:107,359,005...107,409,359
Ensembl chr12:110,754,238...110,786,182
JBrowse link
erythema nodosum term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 ISO associated with Leprosy RGD PMID:2783924 RGD:7421527 NCBI chr19:5,708,211...5,753,178
Ensembl chr19:6,629,287...6,674,699
JBrowse link
G CFB complement factor B ISO associated with Leprosy RGD PMID:2783924 RGD:7421527 NCBI chr 6:31,606,716...31,612,782 JBrowse link
G GSTM1 glutathione S-transferase mu 1 susceptibility ISO associated with Behcet Syndrome;DNA:deletion:: (human) RGD PMID:22766250 RGD:7794848 Ensembl chr 1:127,979,238...128,010,411 JBrowse link
G LOC100982859 patr class I histocompatibility antigen, B-2 alpha chain ISO associated with Inflammatory Bowel Diseases; DNA:polymorphisms:cds:multiple (human) RGD PMID:12198697 RGD:7364926 NCBI chr 6:31,106,562...31,109,933
Ensembl chr 6:31,997,381...32,000,067
JBrowse link
G LTA lymphotoxin alpha ISO associated with Sarcoidosis;DNA:polymorphism:intron RGD PMID:19225544 RGD:8548773 NCBI chr 6:31,233,411...31,235,409
Ensembl chr 6:32,123,353...32,125,375
JBrowse link
G TNF tumor necrosis factor susceptibility ISO associated with Inflammatory Bowel Diseases;DNA:polymorphisms: :-1031T>C(human) RGD PMID:12198697 RGD:7364926 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
G VDR vitamin D receptor susceptibility ISO associated with Behcet Syndrome;DNA:polymorphism: : rs7975232(human) RGD PMID:24880677 RGD:13217417 NCBI chr12:40,828,413...40,891,700
Ensembl chr12:41,702,742...41,766,192
JBrowse link
Familial Osteochondritis Dissecans term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAN aggrecan ISO OMIM NCBI chr15:67,492,494...67,563,265
Ensembl chr15:86,733,853...86,771,420
JBrowse link
fibromyalgia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAT catalase ISO protein:decreased activity:mononuclear cell: RGD PMID:22532869 RGD:9479066 NCBI chr11:34,413,253...34,446,831
Ensembl chr11:34,289,603...34,323,160
JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO protein:decreased expression:plasma RGD PMID:19924498 RGD:14995946 NCBI chr17:22,528,154...22,530,091
Ensembl chr17:22,820,890...22,823,384
JBrowse link
G COMT catechol-O-methyltransferase severity ISO DNA:polymorphism:cds:p.V158M(human) RGD PMID:24762091 RGD:13450944 NCBI chr22:2,704,015...2,731,326
Ensembl chr22:18,375,434...18,402,387
JBrowse link
G LOC100991079 interleukin-1 receptor antagonist protein severity ISO protein:increased expression:serum (human) RGD PMID:10341365 RGD:8549787 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839
JBrowse link
Hand Osteoarthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ESR1 estrogen receptor 1 no_association ISO DNA:SNPs:exons: (rs2077647, rs1801132) (human) RGD PMID:19884274 RGD:10045830 NCBI chr 6:149,507,599...149,918,523
Ensembl chr 6:154,317,002...154,631,551
JBrowse link
G ESR2 estrogen receptor 2 no_association ISO DNA:SNPs:introns: (rs1256034, rs1256059, rs944460) (human) RGD PMID:19884274 RGD:10045830 NCBI chr14:44,807,875...44,919,780
Ensembl chr14:63,064,402...63,131,303
JBrowse link
G IL4 interleukin 4 no_association ISO DNA:SNPs:promoter, 5' utr, intron:multiple RGD PMID:20219689 RGD:10402786 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
G IL4R interleukin 4 receptor no_association ISO DNA:SNPs:promoter, exons:multiple RGD PMID:20219689 RGD:10402786 Ensembl chr16:27,642,702...27,737,445 JBrowse link
G MATN3 matrilin 3 ISO ClinVar Annotator: match by term: HAND OSTEOARTHRITIS ClinVar PMID:12736871 NCBI chr2A:19,979,188...20,000,733
Ensembl chr2A:20,095,710...20,116,015
JBrowse link
juvenile rheumatoid arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP3 acid phosphatase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:129,392,396...129,465,962
Ensembl chr 3:136,713,816...136,764,655
JBrowse link
G ACRBP acrosin binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:6,768,971...6,778,613
Ensembl chr12:6,685,963...6,695,344
JBrowse link
G ADCY7 adenylate cyclase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr16:30,507,836...30,581,068
Ensembl chr16:49,410,143...49,462,278
JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:7,026,839...7,041,598
Ensembl chr17:7,014,591...7,029,602
JBrowse link
G ANKRD9 ankyrin repeat domain 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:83,122,024...83,128,173 JBrowse link
G AOPEP aminopeptidase O (putative) ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:65,825,138...66,188,001
Ensembl chr 9:93,986,951...94,311,201
JBrowse link
G APOBEC3A apolipoprotein B mRNA editing enzyme catalytic subunit 3A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr22:19,866,522...19,872,836 JBrowse link
G AQP9 aquaporin 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:37,107,061...37,154,887
Ensembl chr15:55,418,767...55,466,541
JBrowse link
G AREG amphiregulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:49,737,191...49,747,013 JBrowse link
G ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:126,688,608...127,080,662
Ensembl chr 8:129,418,796...130,021,261
JBrowse link
G AVL9 AVL9 cell migration associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:33,104,760...33,194,941 JBrowse link
G B4GALT5 beta-1,4-galactosyltransferase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr20:45,977,801...46,058,429
Ensembl chr20:47,041,469...47,123,214
JBrowse link
G BEND2 BEN domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr  X:10,786,031...10,844,265
Ensembl chr  X:18,151,097...18,208,838
JBrowse link
G BTG1 BTG anti-proliferation factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:89,678,431...89,681,177
Ensembl chr12:92,992,584...92,994,038
JBrowse link
G BTG3 BTG anti-proliferation factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr21:4,327,813...4,347,053
Ensembl chr21:17,693,067...17,712,280
JBrowse link
G C2BH2orf88 chromosome 2B C2orf88 homolog ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr2B:77,446,455...77,509,809
Ensembl chr2B:195,424,996...195,425,283
JBrowse link
G C8B complement C8 beta chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:7980680 NCBI chr 1:56,213,618...56,250,488
Ensembl chr 1:57,923,720...57,960,674
JBrowse link
G C9orf72 C9orf72-SMCR8 complex subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:27,395,054...27,422,282
Ensembl chr 9:28,001,813...28,022,066
JBrowse link
G CALD1 caldesmon 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:126,743,466...126,935,412
Ensembl chr 7:139,337,692...139,440,643
JBrowse link
G CAMSAP1 calmodulin regulated spectrin associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:106,881,023...106,979,501
Ensembl chr 9:135,866,980...135,944,911
JBrowse link
G CCR5 C-C motif chemokine receptor 5 no_association ISO DNA:polymorphisms: :multiple (human)
DNA:frameshift mutation:cds:p.S185_T195del rs333 (human)
RGD PMID:16775617, PMID:17565662 RGD:1626283, RGD:1626284 NCBI chr 3:46,273,096...46,278,471
Ensembl chr 3:47,380,321...47,381,379
JBrowse link
G CD14 CD14 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:135,996,265...135,997,909
Ensembl chr 5:142,113,082...142,118,966
JBrowse link
G CD83 CD83 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:13,961,342...13,980,686
Ensembl chr 6:14,330,752...14,349,946
JBrowse link
G CD8B CD8b molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr2A:86,863,320...86,909,989 JBrowse link
G CIITA class II major histocompatibility complex transactivator no_association
susceptibility
ISO DNA:polymorphism:promoter:rs3087456, no association in a German cohort
DNA:polymorphism:exon:1614G>C (human)
RGD PMID:16426246, PMID:17661914 RGD:5491187, RGD:5491189 NCBI chr16:9,819,440...9,885,379
Ensembl chr16:11,041,434...11,090,485
JBrowse link
G CLU clusterin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:26,867,973...26,884,838
Ensembl chr 8:24,070,053...24,083,523
JBrowse link
G CMTM2 CKLF like MARVEL transmembrane domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr16:46,897,655...46,906,760
Ensembl chr16:65,999,285...66,007,739
JBrowse link
G CREM cAMP responsive element modulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:35,247,426...35,335,545
Ensembl chr10:35,825,218...35,912,432
JBrowse link
G CRP C-reactive protein ISO protein:increased expression:serum RGD PMID:22885951 RGD:6906884 NCBI chr 1:135,062,102...135,064,402 JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr2B:91,054,917...91,106,234
Ensembl chr2B:209,239,417...209,244,498
JBrowse link
G CTTN cortactin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:65,500,074...65,539,158 JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:50,325,248...50,327,165
Ensembl chr 4:56,153,899...56,159,474
JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr2B:105,387,198...105,400,533
Ensembl chr2B:223,997,066...223,998,148
JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504, PMID:26387944 NCBI chr2B:23,744,271...23,748,106
Ensembl chr2B:140,181,829...140,189,647
JBrowse link
G DAPK1 death associated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:58,628,872...58,836,205
Ensembl chr 9:86,681,953...86,887,958
JBrowse link
G DDIT3 DNA damage inducible transcript 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:31,406,332...31,410,293
Ensembl chr12:31,664,743...31,668,701
JBrowse link
G DUSP1 dual specificity phosphatase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:168,121,536...168,124,671
Ensembl chr 5:175,032,803...175,035,960
JBrowse link
G DUSP2 dual specificity phosphatase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr2A:103,169,874...103,172,158 JBrowse link
G DUSP4 dual specificity phosphatase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:28,623,777...28,641,432
Ensembl chr 8:25,819,989...25,834,332
JBrowse link
G DYSF dysferlin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr2A:71,495,573...71,730,073
Ensembl chr2A:72,994,888...73,228,846
JBrowse link
G EGF epidermal growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:102,410,724...102,509,691
Ensembl chr 4:112,977,565...113,076,460
JBrowse link
G EGR1 early growth response 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:133,845,305...133,849,291
Ensembl chr 5:139,975,635...139,979,260
JBrowse link
G ELF2 E74 like ETS transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:131,420,985...131,540,691
Ensembl chr 4:142,731,593...142,850,778
JBrowse link
G ETNK1 ethanolamine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:63,623,723...63,690,306
Ensembl chr12:66,237,566...66,297,223
JBrowse link
G ETV6 ETS variant transcription factor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:11,675,955...11,920,913
Ensembl chr12:11,844,939...12,179,537
JBrowse link
G FAM20A FAM20A golgi associated secretory pathway pseudokinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:62,474,317...62,537,800
Ensembl chr17:67,864,331...67,927,128
JBrowse link
G FAXDC2 fatty acid hydroxylase domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:150,222,289...150,255,055
Ensembl chr 5:156,217,594...156,249,567
JBrowse link
G FCGR1A Fc fragment of IgG receptor Ia ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:125,127,073...125,136,911
Ensembl chr 1:128,805,484...128,814,220
JBrowse link
G FCHSD2 FCH and double SH3 domains 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:67,915,796...68,219,482 JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:55,832,570...55,835,984
Ensembl chr14:74,676,316...74,679,766
JBrowse link
G FOSB FosB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr19:42,416,781...42,424,003
Ensembl chr19:51,013,350...51,020,570
JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr2A:28,392,328...28,416,838
Ensembl chr2A:28,485,613...28,498,397
JBrowse link
G FOXP1 forkhead box P1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:70,893,933...71,523,892
Ensembl chr 3:72,258,456...72,498,173
JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:66,925,063...66,928,222
Ensembl chr 1:68,880,912...68,884,188
JBrowse link
G GMPR guanosine monophosphate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:16,094,994...16,151,499
Ensembl chr 6:16,460,651...16,515,796
JBrowse link
G GNG11 G protein subunit gamma 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:85,870,321...85,875,309
Ensembl chr 7:99,461,797...99,466,632
JBrowse link
G GP1BB glycoprotein Ib platelet subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr22:2,485,350...2,486,688 JBrowse link
G HBEGF heparin binding EGF like growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:135,699,553...135,713,366
Ensembl chr 5:141,816,402...141,830,531
JBrowse link
G HERPUD2 HERPUD family member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:36,259,315...36,321,705
Ensembl chr 7:36,494,153...36,556,481
JBrowse link
G HFE homeostatic iron regulator ISO DNA:missense mutation:cds:p.C282Y (human) RGD PMID:16047841 RGD:8694357 NCBI chr 6:25,921,663...25,930,852
Ensembl chr 6:26,580,358...26,588,591
JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 ISO protein:increased expression:serum,synovial fluid: RGD PMID:8255671 RGD:12910480 NCBI chr2B:84,729,615...84,743,352
Ensembl chr2B:202,623,497...202,636,959
JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974
JBrowse link
G IL1A interleukin 1 alpha ISO DNA:SNP:promoter:-889C>T (human) RGD PMID:8162643 RGD:7794716 NCBI chr2A:89,273,482...89,284,421
Ensembl chr2A:113,784,854...113,795,801
JBrowse link
G IL2 interleukin 2 ISO protein:increased expression:mononuclear cell RGD PMID:21859687 RGD:5147870 NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984
JBrowse link
G IL6 interleukin 6 ISO protein:increased expression:serum: RGD PMID:9489833 RGD:7829742 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G ITGA2B integrin subunit alpha 2b ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:13,009,514...13,027,289
Ensembl chr17:13,176,843...13,193,269
JBrowse link
G ITGB5 integrin subunit beta 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:121,863,676...122,013,438
Ensembl chr 3:128,762,200...128,877,172
JBrowse link
G JMJD1C jumonji domain containing 1C ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:59,674,227...60,028,763
Ensembl chr10:61,999,571...62,295,332
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:58,042,794...58,045,536 JBrowse link
G KAT6B lysine acetyltransferase 6B ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:71,354,585...71,561,572
Ensembl chr10:74,035,496...74,223,975
JBrowse link
G KCNJ15 potassium inwardly rectifying channel subfamily J member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr21:24,615,779...24,668,267
Ensembl chr21:38,010,261...38,011,388
JBrowse link
G KLF4 Kruppel like factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:78,634,545...78,639,447
Ensembl chr 9:106,820,954...106,825,797
JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:61,062,689...61,108,524
Ensembl chr12:63,679,293...63,724,335
JBrowse link
G LACC1 laccase domain containing 1 ISO OMIM NCBI chr13:25,047,306...25,063,644
Ensembl chr 3:198,998,153...199,012,230
JBrowse link
G LILRA5 leukocyte immunoglobulin like receptor A5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr19:51,265,665...51,272,519
Ensembl chr19:60,106,656...60,112,709
JBrowse link
G LOC100972994 HLA class II histocompatibility antigen, DQ beta 1 chain ISO DNA:polymorphism (human) RGD PMID:10457895 RGD:5147863 NCBI chr 6:32,237,395...32,244,201
Ensembl chr 6:33,353,599...33,360,272
JBrowse link
G LOC100980195 histone H2A type 1-B ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:26,051,779...26,052,699 JBrowse link
G LOC100985450 histone H2B type 1-C/E/F/G/I ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:26,051,127...26,051,730
Ensembl chr 6:26,679,372...26,679,752
Ensembl chr 6:26,679,372...26,679,752
Ensembl chr 6:26,679,372...26,679,752
Ensembl chr 6:26,679,372...26,679,752
JBrowse link
G LOC100991079 interleukin-1 receptor antagonist protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839
JBrowse link
G LPP LIM domain containing preferred translocation partner in lipoma ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:185,179,432...185,916,477
Ensembl chr 3:193,991,530...194,462,641
JBrowse link
G MAD1L1 mitotic arrest deficient 1 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:2,070,299...2,502,471
Ensembl chr 7:2,187,104...2,601,328
JBrowse link
G MAFF MAF bZIP transcription factor F ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr22:19,114,929...19,129,901 JBrowse link
G MAML2 mastermind like transcriptional coactivator 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:90,982,013...91,350,289
Ensembl chr11:94,511,873...94,873,977
JBrowse link
G MAP2 microtubule associated protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr2B:96,681,268...96,991,650
Ensembl chr2B:215,314,857...215,391,728
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335
JBrowse link
G MBL2 mannose binding lectin 2 ISO RGD PMID:18334024 RGD:12910845 NCBI chr10:49,401,364...49,409,328
Ensembl chr10:51,527,758...51,543,432
JBrowse link
G MEX3C mex-3 RNA binding family member C ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr18:44,546,129...44,569,580 JBrowse link
G MS4A4A membrane spanning 4-domains A4A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:55,512,315...55,540,758
Ensembl chr11:58,955,095...58,983,570
JBrowse link
G MSN moesin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr  X:54,785,309...54,859,364
Ensembl chr  X:64,781,550...64,933,292
JBrowse link
G MTSS1 MTSS I-BAR domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:121,235,545...121,413,037
Ensembl chr 8:123,987,577...124,032,339
JBrowse link
G MYZAP myocardial zonula adherens protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:36,560,355...36,653,881 JBrowse link
G NDEL1 nudE neurodevelopment protein 1 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:43,186,255...43,218,436 JBrowse link
G NR4A2 nuclear receptor subfamily 4 group A member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr2B:43,584,835...43,593,118
Ensembl chr2B:160,826,091...160,837,162
JBrowse link
G NR4A3 nuclear receptor subfamily 4 group A member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:70,907,056...70,950,221 JBrowse link
G NRG1 neuregulin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:30,954,852...32,084,411
Ensembl chr 8:29,050,222...29,263,977
JBrowse link
G OLR1 oxidized low density lipoprotein receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:10,196,712...10,210,432
Ensembl chr12:10,445,202...10,461,071
JBrowse link
G OSM oncostatin M ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr22:11,298,965...11,303,009
Ensembl chr22:29,101,085...29,105,081
JBrowse link
G PACSIN2 protein kinase C and casein kinase substrate in neurons 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr22:23,757,565...23,900,837
Ensembl chr22:41,908,922...41,999,692
JBrowse link
G PCYT1B phosphate cytidylyltransferase 1, choline, beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr  X:17,155,065...17,269,909
Ensembl chr  X:24,522,460...24,636,942
JBrowse link
G PER1 period circadian regulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:43,502,080...43,518,098
Ensembl chr17:48,234,360...48,250,391
JBrowse link
G PGM5 phosphoglucomutase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:56,262,870...56,412,833 JBrowse link
G PLAUR plasminogen activator, urokinase receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr19:40,588,100...40,616,479
Ensembl chr19:49,197,341...49,222,561
Ensembl chr19:49,197,341...49,222,561
JBrowse link
G PLK2 polo like kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:55,543,828...55,550,116
Ensembl chr 5:57,177,836...57,184,793
JBrowse link
G PLOD2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:143,091,833...143,181,831
Ensembl chr 3:150,675,424...150,764,939
JBrowse link
G PROS1 protein S ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:90,934,641...91,039,059
Ensembl chr 3:97,615,734...97,718,756
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 ISO DNA: snp : cds : rs2476601 RGD PMID:15934099 RGD:6484550 NCBI chr 1:88,685,736...88,743,164
Ensembl chr 1:123,734,511...123,790,830
JBrowse link
G R3HDM2 R3H domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:31,494,789...31,672,343
Ensembl chr12:31,868,368...31,923,910
JBrowse link
G RASGEF1B RasGEF domain family member 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:42,153,818...42,771,749
Ensembl chr 4:48,004,253...48,620,978
JBrowse link
G RBM47 RNA binding motif protein 47 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:34,744,484...34,951,402
Ensembl chr 4:40,597,366...40,640,599
JBrowse link
G RERE arginine-glutamic acid dipeptide repeats ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:7,111,594...7,576,667
Ensembl chr 1:8,351,367...8,648,973
JBrowse link
G RHOBTB1 Rho related BTB domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:57,410,347...57,541,038
Ensembl chr10:59,740,662...59,815,536
JBrowse link
G RNF103 ring finger protein 103 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr2A:86,659,672...86,680,154 JBrowse link
G SELP selectin P severity ISO protein:increased expression:plasma RGD PMID:21124648 RGD:6219006 NCBI chr 1:145,071,094...145,112,851
Ensembl chr 1:148,793,677...148,834,701
JBrowse link
G SH2D2A SH2 domain containing 2A ISO DNA:polymorphism:promoter RGD PMID:15129233 RGD:2298870 NCBI chr 1:132,149,450...132,160,280
Ensembl chr 1:135,972,824...135,981,754
JBrowse link
G SH3BGRL2 SH3 domain binding glutamate rich protein like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:77,303,334...77,584,938
Ensembl chr 6:80,782,103...80,850,087
JBrowse link
G SIK1 salt inducible kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr21:29,675,040...29,689,408 JBrowse link
G SIPA1L1 signal induced proliferation associated 1 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:51,909,444...52,328,719
Ensembl chr14:71,038,600...71,192,916
JBrowse link
G SLC11A1 solute carrier family 11 member 1 ISO DNA:repeat:promoter (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:10857800, PMID:16597321 RGD:5684977 NCBI chr2B:105,640,613...105,655,524
Ensembl chr2B:224,238,284...224,252,941
JBrowse link
G SLC22A16 solute carrier family 22 member 16 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:108,232,950...108,332,469
Ensembl chr 6:112,302,265...112,354,829
JBrowse link
G SLC26A2 solute carrier family 26 member 2 susceptibility ISO DNA:SNPs: : RGD PMID:17393463 RGD:13208931 NCBI chr 5:145,385,433...145,412,180
Ensembl chr 5:151,391,842...151,412,676
JBrowse link
G SMAD3 SMAD family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:46,013,764...46,143,126
Ensembl chr15:64,284,949...64,414,185
JBrowse link
G STAB1 stabilin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:52,437,378...52,466,143
Ensembl chr 3:53,665,386...53,694,139
JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:14,928,689...15,003,644
Ensembl chr17:15,152,358...15,227,067
JBrowse link
G STIM1 stromal interaction molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:3,726,501...3,954,951
Ensembl chr11:3,840,513...4,065,224
JBrowse link
G TCF7L2 transcription factor 7 like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:109,541,524...109,759,499
Ensembl chr10:112,978,167...113,192,281
JBrowse link
G TFDP1 transcription factor Dp-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:94,730,343...94,789,328
Ensembl chr13:113,789,280...113,840,825
JBrowse link
G TFPI tissue factor pathway inhibitor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr2B:74,744,154...74,834,338
Ensembl chr2B:192,541,881...192,581,384
JBrowse link
G THBD thrombomodulin ISO protein:increased expression:serum RGD PMID:15209962 RGD:5685023 NCBI chr20:22,992,341...22,996,415
Ensembl chr20:23,345,917...23,347,812
JBrowse link
G THBS1 thrombospondin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:18,521,802...18,538,172
Ensembl chr15:36,776,756...36,793,170
JBrowse link
G TNFAIP6 TNF alpha induced protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr2B:38,669,652...38,692,037
Ensembl chr2B:155,933,842...155,956,382
JBrowse link
G TNFAIP8 TNF alpha induced protein 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:114,657,140...114,784,819
Ensembl chr 5:120,442,500...120,569,877
JBrowse link
G TNFRSF10C TNF receptor superfamily member 10c ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:22,352,777...22,368,737
Ensembl chr 8:19,292,020...19,307,719
JBrowse link
G TNIK TRAF2 and NCK interacting kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:168,067,839...168,466,290
Ensembl chr 3:176,255,547...176,650,795
JBrowse link
G TREML1 triggering receptor expressed on myeloid cells like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:40,726,243...40,731,358
Ensembl chr 6:42,034,988...42,039,695
JBrowse link
G TTLL5 tubulin tyrosine ligase like 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:56,216,214...56,513,718
Ensembl chr14:75,058,897...75,356,494
JBrowse link
G TUBB2A tubulin beta 2A class IIa ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:2,993,653...2,997,570 JBrowse link
G UBE2E1 ubiquitin conjugating enzyme E2 E1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:23,719,632...23,803,302
Ensembl chr 3:24,045,747...24,127,820
JBrowse link
G UBE3C ubiquitin protein ligase E3C ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:148,756,024...148,886,688
Ensembl chr 7:160,474,767...160,580,046
JBrowse link
G UHRF1BP1L UHRF1 binding protein 1 like ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:97,617,019...97,723,669
Ensembl chr12:101,026,575...101,131,811
JBrowse link
G WASF3 WASP family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:7,849,687...7,980,979
Ensembl chr13:26,250,171...26,328,553
JBrowse link
G WWOX WW domain containing oxidoreductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr16:58,689,609...59,800,333
Ensembl chr16:78,125,302...79,231,546
JBrowse link
G ZFAND3 zinc finger AN1-type containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:37,383,659...37,743,202
Ensembl chr 6:38,683,961...38,906,806
JBrowse link
G ZFC3H1 zinc finger C3H1-type containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:69,133,048...69,187,291
Ensembl chr12:71,992,638...72,047,056
JBrowse link
Knee Osteoarthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA2 annexin A2 disease_progression ISO protein:increased expression:chondrocyte: RGD PMID:10903884 RGD:10053727 NCBI chr15:39,322,303...39,371,565
Ensembl chr15:57,625,425...57,674,250
JBrowse link
G ANXA5 annexin A5 disease_progression ISO protein:increased expression:chondrocyte: RGD PMID:10903884 RGD:10053727 NCBI chr 4:113,868,218...113,897,243
Ensembl chr 4:125,006,038...125,034,972
JBrowse link
G AR androgen receptor ISO DNA:repeat:exon:c.172(CAG)8-34 (human) RGD PMID:16098017 RGD:10043199 NCBI chr  X:56,722,828...56,909,004
Ensembl chr  X:66,791,081...66,969,357
JBrowse link
G ASPN asporin severity ISO DNA:repeats:exon:
mRNA:increased expression:cartilage:
RGD PMID:15640800 RGD:9684965 NCBI chr 9:63,579,188...63,605,811
Ensembl chr 9:91,651,629...91,677,969
JBrowse link
G B2M beta-2-microglobulin ISO protein:increased expression:serum RGD PMID:18795399 RGD:6482710 NCBI chr15:23,668,108...23,674,791
Ensembl chr15:41,836,345...41,842,991
JBrowse link
G BAX BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:20131282 RGD:6907382 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO RGD PMID:20131282 RGD:6907382 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein ISO RGD PMID:21387139, PMID:22294259 RGD:6483563, RGD:6483595 NCBI chr 1:131,583,789...131,586,459
Ensembl chr 1:135,413,871...135,416,432
JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO mRNA,protein:increased expression:dorsal root ganglion: RGD PMID:23185004 RGD:8661785 NCBI chr 3:46,255,725...46,263,285
Ensembl chr 3:47,361,124...47,368,312
JBrowse link
G CD36 CD36 molecule disease_progression ISO RGD PMID:19342682, PMID:21765106 RGD:6893494, RGD:6893565 NCBI chr 7:72,566,478...72,643,517
Ensembl chr 7:86,265,114...86,305,865
JBrowse link
G CTNNB1 catenin beta 1 ISO protein:increased expression:cartilage: RGD PMID:22702043 RGD:10395278 NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030
JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 ISO DNA:SNP:intron, 5' utr: (rs1062033) (human) RGD PMID:20417295 RGD:10045662 NCBI chr15:30,152,924...30,282,854
Ensembl chr15:48,486,688...48,521,554
JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 severity ISO mRNA,protein:increased expression:fat pad: RGD PMID:21765106 RGD:6893494 NCBI chr11:70,824,791...70,857,530
Ensembl chr11:74,126,169...74,158,854
JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 ISO RGD PMID:20131282 RGD:6907382 NCBI chr10:48,950,704...48,953,815
Ensembl chr10:51,084,027...51,089,776
JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 ISO RGD PMID:25435813 RGD:13506963 NCBI chr 6:71,342,291...71,346,033 JBrowse link
G EFEMP1 EGF containing fibulin extracellular matrix protein 1 ISO protein:increased expression:serum: RGD PMID:22275171 RGD:10401792 NCBI chr2A:56,017,678...56,076,059
Ensembl chr2A:57,155,000...57,212,500
JBrowse link
G EPAS1 endothelial PAS domain protein 1 no_association ISO DNA:SNP:5' utr: (rs17039192) (human) RGD PMID:20495570, PMID:22247019 RGD:10395367, RGD:10395368 NCBI chr2A:46,403,411...46,492,734
Ensembl chr2A:47,332,308...47,421,560
JBrowse link
G EPO erythropoietin treatment ISO RGD PMID:25422652 RGD:10400892 NCBI chr 7:92,747,671...92,750,886
Ensembl chr 7:106,148,062...106,150,974
JBrowse link
G ESR1 estrogen receptor 1 ISO DNA:SNPs:intron: (rs2234693, rs9340799) (human)
DNA:polymorphisms, haplotype:intron, exon
DNA:SNP:cds:c.1782G>A (rs2228480) (human)
DNA:repeat:promoter:-1174(TA)9-25 (human)
RGD PMID:15380041, PMID:16098017, PMID:20128071, PMID:24772413 RGD:10043199, RGD:10045829, RGD:10045835, RGD:10045840 NCBI chr 6:149,507,599...149,918,523
Ensembl chr 6:154,317,002...154,631,551
JBrowse link
G ESR2 estrogen receptor 2 ISO DNA:repeat:intron:c.1092+3607(CA)13-27 (human) RGD PMID:16098017 RGD:10043199 NCBI chr14:44,807,875...44,919,780
Ensembl chr14:63,064,402...63,131,303
JBrowse link
G F2 coagulation factor II, thrombin ISO RGD PMID:21041276 RGD:5147774 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157
JBrowse link
G FGFR3 fibroblast growth factor receptor 3 treatment ISO RGD PMID:27159076 RGD:11568056 NCBI chr 4:1,933,172...1,948,742 JBrowse link
G GDF5 growth differentiation factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr20:31,761,199...31,766,229
Ensembl chr20:32,882,094...32,886,899
JBrowse link
G GSR glutathione-disulfide reductase ISO protein:increased expression:synovial fluid RGD PMID:16289733 RGD:10401830 NCBI chr 8:29,990,543...30,040,157
Ensembl chr 8:27,180,300...27,229,557
JBrowse link
G HMGB1 high mobility group box 1 severity ISO protein:increased expression:synovial fluid
mRNA:decreased expression:articular cartilage
RGD PMID:19139395, PMID:21968272 RGD:10402061, RGD:10402184 NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527
JBrowse link
G HMGB2 high mobility group box 2 severity ISO mRNA:decreased expression:articular cartilage RGD PMID:19139395 RGD:10402184 NCBI chr 4:165,559,848...165,562,625
Ensembl chr 4:177,797,457...177,800,952
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 ISO mRNA:decreased expression:blood (human)
mRNA:increased expression:tibial plateaux (mouse)
RGD PMID:9497939, PMID:16139532 RGD:10412655, RGD:10429075 NCBI chr14:82,700,881...82,707,020
Ensembl chr14:102,519,699...102,576,723
JBrowse link
G IGF1 insulin like growth factor 1 disease_progression
severity
ISO protein:decreased expression:plasma (rat)
mRNA:increased expression:meniscus:
RGD PMID:8461919, PMID:9497937, PMID:17133593, PMID:20633672 RGD:10003130, RGD:10045862, RGD:10045868, RGD:10046057 NCBI chr12:99,986,887...100,066,773 JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO RGD PMID:8948288 RGD:10045874 NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974
JBrowse link
G IL1A interleukin 1 alpha ISO protein:increased expression:cartilage cell: RGD PMID:9034998, PMID:9497937, PMID:24534736 RGD:10045944, RGD:10045946, RGD:10046057 NCBI chr2A:89,273,482...89,284,421
Ensembl chr2A:113,784,854...113,795,801
JBrowse link
G IL2 interleukin 2 severity ISO protein:increased expression:synovial fluid: RGD PMID:22035391 RGD:5687147 NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984
JBrowse link
G IL4 interleukin 4 susceptibility ISO DNA:repeat:intron: (rs8179190) (human) RGD PMID:18182309, PMID:24406619 RGD:10402787, RGD:2317291 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581
JBrowse link
G KL klotho susceptibility ISO DNA:SNPs:promoter,exon:395G>A,2998C>T(human) RGD PMID:18465812 RGD:10403041 NCBI chr13:14,272,463...14,321,122
Ensembl chr13:32,702,336...32,751,458
JBrowse link
G LEP leptin ISO protein:decreased expression:serum: RGD PMID:23575542 RGD:10411887 NCBI chr 7:120,230,896...120,248,602
Ensembl chr 7:132,885,011...132,901,519
JBrowse link
G LEPR leptin receptor susceptibility ISO protein:increased expression:serum:
DNA:SNP:cds:668A>G(human)
RGD PMID:23575542 RGD:10411887 NCBI chr 1:64,772,612...64,881,886
Ensembl chr 1:66,693,926...66,764,768
JBrowse link
G LPAR1 lysophosphatidic acid receptor 1 susceptibility ISO DNA:snp:promoter:g.-2820G>A (rs10980705) (human) RGD PMID:18325907 RGD:10054291 NCBI chr 9:82,013,960...82,179,227
Ensembl chr 9:110,179,600...110,279,038
JBrowse link
G LTBP1 latent transforming growth factor beta binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr2A:32,956,937...33,409,286
Ensembl chr2A:33,667,191...34,120,602
JBrowse link
G MMP1 matrix metallopeptidase 1 treatment ISO RGD PMID:21167838 RGD:8549737 NCBI chr11:97,730,545...97,739,190
Ensembl chr11:101,221,393...101,230,104
JBrowse link
G MMP3 matrix metallopeptidase 3 treatment ISO RGD PMID:22114772 RGD:8694098 NCBI chr11:97,776,729...97,784,549
Ensembl chr11:101,267,566...101,275,354
JBrowse link
G PENK proenkephalin treatment ISO RGD PMID:21928671 RGD:10003115 NCBI chr 8:52,864,388...52,870,144
Ensembl chr 8:50,234,170...50,239,949
JBrowse link
G PTGES prostaglandin E synthase ISO RGD PMID:17530714 RGD:2300093 NCBI chr 9:100,865,702...100,880,408
Ensembl chr 9:129,522,547...129,537,020
JBrowse link
G SBNO1 strawberry notch homolog 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr12:120,892,270...120,962,576
Ensembl chr12:125,121,471...125,179,151
JBrowse link
G SLC26A2 solute carrier family 26 member 2 susceptibility ISO DNA:deletion:promoter:-716_-713del4A(human) RGD PMID:11558903 RGD:13208866 NCBI chr 5:145,385,433...145,412,180
Ensembl chr 5:151,391,842...151,412,676
JBrowse link
G TGFA transforming growth factor alpha ISO mRNA:increased expression:cartilage
protein:increased expression:cartilage
RGD PMID:17968906 RGD:2317486 NCBI chr2A:70,510,727...70,617,628
Ensembl chr2A:71,625,196...71,731,461
JBrowse link
G WWP2 WW domain containing E3 ubiquitin protein ligase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr16:50,142,402...50,322,052
Ensembl chr16:69,525,246...69,703,831
JBrowse link
limited scleroderma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV1 caveolin 1 no_association
susceptibility
ISO DNA:SNPs:3' utr, intron: (rs9920, rs729949, rs3815412) (human)
DNA:SNPs:enhancer, intron:multiple
RGD PMID:22402147 RGD:8661768 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655
JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO mRNA,protein:increased expression:skin: RGD PMID:12925209 RGD:8661733 NCBI chr17:22,528,154...22,530,091
Ensembl chr17:22,820,890...22,823,384
JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO mRNA,protein:increased expression:skin: RGD PMID:12925209 RGD:8661733 NCBI chr 3:46,255,725...46,263,285
Ensembl chr 3:47,361,124...47,368,312
JBrowse link
G FAS Fas cell surface death receptor ISO RGD PMID:17102953 RGD:12903974 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612
JBrowse link
G FASLG Fas ligand ISO RGD PMID:17102953 RGD:12903974 NCBI chr 1:148,159,826...148,167,785
Ensembl chr 1:151,868,430...151,876,281
JBrowse link
G IL2 interleukin 2 susceptibility ISO DNA:polymorphism::-384T>G(human) RGD PMID:17444587 RGD:4142872 NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984
JBrowse link
G JAK2 Janus kinase 2 ISO RGD PMID:20808962 RGD:4892610 NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626
JBrowse link
G KDR kinase insert domain receptor ISO protein:increased expression:serum: RGD PMID:19886888 RGD:8551850 NCBI chr 4:68,813,894...68,861,018
Ensembl chr 4:75,377,375...75,427,109
JBrowse link
G PGF placental growth factor ISO protein:increased expression:plasma RGD PMID:22461185 RGD:6483571 NCBI chr14:55,494,152...55,508,066 JBrowse link
G SERPINE1 serpin family E member 1 ISO mRNA,protein:increased expression:skin: RGD PMID:15730388 RGD:13208597 NCBI chr 7:93,267,517...93,279,728
Ensembl chr 7:106,510,130...106,518,450
JBrowse link
G STAT4 signal transducer and activator of transcription 4 no_association
susceptibility
ISO DNA:SNPs:introns: (rs10168266, rs3821236) (human)
DNA:SNP:intron: (rs7574865) (human)
RGD PMID:19286670, PMID:23755762 RGD:8661701, RGD:8661714 NCBI chr2B:78,331,402...78,549,231
Ensembl chr2B:196,247,881...196,366,011
JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member susceptibility ISO RGD PMID:16112028 RGD:1578361 NCBI chr 6:32,394,586...32,408,297
Ensembl chr 6:33,507,332...33,523,750
JBrowse link
Lipodermatosclerosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain ISO mRNA:increased expression:dermis RGD PMID:15727634 RGD:5688298 NCBI chr17:44,274,349...44,291,764
Ensembl chr17:49,150,677...49,166,677
JBrowse link
localized scleroderma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN1A cyclin dependent kinase inhibitor 1A ISO mRNA,protein:increased expression:skin: RGD PMID:15803328 RGD:8662838 NCBI chr 6:36,241,405...36,250,032
Ensembl chr 6:37,436,990...37,445,599
JBrowse link
G CSF3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:15863969 NCBI chr17:17,271,074...17,273,493
Ensembl chr17:17,491,276...17,493,729
JBrowse link
G HGF hepatocyte growth factor treatment ISO RGD PMID:14712301 RGD:8548627 NCBI chr 7:73,667,618...73,738,960
Ensembl chr 7:87,327,798...87,397,811
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO protein:increased expression:serum RGD PMID:7916356 RGD:8158116 NCBI chr19:9,821,402...9,837,021
Ensembl chr19:10,484,414...10,500,605
JBrowse link
G IL13 interleukin 13 ISO protein:increased expression:serum RGD PMID:12920362 RGD:8549537 NCBI chr 5:128,073,863...128,078,453
Ensembl chr 5:134,235,788...134,240,548
JBrowse link
G LMNA lamin A/C ISO CTD Direct Evidence: marker/mechanism CTD PMID:15726408 NCBI chr 1:131,456,819...131,482,275
Ensembl chr 1:135,253,700...135,311,539
JBrowse link
G MMP1 matrix metallopeptidase 1 ISO RGD PMID:9804345 RGD:1582543 NCBI chr11:97,730,545...97,739,190
Ensembl chr11:101,221,393...101,230,104
JBrowse link
G TGFB1 transforming growth factor beta 1 ISO RGD PMID:7510487 RGD:7394847 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:9843018 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381
JBrowse link
nodular nonsuppurative panniculitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SERPINA1 serpin family A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:3259592, PMID:6982619 NCBI chr14:75,001,714...75,014,214
Ensembl chr14:94,334,258...94,345,419
JBrowse link
osteoarthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAA2 acetyl-CoA acyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr18:43,164,504...43,195,038
Ensembl chr18:46,512,374...46,542,737
JBrowse link
G ACAN aggrecan treatment ISO RGD PMID:21853458, PMID:22833446 RGD:11570535, RGD:11570544 NCBI chr15:67,492,494...67,563,265
Ensembl chr15:86,733,853...86,771,420
JBrowse link
G ACO1 aconitase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 9:32,157,763...32,225,116
Ensembl chr 9:32,967,993...33,035,177
JBrowse link
G ADAM12 ADAM metallopeptidase domain 12 susceptibility ISO RGD PMID:15334463 RGD:1625347 NCBI chr10:122,583,989...122,958,895
Ensembl chr10:126,852,441...127,165,048
JBrowse link
G ADAM15 ADAM metallopeptidase domain 15 ISO RGD PMID:15818704 RGD:1559176 NCBI chr 1:130,398,961...130,410,860
Ensembl chr 1:134,008,959...134,020,467
JBrowse link
G ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif 14 ISO DNA:missense mutation:cds: (rs4747096) (human) RGD PMID:18790654 RGD:6771189 NCBI chr10:67,145,400...67,232,934
Ensembl chr10:69,671,222...69,758,229
JBrowse link
G ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif 4 treatment ISO associated with Bone Diseases, Metabolic RGD PMID:22432033 RGD:10043110 NCBI chr 1:136,602,140...136,611,469
Ensembl chr 1:140,514,247...140,523,623
JBrowse link
G ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 treatment
no_association
disease_progression
ISO associated with Bone Diseases, Metabolic
DNA:missense mutation:exon:p.R614H (human)
protein:alternative form:synovium
DNA:missense mutations:exon: (rs226794, rs2830585) (human)
mRNA:increased expression:cartilage
RGD PMID:11801682, PMID:17530714, PMID:18240210, PMID:22084394, PMID:22432033, PMID:22961118, PMID:23546441, PMID:23954517, PMID:23982761 RGD:10003165, RGD:10043101, RGD:10043102, RGD:10043103, RGD:10043105, RGD:10043106, RGD:10043107, RGD:10043110, RGD:2300093 NCBI chr21:13,352,222...13,402,165
Ensembl chr21:26,744,807...26,788,736
JBrowse link
G ADGRG2 adhesion G protein-coupled receptor G2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr  X:11,610,278...11,747,059
Ensembl chr  X:18,973,638...19,054,159
JBrowse link
G AGER advanced glycosylation end-product specific receptor treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:16948116, PMID:23894457 RGD:8695985 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641
JBrowse link
G AK4 adenylate kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 1:64,394,898...64,479,536
Ensembl chr 1:66,283,102...66,361,230
JBrowse link
G ALDH1A2 aldehyde dehydrogenase 1 family member A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24728293 NCBI chr15:36,925,443...37,038,288
Ensembl chr15:55,237,101...55,557,168
JBrowse link
G ASPN asporin susceptibility
no_association
ISO DNA:repeats:exon:
CTD Direct Evidence: marker/mechanism
OMIM
RGD
CTD
PMID:16542493 RGD:9684966 NCBI chr 9:63,579,188...63,605,811
Ensembl chr 9:91,651,629...91,677,969
JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr19:38,854,243...38,882,034 JBrowse link
G ATP6V1B2 ATPase H+ transporting V1 subunit B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 8:19,422,423...19,446,799
Ensembl chr 8:16,369,937...16,394,284
JBrowse link
G BAD BCL2 associated agonist of cell death ISO RGD PMID:19217321 RGD:10053643 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257
JBrowse link
G BAG6 BAG cochaperone 6 susceptibility ISO DNA:SNP: :rs3117582(human) RGD PMID:25231575 RGD:14390133 NCBI chr 6:31,300,126...31,313,829
Ensembl chr 6:32,190,037...32,204,321
JBrowse link
G BAX BCL2 associated X, apoptosis regulator ISO protein:increased expression:chondrocyte RGD PMID:16864079, PMID:19217321 RGD:10053643, RGD:10054095 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468
JBrowse link
G BCL2 BCL2 apoptosis regulator ISO protein:increased expression:chondrocyte RGD PMID:16864079, PMID:19217321 RGD:10053643, RGD:10054095 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100
JBrowse link
G BECN1 beclin 1 ISO protein:decreased expression:cartilage RGD PMID:20187128 RGD:6483317 NCBI chr17:14,493,619...14,507,809
Ensembl chr17:14,719,781...14,733,286
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein disease_progression ISO RGD PMID:20157712 RGD:6483599 NCBI chr 1:131,583,789...131,586,459
Ensembl chr 1:135,413,871...135,416,432
JBrowse link
G BMP2 bone morphogenetic protein 2 susceptibility ISO RGD PMID:15334463 RGD:1625347 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610
JBrowse link
G BMP4 bone morphogenetic protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752
JBrowse link
G BMP6 bone morphogenetic protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr 6:7,564,164...7,720,341
Ensembl chr 6:7,848,249...8,000,649
JBrowse link
G CALCA calcitonin related polypeptide alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:16690336 NCBI chr11:15,055,897...15,061,539
Ensembl chr11:14,745,588...14,751,267
JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:29138829 RGD:13782343 NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185
JBrowse link
G CASP9 caspase 9 treatment ISO RGD PMID:29138829 RGD:13782343 NCBI chr 1:14,630,659...14,662,865
Ensembl chr 1:15,624,666...15,656,266
JBrowse link
G CAV1 caveolin 1 ISO RGD PMID:16508959 RGD:10043354 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655
JBrowse link
G CCL22 C-C motif chemokine ligand 22 ISO protein:increased expression:plasma: RGD PMID:19942450 RGD:10054497 NCBI chr16:37,631,861...37,640,208
Ensembl chr16:56,765,367...56,771,213
JBrowse link
G CCR4 C-C motif chemokine receptor 4 ISO protein:increased expression:synovial membrane: RGD PMID:19942450 RGD:10054497 NCBI chr 3:32,882,419...32,887,442
Ensembl chr 3:33,188,482...33,189,564
JBrowse link
G CD36 CD36 molecule susceptibility ISO RGD PMID:15334463 RGD:1625347 NCBI chr 7:72,566,478...72,643,517
Ensembl chr 7:86,265,114...86,305,865
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A treatment ISO RGD PMID:24009074 RGD:10043190 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G CEBPB CCAAT enhancer binding protein beta susceptibility ISO RGD PMID:22095691 RGD:10401214 NCBI chr20:46,533,163...46,535,282 JBrowse link
G CHI3L1 chitinase 3 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 1:178,778,081...178,789,704
Ensembl chr 1:183,075,312...183,083,229
JBrowse link
G CILP cartilage intermediate layer protein disease_progression ISO RGD PMID:15334463 RGD:1625347 NCBI chr15:44,142,312...44,159,395
Ensembl chr15:62,425,780...62,441,214
JBrowse link
G CLEC3B C-type lectin domain family 3 member B disease_progression ISO RGD PMID:15334463 RGD:1625347 NCBI chr 3:44,927,098...44,936,847
Ensembl chr 3:46,038,115...46,047,927
JBrowse link
G CLIC1 chloride intracellular channel 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 6:31,391,958...31,397,920
Ensembl chr 6:32,280,645...32,286,621
JBrowse link
G CLIC4 chloride intracellular channel 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 1:23,947,030...24,042,139
Ensembl chr 1:24,975,260...25,017,904
JBrowse link
G CLU clusterin ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789, PMID:18784066 NCBI chr 8:26,867,973...26,884,838
Ensembl chr 8:24,070,053...24,083,523
JBrowse link
G COL1A1 collagen type I alpha 1 chain no_association ISO DNA:SNP:intron:IVS1 RGD PMID:10743824 RGD:5688331 NCBI chr17:44,274,349...44,291,764
Ensembl chr17:49,150,677...49,166,677
JBrowse link
G COL1A2 collagen type I alpha 2 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 7:86,344,657...86,381,282
Ensembl chr 7:99,935,185...99,971,803
JBrowse link
G COL2A1 collagen type II alpha 1 chain treatment
onset
ISO CTD Direct Evidence: marker/mechanism
DNA:missense mutation:exon:p.R75C (human)
RGD
CTD
PMID:9061443, PMID:16189708, PMID:16755660, PMID:19216861 RGD:8657384, RGD:8661226 NCBI chr12:40,726,137...40,757,690 JBrowse link
G COL6A2 collagen type VI alpha 2 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr21:32,442,859...32,478,076
Ensembl chr21:45,710,491...45,730,895
JBrowse link
G COMP cartilage oligomeric matrix protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:7670472 NCBI chr19:18,222,270...18,230,936
Ensembl chr19:19,229,562...19,238,008
JBrowse link
G CTSD cathepsin D ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr11:1,789,326...1,800,524 JBrowse link
G CTSK cathepsin K ISO CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chr 1:126,146,555...126,158,662
Ensembl chr 1:129,795,966...129,808,316
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr 4:50,092,989...50,095,541
Ensembl chr 4:55,925,562...55,986,555
JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr 4:50,357,643...50,359,822
Ensembl chr 4:56,189,961...56,192,402
JBrowse link
G DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 4:92,240,003...92,292,624
Ensembl chr 4:102,901,220...102,954,210
JBrowse link
G DDX3X DEAD-box helicase 3 X-linked ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr  X:33,780,381...33,796,829
Ensembl chr  X:41,475,116...41,505,837
JBrowse link
G DPEP1 dipeptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chr16:70,365,900...70,392,377
Ensembl chr16:89,975,105...89,997,978
JBrowse link
G DPYSL2 dihydropyrimidinase like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 8:25,786,950...25,927,782
Ensembl chr 8:22,693,863...22,834,080
JBrowse link
G EDIL3 EGF like repeats and discoidin domains 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 5:30,895,036...31,337,176
Ensembl chr 5:31,215,260...31,654,250
JBrowse link
G EEF2 eukaryotic translation elongation factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr19:3,000,608...3,009,918
Ensembl chr19:3,950,772...3,960,172
JBrowse link
G EGR1 early growth response 1 ISO mRNA, protein: decreased expression RGD PMID:10806043 RGD:1626498 NCBI chr 5:133,845,305...133,849,291
Ensembl chr 5:139,975,635...139,979,260
JBrowse link
G ENO1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 1:7,619,490...7,637,558
Ensembl chr 1:8,855,074...8,873,215
JBrowse link
G EPAS1 endothelial PAS domain protein 1 ISO mRNA:increased expression:cartilage
protein:increased expression:layer of synovial tissue, stromal cell
RGD PMID:12823854, PMID:20495569, PMID:21869830 RGD:10395364, RGD:10395365, RGD:10395366 NCBI chr2A:46,403,411...46,492,734
Ensembl chr2A:47,332,308...47,421,560
JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit ISO mRNA:decreased expression:knee, articular cartilage of joint RGD PMID:24964749 RGD:10045611 NCBI chr19:42,356,039...42,427,754
Ensembl chr19:50,951,674...50,968,430
JBrowse link
G ESD esterase D ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr13:27,915,905...27,942,142
Ensembl chr13:46,633,619...46,659,969
JBrowse link
G ESR1 estrogen receptor 1 ISO DNA:SNPs:introns: (rs2234693, rs9340799) (human)
DNA:SNP:intron: (rs2234693) (human)
RGD PMID:19884274, PMID:20417295 RGD:10045662, RGD:10045830 NCBI chr 6:149,507,599...149,918,523
Ensembl chr 6:154,317,002...154,631,551
JBrowse link
G ESR2 estrogen receptor 2 ISO DNA:SNP:intron: (rs1256031) (human) RGD PMID:19884274 RGD:10045830 NCBI chr14:44,807,875...44,919,780
Ensembl chr14:63,064,402...63,131,303
JBrowse link
G ETFA electron transfer flavoprotein subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr15:55,128,686...55,227,369
Ensembl chr15:74,720,198...74,818,494
JBrowse link
G EZR ezrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 6:156,656,146...156,709,986
Ensembl chr 6:161,670,483...161,723,102
JBrowse link
G FCGR2A Fc fragment of IgG receptor IIa ISO RGD PMID:8254199 RGD:5147984 NCBI chr 1:136,892,311...136,906,450 JBrowse link
G FGF18 fibroblast growth factor 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chr 5:166,765,061...166,802,277 JBrowse link
G FGFR1 fibroblast growth factor receptor 1 ISO RGD PMID:22393163 RGD:10402075 NCBI chr 8:37,713,133...37,773,098
Ensembl chr 8:34,890,147...34,948,904
JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO mRNA:increased expression:trabecular bone: RGD PMID:15781004 RGD:10402109 NCBI chr13:9,584,850...9,779,542 JBrowse link
G FN1 fibronectin 1 ISO protein:increased expression:cartilage: RGD PMID:8646429 RGD:10402156 NCBI chr2B:102,623,568...102,698,747
Ensembl chr2B:221,208,431...221,284,003
JBrowse link
G FRZB frizzled related protein susceptibility ISO ClinVar Annotator: match by term: Osteoarthritis
ClinVar Annotator: match by term: Osteoarthritis susceptibility 1
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:15210948, PMID:25741868 NCBI chr2B:70,106,378...70,139,333
Ensembl chr2B:187,915,579...187,948,855
JBrowse link
G FTL ferritin light chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr19:45,966,431...45,968,015
Ensembl chr19:54,788,854...54,790,465
JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr12:6,665,218...6,669,170
Ensembl chr12:6,583,895...6,587,729
JBrowse link
G GDF5 growth differentiation factor 5 ISO OMIM NCBI chr20:31,761,199...31,766,229
Ensembl chr20:32,882,094...32,886,899
JBrowse link
G GHR growth hormone receptor ISO DNA:deletion:exon: RGD PMID:23740230 RGD:10003113 NCBI chr 5:67,654,326...67,953,140
Ensembl chr 5:72,700,150...72,871,278
JBrowse link
G GLS glutaminase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr2B:78,182,117...78,267,071
Ensembl chr2B:196,098,910...196,183,323
JBrowse link
G GSTK1 glutathione S-transferase kappa 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 7:135,258,184...135,267,254
Ensembl chr 7:147,749,461...147,755,158
JBrowse link
G HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr2A:26,185,938...26,240,229
Ensembl chr2A:26,279,995...26,334,068
JBrowse link
G HBP1 HMG-box transcription factor 1 ISO RGD PMID:22586168 RGD:10402054 NCBI chr 7:99,147,813...99,181,335
Ensembl chr 7:111,873,874...111,906,437
JBrowse link
G HFE homeostatic iron regulator ISO DNA:missense mutation: :p.C282Y (rs1800562) (human) RGD PMID:30651232 RGD:14746965 NCBI chr 6:25,921,663...25,930,852
Ensembl chr 6:26,580,358...26,588,591
JBrowse link
G HIBCH 3-hydroxyisobutyryl-CoA hydrolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr2B:77,510,938...77,652,911 JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO protein:increased expression:layer of synovial tissue, stromal cell RGD PMID:12823854, PMID:18789153 RGD:10395366, RGD:10402406 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885
JBrowse link
G HMGB1 high mobility group box 1 ISO RGD PMID:22330250 RGD:10401949 NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527
JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr15:68,771,050...68,790,523
Ensembl chr15:87,972,889...87,991,276
JBrowse link
G IDH3A isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr15:57,078,588...57,099,934
Ensembl chr15:76,043,311...76,064,634
JBrowse link
G IFNA6 interferon alpha 6 treatment ISO RGD PMID:30456844 RGD:36174218 NCBI chr 9:21,211,046...21,211,734
Ensembl chr 9:21,828,719...21,829,288
JBrowse link
G IGF1 insulin like growth factor 1 ISO protein:decreased expression:blood: RGD PMID:2290165 RGD:10045857 NCBI chr12:99,986,887...100,066,773 JBrowse link
G IGF1R insulin like growth factor 1 receptor severity ISO mRNA:increased expression:articular cartilage of joint: RGD PMID:8609369 RGD:10045889 NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974
JBrowse link
G IGF2 insulin like growth factor 2 ISO mRNA:increased expression:cartilage RGD PMID:22527881 RGD:10402552 NCBI chr11:2,170,190...2,199,442
Ensembl chr11:2,202,743...2,228,890
JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 ISO RGD PMID:18775662 RGD:10402575 NCBI chr 7:46,564,234...46,573,145 JBrowse link
G IHH Indian hedgehog signaling molecule ISO protein:increased expression:cartilage RGD PMID:24786088 RGD:12910979 NCBI chr2B:106,312,472...106,319,124
Ensembl chr2B:224,906,271...224,911,506
JBrowse link
G IL1A interleukin 1 alpha ISO protein:increased expression:chonodrocyte: RGD PMID:9497936 RGD:10047053 NCBI chr2A:89,273,482...89,284,421
Ensembl chr2A:113,784,854...113,795,801
JBrowse link
G IL1B interleukin 1 beta treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:21954917, PMID:22890185 RGD:7207218 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G IL4R interleukin 4 receptor ISO protein:increased expression:serum RGD PMID:16647277 RGD:10402785 Ensembl chr16:27,642,702...27,737,445 JBrowse link
G IL5 interleukin 5 ISO RGD PMID:22035391 RGD:5687147 NCBI chr 5:127,955,377...127,961,726
Ensembl chr 5:134,119,608...134,121,675
JBrowse link
G IMMT inner membrane mitochondrial protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr2A:86,198,027...86,249,909
Ensembl chr2A:87,745,472...87,796,218
JBrowse link
G INS insulin ISO protein:increased expression:blood: RGD PMID:2290165 RGD:10045857 NCBI chr11:2,200,785...2,202,579
Ensembl chr11:2,218,117...2,231,666
JBrowse link
G ISOC2 isochorismatase domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr19:52,496,880...52,507,073
Ensembl chr19:61,185,417...61,196,482
JBrowse link
G JAG1 jagged canonical Notch ligand 1 ISO RGD PMID:18354251 RGD:6482239 NCBI chr20:10,582,234...10,618,507
Ensembl chr20:10,582,094...10,618,383
JBrowse link
G LEP leptin severity ISO protein:increased expression:tibia, cartilage, chondrocyte (human) RGD PMID:14613274 RGD:10053634 NCBI chr 7:120,230,896...120,248,602
Ensembl chr 7:132,885,011...132,901,519
JBrowse link
G LOC100971425 somatotropin ISO protein:increased expression:plasma RGD PMID:7152485 RGD:10003140 NCBI chr17:58,010,848...58,013,421 JBrowse link
G LOC100977237 thioredoxin reductase 1, cytoplasmic ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr12:101,862,703...101,925,104
Ensembl chr12:105,187,128...105,321,112
JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11790802, PMID:12379497 NCBI chr11:60,897,897...60,917,690
Ensembl chr11:64,233,504...64,252,802
JBrowse link
G MATN3 matrilin 3 susceptibility ISO ClinVar Annotator: match by term: OSTEOARTHRITIS OF DISTAL INTERPHALANGEAL JOINTS
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:12736871 NCBI chr2A:19,979,188...20,000,733
Ensembl chr2A:20,095,710...20,116,015
JBrowse link
G MMP1 matrix metallopeptidase 1 ISO protein:increased expression:plasma (human) RGD PMID:9972954 RGD:7207129 NCBI chr11:97,730,545...97,739,190
Ensembl chr11:101,221,393...101,230,104
JBrowse link
G MMP13 matrix metallopeptidase 13 treatment ISO mRNA, protein:increased expression:cartilage RGD PMID:11134178, PMID:16128596, PMID:17530714, PMID:22890185, PMID:23982761 RGD:10043101, RGD:10043117, RGD:2300093, RGD:7207089, RGD:7207218 NCBI chr11:97,890,811...97,902,778
Ensembl chr11:101,377,001...101,387,679
JBrowse link
G MMP2 matrix metallopeptidase 2 ISO protein:increased expression:synovial fluid (human) RGD PMID:15194590 RGD:7207131 NCBI chr16:35,711,866...35,738,881
Ensembl chr16:54,812,694...54,844,279
JBrowse link
G MMP3 matrix metallopeptidase 3 ISO protein:increased expression:synovial fluid (human) RGD PMID:15194590, PMID:16128596 RGD:7207089, RGD:7207131 NCBI chr11:97,776,729...97,784,549
Ensembl chr11:101,267,566...101,275,354
JBrowse link
G MMP8 matrix metallopeptidase 8 ISO protein:increased expression:synovial fluid, serum (human) RGD PMID:15194590 RGD:7207131 NCBI chr11:97,650,408...97,663,731
Ensembl chr11:101,143,268...101,156,736
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO protein:increased expression:synovial fluid, serum (human) RGD PMID:15194590 RGD:7207131 NCBI chr20:42,346,305...42,354,018
Ensembl chr20:43,432,389...43,440,129
JBrowse link
G MSN moesin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr  X:54,785,309...54,859,364
Ensembl chr  X:64,781,550...64,933,292
JBrowse link
G MTOR mechanistic target of rapamycin kinase treatment ISO RGD PMID:22084394, PMID:24651621 RGD:10003163, RGD:10003165 NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841
JBrowse link
G MVP major vault protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 Ensembl chr16:30,190,090...30,219,070 JBrowse link
G MYH13 myosin heavy chain 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr17:41,288,536...41,351,827
Ensembl chr17:46,035,614...46,098,800
JBrowse link
G NAPEPLD N-acyl phosphatidylethanolamine phospholipase D ISO protein:increased expression:spinal cord RGD PMID:20722027 RGD:10412653 NCBI chr 7:95,074,084...95,123,936
Ensembl chr 7:107,923,960...107,973,269
JBrowse link
G NCOR2 nuclear receptor corepressor 2 susceptibility ISO RGD PMID:15334463 RGD:1625347 NCBI chr12:121,913,368...122,155,031
Ensembl chr12:126,201,779...126,372,745
JBrowse link
G NDUFS8 NADH:ubiquinone oxidoreductase core subunit S8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr11:63,112,536...63,118,600
Ensembl chr11:66,421,378...66,427,101
JBrowse link
G NDUFV1 NADH:ubiquinone oxidoreductase core subunit V1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr11:62,964,970...62,970,605
Ensembl chr11:66,276,638...66,282,320
JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 3:190,890,242...190,995,133
Ensembl chr 3:201,207,607...201,312,358
JBrowse link
G P3H3 prolyl 3-hydroxylase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr12:6,960,193...6,971,691
Ensembl chr12:6,872,035...6,883,187
JBrowse link
G PDCD6IP programmed cell death 6 interacting protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 3:33,719,603...33,793,301
Ensembl chr 3:34,016,474...34,093,631
JBrowse link
G PDHA1 pyruvate dehydrogenase E1 subunit alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr  X:11,967,944...11,985,837
Ensembl chr  X:19,330,508...19,348,443
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO mRNA:increased expression:tibia (rat) RGD PMID:21864409 RGD:6771362 NCBI chr17:58,417,134...58,526,409
Ensembl chr17:63,511,784...63,579,067
JBrowse link
G PLCD1 phospholipase C delta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 3:37,906,359...37,928,564
Ensembl chr 3:38,189,496...38,206,886
JBrowse link
G PLOD2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 3:143,091,833...143,181,831
Ensembl chr 3:150,675,424...150,764,939
JBrowse link
G PLS3 plastin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr  X:104,656,110...104,745,702
Ensembl chr  X:115,160,032...115,250,144
JBrowse link
G POMC proopiomelanocortin ISO RGD PMID:21378032 RGD:5508809 NCBI chr2A:25,161,668...25,165,600
Ensembl chr2A:25,258,768...25,262,706
JBrowse link
G POU3F3 POU class 3 homeobox 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr2A:96,967,943...96,972,378 JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 3:12,215,322...12,361,669
Ensembl chr 3:12,622,397...12,705,060
JBrowse link
G PPP2R1A protein phosphatase 2 scaffold subunit Aalpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr19:49,133,295...49,169,447
Ensembl chr19:58,011,383...58,047,577
JBrowse link
G PSMB1 proteasome 20S subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 6:168,695,047...168,713,257
Ensembl chr 6:173,781,040...173,799,342
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 susceptibility ISO DNA:SNP (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:15334463, PMID:32004530 RGD:1625347 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519
JBrowse link
G RAN RAN, member RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr12:128,497,407...128,503,049
Ensembl chr12:132,694,498...132,699,668
JBrowse link
G RCN3 reticulocalbin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr19:46,540,352...46,556,508
Ensembl chr19:55,463,535...55,477,478
JBrowse link
G RUNX2 RUNX family transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr 6:45,003,962...45,133,148
Ensembl chr 6:46,189,432...46,524,389
JBrowse link
G S100A4 S100 calcium binding protein A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16948116 NCBI chr 1:128,898,765...128,901,042
Ensembl chr 1:132,527,846...132,530,122
JBrowse link
G SCRN1 secernin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 7:30,550,199...30,619,197
Ensembl chr 7:30,667,229...30,736,129
JBrowse link
G SDCBP syndecan binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 8:54,992,627...55,022,560
Ensembl chr 8:56,643,962...56,673,833
JBrowse link
G SDHA succinate dehydrogenase complex flavoprotein subunit A ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 5:192,786...234,089 JBrowse link
G SEC23A Sec23 homolog A, COPII coat complex component ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr14:19,802,612...19,873,076
Ensembl chr14:38,159,381...38,229,550
JBrowse link
G SERPINA1 serpin family A member 1 ISO RGD PMID:20434574 RGD:2324964 NCBI chr14:75,001,714...75,014,214
Ensembl chr14:94,334,258...94,345,419
JBrowse link
G SGCG sarcoglycan gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr13:4,471,680...4,638,419
Ensembl chr13:22,810,771...22,932,350
JBrowse link
G SLC2A1 solute carrier family 2 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18973239 NCBI chr 1:42,224,273...42,257,184
Ensembl chr 1:43,600,733...43,634,143
JBrowse link
G SMAD3 SMAD family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21217753, PMID:22772368 NCBI chr15:46,013,764...46,143,126
Ensembl chr15:64,284,949...64,414,185
JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15292528, PMID:18784066, PMID:22108257 NCBI chr 6:157,562,814...157,610,155
Ensembl chr 6:162,576,082...162,589,960
JBrowse link
G TENT5A terminal nucleotidyltransferase 5A susceptibility ISO DNA:repeats: : RGD PMID:25231575 RGD:14390133 NCBI chr 6:79,636,412...79,643,444
Ensembl chr 6:82,901,079...82,908,072
JBrowse link
G TFPI2 tissue factor pathway inhibitor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr 7:85,835,141...85,839,515
Ensembl chr 7:99,426,006...99,431,099
JBrowse link
G TGFB1 transforming growth factor beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G TGM2 transglutaminase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr20:34,450,845...34,488,106
Ensembl chr20:35,561,819...35,599,042
JBrowse link
G TLR8 toll like receptor 8 ISO ClinVar Annotator: match by term: Osteoarthritis ClinVar NCBI chr  X:5,518,742...5,535,304 JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a ISO RGD PMID:14872496 RGD:2290500 NCBI chr 8:22,440,502...22,476,790
Ensembl chr 8:19,378,547...19,414,724
JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b disease_progression ISO RGD PMID:15334463 RGD:1625347 NCBI chr 8:115,614,778...115,643,387
Ensembl chr 8:118,134,305...118,162,422
JBrowse link
G TNFSF10 TNF superfamily member 10 ISO RGD PMID:14872496 RGD:2290500 NCBI chr 3:169,512,491...169,530,706
Ensembl chr 3:177,694,021...177,712,137
JBrowse link
G TNFSF15 TNF superfamily member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chr 9:85,881,800...85,904,191
Ensembl chr 9:114,249,472...114,265,441
JBrowse link
G TRAP1 TNF receptor associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr16:2,578,483...2,637,996
Ensembl chr16:3,753,799...3,786,429
JBrowse link
G TRIM2 tripartite motif containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 4:145,494,088...145,681,287
Ensembl chr 4:157,194,729...157,500,723
JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21964574 NCBI chr12:107,359,005...107,409,359
Ensembl chr12:110,754,238...110,786,182
JBrowse link
G VDAC2 voltage dependent anion channel 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr10:71,739,395...71,763,835 JBrowse link
G VIM vimentin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16876394, PMID:18784066 NCBI chr10:17,546,389...17,554,702
Ensembl chr10:17,818,285...17,826,642
JBrowse link
G YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta ISO CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr2A:9,573,413...9,620,495 JBrowse link
Osteoarthritis with Mild Chondrodysplasia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL2A1 collagen type II alpha 1 chain ISO OMIM NCBI chr12:40,726,137...40,757,690 JBrowse link
Osteoarthritis, Experimental term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BECN1 beclin 1 treatment ISO RGD PMID:23589102 RGD:11561955 NCBI chr17:14,493,619...14,507,809
Ensembl chr17:14,719,781...14,733,286
JBrowse link
G BMP4 bone morphogenetic protein 4 ISO RGD PMID:19404941 RGD:9068434 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752
JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:29621761 RGD:13782275 NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185
JBrowse link
G CASP6 caspase 6 treatment ISO RGD PMID:29621761 RGD:13782275 NCBI chr 4:102,186,215...102,201,992
Ensembl chr 4:112,753,988...112,768,836
JBrowse link
G CASP7 caspase 7 treatment ISO RGD PMID:29621761 RGD:13782275 NCBI chr10:110,273,318...110,324,800
Ensembl chr10:113,707,780...113,758,626
JBrowse link
G CASP8 caspase 8 treatment ISO RGD PMID:29621761 RGD:13782275 NCBI chr2B:88,490,611...88,542,132
Ensembl chr2B:206,669,544...206,696,468
JBrowse link
G COL1A1 collagen type I alpha 1 chain treatment ISO RGD PMID:25128628 RGD:11041187 NCBI chr17:44,274,349...44,291,764
Ensembl chr17:49,150,677...49,166,677
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 ISO RGD PMID:22833219 RGD:10402072 NCBI chr 8:37,713,133...37,773,098
Ensembl chr 8:34,890,147...34,948,904
JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 ISO RGD PMID:23041435 RGD:10402106 NCBI chr13:9,584,850...9,779,542 JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A treatment ISO RGD PMID:16394269 RGD:10402538 NCBI chr 6:31,476,710...31,491,411 JBrowse link
G LRPAP1 LDL receptor related protein associated protein 1 ISO mRNA:decreased expression:knee RGD PMID:24754147 RGD:10412054 NCBI chr 4:3,663,649...3,683,450
Ensembl chr 4:3,646,179...3,666,098
JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha treatment ISO RGD PMID:23589102 RGD:11561955 NCBI chr20:30,887,345...30,888,986
Ensembl chr20:32,010,284...32,020,411
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO RGD PMID:29364174 RGD:13800565 Ensembl chr16:30,489,362...30,498,017 JBrowse link
G SERPINF1 serpin family F member 1 severity ISO RGD PMID:28122611 RGD:27226703 NCBI chr17:1,745,597...1,761,399
Ensembl chr17:1,638,556...1,653,568
JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 treatment ISO RGD PMID:23589102 RGD:11561955 NCBI chr12:129,549,399...129,579,087 JBrowse link
Osteoarthritis, Hip term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 ISO mRNA:increased expression:cartilage RGD PMID:22670655 RGD:10043109 NCBI chr21:13,352,222...13,402,165
Ensembl chr21:26,744,807...26,788,736
JBrowse link
G ASPN asporin ISO DNA:repeats:exon: RGD PMID:15640800 RGD:9684965 NCBI chr 9:63,579,188...63,605,811
Ensembl chr 9:91,651,629...91,677,969
JBrowse link
G ASTN2 astrotactin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr 9:87,558,337...88,538,570
Ensembl chr 9:115,912,657...116,890,931
JBrowse link
G CHADL chondroadherin like ISO CTD Direct Evidence: marker/mechanism CTD PMID:28319091, PMID:30374069 NCBI chr22:22,106,953...22,138,122 JBrowse link
G COL10A1 collagen type X alpha 1 chain ISO mRNA, protein:increased expression:cartilage RGD PMID:22670655 RGD:10043109 NCBI chr 6:113,921,538...113,961,490
Ensembl chr 6:118,067,477...118,074,684
JBrowse link
G COL11A1 collagen type XI alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr 1:105,538,215...105,769,973
Ensembl chr 1:104,249,891...104,481,259
JBrowse link
G COL1A1 collagen type I alpha 1 chain susceptibility
no_association
ISO DNA:SNP:intron:g.2046G>T (human) RGD PMID:9811048, PMID:15880349, PMID:17187661 RGD:5688305, RGD:5688306, RGD:5688330 NCBI chr17:44,274,349...44,291,764
Ensembl chr17:49,150,677...49,166,677
JBrowse link
G COMP cartilage oligomeric matrix protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:28319091 NCBI chr19:18,222,270...18,230,936
Ensembl chr19:19,229,562...19,238,008
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chr17:11,261,435...11,313,630 JBrowse link
G DIABLO diablo IAP-binding mitochondrial protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chr12:119,808,718...119,829,378
Ensembl chr12:123,176,405...123,196,359
JBrowse link
G ESR1 estrogen receptor 1 ISO DNA:SNP:intron:g.-397T>C (human) RGD PMID:17419075 RGD:10045661 NCBI chr 6:149,507,599...149,918,523
Ensembl chr 6:154,317,002...154,631,551
JBrowse link
G FILIP1 filamin A interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr 6:73,135,086...73,334,630
Ensembl chr 6:76,429,175...76,548,549
JBrowse link
G GDF5 growth differentiation factor 5 ISO ClinVar Annotator: match by term: Osteoarthritis of hip ClinVar PMID:17384641 NCBI chr20:31,761,199...31,766,229
Ensembl chr20:32,882,094...32,886,899
JBrowse link
G GHR growth hormone receptor ISO associated with Acromegaly;DNA:deletion:exon: RGD PMID:19864451 RGD:10003142 NCBI chr 5:67,654,326...67,953,140
Ensembl chr 5:72,700,150...72,871,278
JBrowse link
G HDAC9 histone deacetylase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr 7:18,740,580...19,653,615
Ensembl chr 7:18,138,761...18,970,717
JBrowse link
G HFE homeostatic iron regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr 6:25,921,663...25,930,852
Ensembl chr 6:26,580,358...26,588,591
JBrowse link
G IL11 interleukin 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069, PMID:30664745 NCBI chr19:52,407,730...52,426,445
Ensembl chr19:61,096,275...61,101,837
JBrowse link
G IL4R interleukin 4 receptor susceptibility
no_association
ISO DNA:SNPs:multiple
DNA:missense mutations:cds:p.S411L, p.S727A (rs1805013, rs1805016) (human)
RGD PMID:14745651, PMID:19036616 RGD:10402782, RGD:10402784 Ensembl chr16:27,642,702...27,737,445 JBrowse link
G ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr 3:52,719,065...52,733,507
Ensembl chr 3:53,945,141...53,959,378
JBrowse link
G LMX1B LIM homeobox transcription factor 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr 9:97,730,850...97,820,554
Ensembl chr 9:126,240,722...126,322,420
JBrowse link
G LOC100977568 tenascin ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr 9:86,125,672...86,222,804
Ensembl chr 9:114,486,778...114,584,299
JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr11:60,897,897...60,917,690
Ensembl chr11:64,233,504...64,252,802
JBrowse link
G MAPT microtubule associated protein tau ISO CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chr17:11,373,220...11,506,669
Ensembl chr17:11,458,159...11,523,129
JBrowse link
G MMP13 matrix metallopeptidase 13 ISO mRNA, protein:increased expression:cartilage RGD PMID:22670655 RGD:10043109 NCBI chr11:97,890,811...97,902,778
Ensembl chr11:101,377,001...101,387,679
JBrowse link
G RUNX2 RUNX family transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr 6:45,003,962...45,133,148
Ensembl chr 6:46,189,432...46,524,389
JBrowse link
G SMAD3 SMAD family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr15:46,013,764...46,143,126
Ensembl chr15:64,284,949...64,414,185
JBrowse link
G SMO smoothened, frizzled class receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr 7:121,143,968...121,168,873
Ensembl chr 7:133,668,304...133,693,048
JBrowse link
Osteoarthritis, Temporomandibular Joint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF6 activating transcription factor 6 ISO mRNA,protein:increased expression:chondrocyte RGD PMID:31007149 RGD:34888237 NCBI chr 1:137,178,629...137,382,256
Ensembl chr 1:140,977,750...141,176,725
JBrowse link
G BECN1 beclin 1 ISO RGD PMID:31007149 RGD:34888237 NCBI chr17:14,493,619...14,507,809
Ensembl chr17:14,719,781...14,733,286
JBrowse link
G DDIT3 DNA damage inducible transcript 3 ISO mRNA,protein:increased expression:chondrocyte RGD PMID:31007149 RGD:34888237 NCBI chr12:31,406,332...31,410,293
Ensembl chr12:31,664,743...31,668,701
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO mRNA,protein:increased expression:chondrocyte RGD PMID:31007149 RGD:34888237 NCBI chr2A:87,688,732...87,759,580
Ensembl chr2A:89,596,833...89,667,468
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 ISO RGD PMID:31007149 RGD:34888237 NCBI chr17:58,132,889...58,224,012
Ensembl chr17:63,226,949...63,317,825
JBrowse link
G FAS Fas cell surface death receptor ISO mRNA:increased expression:mandibular condyle, cartilage (rat) RGD PMID:23934157 RGD:8663479 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO mRNA,protein:increased expression:chondrocyte RGD PMID:31007149 RGD:34888237 NCBI chr 9:96,351,645...96,356,761
Ensembl chr 9:124,865,211...124,870,458
JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta ISO RGD PMID:31007149 RGD:34888237 NCBI chr16:68,063,869...68,076,772 JBrowse link
G RPS6 ribosomal protein S6 ISO RGD PMID:31007149 RGD:34888237 NCBI chr 9:19,185,455...19,189,504
Ensembl chr 9:19,674,380...19,677,722
JBrowse link
otulipenia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OTULIN OTU deubiquitinase with linear linkage specificity ISO OMIM NCBI chr 5:14,969,432...15,017,666
Ensembl chr 5:14,809,539...14,837,750
JBrowse link
polymyalgia rheumatica term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRH corticotropin releasing hormone no_association ISO DNA:polymorphism:promoter RGD PMID:12051390 RGD:1581301 NCBI chr 8:62,714,721...62,716,979
Ensembl chr 8:64,383,419...64,384,009
JBrowse link
G CRP C-reactive protein treatment ISO RGD PMID:2859021 RGD:9495925 NCBI chr 1:135,062,102...135,064,402 JBrowse link
G HFE homeostatic iron regulator ISO DNA:missense mutation: :p.C282Y (rs1800562) (human) RGD PMID:30657865 RGD:14746966 NCBI chr 6:25,921,663...25,930,852
Ensembl chr 6:26,580,358...26,588,591
JBrowse link
G MBL2 mannose binding lectin 2 ISO DNA:polymorphism:cds: RGD PMID:12375325 RGD:8693752 NCBI chr10:49,401,364...49,409,328
Ensembl chr10:51,527,758...51,543,432
JBrowse link
G MMP3 matrix metallopeptidase 3 ISO RGD PMID:11796404 RGD:7241254 NCBI chr11:97,776,729...97,784,549
Ensembl chr11:101,267,566...101,275,354
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO protein:increased expression:plasma, endothelial microparticle (human) RGD PMID:22211720 RGD:6771319 NCBI chr17:58,417,134...58,526,409
Ensembl chr17:63,511,784...63,579,067
JBrowse link
Reynolds Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LBR lamin B receptor ISO OMIM NCBI chr 1:200,865,602...200,892,199
Ensembl chr 1:205,870,394...205,893,032
JBrowse link
rheumatic fever term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GC GC vitamin D binding protein ISO RGD PMID:2737695 RGD:5509933 NCBI chr 4:52,431,196...52,473,762
Ensembl chr 4:58,729,236...58,792,073
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO protein:increased expression:serum RGD PMID:14567831 RGD:13702910 NCBI chr19:9,821,402...9,837,021
Ensembl chr19:10,484,414...10,500,605
JBrowse link
G LOC100972994 HLA class II histocompatibility antigen, DQ beta 1 chain ISO DNA:polymorphisms, haplotypes:multiple RGD PMID:17559688 RGD:5147792 NCBI chr 6:32,237,395...32,244,201
Ensembl chr 6:33,353,599...33,360,272
JBrowse link
rheumatic heart disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD36 CD36 molecule ISO mRNA:decreased expression:blood, mononuclear cell RGD PMID:16741676 RGD:6893529 NCBI chr 7:72,566,478...72,643,517
Ensembl chr 7:86,265,114...86,305,865
JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase ISO RGD PMID:26823728 RGD:13792679 NCBI chr12:6,665,218...6,669,170
Ensembl chr12:6,583,895...6,587,729
JBrowse link
G IGF1 insulin like growth factor 1 ISO RGD PMID:16406300 RGD:1582623 NCBI chr12:99,986,887...100,066,773 JBrowse link
G IL10 interleukin 10 no_association ISO RGD PMID:16043936 RGD:1598626 NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371
JBrowse link
G LOC100972994 HLA class II histocompatibility antigen, DQ beta 1 chain ISO DNA:polymorphisms:cds:HLA-DQB1*08 (human) RGD PMID:17578051 RGD:5147630 NCBI chr 6:32,237,395...32,244,201
Ensembl chr 6:33,353,599...33,360,272
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO RGD PMID:16406300 RGD:1582623 NCBI chr20:42,346,305...42,354,018
Ensembl chr20:43,432,389...43,440,129
JBrowse link
rheumatic myocarditis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ICAM1 intercellular adhesion molecule 1 severity ISO protein:increased expression:serum RGD PMID:22987107 RGD:13702907 NCBI chr19:9,821,402...9,837,021
Ensembl chr19:10,484,414...10,500,605
JBrowse link
G SELE selectin E severity ISO protein:increased expression:serum RGD PMID:22987107 RGD:13702907 NCBI chr 1:145,205,684...145,217,143
Ensembl chr 1:148,930,437...148,938,313
JBrowse link
G VCAM1 vascular cell adhesion molecule 1 severity ISO protein:increased expression:serum RGD PMID:22987107 RGD:13702907 NCBI chr 1:103,377,815...103,395,118
Ensembl chr 1:102,091,336...102,107,732
JBrowse link
rheumatoid arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20080907, PMID:22104130 NCBI chr 7:79,497,536...79,706,277
Ensembl chr 7:93,147,950...93,243,238
JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr10:96,385,534...96,458,571
Ensembl chr10:99,889,160...99,947,270
JBrowse link
G ABCC4 ATP binding cassette subfamily C member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr13:76,193,929...76,476,119
Ensembl chr13:95,349,915...95,582,058
JBrowse link
G ABCC5 ATP binding cassette subfamily C member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr 3:180,956,139...181,054,112
Ensembl chr 3:189,122,590...189,219,492
JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (Junior blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr 4:80,379,108...80,446,641
Ensembl chr 4:91,101,321...91,170,157
JBrowse link
G ACAN aggrecan disease_progression ISO protein:increased degradation:cartilage
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:15292528, PMID:16507130 RGD:11570537 NCBI chr15:67,492,494...67,563,265
Ensembl chr15:86,733,853...86,771,420
JBrowse link
G ACKR3 atypical chemokine receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr2B:123,795,664...123,810,067
Ensembl chr2B:242,666,173...242,667,261
JBrowse link
G ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif 4 ISO mRNA:increased expression:synovium RGD PMID:11801682 RGD:10043106 NCBI chr 1:136,602,140...136,611,469
Ensembl chr 1:140,514,247...140,523,623
JBrowse link
G ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 ISO protein:alternative form:synovium RGD PMID:11801682 RGD:10043106 NCBI chr21:13,352,222...13,402,165
Ensembl chr21:26,744,807...26,788,736
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:serum
CTD
RGD
PMID:12833524, PMID:21789720 RGD:5686424 NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885
JBrowse link
G ADORA2A adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr22:5,233,876...5,248,622
Ensembl chr22:22,104,253...22,114,189
JBrowse link
G ADRB3 adrenoceptor beta 3 ISO DNA:missense mutation:cds:p.W64R rs4994 (human) RGD PMID:12739037 RGD:5684893 NCBI chr 8:37,263,730...37,267,475 JBrowse link
G AFF3 AF4/FMR2 family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842, PMID:23143596 Ensembl chr2A:100,535,363...100,993,626 JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO protein:decreased expression:plasma (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:16385501, PMID:20541603 RGD:7244141 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641
JBrowse link
G AHR aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18617548 NCBI chr 7:17,949,254...17,998,737 JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr10:42,461,398...42,531,576
Ensembl chr10:45,639,946...45,710,016
JBrowse link
G ANG angiogenin ISO RGD PMID:12653852 RGD:6892721 NCBI chr14:1,548,693...1,558,528
Ensembl chr14:19,614,950...19,615,393
JBrowse link
G ANKRD55 ankyrin repeat domain 55 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 5:57,788,013...57,923,070
Ensembl chr 5:59,416,641...59,550,255
JBrowse link
G ANXA3 annexin A3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr 4:45,585,873...45,644,783
Ensembl chr 4:51,432,846...51,491,677
JBrowse link
G APOA4 apolipoprotein A4 ISO protein:increased expression:blood serum (human) RGD PMID:20367977 RGD:5685646 NCBI chr11:111,659,186...111,661,790
Ensembl chr11:115,591,788...115,594,382
JBrowse link
G ARID5B AT-rich interaction domain 5B ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963, PMID:23143596 NCBI chr10:58,426,519...58,621,986
Ensembl chr10:60,756,484...60,952,174
JBrowse link
G ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19193698 NCBI chr2B:102,574,700...102,612,492
Ensembl chr2B:221,159,439...221,197,360
JBrowse link
G B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr2A:62,276,662...62,305,286
Ensembl chr2A:63,435,289...63,436,482
JBrowse link
G B3GNT9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr16:47,493,804...47,497,908
Ensembl chr16:66,883,954...66,885,162
JBrowse link
G BAIAP2L1 BAR/IMD domain containing adaptor protein 2 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 7:6,158,306...6,230,903
Ensembl chr 7:103,758,479...103,828,874
JBrowse link
G BCL2A1 BCL2 related protein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr15:58,925,853...58,935,122
Ensembl chr15:77,882,940...77,893,628
JBrowse link
G BDKRB2 bradykinin receptor B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr14:76,832,833...76,873,860
Ensembl chr14:96,156,494...96,196,253
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein ISO protein:increased expression:serum RGD PMID:3488088, PMID:22447331 RGD:6483593, RGD:6483600 NCBI chr 1:131,583,789...131,586,459
Ensembl chr 1:135,413,871...135,416,432
JBrowse link
G BGN biglycan ISO CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr  X:143,045,298...143,059,892
Ensembl chr  X:152,931,608...152,946,292
JBrowse link
G BLK BLK proto-oncogene, Src family tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842, PMID:23143596 NCBI chr 8:7,637,680...7,708,914 JBrowse link
G BMP4 bone morphogenetic protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752
JBrowse link
G BMP6 bone morphogenetic protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr 6:7,564,164...7,720,341
Ensembl chr 6:7,848,249...8,000,649
JBrowse link
G BTNL2 butyrophilin like 2 susceptibility ISO DNA:SNPs: : RGD PMID:23364395 RGD:9685033 NCBI chr 6:32,067,223...32,126,032 JBrowse link
G C3 complement C3 ISO RGD PMID:7561187 RGD:11040775 NCBI chr19:5,708,211...5,753,178
Ensembl chr19:6,629,287...6,674,699
JBrowse link
G CALD1 caldesmon 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr 7:126,743,466...126,935,412
Ensembl chr 7:139,337,692...139,440,643
JBrowse link
G CASP7 caspase 7 ISO RGD PMID:18785314 RGD:5684540 NCBI chr10:110,273,318...110,324,800
Ensembl chr10:113,707,780...113,758,626
JBrowse link
G CAST calpastatin ISO RGD PMID:7706496 RGD:5683620 NCBI chr 5:91,972,572...92,084,657
Ensembl chr 5:97,527,071...97,636,650
JBrowse link
G CAT catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22450443 NCBI chr11:34,413,253...34,446,831
Ensembl chr11:34,289,603...34,323,160
JBrowse link
G CAV2 caveolin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr 7:108,254,074...108,480,716
Ensembl chr 7:121,168,579...121,177,415
JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO protein:increased expression:serum RGD PMID:20056091 RGD:4891442 NCBI chr17:22,528,154...22,530,091
Ensembl chr17:22,820,890...22,823,384
JBrowse link
G CCL21 C-C motif chemokine ligand 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18794853, PMID:20453842, PMID:23143596 NCBI chr 9:34,545,248...34,546,801
Ensembl chr 9:35,353,768...35,354,924
JBrowse link
G CCL22 C-C motif chemokine ligand 22 ISO protein:increased expression:plasma: RGD PMID:19942450 RGD:10054497 NCBI chr16:37,631,861...37,640,208
Ensembl chr16:56,765,367...56,771,213
JBrowse link
G CCL8 C-C motif chemokine ligand 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr17:22,468,080...22,470,443
Ensembl chr17:22,761,064...22,763,933
JBrowse link
G CCN1 cellular communication network factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 1:118,138,739...118,141,681
Ensembl chr 1:86,994,296...86,997,147
JBrowse link
G CCN2 cellular communication network factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 6:129,729,572...129,733,113
Ensembl chr 6:133,836,319...133,842,077
JBrowse link
G CCR1 C-C motif chemokine receptor 1 ISO RGD PMID:12860725 RGD:5688170 NCBI chr 3:46,107,526...46,114,229
Ensembl chr 3:47,214,688...47,215,755
JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO protein:increased expression:synovial fluid, neutrophil RGD PMID:19017998 RGD:4145632 NCBI chr 3:46,147,928...46,172,947
Ensembl chr 3:47,253,878...47,278,630
JBrowse link
G CCR4 C-C motif chemokine receptor 4 ISO mRNA:increased expression:synovium:
protein:increased expression:synovial membrane:
RGD PMID:19942450, PMID:25430645 RGD:10054497, RGD:10054499 NCBI chr 3:32,882,419...32,887,442
Ensembl chr 3:33,188,482...33,189,564
JBrowse link
G CCR5 C-C motif chemokine receptor 5 no_association
resistance
ISO DNA:frameshift mutation:cds:p.S185_T195del rs333 (human) RGD PMID:16541097, PMID:17565662 RGD:1626283, RGD:1626290 NCBI chr 3:46,273,096...46,278,471
Ensembl chr 3:47,380,321...47,381,379
JBrowse link
G CCR6 C-C motif chemokine receptor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453841, PMID:20453842, PMID:23143596 NCBI chr 6:165,094,563...165,109,774
Ensembl chr 6:170,069,689...170,084,779
JBrowse link
G CD2 CD2 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 1:85,752,522...85,767,323
Ensembl chr 1:120,749,918...120,764,659
JBrowse link
G CD244 CD244 molecule susceptibility ISO ClinVar Annotator: match by term: Rheumatoid arthritis
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:18794858 NCBI chr 1:136,186,906...136,219,669
Ensembl chr 1:140,110,808...140,123,065
JBrowse link
G CD28 CD28 molecule ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:19075187, PMID:19898481, PMID:20453842, PMID:23143596 RGD:5131619 NCBI chr2B:90,938,795...90,971,438
Ensembl chr2B:209,076,388...209,111,213
JBrowse link
G CD3E CD3e molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr11:113,142,200...113,153,928
Ensembl chr11:117,074,041...117,085,625
JBrowse link
G CD40 CD40 molecule ISO DNA:SNP: :rs4810485 (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:18794853, PMID:20453842, PMID:20498205, PMID:23143596 RGD:5490972 NCBI chr20:42,455,711...42,467,139
Ensembl chr20:43,541,619...43,552,994
JBrowse link
G CD5 CD5 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr11:56,362,415...56,388,469
Ensembl chr11:59,801,808...59,826,448
JBrowse link
G CD80 CD80 molecule ISO protein:increased expression:serum RGD PMID:22917707 RGD:6893647 NCBI chr 3:116,646,590...116,683,725
Ensembl chr 3:123,559,559...123,594,870
JBrowse link
G CD83 CD83 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr 6:13,961,342...13,980,686
Ensembl chr 6:14,330,752...14,349,946
JBrowse link
G CDK6 cyclin dependent kinase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18794853 NCBI chr 7:84,603,419...84,835,082 JBrowse link
G CEBPB CCAAT enhancer binding protein beta ISO protein:increased expression:knee, articular cartilage (human) RGD PMID:19248099 RGD:10401213 NCBI chr20:46,533,163...46,535,282 JBrowse link
G CHI3L1 chitinase 3 like 1 severity ISO protein:increased secretion:serum (human) RGD PMID:10461474 RGD:4892605 NCBI chr 1:178,778,081...178,789,704
Ensembl chr 1:183,075,312...183,083,229
JBrowse link
G CIITA class II major histocompatibility complex transactivator susceptibility
no_association
ISO ClinVar Annotator: match by term: Rheumatoid arthritis
DNA:haplotype:promoter/CDS:rs3087456G/rs4774C
DNA:polymorphism:promoter:rs3087456, no association in a German cohort
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
RGD
CTD
PMID:15821736, PMID:16426246, PMID:16849401, PMID:19221398 RGD:5491176, RGD:5491189 NCBI chr16:9,819,440...9,885,379
Ensembl chr16:11,041,434...11,090,485
JBrowse link
G CLEC12A C-type lectin domain family 12 member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr12:9,999,334...10,056,108
Ensembl chr12:10,248,209...10,272,070
JBrowse link
G CLEC16A C-type lectin domain containing 16A ISO DNA:polymorphism:intron:rs6498169G RGD PMID:19221398 RGD:5491176 NCBI chr16:9,887,877...10,124,500
Ensembl chr16:11,109,869...11,343,512
JBrowse link
G COL2A1 collagen type II alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:27028940, PMID:29935983 NCBI chr12:40,726,137...40,757,690 JBrowse link
G CP ceruloplasmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:26001728 NCBI chr 3:146,180,527...146,239,833
Ensembl chr 3:153,764,830...153,817,544
JBrowse link
G CRP C-reactive protein ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:1568518, PMID:22173958 RGD:6904209 NCBI chr 1:135,062,102...135,064,402 JBrowse link
G CSF2 colony stimulating factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr 5:127,496,951...127,499,325
Ensembl chr 5:133,660,775...133,663,146
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842, PMID:23143596 NCBI chr2B:91,054,917...91,106,234
Ensembl chr2B:209,239,417...209,244,498
JBrowse link
G CTSD cathepsin D ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr11:1,789,326...1,800,524 JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 ISO RGD PMID:11465708 RGD:4892002 NCBI chr16:37,646,447...37,659,078
Ensembl chr16:56,779,065...56,791,760
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr 4:50,092,989...50,095,541
Ensembl chr 4:55,925,562...55,986,555
JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr 4:50,357,643...50,359,822
Ensembl chr 4:56,189,961...56,192,402
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860, PMID:19192274 NCBI chr 4:50,452,857...50,456,015
Ensembl chr 4:56,286,708...56,288,083
JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 ISO protein:increased expression:synovial fluid, neutrophil RGD PMID:19017998 RGD:4145632 NCBI chr  X:60,880,759...60,883,355
Ensembl chr  X:70,933,160...70,935,756
JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr2B:23,744,271...23,748,106
Ensembl chr2B:140,181,829...140,189,647
JBrowse link
G DDIT4 DNA damage inducible transcript 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr10:68,796,712...68,798,840
Ensembl chr10:71,264,029...71,266,149
JBrowse link
G DDX6 DEAD-box helicase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr11:113,587,220...113,630,995
Ensembl chr11:117,515,778...117,559,364
JBrowse link
G DHFR dihydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr 5:34,663,210...34,689,467
Ensembl chr 5:34,938,548...34,967,003
JBrowse link
G DNASE1L3 deoxyribonuclease 1 like 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596, PMID:30224649 NCBI chr 3:58,127,491...58,146,177
Ensembl chr 3:59,542,243...59,560,363
JBrowse link
G DNMT1 DNA methyltransferase 1 severity ISO mRNA:increased expression:mononuclear cell RGD PMID:20937307 RGD:9588623 NCBI chr19:9,681,847...9,745,334
Ensembl chr19:10,342,478...10,406,972
JBrowse link
G DNMT3B DNA methyltransferase 3 beta disease_progression ISO DNA:polymorphism:promoter:-283C>T(human) RGD PMID:19777235 RGD:9589110 NCBI chr20:29,049,993...29,096,957
Ensembl chr20:30,186,069...30,215,487
JBrowse link
G EDN1 endothelin 1 treatment ISO RGD PMID:22249931 RGD:8661695 NCBI chr 6:12,076,312...12,142,861
Ensembl chr 6:12,462,718...12,503,545
JBrowse link
G ELN elastin ISO RGD PMID:12643515 RGD:9585739
G ENO1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19898480 NCBI chr 1:7,619,490...7,637,558
Ensembl chr 1:8,855,074...8,873,215
JBrowse link
G EPAS1 endothelial PAS domain protein 1 ISO protein:increased expression:layer of synovial tissue, stromal cell RGD PMID:12823854 RGD:10395366 NCBI chr2A:46,403,411...46,492,734
Ensembl chr2A:47,332,308...47,421,560
JBrowse link
G ESR2 estrogen receptor 2 severity ISO DNA:SNP:exon:rs1256049(human) RGD PMID:21523342 RGD:5508794 NCBI chr14:44,807,875...44,919,780
Ensembl chr14:63,064,402...63,131,303
JBrowse link
G F2 coagulation factor II, thrombin ISO CTD Direct Evidence: marker/mechanism CTD PMID:26001728 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157
JBrowse link
G FAS Fas cell surface death receptor susceptibility ISO protein:increased expression:serum (human)
DNA:snp:promoter:g.-670A>G (human)
RGD PMID:12148596, PMID:20875116, PMID:23053964 RGD:12903969, RGD:8662433, RGD:8662455 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612
JBrowse link
G FASLG Fas ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr 1:148,159,826...148,167,785
Ensembl chr 1:151,868,430...151,876,281
JBrowse link
G FCGR1A Fc fragment of IgG receptor Ia ISO protein:increased expression:synovial joint: RGD PMID:16670289 RGD:9685708 NCBI chr 1:125,127,073...125,136,911
Ensembl chr 1:128,805,484...128,814,220
JBrowse link
G FCGR2A Fc fragment of IgG receptor IIa ISO DNA:polymorphism: :p.H131R (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:8254199, PMID:12508778, PMID:20453842, PMID:23143596 RGD:5147978, RGD:5147984 NCBI chr 1:136,892,311...136,906,450 JBrowse link
G FKBP5 FKBP prolyl isomerase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 6:35,135,745...35,250,860
Ensembl chr 6:36,337,883...36,452,664
JBrowse link
G FOXO3 forkhead box O3 ISO mRNA,protein:increased expression:peripheral blood mononuclear cell, polymorphonuclear cell,synovium: RGD PMID:19435720 RGD:10402186 NCBI chr 6:106,360,519...106,485,676
Ensembl chr 6:110,406,266...110,516,272
JBrowse link
G FOXP3 forkhead box P3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20476861 NCBI chr  X:41,550,462...41,567,492
Ensembl chr  X:49,402,652...49,417,029
JBrowse link
G FPGS folylpolyglutamate synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr 9:98,921,986...98,933,542
Ensembl chr 9:127,593,592...127,604,200
JBrowse link
G GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr21:19,871,656...19,909,893
Ensembl chr21:33,244,457...33,282,331
JBrowse link
G GATA3 GATA binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr10:8,075,951...8,105,573
Ensembl chr10:8,064,207...8,086,272
JBrowse link
G GC GC vitamin D binding protein ISO CTD Direct Evidence: marker/mechanism
protein:decreased expression:plasma
CTD
RGD
PMID:3874814, PMID:9548303 RGD:5509931 NCBI chr 4:52,431,196...52,473,762
Ensembl chr 4:58,729,236...58,792,073
JBrowse link
G GDF5 growth differentiation factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18830904 NCBI chr20:31,761,199...31,766,229
Ensembl chr20:32,882,094...32,886,899
JBrowse link
G GGH gamma-glutamyl hydrolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr 8:59,547,821...59,571,523
Ensembl chr 8:61,222,194...61,246,252
JBrowse link
G GIN1 gypsy retrotransposon integrase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 5:98,440,271...98,475,300
Ensembl chr 5:104,124,849...104,175,826
JBrowse link
G GPRC5A G protein-coupled receptor class C group 5 member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr12:12,905,682...12,928,596
Ensembl chr12:13,282,865...13,305,727
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO protein: decreased expression: mononuclear leukocytes
DNA: deletion: : heterozygous
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:10094932, PMID:18662895 RGD:5688373, RGD:5688380 NCBI chr11:62,624,647...62,644,846
Ensembl chr11:65,939,164...65,959,066
JBrowse link
G GRK5 G protein-coupled receptor kinase 5 no_association ISO protein: : mononuclear blood cells
DNA: deletion::GRK2 and GRK6 deletions resulted in more severe arthritis
RGD PMID:10094932, PMID:18662895 RGD:5688373, RGD:5688380 NCBI chr10:115,776,236...116,026,221
Ensembl chr10:119,200,688...119,450,809
JBrowse link
G GRK6 G protein-coupled receptor kinase 6 ISO protein: decreased expression: mononuclear leukocytes
DNA: deletion: : homozygous
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:10094932, PMID:18662895 RGD:5688373, RGD:5688380 NCBI chr 5:172,704,978...172,744,907
Ensembl chr 5:179,790,662...179,807,410
JBrowse link
G GSDME gasdermin E ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr 7:25,373,485...25,433,001
Ensembl chr 7:24,977,838...25,039,525
JBrowse link
G GSTM1 glutathione S-transferase mu 1 susceptibility ISO DNA:deletion: :
DNA:deletion: :
RGD PMID:15940757, PMID:16870093, PMID:16887863 RGD:5490993, RGD:5490994, RGD:5490998 Ensembl chr 1:127,979,238...128,010,411 JBrowse link
G HAPLN1 hyaluronan and proteoglycan link protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 5:31,560,282...31,643,138
Ensembl chr 5:31,879,276...31,964,562
JBrowse link
G HCLS1 hematopoietic cell-specific Lyn substrate 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 3:118,733,505...118,763,177
Ensembl chr 3:125,642,973...125,669,095
JBrowse link
G HDAC1 histone deacetylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32289289 NCBI chr 1:31,578,373...31,619,970
Ensembl chr 1:32,585,791...32,626,410
JBrowse link
G HFE homeostatic iron regulator ISO DNA:missense mutation: :p.C282Y (rs1800562) (human) RGD PMID:30651232 RGD:14746965 NCBI chr 6:25,921,663...25,930,852
Ensembl chr 6:26,580,358...26,588,591
JBrowse link
G HGF hepatocyte growth factor disease_progression ISO protein:increased expression:serum: RGD PMID:24387171 RGD:8548659 NCBI chr 7:73,667,618...73,738,960
Ensembl chr 7:87,327,798...87,397,811
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO protein:increased expression:layer of synovial tissue, stromal cell RGD PMID:12823854 RGD:10395366 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885
JBrowse link
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 severity ISO RGD PMID:18025202 RGD:9685481 NCBI chr 7:26,835,881...26,846,578
Ensembl chr 7:26,439,443...26,449,985
JBrowse link
G HOXD10 homeobox D10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr2B:63,395,636...63,399,704
Ensembl chr2B:181,104,876...181,110,963
JBrowse link
G HOXD11 homeobox D11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr2B:63,386,806...63,398,777 JBrowse link
G HOXD13 homeobox D13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr2B:63,372,517...63,375,731 JBrowse link
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 1:185,262,599...185,311,417
Ensembl chr 1:190,086,449...190,116,765
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 ISO mRNA:increased expression:peripheral blood leukocyte: RGD PMID:21417552 RGD:10402843 NCBI chr14:82,700,881...82,707,020
Ensembl chr14:102,519,699...102,576,723
JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 ISO protein:increased expression:peripheral blood lymphocyte (human) RGD PMID:22047640 RGD:5688784 NCBI chr 5:128,463,186...128,517,563
Ensembl chr 5:134,619,076...134,673,658
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO protein:increased expression:synovial joint RGD PMID:11315915 RGD:5685639 NCBI chr 9:96,351,645...96,356,761
Ensembl chr 9:124,865,211...124,870,458
JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 ISO protein:increased expression:synovial cell: RGD PMID:23739258 RGD:10402561 NCBI chr 5:133,934,859...133,955,048
Ensembl chr 5:140,064,207...140,084,551
JBrowse link
G HSPB1 heat shock protein family B (small) member 1 ISO protein:increased expression:serum: RGD PMID:21417552 RGD:10402843 NCBI chr 7:67,716,021...67,717,762
Ensembl chr 7:82,751,523...82,752,984
JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 ISO mRNA:increased expression:peripheral blood leukocyte: RGD PMID:21417552 RGD:10402843 NCBI chr2B:84,729,615...84,743,352
Ensembl chr2B:202,623,497...202,636,959
JBrowse link
G IFNG interferon gamma treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:1417133, PMID:22450443 RGD:8157623 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829
JBrowse link
G IGF2 insulin like growth factor 2 ISO DNA:loss of imprinting:synovial cell
protein:decreased expression:plasma
RGD PMID:11247331, PMID:19556211 RGD:5510001, RGD:5510014 NCBI chr11:2,170,190...2,199,442
Ensembl chr11:2,202,743...2,228,890
JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr 7:46,564,234...46,573,145 JBrowse link
G IL10 interleukin 10 susceptibility ISO ClinVar Annotator: match by term: Rheumatoid arthritis, progression of
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:12847677, PMID:22450443 NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371
JBrowse link
G IL13 interleukin 13 ISO protein:increased expression:serum RGD PMID:12051401 RGD:8549582 NCBI chr 5:128,073,863...128,078,453
Ensembl chr 5:134,235,788...134,240,548
JBrowse link
G IL17A interleukin 17A treatment ISO RGD PMID:20926833 RGD:9068415 NCBI chr 6:51,736,269...51,740,538
Ensembl chr 6:53,004,820...53,009,074
JBrowse link
G IL18 interleukin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16368150 NCBI chr11:107,024,376...107,045,194
Ensembl chr11:110,867,586...110,888,371
JBrowse link
G IL19 interleukin 19 ISO ClinVar Annotator: match by term: Rheumatoid arthritis, progression of ClinVar PMID:12847677 NCBI chr 1:182,372,339...182,446,147
Ensembl chr 1:186,651,640...186,724,748
JBrowse link
G IL1A interleukin 1 alpha severity ISO protein:increased expression:plasma, synovial fluid
associated with lung disease, interstitial
RGD PMID:8162643, PMID:11192540 RGD:4142818, RGD:7794716 NCBI chr2A:89,273,482...89,284,421
Ensembl chr2A:113,784,854...113,795,801
JBrowse link
G IL1B interleukin 1 beta ISO protein:decreased expression:serum
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:12566094, PMID:17379860, PMID:22414257, PMID:22450443 RGD:6482656 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G IL2 interleukin 2 ISO RGD PMID:6421522 RGD:8662948 NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984
JBrowse link
G IL20 interleukin 20 ISO RGD PMID:16947773 RGD:5147395 NCBI chr 1:182,468,571...182,472,440
Ensembl chr 1:186,747,086...186,750,952
JBrowse link
G IL21R interleukin 21 receptor ISO RGD PMID:19342640 RGD:6892964 Ensembl chr16:27,774,864...27,821,769 JBrowse link
G IL23A interleukin 23 subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr12:32,575,321...32,576,856
Ensembl chr12:32,828,902...32,830,617
JBrowse link
G IL23R interleukin 23 receptor susceptibility ISO DNA:SNP::rs1343151(human) RGD PMID:18647855 RGD:8549596 NCBI chr 1:66,408,839...66,502,535
Ensembl chr 1:68,293,514...68,386,815
JBrowse link
G IL2RA interleukin 2 receptor subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842, PMID:20476861, PMID:23143596 NCBI chr10:6,053,549...6,103,863 JBrowse link
G IL2RB interleukin 2 receptor subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842, PMID:23143596 NCBI chr22:18,039,469...18,069,952
Ensembl chr22:35,874,898...35,899,038
JBrowse link
G IL3 interleukin 3 ISO DNA: SNPs: Multiple: gene-gene interaction RGD PMID:20018070 RGD:5686905 NCBI chr 5:127,483,843...127,486,388
Ensembl chr 5:133,647,667...133,650,213
JBrowse link
G IL4R interleukin 4 receptor severity ISO DNA:SNP: :rs1805010 (human) RGD PMID:24782180 RGD:10402783 Ensembl chr16:27,642,702...27,737,445 JBrowse link
G IL5 interleukin 5 ISO RGD PMID:22293286 RGD:5687156 NCBI chr 5:127,955,377...127,961,726
Ensembl chr 5:134,119,608...134,121,675
JBrowse link
G IL6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274, PMID:22450443 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G IL6R interleukin 6 receptor ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16729287, PMID:23143596 NCBI chr 1:129,761,914...129,824,386
Ensembl chr 1:133,374,078...133,433,089
JBrowse link
G IL6ST interleukin 6 signal transducer ISO CTD Direct Evidence: marker/mechanism CTD PMID:20453842 NCBI chr 5:58,023,704...58,081,895
Ensembl chr 5:59,669,606...59,708,817
JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr  X:143,560,802...143,570,185
Ensembl chr  X:153,446,827...153,460,602
JBrowse link
G IRF5 interferon regulatory factor 5 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Rheumatoid arthritis
CTD
ClinVar
PMID:15657875, PMID:16642019, PMID:17599733, PMID:18063667, PMID:20453842, PMID:23143596 NCBI chr 7:120,889,752...120,902,096
Ensembl chr 7:133,415,170...133,426,356
JBrowse link
G IRF8 interferon regulatory factor 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr16:66,568,370...66,591,949
Ensembl chr16:85,905,334...85,929,073
JBrowse link
G ITGA6 integrin subunit alpha 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr2B:59,714,348...59,794,762
Ensembl chr2B:177,169,536...177,250,143
JBrowse link
G ITGB2 integrin subunit beta 2 ISO ClinVar Annotator: match by term: Rheumatoid arthritis ClinVar PMID:30311386 NCBI chr21:31,181,228...31,216,033
Ensembl chr21:44,470,999...44,505,963
JBrowse link
G ITPA inosine triphosphatase treatment ISO DNA:SNP: :94C>A(human) RGD PMID:29441893 RGD:14975307 NCBI chr20:3,295,075...3,309,546
Ensembl chr20:3,056,395...3,070,924
JBrowse link
G JAK2 Janus kinase 2 ISO RGD PMID:21510883 RGD:6483024 NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626
JBrowse link
G KIF5A kinesin family member 5A susceptibility ISO DNA:snps:intron, 3' utr:c.2756-43A>C, c.*776C>T (rs775246, rs775251) (human)
CTD Direct Evidence: marker/mechanism
DNA:snp:intron:c.1717-152C>G (rs1678542) (human)
RGD
CTD
PMID:21784728, PMID:23143596, PMID:23378462 RGD:12793072, RGD:12793073 NCBI chr12:31,340,201...31,376,849
Ensembl chr12:31,599,376...31,635,327
JBrowse link
G LCN2 lipocalin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7554268 NCBI chr 9:99,259,278...99,274,494
Ensembl chr 9:127,940,799...127,944,798
JBrowse link
G LHX2 LIM homeobox 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 9:95,132,445...95,154,130
Ensembl chr 9:123,655,845...123,676,796
JBrowse link
G LOC100972994 HLA class II histocompatibility antigen, DQ beta 1 chain ISO DNA:polymorphism (human) RGD PMID:11454644 RGD:5147860 NCBI chr 6:32,237,395...32,244,201
Ensembl chr 6:33,353,599...33,360,272
JBrowse link
G LOC100973583 HLA class II histocompatibility antigen, DQ alpha 2 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 6:32,314,091...32,319,909
Ensembl chr 6:33,429,832...33,435,363
JBrowse link
G LOC100975642 zinc finger protein Aiolos ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr17:17,459,438...17,498,452
Ensembl chr17:17,643,750...17,741,479
JBrowse link
G LOC100991079 interleukin-1 receptor antagonist protein ISO CTD Direct Evidence: marker/mechanism|therapeutic RGD
CTD
PMID:7706905, PMID:10637275, PMID:19192274, PMID:19447938 RGD:7174696, RGD:8549810 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839
JBrowse link
G LOC100995226 HLA class II histocompatibility antigen, DP beta 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:17956852, PMID:22286218 NCBI chr 6:32,648,780...32,659,613
Ensembl chr 6:33,763,566...33,774,387
JBrowse link
G LRRK2 leucine rich repeat kinase 2 ISO RGD PMID:17082220 RGD:5508419 NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462
JBrowse link
G LY96 lymphocyte antigen 96 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr 8:70,525,058...70,567,839
Ensembl chr 8:72,169,986...72,207,372
JBrowse link
G MAB21L2 mab-21 like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 4:142,913,376...142,916,001
Ensembl chr 4:154,563,939...154,565,018
JBrowse link
G MARCKS myristoylated alanine rich protein kinase C substrate ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 6:111,647,847...111,653,821 JBrowse link
G MBD2 methyl-CpG binding domain protein 2 ISO mRNA:increased expression:mononuclear cell RGD PMID:20937307 RGD:9588623 NCBI chr18:47,534,356...47,609,481 JBrowse link
G MBD4 methyl-CpG binding domain 4, DNA glycosylase susceptibility
no_association
ISO DNA:snps:introns:IVS5-140A>G (rs3138355), IVS6-218C>T (rs2005618) (human)
DNA:snps:cds, intron:p.E346K, IVS6-218C>T (rs140693, rs2005618) (human)
RGD PMID:20676650, PMID:22505706 RGD:9588977, RGD:9588978 NCBI chr 3:126,489,125...126,498,034
Ensembl chr 3:133,839,643...133,851,450
JBrowse link
G MDK midkine ISO RGD PMID:15146411 RGD:1581200 NCBI chr11:46,339,365...46,342,388
Ensembl chr11:46,891,540...46,893,254
JBrowse link
G MGARP mitochondria localized glutamic acid rich protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 4:131,629,272...131,643,996
Ensembl chr 4:142,936,873...142,952,601
JBrowse link
G MIF macrophage migration inhibitory factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16872482 NCBI chr22:4,646,986...4,647,831
Ensembl chr22:22,730,807...22,732,009
JBrowse link
G MMEL1 membrane metalloendopeptidase like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 1:1,323,914...1,362,178
Ensembl chr 1:2,462,621...2,504,213
JBrowse link
G MMP1 matrix metallopeptidase 1 ISO protein:increased expression:plasma (human) RGD PMID:9972954 RGD:7207129 NCBI chr11:97,730,545...97,739,190
Ensembl chr11:101,221,393...101,230,104
JBrowse link
G MMP10 matrix metallopeptidase 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr11:97,710,819...97,721,263
Ensembl chr11:101,201,665...101,212,103
JBrowse link
G MMP12 matrix metallopeptidase 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr11:97,809,644...97,822,063
Ensembl chr11:101,294,475...101,306,762
JBrowse link
G MMP2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16872482 NCBI chr16:35,711,866...35,738,881
Ensembl chr16:54,812,694...54,844,279
JBrowse link
G MMP3 matrix metallopeptidase 3 disease_progression ISO protein:increased expression:serum (human) RGD PMID:7639798, PMID:11796404, PMID:22314025 RGD:7207128, RGD:7241254, RGD:8693673 NCBI chr11:97,776,729...97,784,549
Ensembl chr11:101,267,566...101,275,354
JBrowse link
G MMP8 matrix metallopeptidase 8 ISO protein:increased expression:synovial fluid, serum (human) RGD PMID:15194590 RGD:7207131 NCBI chr11:97,650,408...97,663,731
Ensembl chr11:101,143,268...101,156,736
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO RGD PMID:16406300 RGD:1582623 NCBI chr20:42,346,305...42,354,018
Ensembl chr20:43,432,389...43,440,129
JBrowse link
G MPO myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22450443, PMID:26001728 NCBI chr17:52,333,882...52,357,838
Ensembl chr17:57,201,073...57,212,111
JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO DNA:SNP: :677C>T(human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:22104130, PMID:23685257 RGD:7387222 NCBI chr 1:10,548,196...10,568,174
Ensembl chr 1:11,766,334...11,785,419
JBrowse link
G NCF1 neutrophil cytosolic factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524, PMID:28135245 Ensembl chr 7:81,917,167...81,932,589 JBrowse link
G NCF2 neutrophil cytosolic factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 1:159,085,923...159,121,259
Ensembl chr 1:163,243,636...163,278,420
JBrowse link
G NDUFA4L2 NDUFA4 mitochondrial complex associated like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr12:31,686,325...31,692,483
Ensembl chr12:31,940,681...31,944,813
JBrowse link
G NFKBIE NFKB inhibitor epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr 6:43,853,921...43,861,686
Ensembl chr 6:45,138,209...45,144,680
JBrowse link
G NFKBIL1 NFKB inhibitor like 1 susceptibility ISO ClinVar Annotator: match by term: Rheumatoid arthritis
CTD Direct Evidence: marker/mechanism
DNA:snp:promoter:c.-132T>A (rs2071592) (human)
OMIM
ClinVar
CTD
RGD
PMID:12509789 RGD:1331681 NCBI chr 6:31,207,927...31,219,916
Ensembl chr 6:32,098,554...32,109,944
JBrowse link
G NOTCH4 notch receptor 4 ISO mRNA : increased expression: : cd4+ cells RGD PMID:20132067 RGD:6480790 NCBI chr 6:31,842,233...31,871,412
Ensembl chr 6:32,722,112...32,750,978
JBrowse link
G NPSR1 neuropeptide S receptor 1 ISO RGD PMID:20179762 RGD:4891930 NCBI chr 7:35,274,102...35,494,389
Ensembl chr 7:35,663,335...35,883,988
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO mRNA:increased expression:paw RGD PMID:18448865 RGD:4892311 NCBI chr 5:138,634,278...139,089,171
Ensembl chr 5:144,741,452...144,865,269
JBrowse link
G NR4A3 nuclear receptor subfamily 4 group A member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 9:70,907,056...70,950,221 JBrowse link
G PADI2 peptidyl arginine deiminase 2 ISO ClinVar Annotator: match by term: Rheumatoid arthritis ClinVar NCBI chr 1:16,011,708...16,064,344
Ensembl chr 1:17,067,729...17,120,513
JBrowse link
G PADI4 peptidyl arginine deiminase 4 susceptibility ISO ClinVar Annotator: match by term: Rheumatoid arthritis
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:23143596 NCBI chr 1:16,255,680...16,311,256
Ensembl chr 1:17,311,436...17,365,426
JBrowse link
G PDGFB platelet derived growth factor subunit B ISO RGD PMID:1708827 RGD:6482653 NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883
JBrowse link
G PGF placental growth factor ISO RGD PMID:19180491 RGD:6483591 NCBI chr14:55,494,152...55,508,066 JBrowse link
G PLA2G7 phospholipase A2 group VII ISO RGD PMID:17326817 RGD:6482776 NCBI chr 6:46,264,262...46,318,487
Ensembl chr 6:47,558,861...47,590,212
JBrowse link
G PLAUR plasminogen activator, urokinase receptor ISO RGD PMID:22011479 RGD:6484117 NCBI chr19:40,588,100...40,616,479
Ensembl chr19:49,197,341...49,222,561
Ensembl chr19:49,197,341...49,222,561
JBrowse link
G PLB1 phospholipase B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24520335 NCBI chr2A:28,502,449...28,650,348
Ensembl chr2A:28,584,636...28,730,640
JBrowse link
G PLD4 phospholipase D family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr14:85,574,724...85,587,176
Ensembl chr14:105,360,584...105,369,247
JBrowse link