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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:rheumatic disease
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Accession:DOID:1575 term browser browse the term
Definition:Disorders of connective tissue, especially the joints and related structures, characterized by inflammation, degeneration, or metabolic derangement.
Synonyms:exact_synonym: rheumatic diseases;   rheumatism
 primary_id: MESH:D012216
For additional species annotation, visit the Alliance of Genome Resources.


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adult-onset Still's disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HGF hepatocyte growth factor IEP protein:increased expression:serum: RGD PMID:24387171 RGD:8548659 NCBI chr 7:81,699,006...81,770,438
Ensembl chr 7:81,699,010...81,770,438
JBrowse link
G VEGFA vascular endothelial growth factor A IEP protein:increased expression:serum: RGD PMID:24387171 RGD:8548659 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
Beukes hip dysplasia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4orf47 chromosome 4 open reading frame 47 IAGP ClinVar Annotator: match by term: Hip dysplasia, beukes type ClinVar PMID:2389793, PMID:21228277, PMID:26428751 NCBI chr 4:185,405,227...185,449,828
Ensembl chr 4:185,426,249...185,449,826
JBrowse link
G UFSP2 UFM1 specific peptidase 2 IAGP ClinVar Annotator: match by term: OSTEOARTHROPATHY, PREMATURE DEGENERATIVE, OF HIP
ClinVar Annotator: match by term: Hip dysplasia, beukes type
OMIM
ClinVar
PMID:2389793, PMID:21228277, PMID:25741868, PMID:26428751, PMID:28892125 NCBI chr 4:185,399,537...185,425,964
Ensembl chr 4:185,399,537...185,425,979
JBrowse link
CREST syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CENPC centromere protein C IDA associated with Anticentromere antibody positivity RGD PMID:25220385 RGD:27372886 NCBI chr 4:67,468,762...67,545,503
Ensembl chr 4:67,468,762...67,545,503
JBrowse link
G FBN1 fibrillin 1 IDA RGD PMID:10395706 RGD:12910471 NCBI chr15:48,408,313...48,645,709
Ensembl chr15:48,408,306...48,645,849
Ensembl chr15:48,408,306...48,645,849
JBrowse link
diffuse scleroderma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing severity IEP protein:decreased expression:serum RGD PMID:21615510 RGD:8694418 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
JBrowse link
G AGT angiotensinogen IEP protein:increased expression:serum RGD PMID:14730619 RGD:8548886 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,702,523...230,714,122
JBrowse link
G BANK1 B cell scaffold protein with ankyrin repeats 1 susceptibility IAGP DNA:SNPs: :rs10516487,rs17266594,rs3733197(human) RGD PMID:19815934 RGD:9684975 NCBI chr 4:101,790,482...102,074,812
Ensembl chr 4:101,411,286...102,074,812
JBrowse link
G CAV1 caveolin 1 susceptibility
no_association
IAGP DNA:SNPs:intron, 3' utr: (rs729949, rs3815412, rs9920) (human)
DNA:SNPs:enhancer, intron:multiple
RGD PMID:22402147, PMID:22402147 RGD:8661768, RGD:8661768 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,525,001...116,561,184
JBrowse link
G CXCL5 C-X-C motif chemokine ligand 5 IEP RGD PMID:18432520 RGD:5135258 NCBI chr 4:73,995,642...73,998,677
Ensembl chr 4:73,995,642...73,998,677
JBrowse link
G FCGR2A Fc fragment of IgG receptor IIa IDA RGD PMID:8254199 RGD:5147984 NCBI chr 1:161,505,430...161,524,048
Ensembl chr 1:161,505,430...161,524,013
JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 susceptibility IAGP DNA:polymorphism::HLA-DQA1*0501; RGD PMID:11014350 RGD:8547725 NCBI chr 6:32,637,406...32,654,846
Ensembl chr 6:32,628,179...32,647,062
JBrowse link
G IL10 interleukin 10 IEP protein:increased expression:serum RGD PMID:9034992 RGD:5684371 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL13 interleukin 13 IAGP DNA:SNPs:5' utr, enhancer: (rs1800925, rs2243204) (human) RGD PMID:16832637 RGD:5684369 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
JBrowse link
G IL6 interleukin 6 treatment IEP RGD PMID:20338043 RGD:12792275 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 susceptibility IAGP DNA:missense mutation:cds:p.F196S (rs1059702) (human) RGD PMID:21898345 RGD:7495782 NCBI chr  X:154,010,507...154,019,984
Ensembl chr  X:154,010,506...154,019,902
JBrowse link
G KDR kinase insert domain receptor IEP protein:increased expression:serum: RGD PMID:19886888 RGD:8551850 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595
JBrowse link
G STAT4 signal transducer and activator of transcription 4 susceptibility
no_association
IAGP DNA:SNP:introns: (rs7574865, rs10168266) (human)
DNA:SNP:intron: (rs7574865) (human)
DNA:SNP:intron: (rs3821236) (human)
RGD PMID:23755762, PMID:19286670, PMID:23755762 RGD:8661701, RGD:8661714, RGD:8661701 NCBI chr 2:191,029,576...191,172,684
Ensembl chr 2:191,029,576...191,151,596
JBrowse link
G TAP1 transporter 1, ATP binding cassette subfamily B member susceptibility IAGP RGD PMID:16112028 RGD:1578361 NCBI chr 6:32,845,209...32,853,704
Ensembl chr 6:32,845,209...32,853,978
JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member susceptibility IAGP RGD PMID:16112028 RGD:1578361 NCBI chr 6:32,821,831...32,838,739
Ensembl chr 6:32,821,833...32,838,770
JBrowse link
G TLR2 toll like receptor 2 disease_progression IAGP DNA:polymorphism:cds:p.P631H(rs5743704)(human) RGD PMID:21905008 RGD:8553044 NCBI chr 4:153,684,080...153,710,643
Ensembl chr 4:153,684,070...153,706,260
Ensembl chr 4:153,684,070...153,706,260
JBrowse link
G WRN WRN RecQ like helicase IDA RGD PMID:16906373 RGD:10042980 NCBI chr 8:31,033,749...31,176,138
Ensembl chr 8:31,033,788...31,176,138
Ensembl chr 8:31,033,788...31,176,138
JBrowse link
Digital Arthropathy-Brachydactyly, Familial term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRPV4 transient receptor potential cation channel subfamily V member 4 IAGP ClinVar Annotator: match by term: Digital arthropathy-brachydactyly, familial ClinVar
OMIM
PMID:956253, PMID:1520078, PMID:4056805, PMID:8179305, PMID:11891693, PMID:14755468, PMID:18587396, PMID:19232556, PMID:20037586, PMID:20037587, PMID:20037588, PMID:20104247, PMID:20425821, PMID:20460441, PMID:20503319, PMID:20577006, PMID:21115951, PMID:21288981, PMID:21336783, PMID:21454511, PMID:21964574, PMID:22702953, PMID:22791502, PMID:22851605, PMID:24575025, PMID:24677493, PMID:24789864, PMID:25256292, PMID:25741868, PMID:25900305, PMID:26110311, PMID:26249260, PMID:26467025, PMID:27330106, PMID:28492532, PMID:28898540 NCBI chr12:109,783,087...109,833,398
Ensembl chr12:109,783,087...109,833,406
Ensembl chr12:109,783,087...109,833,406
JBrowse link
erythema nodosum term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 IEP associated with Leprosy RGD PMID:2783924 RGD:7421527 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G CFB complement factor B IEP associated with Leprosy RGD PMID:2783924 RGD:7421527 NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,084
JBrowse link
G GSTM1 glutathione S-transferase mu 1 susceptibility IAGP associated with Behcet Syndrome;DNA:deletion:: (human) RGD PMID:22766250 RGD:7794848 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G HLA-B major histocompatibility complex, class I, B IAGP associated with Inflammatory Bowel Diseases; DNA:polymorphisms:cds:multiple (human) RGD PMID:12198697 RGD:7364926 NCBI chr 6:31,353,875...31,357,179
Ensembl chr 6:31,269,491...31,357,188
JBrowse link
G LTA lymphotoxin alpha IAGP associated with Sarcoidosis;DNA:polymorphism:intron RGD PMID:19225544 RGD:8548773 NCBI chr 6:31,560,550...31,574,324
Ensembl chr 6:31,572,054...31,574,324
JBrowse link
G TNF tumor necrosis factor susceptibility IAGP associated with Inflammatory Bowel Diseases;DNA:polymorphisms: :-1031T>C(human) RGD PMID:12198697 RGD:7364926 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G VDR vitamin D receptor susceptibility IAGP associated with Behcet Syndrome;DNA:polymorphism: : rs7975232(human) RGD PMID:24880677 RGD:13217417 NCBI chr12:47,841,537...47,905,022
Ensembl chr12:47,841,537...47,943,048
JBrowse link
Familial Osteochondritis Dissecans term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAN aggrecan IAGP OMIM NCBI chr15:88,803,436...88,875,353
Ensembl chr15:88,803,436...88,875,354
Ensembl chr15:88,803,436...88,875,354
JBrowse link
fibromyalgia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAT catalase IEP protein:decreased activity:mononuclear cell: RGD PMID:22532869 RGD:9479066 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCL2 C-C motif chemokine ligand 2 IEP protein:decreased expression:plasma RGD PMID:19924498 RGD:14995946 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,218...34,257,203
JBrowse link
G COMT catechol-O-methyltransferase severity IAGP DNA:polymorphism:cds:p.V158M(human) RGD PMID:24762091 RGD:13450944 NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,733...19,969,975
Ensembl chr22:19,941,733...19,969,975
JBrowse link
G IL1RN interleukin 1 receptor antagonist severity IEP protein:increased expression:serum (human) RGD PMID:10341365 RGD:8549787 NCBI chr 2:113,099,365...113,134,016
Ensembl chr 2:113,107,214...113,134,016
JBrowse link
Hand Osteoarthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC079145.1 novel transcript IAGP ClinVar Annotator: match by term: HAND OSTEOARTHRITIS ClinVar PMID:12736871 NCBI chr 2:19,990,204...20,004,806
Ensembl chr 2:19,990,209...20,004,795
JBrowse link
G ESR1 estrogen receptor 1 no_association IAGP DNA:SNPs:exons: (rs2077647, rs1801132) (human) RGD PMID:19884274 RGD:10045830 NCBI chr 6:151,654,148...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G ESR2 estrogen receptor 2 no_association IAGP DNA:SNPs:introns: (rs1256034, rs1256059, rs944460) (human) RGD PMID:19884274 RGD:10045830 NCBI chr14:64,226,707...64,338,631
Ensembl chr14:64,084,232...64,338,112
JBrowse link
G IL4 interleukin 4 no_association IAGP DNA:SNPs:promoter, 5' utr, intron:multiple RGD PMID:20219689 RGD:10402786 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G IL4R interleukin 4 receptor no_association IAGP DNA:SNPs:promoter, exons:multiple RGD PMID:20219689 RGD:10402786 NCBI chr16:27,313,668...27,364,778
Ensembl chr16:27,313,668...27,364,778
JBrowse link
G MATN3 matrilin 3 IAGP ClinVar Annotator: match by term: HAND OSTEOARTHRITIS ClinVar PMID:12736871 NCBI chr 2:19,992,052...20,012,668
Ensembl chr 2:19,992,052...20,012,668
JBrowse link
Juvenile Pauciarticular Chronic Arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 susceptibility IAGP DNA:polymorphism: :HLA-DRB1*1104, HLA-DRB1*080(human) RGD PMID:7955632 RGD:7365102 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,578,769...32,589,848
JBrowse link
juvenile rheumatoid arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP3 acid phosphatase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:132,317,403...132,368,765
Ensembl chr 3:132,317,369...132,368,298
JBrowse link
G ACRBP acrosin binding protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:6,638,075...6,647,432
Ensembl chr12:6,638,075...6,647,433
JBrowse link
G ADCY7 adenylate cyclase 7 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr16:50,246,138...50,318,135
Ensembl chr16:50,246,137...50,318,135
JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:6,993,791...7,010,754
Ensembl chr17:6,996,049...7,010,754
JBrowse link
G ANKRD9 ankyrin repeat domain 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:102,501,767...102,509,776
Ensembl chr14:102,501,767...102,509,799
JBrowse link
G AOPEP aminopeptidase O (putative) EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:94,726,669...95,148,264
Ensembl chr 9:94,726,701...95,087,218
JBrowse link
G APOBEC3A apolipoprotein B mRNA editing enzyme catalytic subunit 3A EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr22:38,957,609...38,963,184
Ensembl chr22:38,952,741...38,992,778
JBrowse link
G AQP9 aquaporin 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:58,138,169...58,185,911
Ensembl chr15:58,138,169...58,185,911
JBrowse link
G AREG amphiregulin EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:74,445,136...74,455,005
Ensembl chr 4:74,445,136...74,455,005
JBrowse link
G ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:130,052,104...130,443,848
Ensembl chr 8:130,052,104...130,443,674
JBrowse link
G AVL9 AVL9 cell migration associated EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:32,495,489...32,588,726
Ensembl chr 7:32,495,426...32,588,726
JBrowse link
G B4GALT5 beta-1,4-galactosyltransferase 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr20:49,632,945...49,713,878
Ensembl chr20:49,632,945...49,713,878
JBrowse link
G BEND2 BEN domain containing 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr  X:18,162,931...18,220,886
Ensembl chr  X:18,162,931...18,220,886
JBrowse link
G BTG1 BTG anti-proliferation factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:92,140,278...92,145,846
Ensembl chr12:92,140,278...92,145,846
JBrowse link
G BTG3 BTG anti-proliferation factor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr21:17,593,653...17,612,940
Ensembl chr21:17,593,653...17,612,947
Ensembl chr21:17,593,653...17,612,947
JBrowse link
G C2orf88 chromosome 2 open reading frame 88 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:189,879,479...190,203,484
Ensembl chr 2:189,879,609...190,203,484
JBrowse link
G C8B complement C8 beta chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:7980680 NCBI chr 1:56,929,207...56,974,383
Ensembl chr 1:56,929,207...56,966,140
JBrowse link
G C9orf72 C9orf72-SMCR8 complex subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:27,546,546...27,573,866
Ensembl chr 9:27,535,640...27,573,866
JBrowse link
G CALD1 caldesmon 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:134,779,629...134,970,729
Ensembl chr 7:134,744,252...134,970,729
JBrowse link
G CAMSAP1 calmodulin regulated spectrin associated protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:135,808,487...135,907,551
Ensembl chr 9:135,808,487...135,907,546
JBrowse link
G CCR5 C-C motif chemokine receptor 5 no_association IAGP DNA:polymorphisms: :multiple (human)
DNA:frameshift mutation:cds:p.S185_T195del rs333 (human)
RGD PMID:16775617, PMID:17565662 RGD:1626284, RGD:1626283 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,854...46,376,206
JBrowse link
G CD14 CD14 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,701
JBrowse link
G CD83 CD83 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:14,117,256...14,136,918
Ensembl chr 6:14,117,256...14,136,918
JBrowse link
G CD8B CD8b molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:86,815,369...86,861,886
Ensembl chr 2:86,815,339...86,861,924
JBrowse link
G CIITA class II major histocompatibility complex transactivator susceptibility
no_association
IAGP DNA:polymorphism:exon:1614G>C (human)
DNA:polymorphism:promoter:rs3087456, no association in a German cohort
RGD PMID:17661914, PMID:16426246 RGD:5491187, RGD:5491189 NCBI chr16:10,866,208...10,941,562
Ensembl chr16:10,866,222...10,943,021
JBrowse link
G CLU clusterin EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700
JBrowse link
G CMTM2 CKLF like MARVEL transmembrane domain containing 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr16:66,579,463...66,588,275
Ensembl chr16:66,579,448...66,588,275
JBrowse link
G CREM cAMP responsive element modulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:35,126,830...35,212,958
Ensembl chr10:35,126,791...35,212,958
JBrowse link
G CRP C-reactive protein IEP protein:increased expression:serum RGD PMID:22885951 RGD:6906884 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,867,771...203,873,965
JBrowse link
G CTTN cortactin EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:70,398,529...70,436,579
Ensembl chr11:70,398,404...70,436,584
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:218,125,294...218,137,253
Ensembl chr 2:218,125,289...218,137,251
JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504, PMID:26387944 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,118,149
JBrowse link
G DAPK1 death associated protein kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:87,497,228...87,708,634
Ensembl chr 9:87,497,228...87,708,634
JBrowse link
G DDIT3 DNA damage inducible transcript 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G DUSP1 dual specificity phosphatase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195
JBrowse link
G DUSP2 dual specificity phosphatase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:96,143,166...96,145,468
Ensembl chr 2:96,143,169...96,145,440
JBrowse link
G DUSP4 dual specificity phosphatase 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:29,333,064...29,350,684
Ensembl chr 8:29,333,064...29,350,684
JBrowse link
G DYSF dysferlin EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:71,453,154...71,686,763
Ensembl chr 2:71,453,722...71,686,768
JBrowse link
G EGF epidermal growth factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
JBrowse link
G EGR1 early growth response 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G ELF2 E74 like ETS transcription factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:139,057,220...139,177,218
Ensembl chr 4:139,028,112...139,177,218
JBrowse link
G ETNK1 ethanolamine kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:22,625,145...22,690,665
Ensembl chr12:22,625,075...22,690,665
JBrowse link
G ETV6 ETS variant transcription factor 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:11,649,601...11,895,386
Ensembl chr12:11,649,674...11,895,377
Ensembl chr12:11,649,674...11,895,377
JBrowse link
G FAM20A FAM20A golgi associated secretory pathway pseudokinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:68,530,276...68,601,367
Ensembl chr17:68,535,113...68,601,367
JBrowse link
G FAXDC2 fatty acid hydroxylase domain containing 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:154,817,018...154,850,683
Ensembl chr 5:154,818,492...154,859,252
JBrowse link
G FCGR1A Fc fragment of IgG receptor Ia EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:149,782,694...149,800,609
Ensembl chr 1:149,782,671...149,792,518
JBrowse link
G FCHSD2 FCH and double SH3 domains 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:72,836,743...73,142,682
Ensembl chr11:72,836,745...73,142,318
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G FOSB FosB proto-oncogene, AP-1 transcription factor subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr19:45,467,996...45,475,179
Ensembl chr19:45,467,995...45,475,179
JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:28,392,855...28,417,317
Ensembl chr 2:28,392,448...28,417,317
JBrowse link
G FOXP1 forkhead box P1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:70,954,708...71,583,983
Ensembl chr 3:70,952,817...71,583,993
Ensembl chr 3:70,952,817...71,583,993
JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
JBrowse link
G GMPR guanosine monophosphate reductase EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:16,238,587...16,295,549
Ensembl chr 6:16,238,587...16,295,549
JBrowse link
G GNG11 G protein subunit gamma 11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:93,921,735...93,928,610
Ensembl chr 7:93,921,735...93,928,610
JBrowse link
G GP1BB glycoprotein Ib platelet subunit beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr22:19,723,539...19,724,771
Ensembl chr22:19,723,539...19,724,771
Ensembl chr22:19,723,539...19,724,771
JBrowse link
G GSTT1 glutathione S-transferase theta 1 susceptibility IAGP DNA:deletion: : RGD PMID:18328165 RGD:5490992
G H2AC8 H2A clustered histone 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:26,216,921...26,217,483
Ensembl chr 6:26,216,975...26,217,483
JBrowse link
G H2BC8 H2B clustered histone 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:26,216,200...26,216,688
Ensembl chr 6:26,215,159...26,216,692
JBrowse link
G HBEGF heparin binding EGF like growth factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:140,332,843...140,346,603
Ensembl chr 5:140,332,843...140,346,603
JBrowse link
G HERPUD2 HERPUD family member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:35,632,659...35,695,811
Ensembl chr 7:35,632,659...35,697,459
Ensembl chr 7:35,632,659...35,697,459
JBrowse link
G HFE homeostatic iron regulator IAGP DNA:missense mutation:cds:p.C282Y (human) RGD PMID:16047841 RGD:8694357 NCBI chr 6:26,087,347...26,098,343
Ensembl chr 6:26,087,281...26,098,343
JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 IEP
IAGP
DNA:polymorphism (human) RGD PMID:19811310, PMID:10457895 RGD:5147815, RGD:5147863 NCBI chr 6:32,637,406...32,654,846
Ensembl chr 6:32,628,179...32,647,062
JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 IAGP DNA:polymorphism (human) RGD PMID:10457895 RGD:5147863 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383
JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 IAGP DNA:polymorphism (human) RGD PMID:19908388, PMID:10457895 RGD:5147587, RGD:5147863 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,578,769...32,589,848
JBrowse link
G HSPA6 heat shock protein family A (Hsp70) member 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:161,524,540...161,526,894
Ensembl chr 1:161,524,540...161,526,894
JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 IEP protein:increased expression:serum,synovial fluid: RGD PMID:8255671 RGD:12910480 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737
JBrowse link
G IGF1R insulin like growth factor 1 receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530
JBrowse link
G IL1A interleukin 1 alpha IAGP DNA:SNP:promoter:-889C>T (human) RGD PMID:8162643 RGD:7794716 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1RN interleukin 1 receptor antagonist EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:113,099,365...113,134,016
Ensembl chr 2:113,107,214...113,134,016
JBrowse link
G IL2 interleukin 2 IEP protein:increased expression:mononuclear cell RGD PMID:21859687 RGD:5147870 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL6 interleukin 6 IEP
IEA
protein:increased expression:serum:
OMIM:604302
MouseDO PMID:9489833 RGD:7829742 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G ITGA2B integrin subunit alpha 2b EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:44,372,181...44,389,649
Ensembl chr17:44,372,180...44,389,649
JBrowse link
G ITGB5 integrin subunit beta 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:124,761,948...124,901,418
Ensembl chr 3:124,761,948...124,901,418
JBrowse link
G JMJD1C jumonji domain containing 1C EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:63,167,221...63,521,890
Ensembl chr10:63,167,221...63,521,850
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,780,791...58,784,047
JBrowse link
G KAT6B lysine acetyltransferase 6B EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:74,824,927...75,032,624
Ensembl chr10:74,824,927...75,032,624
JBrowse link
G KCNJ15 potassium inwardly rectifying channel subfamily J member 15 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr21:38,229,926...38,307,357
Ensembl chr21:38,155,549...38,307,357
JBrowse link
G KLF4 Kruppel like factor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:107,484,852...107,489,769
Ensembl chr 9:107,484,852...107,490,482
JBrowse link
G KRAS KRAS proto-oncogene, GTPase EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
JBrowse link
G LACC1 laccase domain containing 1 IAGP ClinVar Annotator: match by term: JUVENILE ARTHRITIS OMIM
ClinVar
PMID:25147203, PMID:25220867, PMID:27881174, PMID:29717096, PMID:30872671 NCBI chr13:43,879,178...43,893,932
Ensembl chr13:43,879,284...43,893,932
JBrowse link
G LILRA5 leukocyte immunoglobulin like receptor A5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr19:54,307,070...54,313,166
Ensembl chr19:54,307,070...54,313,166
JBrowse link
G LPP LIM domain containing preferred translocation partner in lipoma EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:188,152,152...188,890,671
Ensembl chr 3:188,153,284...188,890,671
JBrowse link
G MAD1L1 mitotic arrest deficient 1 like 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:1,815,795...2,232,945
Ensembl chr 7:1,815,793...2,233,243
JBrowse link
G MAFF MAF bZIP transcription factor F EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr22:38,201,994...38,216,511
Ensembl chr22:38,200,767...38,216,507
JBrowse link
G MAML2 mastermind like transcriptional coactivator 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:95,976,598...96,343,308
Ensembl chr11:95,976,598...96,343,195
JBrowse link
G MAP2 microtubule associated protein 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:209,424,047...209,734,118
Ensembl chr 2:209,424,058...209,734,118
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,754,500...21,867,680
Ensembl chr22:21,754,500...21,867,680
JBrowse link
G MBL2 mannose binding lectin 2 IEP RGD PMID:18334024 RGD:12910845 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784
JBrowse link
G MEX3C mex-3 RNA binding family member C EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr18:51,174,550...51,197,681
Ensembl chr18:51,174,550...51,218,333
Ensembl chr18:51,174,550...51,218,333
JBrowse link
G MIF macrophage migration inhibitory factor IEA OMIM:604302 MouseDO NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227
JBrowse link
G MIR22HG MIR22 host gene EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:1,711,504...1,716,272
Ensembl chr17:1,711,493...1,717,174
JBrowse link
G MS4A4A membrane spanning 4-domains A4A EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:60,280,666...60,308,970
Ensembl chr11:60,185,702...60,317,944
JBrowse link
G MSN moesin EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr  X:65,588,382...65,741,931
Ensembl chr  X:65,588,377...65,741,931
JBrowse link
G MTSS1 MTSS I-BAR domain containing 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:124,550,784...124,728,473
Ensembl chr 8:124,550,784...124,728,473
Ensembl chr 8:124,550,784...124,728,473
JBrowse link
G MYZAP myocardial zonula adherens protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:57,591,904...57,685,364
Ensembl chr15:57,591,904...57,685,364
JBrowse link
G NDEL1 nudE neurodevelopment protein 1 like 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:8,435,884...8,472,744
Ensembl chr17:8,413,131...8,490,411
JBrowse link
G NEAT1 nuclear paraspeckle assembly transcript 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:65,422,798...65,445,540
Ensembl chr11:65,422,774...65,445,540
JBrowse link
G NR4A2 nuclear receptor subfamily 4 group A member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:156,324,432...156,332,724
Ensembl chr 2:156,324,437...156,342,348
JBrowse link
G NR4A3 nuclear receptor subfamily 4 group A member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:99,821,885...99,866,893
Ensembl chr 9:99,821,855...99,866,891
JBrowse link
G NRG1 neuregulin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:31,639,245...32,774,046
Ensembl chr 8:31,639,222...32,855,666
JBrowse link
G OLR1 oxidized low density lipoprotein receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:10,158,301...10,172,132
Ensembl chr12:10,158,301...10,172,138
JBrowse link
G OSM oncostatin M EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr22:30,262,829...30,266,851
Ensembl chr22:30,262,829...30,266,851
JBrowse link
G PACSIN2 protein kinase C and casein kinase substrate in neurons 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr22:42,869,766...43,015,149
Ensembl chr22:42,835,412...43,015,149
JBrowse link
G PCYT1B phosphate cytidylyltransferase 1, choline, beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr  X:24,558,087...24,672,887
Ensembl chr  X:24,558,087...24,672,677
JBrowse link
G PER1 period circadian regulator 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:8,140,470...8,156,360
Ensembl chr17:8,140,472...8,156,506
JBrowse link
G PGM5 phosphoglucomutase 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 9:68,356,584...68,531,061
Ensembl chr 9:68,328,308...68,531,061
JBrowse link
G PLAUR plasminogen activator, urokinase receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr19:43,646,095...43,670,197
Ensembl chr19:43,646,095...43,670,547
JBrowse link
G PLK2 polo like kinase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:58,453,982...58,460,086
Ensembl chr 5:58,453,982...58,460,139
JBrowse link
G PLOD2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:146,069,437...146,161,184
Ensembl chr 3:146,069,440...146,163,653
JBrowse link
G PROS1 protein S EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:93,873,051...93,973,896
Ensembl chr 3:93,873,051...93,980,003
Ensembl chr 3:93,873,051...93,980,003
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 IAGP DNA: snp : cds : rs2476601 RGD PMID:15934099 RGD:6484550 NCBI chr 1:113,813,811...113,871,761
Ensembl chr 1:113,813,811...113,871,753
JBrowse link
G R3HDM2 R3H domain containing 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:57,253,764...57,431,043
Ensembl chr12:57,253,762...57,431,005
JBrowse link
G RASGEF1B RasGEF domain family member 1B EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:81,426,393...81,471,907
Ensembl chr 4:81,426,393...82,044,244
JBrowse link
G RBM47 RNA binding motif protein 47 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 4:40,423,270...40,630,911
Ensembl chr 4:40,423,267...40,630,875
JBrowse link
G RERE arginine-glutamic acid dipeptide repeats EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 1:8,352,404...8,817,640
Ensembl chr 1:8,352,397...8,848,921
JBrowse link
G RHOBTB1 Rho related BTB domain containing 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:60,869,438...61,001,486
Ensembl chr10:60,869,438...61,001,440
JBrowse link
G RNF103 ring finger protein 103 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:86,603,393...86,623,877
Ensembl chr 2:86,603,398...86,623,866
JBrowse link
G SELP selectin P severity IEP protein:increased expression:plasma RGD PMID:21124648 RGD:6219006 NCBI chr 1:169,588,849...169,630,125
Ensembl chr 1:169,588,849...169,630,193
JBrowse link
G SH2D2A SH2 domain containing 2A IAGP DNA:polymorphism:promoter RGD PMID:15129233 RGD:2298870 NCBI chr 1:156,806,238...156,816,853
Ensembl chr 1:156,806,243...156,816,848
Ensembl chr 1:156,806,243...156,816,848
JBrowse link
G SH3BGRL2 SH3 domain binding glutamate rich protein like 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:79,631,329...79,703,659
Ensembl chr 6:79,631,329...79,703,655
JBrowse link
G SIK1 salt inducible kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr21:43,414,483...43,427,131
Ensembl chr21:43,414,483...43,427,131
JBrowse link
G SIPA1L1 signal induced proliferation associated 1 like 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:71,320,418...71,741,209
Ensembl chr14:71,320,449...71,741,229
JBrowse link
G SLC11A1 solute carrier family 11 member 1 IAGP
EXP
DNA:repeat:promoter (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:16597321, PMID:10857800 RGD:5684977 NCBI chr 2:218,381,766...218,396,894
Ensembl chr 2:218,382,029...218,396,894
JBrowse link
G SLC22A16 solute carrier family 22 member 16 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:110,424,587...110,476,674
Ensembl chr 6:110,424,687...110,476,641
JBrowse link
G SLC26A2 solute carrier family 26 member 2 susceptibility IAGP DNA:SNPs: : RGD PMID:17393463 RGD:13208931 NCBI chr 5:149,960,758...149,987,400
Ensembl chr 5:149,960,758...149,993,455
Ensembl chr 5:149,960,758...149,993,455
JBrowse link
G SLC2A3 solute carrier family 2 member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:7,919,230...7,936,187
Ensembl chr12:7,919,230...7,936,187
JBrowse link
G SMAD3 SMAD family member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:67,065,602...67,195,195
Ensembl chr15:67,063,763...67,195,169
JBrowse link
G STAB1 stabilin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:52,495,338...52,524,496
Ensembl chr 3:52,495,338...52,524,495
JBrowse link
G STAT3 signal transducer and activator of transcription 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr17:42,313,324...42,388,502
Ensembl chr17:42,313,324...42,388,482
Ensembl chr17:42,313,324...42,388,482
JBrowse link
G STIM1 stromal interaction molecule 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr11:3,854,604...4,093,210
Ensembl chr11:3,854,527...4,093,210
JBrowse link
G TCF7L2 transcription factor 7 like 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr10:112,950,247...113,167,678
Ensembl chr10:112,950,247...113,167,678
JBrowse link
G TFDP1 transcription factor Dp-1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:113,584,688...113,641,473
Ensembl chr13:113,584,721...113,641,473
JBrowse link
G TFPI tissue factor pathway inhibitor EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:187,464,230...187,554,501
Ensembl chr 2:187,464,230...187,565,760
JBrowse link
G THBD thrombomodulin IEP protein:increased expression:serum RGD PMID:15209962 RGD:5685023 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672
JBrowse link
G THBS1 thrombospondin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466
JBrowse link
G TNFAIP6 TNF alpha induced protein 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 2:151,357,592...151,380,046
Ensembl chr 2:151,357,592...151,380,046
JBrowse link
G TNFAIP8 TNF alpha induced protein 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 5:119,268,759...119,399,688
Ensembl chr 5:119,268,692...119,399,688
JBrowse link
G TNFRSF10C TNF receptor superfamily member 10c EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 8:23,102,921...23,117,445
Ensembl chr 8:23,102,590...23,117,437
Ensembl chr 8:23,102,590...23,117,437
JBrowse link
G TNIK TRAF2 and NCK interacting kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:171,058,414...171,460,408
Ensembl chr 3:171,058,414...171,460,408
JBrowse link
G TREML1 triggering receptor expressed on myeloid cells like 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:41,149,097...41,158,450
Ensembl chr 6:41,149,342...41,154,337
JBrowse link
G TTLL5 tubulin tyrosine ligase like 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr14:75,661,246...75,955,079
Ensembl chr14:75,633,625...75,955,079
JBrowse link
G TUBB2A tubulin beta 2A class IIa EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:3,153,666...3,157,544
Ensembl chr 6:3,153,666...3,157,544
JBrowse link
G UBE2E1 ubiquitin conjugating enzyme E2 E1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 3:23,805,955...23,891,640
Ensembl chr 3:23,805,955...23,891,640
JBrowse link
G UBE3C ubiquitin protein ligase E3C EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 7:157,138,926...157,269,370
Ensembl chr 7:157,138,916...157,269,370
JBrowse link
G UHRF1BP1L UHRF1 binding protein 1 like EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:100,026,251...100,142,874
Ensembl chr12:100,028,455...100,142,874
JBrowse link
G WASF3 WASP family member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr13:26,539,139...26,688,948
Ensembl chr13:26,557,683...26,688,948
JBrowse link
G WWOX WW domain containing oxidoreductase EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr16:78,099,654...79,212,667
Ensembl chr16:78,099,430...79,212,667
JBrowse link
G ZFAND3 zinc finger AN1-type containing 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr 6:37,819,727...38,154,624
Ensembl chr 6:37,819,727...38,154,624
JBrowse link
G ZFC3H1 zinc finger C3H1-type containing EXP CTD Direct Evidence: marker/mechanism CTD PMID:19565504 NCBI chr12:71,609,599...71,663,848
Ensembl chr12:71,609,472...71,667,725
Ensembl chr12:71,609,472...71,667,725
JBrowse link
Knee Osteoarthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA2 annexin A2 disease_progression IEP protein:increased expression:chondrocyte: RGD PMID:10903884 RGD:10053727 NCBI chr15:60,347,151...60,398,025
Ensembl chr15:60,347,134...60,402,883
JBrowse link
G ANXA5 annexin A5 disease_progression IEP protein:increased expression:chondrocyte: RGD PMID:10903884 RGD:10053727 NCBI chr 4:121,667,946...121,696,994
Ensembl chr 4:121,667,946...121,696,995
JBrowse link
G AR androgen receptor IAGP DNA:repeat:exon:c.172(CAG)8-34 (human) RGD PMID:16098017 RGD:10043199 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619
JBrowse link
G ASPN asporin severity IEP
IAGP
mRNA:increased expression:cartilage:
DNA:repeats:exon:
RGD PMID:15640800, PMID:15640800 RGD:9684965, RGD:9684965 NCBI chr 9:92,456,205...92,482,506
Ensembl chr 9:92,456,205...92,482,506
JBrowse link
G B2M beta-2-microglobulin IEP protein:increased expression:serum RGD PMID:18795399 RGD:6482710 NCBI chr15:44,711,492...44,718,145
Ensembl chr15:44,711,487...44,718,877
JBrowse link
G BAX BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:20131282 RGD:6907382 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO RGD PMID:20131282 RGD:6907382 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein IEP
ISO
RGD PMID:22294259, PMID:21387139 RGD:6483563, RGD:6483595 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO mRNA,protein:increased expression:dorsal root ganglion: RGD PMID:23185004 RGD:8661785 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,744...46,360,940
Ensembl chr 3:46,353,744...46,360,940
JBrowse link
G CD36 CD36 molecule disease_progression IEP
ISO
RGD PMID:21765106, PMID:19342682 RGD:6893494, RGD:6893565 NCBI chr 7:80,602,207...80,679,277
Ensembl chr 7:80,369,575...80,679,277
JBrowse link
G CTNNB1 catenin beta 1 ISO protein:increased expression:cartilage: RGD PMID:22702043 RGD:10395278 NCBI chr 3:41,199,422...41,240,445
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 IAGP DNA:SNP:intron, 5' utr: (rs1062033) (human) RGD PMID:20417295 RGD:10045662 NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601
JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 severity IEP mRNA,protein:increased expression:fat pad: RGD PMID:21765106 RGD:6893494 NCBI chr11:75,768,778...75,801,534
Ensembl chr11:75,759,512...75,801,535
JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 ISO RGD PMID:20131282 RGD:6907382 NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042
JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 ISO RGD PMID:25435813 RGD:13506963 NCBI chr 6:73,515,750...73,521,032
Ensembl chr 6:73,515,750...73,523,797
JBrowse link
G EFEMP1 EGF containing fibulin extracellular matrix protein 1 IEP protein:increased expression:serum: RGD PMID:22275171 RGD:10401792 NCBI chr 2:55,865,967...55,924,163
Ensembl chr 2:55,865,967...55,924,139
JBrowse link
G EPAS1 endothelial PAS domain protein 1 no_association IAGP DNA:SNP:5' utr: (rs17039192) (human) RGD PMID:22247019, PMID:20495570 RGD:10395367, RGD:10395368 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697
JBrowse link
G EPO erythropoietin treatment IDA RGD PMID:25422652 RGD:10400892 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700
JBrowse link
G ESR1 estrogen receptor 1 IAGP DNA:repeat:promoter:-1174(TA)9-25 (human)
DNA:polymorphisms, haplotype:intron, exon
DNA:SNP:cds:c.1782G>A (rs2228480) (human)
DNA:SNPs:intron: (rs2234693, rs9340799) (human)
RGD PMID:16098017, PMID:15380041, PMID:20128071, PMID:24772413 RGD:10043199, RGD:10045840, RGD:10045835, RGD:10045829 NCBI chr 6:151,654,148...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G ESR2 estrogen receptor 2 IAGP DNA:repeat:intron:c.1092+3607(CA)13-27 (human) RGD PMID:16098017 RGD:10043199 NCBI chr14:64,226,707...64,338,631
Ensembl chr14:64,084,232...64,338,112
JBrowse link
G F2 coagulation factor II, thrombin IDA RGD PMID:21041276 RGD:5147774 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G FGFR3 fibroblast growth factor receptor 3 treatment ISO RGD PMID:27159076 RGD:11568056 NCBI chr 4:1,793,293...1,808,872
Ensembl chr 4:1,793,293...1,808,872
JBrowse link
G GDF5 growth differentiation factor 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr20:35,433,347...35,454,749
Ensembl chr20:35,433,347...35,454,746
JBrowse link
G GSR glutathione-disulfide reductase IEP protein:increased expression:synovial fluid RGD PMID:16289733 RGD:10401830 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G HMGB1 high mobility group box 1 severity IEP protein:increased expression:synovial fluid
mRNA:decreased expression:articular cartilage
RGD PMID:21968272, PMID:19139395 RGD:10402061, RGD:10402184 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597
JBrowse link
G HMGB2 high mobility group box 2 severity IEP
ISO
mRNA:decreased expression:articular cartilage RGD PMID:19139395, PMID:19139395 RGD:10402184, RGD:10402184 NCBI chr 4:173,331,376...173,334,358
Ensembl chr 4:173,331,376...173,334,432
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 ISO
IEP
mRNA:increased expression:tibial plateaux (mouse)
mRNA:decreased expression:blood (human)
RGD PMID:9497939, PMID:16139532 RGD:10412655, RGD:10429075 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,738...102,139,699
Ensembl chr14:102,080,738...102,139,699
JBrowse link
G IGF1 insulin like growth factor 1 disease_progression
severity
IEP
ISO
protein:decreased expression:plasma (rat)
mRNA:increased expression:meniscus:
RGD PMID:8461919, PMID:17133593, PMID:9497937, PMID:20633672 RGD:10045862, RGD:10003130, RGD:10046057, RGD:10045868 NCBI chr12:102,395,860...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G IGF1R insulin like growth factor 1 receptor IEP RGD PMID:8948288 RGD:10045874 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530
JBrowse link
G IL1A interleukin 1 alpha ISO
IEP
protein:increased expression:cartilage cell: RGD PMID:24534736, PMID:9497937, PMID:9034998 RGD:10045944, RGD:10046057, RGD:10045946 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL2 interleukin 2 severity IEP protein:increased expression:synovial fluid: RGD PMID:22035391 RGD:5687147 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL4 interleukin 4 susceptibility ISO
IAGP
DNA:repeat:intron: (rs8179190) (human) RGD PMID:18182309, PMID:24406619 RGD:2317291, RGD:10402787 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G KL klotho susceptibility IAGP DNA:SNPs:promoter,exon:395G>A,2998C>T(human) RGD PMID:18465812 RGD:10403041 NCBI chr13:33,016,063...33,066,143
Ensembl chr13:33,016,423...33,066,143
JBrowse link
G LEP leptin IEP protein:decreased expression:serum: RGD PMID:23575542 RGD:10411887 NCBI chr 7:128,241,201...128,257,629
Ensembl chr 7:128,241,278...128,257,629
JBrowse link
G LEPR leptin receptor susceptibility IEP
IAGP
protein:increased expression:serum:
DNA:SNP:cds:668A>G(human)
RGD PMID:23575542, PMID:23575542 RGD:10411887, RGD:10411887 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559
JBrowse link
G LPAR1 lysophosphatidic acid receptor 1 susceptibility IAGP DNA:snp:promoter:g.-2820G>A (rs10980705) (human) RGD PMID:18325907 RGD:10054291 NCBI chr 9:110,873,252...111,038,998
Ensembl chr 9:110,873,263...111,038,458
JBrowse link
G LTBP1 latent transforming growth factor beta binding protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr 2:32,902,129...33,399,509
Ensembl chr 2:32,946,953...33,399,509
JBrowse link
G MIR223 microRNA 223 ISO RNA:increased expression:synovial membrane RGD PMID:30106113 RGD:25824950 NCBI chr  X:66,018,870...66,018,979
Ensembl chr  X:66,018,870...66,018,979
JBrowse link
G MMP1 matrix metallopeptidase 1 treatment ISO RGD PMID:21167838 RGD:8549737 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,919...102,798,160
JBrowse link
G MMP3 matrix metallopeptidase 3 treatment ISO RGD PMID:22114772 RGD:8694098 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609
JBrowse link
G PENK proenkephalin treatment ISO RGD PMID:21928671 RGD:10003115 NCBI chr 8:56,440,957...56,446,641
Ensembl chr 8:56,436,674...56,446,671
JBrowse link
G PTGES prostaglandin E synthase ISO RGD PMID:17530714 RGD:2300093 NCBI chr 9:129,738,349...129,753,042
Ensembl chr 9:129,738,331...129,753,042
JBrowse link
G SBNO1 strawberry notch homolog 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr12:123,289,109...123,364,847
Ensembl chr12:123,289,109...123,364,847
JBrowse link
G SLC26A2 solute carrier family 26 member 2 susceptibility IAGP DNA:deletion:promoter:-716_-713del4A(human) RGD PMID:11558903 RGD:13208866 NCBI chr 5:149,960,758...149,987,400
Ensembl chr 5:149,960,758...149,993,455
Ensembl chr 5:149,960,758...149,993,455
JBrowse link
G TGFA transforming growth factor alpha IEP mRNA:increased expression:cartilage RGD PMID:17968906 RGD:2317486 NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193
JBrowse link
G VDR vitamin D receptor IEA GAD PMID:15118671 RGD:1331525 NCBI chr12:47,841,537...47,905,022
Ensembl chr12:47,841,537...47,943,048
JBrowse link
G WWP2 WW domain containing E3 ubiquitin protein ligase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr16:69,762,301...69,941,741
Ensembl chr16:69,762,306...69,941,741
JBrowse link
limited scleroderma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV1 caveolin 1 susceptibility
no_association
IAGP DNA:SNPs:enhancer, intron:multiple
DNA:SNPs:3' utr, intron: (rs9920, rs729949, rs3815412) (human)
RGD PMID:22402147, PMID:22402147 RGD:8661768, RGD:8661768 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,525,001...116,561,184
JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO mRNA,protein:increased expression:skin RGD PMID:12925209 RGD:8661733 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,218...34,257,203
JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO mRNA,protein:increased expression:skin: RGD PMID:12925209 RGD:8661733 NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,744...46,360,940
Ensembl chr 3:46,353,744...46,360,940
JBrowse link
G FAS Fas cell surface death receptor ISO RGD PMID:17102953 RGD:12903974 NCBI chr10:88,968,429...89,017,059
Ensembl chr10:88,990,531...89,017,059
JBrowse link
G FASLG Fas ligand ISO RGD PMID:17102953 RGD:12903974 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
JBrowse link
G IL2 interleukin 2 susceptibility IAGP DNA:polymorphism::-384T>G(human) RGD PMID:17444587 RGD:4142872 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G JAK2 Janus kinase 2 IEP RGD PMID:20808962 RGD:4892610 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,128,183
Ensembl chr 9:4,984,390...5,128,183
JBrowse link
G KDR kinase insert domain receptor IEP protein:increased expression:serum: RGD PMID:19886888 RGD:8551850 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595
JBrowse link
G PGF placental growth factor IEP protein:increased expression:plasma RGD PMID:22461185 RGD:6483571 NCBI chr14:74,941,830...74,955,764
Ensembl chr14:74,941,834...74,955,626
JBrowse link
G SERPINE1 serpin family E member 1 ISO mRNA,protein:increased expression:skin: RGD PMID:15730388 RGD:13208597 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G STAT4 signal transducer and activator of transcription 4 no_association
susceptibility
IAGP DNA:SNPs:introns: (rs10168266, rs3821236) (human)
DNA:SNP:intron: (rs7574865) (human)
RGD PMID:23755762, PMID:23755762, PMID:19286670 RGD:8661701, RGD:8661701, RGD:8661714 NCBI chr 2:191,029,576...191,172,684
Ensembl chr 2:191,029,576...191,151,596
JBrowse link
G TAP2 transporter 2, ATP binding cassette subfamily B member susceptibility IAGP RGD PMID:16112028 RGD:1578361 NCBI chr 6:32,821,831...32,838,739
Ensembl chr 6:32,821,833...32,838,770
JBrowse link
Lipodermatosclerosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain IEP mRNA:increased expression:dermis RGD PMID:15727634 RGD:5688298 NCBI chr17:50,184,096...50,201,649
Ensembl chr17:50,183,289...50,201,632
Ensembl chr17:50,183,289...50,201,632
JBrowse link
localized scleroderma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN1A cyclin dependent kinase inhibitor 1A ISO mRNA,protein:increased expression:skin: RGD PMID:15803328 RGD:8662838 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,339
Ensembl chr 6:36,676,460...36,687,339
JBrowse link
G CSF3 colony stimulating factor 3 EXP CTD Direct Evidence: therapeutic CTD PMID:15863969 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813
JBrowse link
G HGF hepatocyte growth factor treatment IDA RGD PMID:14712301 RGD:8548627 NCBI chr 7:81,699,006...81,770,438
Ensembl chr 7:81,699,010...81,770,438
JBrowse link
G ICAM1 intercellular adhesion molecule 1 IEP protein:increased expression:serum RGD PMID:7916356 RGD:8158116 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IL13 interleukin 13 IEP protein:increased expression:serum RGD PMID:12920362 RGD:8549537 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
JBrowse link
G LMNA lamin A/C EXP CTD Direct Evidence: marker/mechanism CTD PMID:15726408 NCBI chr 1:156,082,573...156,140,081
Ensembl chr 1:156,082,573...156,140,089
JBrowse link
G MMP1 matrix metallopeptidase 1 IDA RGD PMID:9804345 RGD:1582543 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,919...102,798,160
JBrowse link
G TGFB1 transforming growth factor beta 1 IEP RGD PMID:7510487 RGD:7394847 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TNF tumor necrosis factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:9843018 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
nodular nonsuppurative panniculitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SERPINA1 serpin family A member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:3259592, PMID:6982619 NCBI chr14:94,376,747...94,390,654
Ensembl chr14:94,376,747...94,390,693
JBrowse link
osteoarthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC079145.1 novel transcript IAGP ClinVar Annotator: match by term: OSTEOARTHRITIS OF DISTAL INTERPHALANGEAL JOINTS ClinVar PMID:12736871 NCBI chr 2:19,990,204...20,004,806
Ensembl chr 2:19,990,209...20,004,795
JBrowse link
G ACAA2 acetyl-CoA acyltransferase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr18:49,782,164...49,813,533
Ensembl chr18:49,782,164...49,813,953
JBrowse link
G ACAN aggrecan treatment ISO RGD PMID:22833446, PMID:21853458 RGD:11570535, RGD:11570544 NCBI chr15:88,803,436...88,875,353
Ensembl chr15:88,803,436...88,875,354
Ensembl chr15:88,803,436...88,875,354
JBrowse link
G ACO1 aconitase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 9:32,384,643...32,454,769
Ensembl chr 9:32,384,603...32,454,769
JBrowse link
G ACTB actin beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902
Ensembl chr 7:5,526,409...5,563,902
JBrowse link
G ADAM12 ADAM metallopeptidase domain 12 susceptibility IAGP RGD PMID:15334463 RGD:1625347 NCBI chr10:126,012,391...126,388,477
Ensembl chr10:126,012,381...126,388,455
JBrowse link
G ADAM15 ADAM metallopeptidase domain 15 ISO RGD PMID:15818704 RGD:1559176 NCBI chr 1:155,051,316...155,062,775
Ensembl chr 1:155,050,566...155,062,775
JBrowse link
G ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif 14 IAGP DNA:missense mutation:cds: (rs4747096) (human) RGD PMID:18790654 RGD:6771189 NCBI chr10:70,672,506...70,762,441
Ensembl chr10:70,672,506...70,762,441
JBrowse link
G ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif 4 treatment ISO associated with Bone Diseases, Metabolic RGD PMID:22432033 RGD:10043110 NCBI chr 1:161,184,302...161,202,339
Ensembl chr 1:161,184,302...161,199,054
JBrowse link
G ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 treatment
disease_progression
no_association
ISO
IEP
IAGP
associated with Bone Diseases, Metabolic
mRNA:increased expression:cartilage
protein:alternative form:synovium
DNA:missense mutations:exon: (rs226794, rs2830585) (human)
DNA:missense mutation:exon:p.R614H (human)
RGD PMID:23982761, PMID:22432033, PMID:17530714, PMID:22084394, PMID:23954517, PMID:11801682, PMID:18240210, PMID:23546441, PMID:22961118 RGD:10043101, RGD:10043110, RGD:2300093, RGD:10003165, RGD:10043107, RGD:10043106, RGD:10043105, RGD:10043103, RGD:10043102 NCBI chr21:26,917,922...26,967,758
Ensembl chr21:26,917,922...26,967,088
JBrowse link
G ADGRG2 adhesion G protein-coupled receptor G2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr  X:18,989,307...19,122,956
Ensembl chr  X:18,989,307...19,122,637
JBrowse link
G AGER advanced glycosylation end-product specific receptor treatment ISO
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:16948116, PMID:23894457 RGD:8695985 NCBI chr 6:32,180,969...32,184,380
Ensembl chr 6:32,180,968...32,184,322
JBrowse link
G AK4 adenylate kinase 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 1:65,147,342...65,232,145
Ensembl chr 1:65,147,549...65,232,145
JBrowse link
G AKR1C1 aldo-keto reductase family 1 member C1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr10:4,963,415...4,983,283
Ensembl chr10:4,963,253...4,983,283
JBrowse link
G AKR1C2 aldo-keto reductase family 1 member C2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr10:4,987,775...5,018,000
Ensembl chr10:4,987,400...5,018,031
JBrowse link
G ALDH1A2 aldehyde dehydrogenase 1 family member A2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24728293 NCBI chr15:57,953,429...58,065,711
Ensembl chr15:57,953,424...58,497,866
JBrowse link
G ASPN asporin no_association
susceptibility
IAGP
EXP
DNA:repeats:exon:
CTD Direct Evidence: marker/mechanism
CTD
OMIM
PMID:16542493 RGD:9684966 NCBI chr 9:92,456,205...92,482,506
Ensembl chr 9:92,456,205...92,482,506
JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr19:41,966,582...41,994,230
Ensembl chr19:41,966,582...41,997,497
JBrowse link
G ATP6V1B2 ATPase H+ transporting V1 subunit B2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 8:20,197,375...20,226,852
Ensembl chr 8:20,197,381...20,226,819
JBrowse link
G ATP7A ATPase copper transporting alpha ISS OMIM:140600 | OMIM:165720 | OMIM:607850 | OMIM:612400 MouseDO NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,656...78,050,395
JBrowse link
G BAD BCL2 associated agonist of cell death IEP RGD PMID:19217321 RGD:10053643 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704
JBrowse link
G BAG6 BAG cochaperone 6 susceptibility IAGP DNA:SNP: :rs3117582(human) RGD PMID:25231575 RGD:14390133 NCBI chr 6:31,639,028...31,660,900
Ensembl chr 6:31,639,028...31,652,705
JBrowse link
G BAX BCL2 associated X, apoptosis regulator IEP protein:increased expression:chondrocyte RGD PMID:19217321, PMID:16864079 RGD:10053643, RGD:10054095 NCBI chr19:48,954,825...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator IEP protein:increased expression:chondrocyte RGD PMID:19217321, PMID:16864079 RGD:10053643, RGD:10054095 NCBI chr18:63,123,346...63,320,280
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BECN1 beclin 1 IEP
ISO
protein:decreased expression:cartilage RGD PMID:20187128, PMID:20187128 RGD:6483317, RGD:6483317 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein disease_progression IDA RGD PMID:20157712 RGD:6483599 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
JBrowse link
G BMP2 bone morphogenetic protein 2 susceptibility IAGP RGD PMID:15334463 RGD:1625347 NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246
JBrowse link
G BMP4 bone morphogenetic protein 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
JBrowse link
G BMP6 bone morphogenetic protein 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728
JBrowse link
G BMP7 bone morphogenetic protein 7 ISS OMIM:140600 | OMIM:165720 | OMIM:607850 | OMIM:610839 | OMIM:612400 | OMIM:612401 MouseDO NCBI chr20:57,168,753...57,266,641
Ensembl chr20:57,168,753...57,266,641
JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A ISS OMIM:140600 | OMIM:165720 | OMIM:607850 | OMIM:610839 | OMIM:612400 | OMIM:612401 MouseDO NCBI chr10:86,755,786...86,927,969
Ensembl chr10:86,756,601...86,932,838
Ensembl chr10:86,756,601...86,932,838
JBrowse link
G CALCA calcitonin related polypeptide alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:16690336 NCBI chr11:14,966,668...14,972,361
Ensembl chr11:14,966,668...14,972,354
JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:29138829 RGD:13782343 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP9 caspase 9 treatment ISO RGD PMID:29138829 RGD:13782343 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAV1 caveolin 1 ISO RGD PMID:16508959 RGD:10043354 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,525,001...116,561,184
JBrowse link
G CCL22 C-C motif chemokine ligand 22 IEP protein:increased expression:plasma: RGD PMID:19942450 RGD:10054497 NCBI chr16:57,358,783...57,366,189
Ensembl chr16:57,358,783...57,366,189
JBrowse link
G CCR4 C-C motif chemokine receptor 4 IEP protein:increased expression:synovial membrane: RGD PMID:19942450 RGD:10054497 NCBI chr 3:32,951,555...32,956,349
Ensembl chr 3:32,951,644...32,956,349
JBrowse link
G CD36 CD36 molecule susceptibility IAGP RGD PMID:15334463 RGD:1625347 NCBI chr 7:80,602,207...80,679,277
Ensembl chr 7:80,369,575...80,679,277
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A treatment ISO RGD PMID:24009074 RGD:10043190 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,753...21,995,301
JBrowse link
G CEBPB CCAAT enhancer binding protein beta susceptibility ISO RGD PMID:22095691 RGD:10401214 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668
JBrowse link
G CHI3L1 chitinase 3 like 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704
JBrowse link
G CILP cartilage intermediate layer protein disease_progression IAGP RGD PMID:15334463 RGD:1625347 NCBI chr15:65,194,760...65,213,142
Ensembl chr15:65,194,760...65,211,473
JBrowse link
G CLEC3B C-type lectin domain family 3 member B disease_progression IAGP RGD PMID:15334463 RGD:1625347 NCBI chr 3:45,026,207...45,036,071
Ensembl chr 3:45,001,548...45,036,071
JBrowse link
G CLIC1 chloride intracellular channel 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 6:31,730,581...31,737,318
Ensembl chr 6:31,730,581...31,739,763
JBrowse link
G CLIC4 chloride intracellular channel 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 1:24,745,447...24,844,321
Ensembl chr 1:24,745,382...24,844,321
JBrowse link
G CLU clusterin EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789, PMID:18784066 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700
JBrowse link
G COL11A1 collagen type XI alpha 1 chain ISS OMIM:140600 | OMIM:165720 | OMIM:607850 | OMIM:610839 | OMIM:612400 | OMIM:612401 MouseDO NCBI chr 1:102,876,473...103,108,580
Ensembl chr 1:102,876,467...103,108,872
JBrowse link
G COL1A1 collagen type I alpha 1 chain no_association IAGP DNA:SNP:intron:IVS1 RGD PMID:10743824 RGD:5688331 NCBI chr17:50,184,096...50,201,649
Ensembl chr17:50,183,289...50,201,632
Ensembl chr17:50,183,289...50,201,632
JBrowse link
G COL1A2 collagen type I alpha 2 chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 7:94,394,895...94,431,227
Ensembl chr 7:94,394,895...94,431,227
Ensembl chr 7:94,394,895...94,431,227
JBrowse link
G COL2A1 collagen type II alpha 1 chain onset
treatment
IAGP
EXP
ISO
DNA:missense mutation:exon:p.R75C (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:9061443, PMID:16189708, PMID:16755660, PMID:19216861 RGD:8657384, RGD:8661226 NCBI chr12:47,972,967...48,006,212
Ensembl chr12:47,972,967...48,004,554
JBrowse link
G COL6A2 collagen type VI alpha 2 chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr21:46,098,071...46,132,849
Ensembl chr21:46,098,112...46,132,848
Ensembl chr21:46,098,112...46,132,848
JBrowse link
G COL9A1 collagen type IX alpha 1 chain ISS OMIM:140600 | OMIM:165720 | OMIM:607850 | OMIM:610839 | OMIM:612400 | OMIM:612401 MouseDO NCBI chr 6:70,215,061...70,303,084
Ensembl chr 6:70,215,061...70,303,083
JBrowse link
G COMP cartilage oligomeric matrix protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:7670472 NCBI chr19:18,782,773...18,791,305
Ensembl chr19:18,782,773...18,791,305
JBrowse link
G CTSD cathepsin D EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,755...1,764,573
JBrowse link
G CTSK cathepsin K EXP CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chr 1:150,796,208...150,808,260
Ensembl chr 1:150,796,208...150,808,260
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064
JBrowse link
G DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 4:99,816,827...99,872,290
Ensembl chr 4:99,816,827...99,870,190
JBrowse link
G DDX3X DEAD-box helicase 3 X-linked EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr  X:41,333,308...41,364,472
Ensembl chr  X:41,333,348...41,364,472
Ensembl chr  X:41,333,348...41,364,472
JBrowse link
G DPEP1 dipeptidase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chr16:89,613,308...89,641,540
Ensembl chr16:89,613,308...89,638,456
JBrowse link
G DPYSL2 dihydropyrimidinase like 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 8:26,514,031...26,658,175
Ensembl chr 8:26,514,031...26,658,178
JBrowse link
G EDIL3 EGF like repeats and discoidin domains 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 5:83,940,554...84,384,880
Ensembl chr 5:83,940,554...84,384,880
JBrowse link
G EEF2 eukaryotic translation elongation factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr19:3,976,056...3,985,463
Ensembl chr19:3,976,056...3,985,463
JBrowse link
G EGR1 early growth response 1 IEP mRNA, protein: decreased expression RGD PMID:10806043 RGD:1626498 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G ENO1 enolase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190
JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISS OMIM:140600 | OMIM:165720 | OMIM:607850 | OMIM:610839 | OMIM:612400 | OMIM:612401 MouseDO NCBI chr 6:131,808,020...131,895,155
Ensembl chr 6:131,808,016...131,895,155
JBrowse link
G EPAS1 endothelial PAS domain protein 1 ISO
IEP
protein:increased expression:layer of synovial tissue, stromal cell
mRNA:increased expression:cartilage
RGD PMID:21869830, PMID:12823854, PMID:20495569, PMID:20495569 RGD:10395364, RGD:10395366, RGD:10395365, RGD:10395365 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697
JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit ISO mRNA:decreased expression:knee, articular cartilage of joint RGD PMID:24964749 RGD:10045611 NCBI chr19:45,407,334...45,451,547
Ensembl chr19:45,407,333...45,478,828
Ensembl chr19:45,407,333...45,478,828
JBrowse link
G ERG ETS transcription factor ERG ISS OMIM:140600 | OMIM:165720 | OMIM:607850 | OMIM:610839 | OMIM:612400 | OMIM:612401 MouseDO NCBI chr21:38,367,261...38,661,783
Ensembl chr21:38,380,027...38,661,780
JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 ISS OMIM:140600 | OMIM:165720 | OMIM:607850 | OMIM:610839 | OMIM:612400 | OMIM:612401 MouseDO NCBI chr 1:8,011,725...8,026,309
Ensembl chr 1:8,004,404...8,026,309
JBrowse link
G ESD esterase D EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr13:46,771,256...46,797,700
Ensembl chr13:46,771,256...46,797,420
Ensembl chr13:46,771,256...46,797,420
JBrowse link
G ESR1 estrogen receptor 1 IAGP DNA:SNP:intron: (rs2234693) (human)
DNA:SNPs:introns: (rs2234693, rs9340799) (human)
RGD PMID:20417295, PMID:19884274 RGD:10045662, RGD:10045830 NCBI chr 6:151,654,148...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G ESR2 estrogen receptor 2 IAGP DNA:SNP:intron: (rs1256031) (human) RGD PMID:19884274 RGD:10045830 NCBI chr14:64,226,707...64,338,631
Ensembl chr14:64,084,232...64,338,112
JBrowse link
G ETFA electron transfer flavoprotein subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr15:76,215,353...76,311,469
Ensembl chr15:76,215,353...76,311,472
JBrowse link
G EZR ezrin EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 6:158,765,744...158,819,368
Ensembl chr 6:158,765,741...158,819,368
JBrowse link
G FCGR2A Fc fragment of IgG receptor IIa IDA RGD PMID:8254199 RGD:5147984 NCBI chr 1:161,505,430...161,524,048
Ensembl chr 1:161,505,430...161,524,013
JBrowse link
G FGF18 fibroblast growth factor 18 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chr 5:171,419,647...171,457,626
Ensembl chr 5:171,419,647...171,457,626
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 IDA RGD PMID:22393163 RGD:10402075 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 IEP mRNA:increased expression:trabecular bone: RGD PMID:15781004 RGD:10402109 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145
JBrowse link
G FN1 fibronectin 1 IEP protein:increased expression:cartilage: RGD PMID:8646429 RGD:10402156 NCBI chr 2:215,360,862...215,436,167
Ensembl chr 2:215,360,440...215,436,073
JBrowse link
G FRZB frizzled related protein susceptibility IAGP
EXP
ClinVar Annotator: match by term: Osteoarthritis susceptibility 1
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
OMIM
PMID:15210948, PMID:25741868 NCBI chr 2:182,833,275...182,866,637
Ensembl chr 2:182,833,275...182,866,637
JBrowse link
G FTL ferritin light chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr19:48,963,941...48,966,879
Ensembl chr19:48,965,309...48,966,879
JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374
JBrowse link
G GDF5 growth differentiation factor 5 IAGP
EXP
CTD Direct Evidence: marker/mechanism OMIM
CTD
PMID:18830904, PMID:30664745 NCBI chr20:35,433,347...35,454,749
Ensembl chr20:35,433,347...35,454,746
JBrowse link
G GH1 growth hormone 1 IEP protein:increased expression:plasma RGD PMID:7152485 RGD:10003140 NCBI chr17:63,917,203...63,918,839
Ensembl chr17:63,917,200...63,918,839
JBrowse link
G GHR growth hormone receptor IAGP DNA:deletion:exon: RGD PMID:23740230 RGD:10003113 NCBI chr 5:42,423,439...42,721,878
Ensembl chr 5:42,423,439...42,721,878
JBrowse link
G GLS glutaminase EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 2:190,880,821...190,965,552
Ensembl chr 2:190,880,821...190,965,552
Ensembl chr 2:190,880,821...190,965,552
JBrowse link
G GSTK1 glutathione S-transferase kappa 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 7:143,263,441...143,269,115
Ensembl chr 7:143,244,093...143,270,854
JBrowse link
G HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 2:26,190,635...26,244,632
Ensembl chr 2:26,190,635...26,244,672
JBrowse link
G HBP1 HMG-box transcription factor 1 IEP RGD PMID:22586168 RGD:10402054 NCBI chr 7:107,168,987...107,202,523
Ensembl chr 7:107,168,961...107,202,522
JBrowse link
G HFE homeostatic iron regulator IAGP DNA:missense mutation: :p.C282Y (rs1800562) (human) RGD PMID:30651232 RGD:14746965 NCBI chr 6:26,087,347...26,098,343
Ensembl chr 6:26,087,281...26,098,343
JBrowse link
G HIBCH 3-hydroxyisobutyryl-CoA hydrolase EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 2:190,203,920...190,319,826
Ensembl chr 2:190,189,735...190,344,193
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha IEP
ISO
protein:increased expression:layer of synovial tissue, stromal cell RGD PMID:12823854, PMID:18789153 RGD:10395366, RGD:10402406 NCBI chr14:61,695,513...61,748,259
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HMGB1 high mobility group box 1 ISO RGD PMID:22330250 RGD:10401949 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597
JBrowse link
G IDH2 isocitrate dehydrogenase (NADP(+)) 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr15:90,083,045...90,102,468
Ensembl chr15:90,083,045...90,102,504
Ensembl chr15:90,083,045...90,102,504
JBrowse link
G IDH3A isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr15:78,149,362...78,171,945
Ensembl chr15:78,131,498...78,171,945
JBrowse link
G IFNA6 interferon alpha 6 treatment ISO RGD PMID:30456844 RGD:36174218 NCBI chr 9:21,350,318...21,350,887
Ensembl chr 9:21,349,835...21,351,378
JBrowse link
G IGF1 insulin like growth factor 1 IEP protein:decreased expression:blood: RGD PMID:2290165 RGD:10045857 NCBI chr12:102,395,860...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G IGF1R insulin like growth factor 1 receptor severity IEP mRNA:increased expression:articular cartilage of joint: RGD PMID:8609369 RGD:10045889 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530
JBrowse link
G IGF2 insulin like growth factor 2 IEP mRNA:increased expression:cartilage RGD PMID:22527881 RGD:10402552 NCBI chr11:2,129,112...2,149,603
Ensembl chr11:2,129,112...2,141,238
JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 IEP RGD PMID:18775662 RGD:10402575 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874
JBrowse link
G IHH Indian hedgehog signaling molecule IEP
ISO
protein:increased expression:cartilage RGD PMID:24786088, PMID:24786088 RGD:12910979, RGD:12910979 NCBI chr 2:219,054,424...219,060,921
Ensembl chr 2:219,054,424...219,060,921
JBrowse link
G IL1A interleukin 1 alpha IEP protein:increased expression:chonodrocyte: RGD PMID:9497936 RGD:10047053 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta treatment ISO
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:21954917, PMID:22890185 RGD:7207218 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL4R interleukin 4 receptor IEP protein:increased expression:serum RGD PMID:16647277 RGD:10402785 NCBI chr16:27,313,668...27,364,778
Ensembl chr16:27,313,668...27,364,778
JBrowse link
G IL5 interleukin 5 IEP RGD PMID:22035391 RGD:5687147 NCBI chr 5:132,539,194...132,556,864
Ensembl chr 5:132,541,445...132,556,838
JBrowse link
G IMMT inner membrane mitochondrial protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 2:86,143,932...86,195,463
Ensembl chr 2:86,143,932...86,195,770
JBrowse link
G INS insulin IEP protein:increased expression:blood: RGD PMID:2290165 RGD:10045857 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,341
Ensembl chr11:2,159,779...2,161,341
JBrowse link
G ISOC2 isochorismatase domain containing 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr19:55,452,985...55,461,642
Ensembl chr19:55,452,985...55,462,343
JBrowse link
G JAG1 jagged canonical Notch ligand 1 IEP RGD PMID:18354251 RGD:6482239 NCBI chr20:10,637,684...10,673,999
Ensembl chr20:10,637,684...10,673,999
JBrowse link
G LEP leptin severity IEP protein:increased expression:tibia, cartilage, chondrocyte (human) RGD PMID:14613274 RGD:10053634 NCBI chr 7:128,241,201...128,257,629
Ensembl chr 7:128,241,278...128,257,629
JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:11790802, PMID:12379497 NCBI chr11:65,538,559...65,558,389
Ensembl chr11:65,538,805...65,558,930
JBrowse link
G MATN3 matrilin 3 susceptibility IAGP
EXP
ClinVar Annotator: match by term: OSTEOARTHRITIS OF DISTAL INTERPHALANGEAL JOINTS
CTD Direct Evidence: marker/mechanism
OMIM
ClinVar
CTD
PMID:12736871 NCBI chr 2:19,992,052...20,012,668
Ensembl chr 2:19,992,052...20,012,668
JBrowse link
G MMP1 matrix metallopeptidase 1 IEP protein:increased expression:plasma (human) RGD PMID:9972954 RGD:7207129 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,919...102,798,160
JBrowse link
G MMP13 matrix metallopeptidase 13 treatment IDA
IMP
ISO
mRNA, protein:increased expression:cartilage RGD PMID:16128596, PMID:11134178, PMID:17530714, PMID:23982761, PMID:22890185 RGD:7207089, RGD:10043117, RGD:2300093, RGD:10043101, RGD:7207218 NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732
JBrowse link
G MMP2 matrix metallopeptidase 2 IEP protein:increased expression:synovial fluid (human) RGD PMID:15194590 RGD:7207131 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
JBrowse link
G MMP3 matrix metallopeptidase 3 IDA
IEP
protein:increased expression:synovial fluid (human) RGD PMID:16128596, PMID:15194590 RGD:7207089, RGD:7207131 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609
JBrowse link
G MMP8 matrix metallopeptidase 8 IEP protein:increased expression:synovial fluid, serum (human) RGD PMID:15194590 RGD:7207131 NCBI chr11:102,711,796...102,724,967
Ensembl chr11:102,711,796...102,727,050
JBrowse link
G MMP9 matrix metallopeptidase 9 IEP protein:increased expression:synovial fluid, serum (human) RGD PMID:15194590 RGD:7207131 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MSN moesin EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr  X:65,588,382...65,741,931
Ensembl chr  X:65,588,377...65,741,931
JBrowse link
G MTOR mechanistic target of rapamycin kinase treatment ISO RGD PMID:24651621, PMID:22084394 RGD:10003163, RGD:10003165 NCBI chr 1:11,106,535...11,273,497
Ensembl chr 1:11,106,535...11,262,551
JBrowse link
G MVP major vault protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr16:29,820,394...29,848,039
Ensembl chr16:29,820,394...29,848,039
JBrowse link
G MYH13 myosin heavy chain 13 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr17:10,300,865...10,373,006
Ensembl chr17:10,300,865...10,373,130
JBrowse link
G NAPEPLD N-acyl phosphatidylethanolamine phospholipase D ISO protein:increased expression:spinal cord RGD PMID:20722027 RGD:10412653 NCBI chr 7:103,099,776...103,150,001
Ensembl chr 7:103,099,776...103,149,560
JBrowse link
G NCOR2 nuclear receptor corepressor 2 susceptibility IAGP RGD PMID:15334463 RGD:1625347 NCBI chr12:124,324,415...124,567,612
Ensembl chr12:124,324,415...124,567,589
JBrowse link
G NDUFS8 NADH:ubiquinone oxidoreductase core subunit S8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr11:68,030,681...68,036,644
Ensembl chr11:68,030,617...68,036,644
JBrowse link
G NDUFV1 NADH:ubiquinone oxidoreductase core subunit V1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr11:67,606,936...67,612,554
Ensembl chr11:67,605,653...67,612,554
JBrowse link
G NME2 NME/NM23 nucleoside diphosphate kinase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr17:51,165,536...51,171,744
Ensembl chr17:51,165,435...51,171,744
Ensembl chr17:51,165,435...51,171,744
JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 3:193,593,149...193,697,811
Ensembl chr 3:193,593,144...193,697,811
JBrowse link
G P3H3 prolyl 3-hydroxylase 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr12:6,828,407...6,839,847
Ensembl chr12:6,828,407...6,839,847
JBrowse link
G PDCD6IP programmed cell death 6 interacting protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 3:33,798,630...33,869,703
Ensembl chr 3:33,798,571...33,869,707
JBrowse link
G PDHA1 pyruvate dehydrogenase E1 subunit alpha 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr  X:19,343,906...19,361,718
Ensembl chr  X:19,343,893...19,361,718
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO mRNA:increased expression:tibia (rat) RGD PMID:21864409 RGD:6771362 NCBI chr17:64,319,415...64,413,844
Ensembl chr17:64,319,415...64,413,776
JBrowse link
G PLCD1 phospholipase C delta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 3:38,007,496...38,029,642
Ensembl chr 3:38,007,496...38,029,642
Ensembl chr 3:38,007,496...38,029,642
JBrowse link
G PLOD2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 3:146,069,437...146,161,184
Ensembl chr 3:146,069,440...146,163,653
JBrowse link
G PLS3 plastin 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr  X:115,561,174...115,650,861
Ensembl chr  X:115,561,174...115,650,861
JBrowse link
G POMC proopiomelanocortin IMP RGD PMID:21378032 RGD:5508809 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903
JBrowse link
G POU3F3 POU class 3 homeobox 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 2:104,854,115...104,858,574
Ensembl chr 2:104,853,287...104,858,574
Ensembl chr 2:104,853,287...104,858,574
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PPP2R1A protein phosphatase 2 scaffold subunit Aalpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr19:52,190,052...52,229,518
Ensembl chr19:52,190,048...52,229,518
JBrowse link
G PSMB1 proteasome 20S subunit beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 6:170,535,120...170,553,307
Ensembl chr 6:170,535,120...170,553,307
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 susceptibility IAGP
EXP
DNA:SNP (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:32004530, PMID:15334463 RGD:1625347 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,423
JBrowse link
G RAN RAN, member RAS oncogene family EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr12:130,871,879...130,877,678
Ensembl chr12:130,872,037...130,877,678
JBrowse link
G RCN3 reticulocalbin 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr19:49,527,579...49,543,638
Ensembl chr19:49,528,003...49,546,962
JBrowse link
G RUNX2 RUNX family transcription factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349
JBrowse link
G S100A4 S100 calcium binding protein A4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16948116 NCBI chr 1:153,543,621...153,545,806
Ensembl chr 1:153,543,613...153,550,136
JBrowse link
G SCRN1 secernin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 7:29,920,103...29,990,289
Ensembl chr 7:29,920,104...29,990,289
JBrowse link
G SDCBP syndecan binding protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 8:58,553,261...58,582,860
Ensembl chr 8:58,552,924...58,582,859
JBrowse link
G SDHA succinate dehydrogenase complex flavoprotein subunit A EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 5:218,309...264,816
Ensembl chr 5:218,241...257,082
JBrowse link
G SEC23A Sec23 homolog A, COPII coat complex component EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr14:39,031,919...39,103,235
Ensembl chr14:39,031,919...39,109,646
JBrowse link
G SERPINA1 serpin family A member 1 IEP RGD PMID:20434574 RGD:2324964 NCBI chr14:94,376,747...94,390,654
Ensembl chr14:94,376,747...94,390,693
JBrowse link
G SGCG sarcoglycan gamma EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr13:23,160,508...23,325,162
Ensembl chr13:23,180,979...23,325,162
Ensembl chr13:23,180,979...23,325,162
JBrowse link
G SLC2A1 solute carrier family 2 member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18973239 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893
Ensembl chr 1:42,925,353...42,958,893
JBrowse link
G SMAD3 SMAD family member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21217753, PMID:22772368 NCBI chr15:67,065,602...67,195,195
Ensembl chr15:67,063,763...67,195,169
JBrowse link
G SOD2 superoxide dismutase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15292528, PMID:18784066, PMID:22108257 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
Ensembl chr 6:159,669,069...159,762,529
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G TENT5A terminal nucleotidyltransferase 5A susceptibility IAGP DNA:repeats: : RGD PMID:25231575 RGD:14390133 NCBI chr 6:81,745,730...81,752,681
Ensembl chr 6:81,491,439...81,752,774
JBrowse link
G TFPI2 tissue factor pathway inhibitor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr 7:93,885,396...93,890,753
Ensembl chr 7:93,885,396...93,890,753
JBrowse link
G TGFB1 transforming growth factor beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 ISS OMIM:140600 | OMIM:165720 | OMIM:607850 | OMIM:612400 MouseDO NCBI chr 9:99,104,038...99,154,192
Ensembl chr 9:99,104,038...99,154,192
JBrowse link
G TGM2 transglutaminase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr20:38,127,385...38,166,508
Ensembl chr20:38,127,385...38,166,578
JBrowse link
G TLR8 toll like receptor 8 IAGP ClinVar Annotator: match by term: Osteoarthritis ClinVar NCBI chr  X:12,906,620...12,923,169
Ensembl chr  X:12,906,620...12,923,169
JBrowse link
G TLR8-AS1 TLR8 antisense RNA 1 IAGP ClinVar Annotator: match by term: Osteoarthritis ClinVar NCBI chr  X:12,902,817...12,943,300
Ensembl chr  X:12,902,817...12,908,333
JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a ISO RGD PMID:14872496 RGD:2290500 NCBI chr 8:23,190,452...23,225,102
Ensembl chr 8:23,190,452...23,225,102
JBrowse link
G TNFRSF10B TNF receptor superfamily member 10b ISO RGD PMID:14872496 RGD:2290500 NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,031
JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b disease_progression IAGP RGD PMID:15334463 RGD:1625347 NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885
JBrowse link
G TNFSF10 TNF superfamily member 10 ISO RGD PMID:14872496 RGD:2290500 NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475
JBrowse link
G TNFSF15 TNF superfamily member 15 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chr 9:114,784,635...114,806,039
Ensembl chr 9:114,784,652...114,806,039
JBrowse link
G TRAP1 TNF receptor associated protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr16:3,658,037...3,717,524
Ensembl chr16:3,651,639...3,717,553
JBrowse link
G TRIM2 tripartite motif containing 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 4:153,152,163...153,339,317
Ensembl chr 4:153,152,163...153,339,319
Ensembl chr 4:153,152,163...153,339,319
JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21964574 NCBI chr12:109,783,087...109,833,398
Ensembl chr12:109,783,087...109,833,406
Ensembl chr12:109,783,087...109,833,406
JBrowse link
G TXNRD1 thioredoxin reductase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307
JBrowse link
G VDAC2 voltage dependent anion channel 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr10:75,210,170...75,231,448
Ensembl chr10:75,210,154...75,231,448
JBrowse link
G VIM vimentin EXP CTD Direct Evidence: marker/mechanism CTD PMID:16876394, PMID:18784066 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593
JBrowse link
G YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta EXP CTD Direct Evidence: marker/mechanism CTD PMID:18784066 NCBI chr 2:9,583,967...9,630,997
Ensembl chr 2:9,583,967...9,630,997
JBrowse link
Osteoarthritis with Mild Chondrodysplasia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL2A1 collagen type II alpha 1 chain IAGP ClinVar Annotator: match by term: NAMAQUALAND HIP DYSPLASIA
ClinVar Annotator: match by term: Osteoarthritis with mild chondrodysplasia
ClinVar
OMIM
PMID:1975693, PMID:1985108, PMID:7752132, PMID:7757086, PMID:8325895, PMID:8507190, PMID:9101290, PMID:9711874, PMID:25741868, PMID:28492532 NCBI chr12:47,972,967...48,006,212
Ensembl chr12:47,972,967...48,004,554
JBrowse link
Osteoarthritis, Experimental term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BECN1 beclin 1 treatment ISO RGD PMID:23589102 RGD:11561955 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
JBrowse link
G BMP4 bone morphogenetic protein 4 IDA RGD PMID:19404941 RGD:9068434 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:29621761 RGD:13782275 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CASP6 caspase 6 treatment ISO RGD PMID:29621761 RGD:13782275 NCBI chr 4:109,688,628...109,703,445
Ensembl chr 4:109,688,622...109,703,583
JBrowse link
G CASP7 caspase 7 treatment ISO RGD PMID:29621761 RGD:13782275 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
JBrowse link
G CASP8 caspase 8 treatment ISO RGD PMID:29621761 RGD:13782275 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,287,711
JBrowse link
G COL1A1 collagen type I alpha 1 chain treatment ISO RGD PMID:25128628 RGD:11041187 NCBI chr17:50,184,096...50,201,649
Ensembl chr17:50,183,289...50,201,632
Ensembl chr17:50,183,289...50,201,632
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 ISO RGD PMID:22833219 RGD:10402072 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 IDA RGD PMID:23041435 RGD:10402106 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145
JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A treatment ISO RGD PMID:16394269 RGD:10402538 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
JBrowse link
G LRPAP1 LDL receptor related protein associated protein 1 ISO mRNA:decreased expression:knee RGD PMID:24754147 RGD:10412054 NCBI chr 4:3,503,612...3,532,497
Ensembl chr 4:3,503,612...3,532,446
JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha treatment ISO RGD PMID:23589102 RGD:11561955 NCBI chr20:34,546,823...34,560,345
Ensembl chr20:34,546,854...34,560,345
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO RGD PMID:29364174 RGD:13800565 NCBI chr16:30,114,105...30,123,309
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G SERPINF1 serpin family F member 1 severity ISO RGD PMID:28122611 RGD:27226703 NCBI chr17:1,762,060...1,777,565
Ensembl chr17:1,762,029...1,777,565
JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 treatment ISO RGD PMID:23589102 RGD:11561955 NCBI chr12:131,894,622...131,923,150
Ensembl chr12:131,894,622...131,923,150
JBrowse link
Osteoarthritis, Hip term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 ISO mRNA:increased expression:cartilage RGD PMID:22670655 RGD:10043109 NCBI chr21:26,917,922...26,967,758
Ensembl chr21:26,917,922...26,967,088
JBrowse link
G ASPN asporin IEP
IAGP
mRNA:increased expression:cartilage:
DNA:repeats:exon:
RGD PMID:15640800, PMID:15640800 RGD:9684965, RGD:9684965 NCBI chr 9:92,456,205...92,482,506
Ensembl chr 9:92,456,205...92,482,506
JBrowse link
G ASTN2 astrotactin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr 9:116,423,112...117,415,057
Ensembl chr 9:116,425,225...117,415,070
JBrowse link
G CHADL chondroadherin like EXP CTD Direct Evidence: marker/mechanism CTD PMID:28319091, PMID:30374069 NCBI chr22:41,229,510...41,241,771
Ensembl chr22:41,229,510...41,240,931
JBrowse link
G COL10A1 collagen type X alpha 1 chain ISO mRNA, protein:increased expression:cartilage RGD PMID:22670655 RGD:10043109 NCBI chr 6:116,118,909...116,219,937
Ensembl chr 6:116,118,909...116,158,747
JBrowse link
G COL11A1 collagen type XI alpha 1 chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr 1:102,876,473...103,108,580
Ensembl chr 1:102,876,467...103,108,872
JBrowse link
G COL1A1 collagen type I alpha 1 chain no_association
susceptibility
IEP
IAGP
DNA:SNP:intron:g.2046G>T (human) RGD PMID:17187661, PMID:9811048, PMID:15880349 RGD:5688305, RGD:5688330, RGD:5688306 NCBI chr17:50,184,096...50,201,649
Ensembl chr17:50,183,289...50,201,632
Ensembl chr17:50,183,289...50,201,632
JBrowse link
G COMP cartilage oligomeric matrix protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:28319091 NCBI chr19:18,782,773...18,791,305
Ensembl chr19:18,782,773...18,791,305
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chr17:45,784,320...45,835,828
Ensembl chr17:45,784,280...45,835,828
JBrowse link
G DIABLO diablo IAP-binding mitochondrial protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chr12:122,207,662...122,227,456
Ensembl chr12:122,207,663...122,227,456
Ensembl chr12:122,207,663...122,227,456
JBrowse link
G ESR1 estrogen receptor 1 IAGP DNA:SNP:intron:g.-397T>C (human) RGD PMID:17419075 RGD:10045661 NCBI chr 6:151,654,148...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G FILIP1 filamin A interacting protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr 6:75,291,858...75,493,800
Ensembl chr 6:75,291,859...75,493,800
JBrowse link
G GDF5 growth differentiation factor 5 IAGP ClinVar Annotator: match by term: Osteoarthritis of hip ClinVar PMID:17384641 NCBI chr20:35,433,347...35,454,749
Ensembl chr20:35,433,347...35,454,746
JBrowse link
G GHR growth hormone receptor IAGP associated with Acromegaly;DNA:deletion:exon: RGD PMID:19864451 RGD:10003142 NCBI chr 5:42,423,439...42,721,878
Ensembl chr 5:42,423,439...42,721,878
JBrowse link
G HDAC9 histone deacetylase 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr 7:18,086,825...19,002,416
Ensembl chr 7:18,086,949...19,002,416
JBrowse link
G HFE homeostatic iron regulator EXP CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr 6:26,087,347...26,098,343
Ensembl chr 6:26,087,281...26,098,343
JBrowse link
G IL11 interleukin 11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30374069, PMID:30664745 NCBI chr19:55,364,382...55,370,463
Ensembl chr19:55,364,382...55,370,463
JBrowse link
G IL4R interleukin 4 receptor susceptibility
no_association
IAGP DNA:SNPs:multiple
DNA:missense mutations:cds:p.S411L, p.S727A (rs1805013, rs1805016) (human)
RGD PMID:14745651, PMID:19036616 RGD:10402782, RGD:10402784 NCBI chr16:27,313,668...27,364,778
Ensembl chr16:27,313,668...27,364,778
JBrowse link
G ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr 3:52,777,599...52,792,068
Ensembl chr 3:52,777,595...52,792,068
JBrowse link
G LMX1B LIM homeobox transcription factor 1 beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr 9:126,613,928...126,701,032
Ensembl chr 9:126,614,443...126,701,032
Ensembl chr 9:126,614,443...126,701,032
JBrowse link
G LOC109461476 GDF5 promoter region IAGP ClinVar Annotator: match by term: Osteoarthritis of hip ClinVar PMID:17384641 NCBI chr20:35,437,929...35,438,683 JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr11:65,538,559...65,558,389
Ensembl chr11:65,538,805...65,558,930
JBrowse link
G MAPT microtubule associated protein tau EXP CTD Direct Evidence: marker/mechanism CTD PMID:30664745 NCBI chr17:45,894,538...46,028,334
Ensembl chr17:45,894,551...46,028,334
Ensembl chr17:45,894,551...46,028,334
JBrowse link
G MMP13 matrix metallopeptidase 13 ISO mRNA, protein:increased expression:cartilage RGD PMID:22670655 RGD:10043109 NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732
JBrowse link
G RUNX2 RUNX family transcription factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349
JBrowse link
G SMAD3 SMAD family member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr15:67,065,602...67,195,195
Ensembl chr15:67,063,763...67,195,169
JBrowse link
G SMO smoothened, frizzled class receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr 7:129,188,633...129,213,548
Ensembl chr 7:129,188,633...129,213,545
JBrowse link
G TNC tenascin C EXP CTD Direct Evidence: marker/mechanism CTD PMID:30374069 NCBI chr 9:115,019,575...115,118,244
Ensembl chr 9:115,019,575...115,118,257
JBrowse link
Osteoarthritis, Temporomandibular Joint term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF6 activating transcription factor 6 ISO mRNA,protein:increased expression:chondrocyte RGD PMID:31007149 RGD:34888237 NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,320...161,964,070
JBrowse link
G BECN1 beclin 1 ISO RGD PMID:31007149 RGD:34888237 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
JBrowse link
G CASP12 caspase 12 (gene/pseudogene) ISO mRNA,protein:increased expression:chondrocyte RGD PMID:31007149 RGD:34888237 NCBI chr11:104,885,718...104,898,460
Ensembl chr11:104,885,718...104,898,670
JBrowse link
G DDIT3 DNA damage inducible transcript 3 ISO mRNA,protein:increased expression:chondrocyte RGD PMID:31007149 RGD:34888237 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO mRNA,protein:increased expression:chondrocyte RGD PMID:31007149 RGD:34888237 NCBI chr 2:88,556,741...88,627,464
Ensembl chr 2:88,556,741...88,627,464
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 ISO RGD PMID:31007149 RGD:34888237 NCBI chr17:64,039,142...64,132,469
Ensembl chr17:64,039,142...64,130,819
JBrowse link
G FAS Fas cell surface death receptor ISO mRNA:increased expression:mandibular condyle, cartilage (rat) RGD PMID:23934157 RGD:8663479 NCBI chr10:88,968,429...89,017,059
Ensembl chr10:88,990,531...89,017,059
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO mRNA,protein:increased expression:chondrocyte RGD PMID:31007149 RGD:34888237 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,343
JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta ISO RGD PMID:31007149 RGD:34888237 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779
JBrowse link
G RPS6 ribosomal protein S6 ISO RGD PMID:31007149 RGD:34888237 NCBI chr 9:19,375,715...19,380,236
Ensembl chr 9:19,375,715...19,380,236
JBrowse link
otulipenia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OTULIN OTU deubiquitinase with linear linkage specificity IAGP ClinVar Annotator: match by term: Autoinflammation, panniculitis, and dermatosis syndrome ClinVar
OMIM
PMID:27523608, PMID:27559085 NCBI chr 5:14,660,794...14,716,552
Ensembl chr 5:14,664,664...14,699,850
JBrowse link
polymyalgia rheumatica term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRH corticotropin releasing hormone no_association IAGP DNA:polymorphism:promoter RGD PMID:12051390 RGD:1581301 NCBI chr 8:66,176,376...66,178,464
Ensembl chr 8:66,176,376...66,178,464
JBrowse link
G CRP C-reactive protein treatment IEP RGD PMID:2859021 RGD:9495925 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G HFE homeostatic iron regulator IAGP DNA:missense mutation: :p.C282Y (rs1800562) (human) RGD PMID:30657865 RGD:14746966 NCBI chr 6:26,087,347...26,098,343
Ensembl chr 6:26,087,281...26,098,343
JBrowse link
G MBL2 mannose binding lectin 2 IAGP DNA:polymorphism:cds: RGD PMID:12375325 RGD:8693752 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784
JBrowse link
G MMP3 matrix metallopeptidase 3 IEP RGD PMID:11796404 RGD:7241254 NCBI chr11:102,835,801...102,843,609
Ensembl chr11:102,835,801...102,843,609
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 IEP protein:increased expression:plasma, endothelial microparticle (human) RGD PMID:22211720 RGD:6771319 NCBI chr17:64,319,415...64,413,844
Ensembl chr17:64,319,415...64,413,776
JBrowse link
Reynolds Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LBR lamin B receptor IAGP ClinVar Annotator: match by term: Reynolds syndrome OMIM
ClinVar
PMID:20522425, PMID:25741868 NCBI chr 1:225,401,502...225,428,821
Ensembl chr 1:225,401,502...225,428,925
JBrowse link
rheumatic fever term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GC GC vitamin D binding protein IAGP RGD PMID:2737695 RGD:5509933 NCBI chr 4:71,741,693...71,805,520
Ensembl chr 4:71,741,696...71,804,041
JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 IAGP DNA:polymorphisms, haplotypes:multiple RGD PMID:17559688 RGD:5147792 NCBI chr 6:32,637,406...32,654,846
Ensembl chr 6:32,628,179...32,647,062
JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 IAGP DNA:polymorphisms, haplotypes:multiple RGD PMID:17559688 RGD:5147792 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383
JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 IAGP DNA:polymorphisms, haplotypes:multiple RGD PMID:17559688 RGD:5147792 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,578,769...32,589,848
JBrowse link
G ICAM1 intercellular adhesion molecule 1 IEP protein:increased expression:serum RGD PMID:14567831 RGD:13702910 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
rheumatic heart disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD36 CD36 molecule IEP mRNA:decreased expression:blood, mononuclear cell RGD PMID:16741676 RGD:6893529 NCBI chr 7:80,602,207...80,679,277
Ensembl chr 7:80,369,575...80,679,277
JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase ISO RGD PMID:26823728 RGD:13792679 NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374
JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 IAGP DNA:polymorphisms, haplotypes:multiple RGD PMID:17559688 RGD:5147792 NCBI chr 6:32,637,406...32,654,846
Ensembl chr 6:32,628,179...32,647,062
JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 IAGP DNA:polymorphisms:cds:HLA-DQB1*08 (human) RGD PMID:17578051 RGD:5147630 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383
JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 susceptibility IAGP DNA:polymorphism (human)
DNA:polymorphism:cds:HLA-DRB1*13 (human)
RGD PMID:17578051, PMID:16426242 RGD:5147630, RGD:5147643 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,578,769...32,589,848
JBrowse link
G IGF1 insulin like growth factor 1 IEP RGD PMID:16406300 RGD:1582623 NCBI chr12:102,395,860...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G IL10 interleukin 10 no_association IAGP RGD PMID:16043936 RGD:1598626 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G MMP9 matrix metallopeptidase 9 IEP RGD PMID:16406300 RGD:1582623 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
rheumatic myocarditis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ICAM1 intercellular adhesion molecule 1 severity IEP protein:increased expression:serum RGD PMID:22987107 RGD:13702907 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G SELE selectin E severity IEP protein:increased expression:serum RGD PMID:22987107 RGD:13702907 NCBI chr 1:169,722,640...169,734,079
Ensembl chr 1:169,722,640...169,764,705
JBrowse link
G VCAM1 vascular cell adhesion molecule 1 severity IEP protein:increased expression:serum RGD PMID:22987107 RGD:13702907 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
JBrowse link
rheumatoid arthritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2M alpha-2-macroglobulin IEA GAD PMID:15118671 RGD:1331525 NCBI chr12:9,067,708...9,116,229
Ensembl chr12:9,067,664...9,116,229
JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20080907, PMID:22104130 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr10:99,782,602...99,853,741
Ensembl chr10:99,782,640...99,852,594
JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr17:50,634,881...50,692,253
Ensembl chr17:50,634,777...50,692,253
JBrowse link
G ABCC4 ATP binding cassette subfamily C member 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475
JBrowse link
G ABCC5 ATP binding cassette subfamily C member 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr 3:183,919,934...184,018,010
Ensembl chr 3:183,919,934...184,017,939
JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (Junior blood group) EXP CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
JBrowse link
G ACAN aggrecan disease_progression IEP
EXP
protein:increased degradation:cartilage
CTD Direct Evidence: marker/mechanism
CTD PMID:15292528, PMID:16507130 RGD:11570537 NCBI chr15:88,803,436...88,875,353
Ensembl chr15:88,803,436...88,875,354
Ensembl chr15:88,803,436...88,875,354
JBrowse link
G ACKR3 atypical chemokine receptor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 2:236,537,131...236,582,358
Ensembl chr 2:236,567,787...236,582,354
JBrowse link
G ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif 4 IEP mRNA:increased expression:synovium RGD PMID:11801682 RGD:10043106 NCBI chr 1:161,184,302...161,202,339
Ensembl chr 1:161,184,302...161,199,054
JBrowse link
G ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 IEP protein:alternative form:synovium RGD PMID:11801682 RGD:10043106 NCBI chr21:26,917,922...26,967,758
Ensembl chr21:26,917,922...26,967,088
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing IEP
EXP
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
CTD PMID:12833524, PMID:21789720 RGD:5686424 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
JBrowse link
G ADORA2A adenosine A2a receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357
JBrowse link
G ADRB3 adrenoceptor beta 3 IAGP DNA:missense mutation:cds:p.W64R rs4994 (human) RGD PMID:12739037 RGD:5684893 NCBI chr 8:37,962,990...37,966,599
Ensembl chr 8:37,962,990...37,966,599
JBrowse link
G AFF3 AF4/FMR2 family member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20453842, PMID:23143596 NCBI chr 2:99,545,419...100,142,590
Ensembl chr 2:99,545,419...100,192,428
JBrowse link
G AGER advanced glycosylation end-product specific receptor IEP
EXP
protein:decreased expression:plasma (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:16385501, PMID:20541603 RGD:7244141 NCBI chr 6:32,180,969...32,184,380
Ensembl chr 6:32,180,968...32,184,322
JBrowse link
G AHR aryl hydrocarbon receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:18617548 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
JBrowse link
G ALOX5 arachidonate 5-lipoxygenase EXP CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr10:45,374,209...45,446,121
Ensembl chr10:45,374,176...45,446,119
JBrowse link
G ANG angiogenin IEP RGD PMID:12653852 RGD:6892721 NCBI chr14:20,684,177...20,694,186
Ensembl chr14:20,684,177...20,698,971
JBrowse link
G ANKRD55 ankyrin repeat domain 55 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 5:56,099,680...56,233,330
Ensembl chr 5:56,099,680...56,233,330
JBrowse link
G ANXA3 annexin A3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr 4:78,551,761...78,610,447
Ensembl chr 4:78,551,747...78,610,451
JBrowse link
G AP4B1-AS1 AP4B1 antisense RNA 1 IAGP ClinVar Annotator: match by term: Rheumatoid arthritis ClinVar PMID:15004560, PMID:15208781, PMID:15273934, PMID:15580548, PMID:15719322, PMID:15744042, PMID:16273109, PMID:16339849, PMID:16470599, PMID:17170052, PMID:17436241, PMID:17554300, PMID:17878369, PMID:18301444, PMID:18978792, PMID:19265110, PMID:19430480, PMID:19898480, PMID:21841778, PMID:28492532 NCBI chr 1:113,812,612...113,901,237
Ensembl chr 1:113,856,635...113,901,237
JBrowse link
G APOA4 apolipoprotein A4 IEP protein:increased expression:blood serum (human) RGD PMID:20367977 RGD:5685646 NCBI chr11:116,820,700...116,823,304
Ensembl chr11:116,820,700...116,823,304
JBrowse link
G ARID5B AT-rich interaction domain 5B EXP CTD Direct Evidence: marker/mechanism CTD PMID:22446963, PMID:23143596 NCBI chr10:61,901,254...62,096,944
Ensembl chr10:61,901,684...62,096,944
JBrowse link
G ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase EXP CTD Direct Evidence: marker/mechanism CTD PMID:19193698 NCBI chr 2:215,311,974...215,359,745
Ensembl chr 2:215,311,956...215,349,773
JBrowse link
G B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr 2:62,196,115...62,224,731
Ensembl chr 2:62,196,115...62,224,731
JBrowse link
G B3GNT9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr16:67,148,104...67,150,998
Ensembl chr16:67,148,104...67,150,998
JBrowse link
G BAIAP2L1 BAR/IMD domain containing adaptor protein 2 like 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 7:98,291,650...98,401,090
Ensembl chr 7:98,291,650...98,401,090
JBrowse link
G BCL2A1 BCL2 related protein A1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr15:79,960,892...79,971,196
Ensembl chr15:79,960,892...79,971,196
JBrowse link
G BDKRB2 bradykinin receptor B2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein IDA
IEP
protein:increased expression:serum RGD PMID:22447331, PMID:3488088 RGD:6483593, RGD:6483600 NCBI chr 1:156,242,184...156,243,317
Ensembl chr 1:156,242,184...156,243,317
JBrowse link
G BGN biglycan EXP CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr  X:153,494,980...153,509,546
Ensembl chr  X:153,494,980...153,509,546
JBrowse link
G BLK BLK proto-oncogene, Src family tyrosine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:20453842, PMID:23143596 NCBI chr 8:11,493,991...11,564,599
Ensembl chr 8:11,486,894...11,564,599
JBrowse link
G BMP4 bone morphogenetic protein 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
JBrowse link
G BMP6 bone morphogenetic protein 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728
JBrowse link
G BTNL2 butyrophilin like 2 susceptibility IAGP DNA:SNPs: : RGD PMID:23364395 RGD:9685033 NCBI chr 6:32,393,339...32,408,879
Ensembl chr 6:32,393,963...32,407,128
JBrowse link
G C3 complement C3 IEP RGD PMID:7561187 RGD:11040775 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G C4B complement C4B (Chido blood group) IAGP RGD PMID:22076784 RGD:5688263 NCBI chr 6:32,014,795...32,035,418
Ensembl chr 6:32,014,795...32,035,418
JBrowse link
G CALD1 caldesmon 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr 7:134,779,629...134,970,729
Ensembl chr 7:134,744,252...134,970,729
JBrowse link
G CASP7 caspase 7 IEP RGD PMID:18785314 RGD:5684540 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
JBrowse link
G CAST calpastatin IDA RGD PMID:7706496 RGD:5683620 NCBI chr 5:96,662,037...96,774,683
Ensembl chr 5:96,525,267...96,779,595
JBrowse link
G CAT catalase EXP CTD Direct Evidence: marker/mechanism CTD PMID:22450443 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CAV2 caveolin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr 7:116,499,738...116,508,541
Ensembl chr 7:116,287,380...116,508,541
JBrowse link
G CCL2 C-C motif chemokine ligand 2 IEP protein:increased expression:serum RGD PMID:20056091 RGD:4891442 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,218...34,257,203
JBrowse link
G CCL21 C-C motif chemokine ligand 21 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18794853, PMID:20453842, PMID:23143596 NCBI chr 9:34,709,005...34,710,136
Ensembl chr 9:34,709,005...34,710,136
JBrowse link
G CCL22 C-C motif chemokine ligand 22 IEP protein:increased expression:plasma: RGD PMID:19942450 RGD:10054497 NCBI chr16:57,358,783...57,366,189
Ensembl chr16:57,358,783...57,366,189
JBrowse link
G CCL8 C-C motif chemokine ligand 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr17:34,319,435...34,321,402
Ensembl chr17:34,319,435...34,321,402
JBrowse link
G CCN1 cellular communication network factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589
Ensembl chr 1:85,580,761...85,584,589
JBrowse link
G CCN2 cellular communication network factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372
JBrowse link
G CCR1 C-C motif chemokine receptor 1 IMP RGD PMID:12860725 RGD:5688170 NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313
JBrowse link
G CCR3 C-C motif chemokine receptor 3 IEP protein:increased expression:synovial fluid, neutrophil RGD PMID:19017998 RGD:4145632 NCBI chr 3:46,210,699...46,266,706
Ensembl chr 3:46,163,604...46,266,706
JBrowse link
G CCR4 C-C motif chemokine receptor 4 IEP protein:increased expression:synovial membrane:
mRNA:increased expression:synovium:
RGD PMID:19942450, PMID:25430645 RGD:10054497, RGD:10054499 NCBI chr 3:32,951,555...32,956,349
Ensembl chr 3:32,951,644...32,956,349
JBrowse link
G CCR5 C-C motif chemokine receptor 5 resistance
no_association
IAGP DNA:frameshift mutation:cds:p.S185_T195del rs333 (human) RGD PMID:16541097, PMID:17565662 RGD:1626290, RGD:1626283 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,854...46,376,206
JBrowse link
G CCR6 C-C motif chemokine receptor 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20453841, PMID:20453842, PMID:23143596 NCBI chr 6:167,111,795...167,139,141
Ensembl chr 6:167,111,807...167,139,696
JBrowse link
G CD2 CD2 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 1:116,754,430...116,769,229
Ensembl chr 1:116,754,430...116,769,229
JBrowse link
G CD244 CD244 molecule susceptibility IAGP
EXP
ClinVar Annotator: match by term: Rheumatoid arthritis
CTD Direct Evidence: marker/mechanism
ClinVar
OMIM
CTD
PMID:18794858 NCBI chr 1:160,830,160...160,862,892
Ensembl chr 1:160,830,160...160,862,887
JBrowse link
G CD28 CD28 molecule IEP
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:19898481, PMID:20453842, PMID:23143596, PMID:19075187 RGD:5131619 NCBI chr 2:203,706,509...203,739,756
Ensembl chr 2:203,706,475...203,738,912
JBrowse link
G CD3E CD3e molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr11:118,304,730...118,316,173
Ensembl chr11:118,304,730...118,316,175
Ensembl chr11:118,304,730...118,316,175
JBrowse link
G CD40 CD40 molecule IAGP
EXP
DNA:SNP: :rs4810485 (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:18794853, PMID:20453842, PMID:23143596, PMID:20498205 RGD:5490972 NCBI chr20:46,118,242...46,129,858
Ensembl chr20:46,118,278...46,129,863
JBrowse link
G CD5 CD5 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr11:61,093,963...61,127,852
Ensembl chr11:61,102,489...61,127,852
JBrowse link
G CD80 CD80 molecule IEP protein:increased expression:serum RGD PMID:22917707 RGD:6893647 NCBI chr 3:119,524,293...119,559,614
Ensembl chr 3:119,524,293...119,559,614
JBrowse link
G CD83 CD83 molecule EXP CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr 6:14,117,256...14,136,918
Ensembl chr 6:14,117,256...14,136,918
JBrowse link
G CDK6 cyclin dependent kinase 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18794853 NCBI chr 7:92,604,921...92,836,573
Ensembl chr 7:92,604,921...92,836,594
Ensembl chr 7:92,604,921...92,836,594
JBrowse link
G CEBPB CCAAT enhancer binding protein beta IEP protein:increased expression:knee, articular cartilage (human) RGD PMID:19248099 RGD:10401213 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668
JBrowse link
G CHI3L1 chitinase 3 like 1 severity IEP protein:increased secretion:serum (human) RGD PMID:10461474 RGD:4892605 NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704
JBrowse link
G CIITA class II major histocompatibility complex transactivator susceptibility
no_association
IAGP
EXP
DNA:haplotype:promoter/CDS:rs3087456G/rs4774C
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Rheumatoid arthritis
DNA:polymorphism:promoter:-168A>G
DNA:polymorphism:promoter:rs3087456, no association in a German cohort
CTD
OMIM
ClinVar
PMID:15821736, PMID:16849401, PMID:19221398, PMID:15821736, PMID:16426246 RGD:5491176, RGD:1358146, RGD:5491189 NCBI chr16:10,866,208...10,941,562
Ensembl chr16:10,866,222...10,943,021
JBrowse link
G CLEC12A C-type lectin domain family 12 member A EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr12:9,951,268...9,995,209
Ensembl chr12:9,951,316...9,995,694
JBrowse link
G CLEC16A C-type lectin domain containing 16A IAGP DNA:polymorphism:intron:rs6498169G RGD PMID:19221398 RGD:5491176 NCBI chr16:10,944,539...11,193,272
Ensembl chr16:10,944,564...11,182,186
JBrowse link
G COL2A1 collagen type II alpha 1 chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:27028940, PMID:29935983 NCBI chr12:47,972,967...48,006,212
Ensembl chr12:47,972,967...48,004,554
JBrowse link
G CP ceruloplasmin EXP CTD Direct Evidence: marker/mechanism CTD PMID:26001728 NCBI chr 3:149,162,410...149,222,008
Ensembl chr 3:149,162,410...149,221,829
JBrowse link
G CRP C-reactive protein IEP
EXP
ISO
protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
CTD PMID:1568518, PMID:22173958, PMID:22173958 RGD:6904209, RGD:6904209 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
JBrowse link
G CSF2 colony stimulating factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22446963 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170
JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20453842, PMID:23143596 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,867,771...203,873,965
JBrowse link
G CTSD cathepsin D EXP CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,755...1,764,573
JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 IEP RGD PMID:11465708 RGD:4892002 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044
JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15292528 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17379860, PMID:19192274 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,541...73,743,716
JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 IEP protein:increased expression:synovial fluid, neutrophil RGD PMID:19017998 RGD:4145632 NCBI chr  X:71,615,913...71,618,515
Ensembl chr  X:71,615,916...71,618,511
JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,118,149
JBrowse link
G DDIT4 DNA damage inducible transcript 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,924...72,276,036
JBrowse link
G DDX6 DEAD-box helicase 6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr11:118,747,763...118,791,696
Ensembl chr11:118,747,763...118,791,164
JBrowse link
G DHFR dihydrofolate reductase EXP CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr 5:80,626,226...80,654,983
Ensembl chr 5:80,626,226...80,654,983
JBrowse link
G DNASE1L3 deoxyribonuclease 1 like 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596, PMID:30224649 NCBI chr 3:58,192,257...58,210,972
Ensembl chr 3:58,192,257...58,214,697
JBrowse link
G DNASE2 deoxyribonuclease 2, lysosomal ISS OMIM:180300 MouseDO NCBI chr19:12,875,209...12,881,449
Ensembl chr19:12,875,209...12,881,466
JBrowse link
G DNMT1 DNA methyltransferase 1 severity IEP mRNA:increased expression:mononuclear cell RGD PMID:20937307 RGD:9588623 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,345...10,231,286
JBrowse link
G DNMT3B DNA methyltransferase 3 beta disease_progression IAGP DNA:polymorphism:promoter:-283C>T(human) RGD PMID:19777235 RGD:9589110 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,356
JBrowse link
G EDN1 endothelin 1 treatment IDA RGD PMID:22249931 RGD:8661695 NCBI chr 6:12,256,463...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G ELN elastin IDA RGD PMID:12643515 RGD:9585739 NCBI chr 7:74,027,772...74,069,907
Ensembl chr 7:74,027,789...74,069,907
JBrowse link
G ENO1 enolase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19898480 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190
JBrowse link
G EPAS1 endothelial PAS domain protein 1 IEP protein:increased expression:layer of synovial tissue, stromal cell RGD PMID:12823854 RGD:10395366 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697
JBrowse link
G ESR2 estrogen receptor 2 severity IAGP DNA:SNP:exon:rs1256049(human) RGD PMID:21523342 RGD:5508794 NCBI chr14:64,226,707...64,338,631
Ensembl chr14:64,084,232...64,338,112
JBrowse link
G F2 coagulation factor II, thrombin EXP CTD Direct Evidence: marker/mechanism CTD PMID:26001728 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
Ensembl chr11:46,719,196...46,739,506
JBrowse link
G FAS Fas cell surface death receptor susceptibility IAGP
IMP
IEP
DNA:snp:promoter:g.-670A>G (human)
protein:increased expression:serum (human)
RGD PMID:23053964, PMID:20875116, PMID:12148596 RGD:8662433, RGD:12903969, RGD:8662455 NCBI chr10:88,968,429...89,017,059
Ensembl chr10:88,990,531...89,017,059
JBrowse link
G FASLG Fas ligand EXP CTD Direct Evidence: marker/mechanism CTD PMID:20008919 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
JBrowse link
G FCGR1A Fc fragment of IgG receptor Ia IEP protein:increased expression:synovial joint: RGD PMID:16670289 RGD:9685708 NCBI chr 1:149,782,694...149,800,609
Ensembl chr 1:149,782,671...149,792,518
JBrowse link
G FCGR2A Fc fragment of IgG receptor IIa IAGP
EXP
IDA
DNA:polymorphism: :p.H131R (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:20453842, PMID:23143596, PMID:12508778, PMID:8254199 RGD:5147978, RGD:5147984 NCBI chr 1:161,505,430...161,524,048
Ensembl chr 1:161,505,430...161,524,013
JBrowse link
G FCGR3A Fc fragment of IgG receptor IIIa susceptibility IAGP
IEP
DNA:polymorphism:exon:p.F158V(rs396991)(human)
DNA:CNVs
protein:decreased expression:NK cell
RGD PMID:19019892, PMID:25154742, PMID:15334114 RGD:5508391, RGD:11344974, RGD:5508467 NCBI chr 1:161,541,759...161,550,737
Ensembl chr 1:161,541,759...161,550,737
JBrowse link
G FKBP5 FKBP prolyl isomerase 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 6:35,573,590...35,728,583
Ensembl chr 6:35,573,585...35,728,583
JBrowse link
G FOXO3 forkhead box O3 IEP mRNA,protein:increased expression:peripheral blood mononuclear cell, polymorphonuclear cell,synovium: RGD PMID:19435720 RGD:10402186 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774
JBrowse link
G FOXP3 forkhead box P3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20476861 NCBI chr  X:49,250,436...49,264,932
Ensembl chr  X:49,250,438...49,270,477
Ensembl chr  X:49,250,438...49,270,477
JBrowse link
G FPGS folylpolyglutamate synthase EXP CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr 9:127,802,858...127,814,520
Ensembl chr 9:127,794,597...127,814,327
JBrowse link
G GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase EXP CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr21:33,503,931...33,542,892
Ensembl chr21:33,503,931...33,543,491
JBrowse link
G GATA3 GATA binding protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr10:8,045,420...8,075,198
Ensembl chr10:8,045,378...8,075,198
JBrowse link
G GC GC vitamin D binding protein IEP
EXP
protein:decreased expression:plasma
CTD Direct Evidence: marker/mechanism
CTD PMID:3874814, PMID:9548303 RGD:5509931 NCBI chr 4:71,741,693...71,805,520
Ensembl chr 4:71,741,696...71,804,041
JBrowse link
G GDF5 growth differentiation factor 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18830904 NCBI chr20:35,433,347...35,454,749
Ensembl chr20:35,433,347...35,454,746
JBrowse link
G GGH gamma-glutamyl hydrolase EXP CTD Direct Evidence: marker/mechanism CTD PMID:23897011 NCBI chr 8:63,015,079...63,038,806
Ensembl chr 8:63,015,079...63,038,806
JBrowse link
G GIN1 gypsy retrotransposon integrase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr 5:103,086,000...103,120,149
Ensembl chr 5:103,086,000...103,120,138
JBrowse link
G GPRC5A G protein-coupled receptor class C group 5 member A EXP CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr12:12,891,562...12,917,937
Ensembl chr12:12,890,782...12,917,937
Ensembl chr12:12,890,782...12,917,937
JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO
EXP
IEP
DNA: deletion: : heterozygous
CTD Direct Evidence: marker/mechanism
protein: decreased expression: mononuclear leukocytes
CTD PMID:10094932, PMID:18662895, PMID:10094932 RGD:5688373, RGD:5688380 NCBI chr11:67,266,420...67,286,556
Ensembl chr11:67,266,473...67,286,556
JBrowse link
G GRK5 G protein-coupled receptor kinase 5 no_association ISO
IEP
DNA: deletion::GRK2 and GRK6 deletions resulted in more severe arthritis
protein: : mononuclear blood cells
RGD PMID:18662895, PMID:10094932 RGD:5688373, RGD:5688380 NCBI chr10:119,207,571...119,459,745
Ensembl chr10:119,207,571...119,459,745
JBrowse link
G GRK6 G protein-coupled receptor kinase 6 ISO
EXP
IEP
DNA: deletion: : homozygous
CTD Direct Evidence: marker/mechanism
protein: decreased expression: mononuclear leukocytes
CTD PMID:10094932, PMID:18662895, PMID:10094932 RGD:5688373, RGD:5688380 NCBI chr 5:177,426,496...177,442,891
Ensembl chr 5:177,403,204...177,442,901
JBrowse link
G GSDME gasdermin E EXP CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr 7:24,698,355...24,762,235
Ensembl chr 7:24,698,355...24,757,940
JBrowse link
G GSTM1 glutathione S-transferase mu 1 susceptibility IAGP DNA:deletion: :
DNA:deletion: :
RGD PMID:16887863, PMID:15940757, PMID:16870093 RGD:5490993, RGD:5490998, RGD:5490994 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTT1 glutathione S-transferase theta 1 severity
susceptibility
IAGP DNA:deletion: : RGD PMID:19473562, PMID:20401725, PMID:20597111 RGD:5490553, RGD:5490983, RGD:5490982
G HAPLN1 hyaluronan and proteoglycan link protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 5:83,637,805...83,721,210
Ensembl chr 5:83,637,805...83,720,855
JBrowse link
G HCLS1 hematopoietic cell-specific Lyn substrate 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12833524 NCBI chr 3:121,631,399...121,660,903
Ensembl chr 3:121,631,399...121,660,927
JBrowse link
G HDAC1 histone deacetylase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:32289289 NCBI chr 1:32,292,083...32,333,628
Ensembl chr 1:32,292,083...32,333,635
JBrowse link
G HFE homeostatic iron regulator IAGP DNA:missense mutation: :p.C282Y (rs1800562) (human) RGD PMID:30651232 RGD:14746965 NCBI chr 6:26,087,347...26,098,343
Ensembl chr 6:26,087,281...26,098,343
JBrowse link
G HGF hepatocyte growth factor disease_progression IEP protein:increased expression:serum: RGD PMID:24387171 RGD:8548659 NCBI chr 7:81,699,006...81,770,438
Ensembl chr 7:81,699,010...81,770,438
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha IEP protein:increased expression:layer of synovial tissue, stromal cell RGD PMID:12823854 RGD:10395366 NCBI chr14:61,695,513...61,748,259
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17956852, PMID:22286218 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,990...33,089,696
JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 IAGP DNA:polymorphisms (human)
DNA:polymorphism (human)
RGD PMID:11482129, PMID:11454644 RGD:5147859, RGD:5147860 NCBI chr 6:32,637,406...32,654,846
Ensembl chr 6:32,628,179...32,647,062
JBrowse link
G HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 6:32,741,391...32,747,198
Ensembl chr 6:32,741,391...32,747,198
JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 IAGP DNA:polymorphism (human) RGD PMID:11454644 RGD:5147860 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383
JBrowse link
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 susceptibility IAGP
EXP
CTD Direct Evidence: marker/mechanism
DNA:polymorphism (human)
DNA:polymorphisms (human)
DNA:polymorphisms: :multiple (human)
CTD PMID:19898480, PMID:20453842, PMID:22286218, PMID:18512783, PMID:11454644, PMID:19117368, PMID:21246357 RGD:4144826, RGD:5147860, RGD:5147616, RGD:5147567 NCBI chr 6:32,578,775...32,589,848
Ensembl chr 6:32,578,769...32,589,848
JBrowse link
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 severity ISO RGD PMID:18025202 RGD:9685481 NCBI chr 7:26,189,920...26,200,775
Ensembl chr 7:26,173,057...26,201,529
JBrowse link
G HOXD10 homeobox D10 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 2:176,116,778...176,119,937
Ensembl chr 2:176,108,790...176,119,942
Ensembl chr 2:176,108,790...176,119,942
JBrowse link
G HOXD11 homeobox D11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 2:176,107,280...176,109,754
Ensembl chr 2:176,104,216...176,109,754
JBrowse link
G HOXD13 homeobox D13 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17568789 NCBI chr 2:176,087,487...176,095,944
Ensembl chr 2:176,092,721...176,095,944
JBrowse link
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr 1:209,686,179...209,734,929
Ensembl chr 1:209,686,178...209,734,949
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 IEP mRNA:increased expression:peripheral blood leukocyte: RGD PMID:21417552 RGD:10402843 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,738...102,139,699
Ensembl chr14:102,080,738...102,139,699
JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 IEP protein:increased expression:peripheral blood lymphocyte (human) RGD PMID:22047640 RGD:5688784 NCBI chr 5:133,052,013...133,106,449
Ensembl chr 5:133,052,013...133,106,449
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 IEP protein:increased expression:synovial joint RGD PMID:11315915 RGD:5685639 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,343
JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 IEP protein:increased expression:synovial cell: RGD PMID:23739258 RGD:10402561 NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,416
JBrowse link
G HSPB1 heat shock protein family B (small) member 1 IEP protein:increased expression:serum: RGD PMID:21417552 RGD:10402843 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295
JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 IEP mRNA:increased expression:peripheral blood leukocyte: RGD PMID:21417552 RGD:10402843 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737
JBrowse link
G IFNG interferon gamma treatment IDA
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:22450443, PMID:1417133 RGD:8157623 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IGF2 insulin like growth factor 2 IAGP
IEP
DNA:loss of imprinting:synovial cell
protein:decreased expression:plasma
RGD PMID:19556211, PMID:11247331 RGD:5510001, RGD:5510014 NCBI chr11:2,129,112...2,149,603
Ensembl chr11:2,129,112...2,141,238
JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17379860 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874
JBrowse link
G IKZF3 IKAROS family zinc finger 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23143596 NCBI chr17:39,757,715...39,864,312
Ensembl chr17:39,757,718...39,864,312
JBrowse link
G IL10 interleukin 10 susceptibility IAGP
EXP
ClinVar Annotator: match by term: Rheumatoid arthritis, progression of
CTD Direct Evidence: marker/mechanism
ClinVar
OMIM
CTD
PMID:12847677, PMID:22450443 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL13 interleukin 13 IEP protein:increased expression:serum RGD PMID:12051401 RGD:8549582 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
JBrowse link
G IL17A interleukin 17A treatment IMP RGD PMID:20926833 RGD:9068415 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638
JBrowse link
G IL18 interleukin 18 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16368150 NCBI chr11:112,143,251...112,164,104
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G IL19 interleukin 19 IAGP ClinVar Annotator: match by term: Rheumatoid arthritis, progression of ClinVar PMID:12847677 NCBI chr 1:206,770,773...206,842,981
Ensembl chr 1:206,770,764...206,842,981
JBrowse link
G IL1A interleukin 1 alpha severity IDA
IEP
associated with lung disease, interstitial
protein:increased expression:plasma, synovial fluid
RGD PMID:11192540, PMID:8162643 RGD:4142818, RGD:7794716 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta IEP
EXP
protein:decreased expression:serum
CTD Direct Evidence: marker/mechanism
CTD PMID:12566094, PMID:17379860, PMID:22450443, PMID:22414257 RGD:6482656 NCBI chr 2:112,829,751...112,836,843
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL1RN interleukin 1 receptor antagonist IDA
EXP
ISO
CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:7706905, PMID:19192274, PMID:19447938, PMID:10637275 RGD:7174696, RGD:8549810 NCBI chr 2:113,099,365...113,134,016
Ensembl chr 2:113,107,214...113,134,016
JBrowse link
G IL2 interleukin 2 IDA RGD PMID:6421522 RGD:8662948 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
JBrowse link
G IL20 interleukin 20 IEP RGD PMID:16947773 RGD:5147395 NCBI chr 1:206,863,565...206,869,223
Ensembl chr 1:206,865,354...206,869,223
JBrowse link
G IL21R interleukin 21 receptor ISO RGD PMID:19342640 RGD:6892964 NCBI chr16:27,402,162...27,452,043
Ensembl chr16:27,402,174...27,452,042
JBrowse link
G IL23A interleukin 23 subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:19192274 NCBI chr12:56,334,159...56,340,410
Ensembl chr12:56,334,174...56,340,410
JBrowse link
G IL23R interleukin 23 receptor susceptibility IAGP DNA:SNP::rs1343151(human) RGD PMID:18647855 RGD:8549596 NCBI chr 1:67,138,639...67,259,979
Ensembl chr 1:67,138,907...67,259,979
JBrowse link
G IL2RA interleukin 2 receptor subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:20453842, PMID:20476861, PMID:23143596 NCBI chr10:6,010,689...6,062,367
Ensembl chr10:6,010,689...6,062,370
JBrowse link
G IL2RB interleukin 2 receptor subunit beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:20453842, PMID:23143596 NCBI chr22:37,125,838...37,175,118
Ensembl chr22:37,125,843...37,175,054
JBrowse link
G IL3 interleukin 3 IAGP DNA: SNPs: Multiple: gene-gene interaction RGD PMID:20018070 RGD:5686905 NCBI chr 5:132,060,655...132,063,204
Ensembl chr 5:132,060,655...132,063,204
JBrowse link
G IL4R interleukin 4 receptor severity IAGP DNA:SNP: :rs1805010 (human) RGD PMID:24782180 RGD:10402783 NCBI chr16:27,313,668...27,364,778
Ensembl chr16:27,313,668...27,364,778
JBrowse link
G IL5 interleukin 5