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ONTOLOGY REPORT - ANNOTATIONS


Term:neuroendocrine carcinoma
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Accession:DOID:1800 term browser browse the term
Definition:A group of carcinomas which share a characteristic morphology, often being composed of clusters and trabecular sheets of round 'blue cells', granular chromatin, and an attenuated rim of poorly demarcated cytoplasm. Neuroendocrine tumors include carcinoids, small ('oat') cell carcinomas, medullary carcinoma of the thyroid, Merkel cell tumor, cutaneous neuroendocrine carcinoma, pancreatic islet cell tumors, and pheochromocytoma. Neurosecretory granules are found within the tumor cells. (Segen, Dictionary of Modern Medicine, 1992)
Synonyms:exact_synonym: Neuroendocrine Carcinomas
 primary_id: MESH:D018278;   RDO:0005361
 xref: NCI:C3773
For additional species annotation, visit the Alliance of Genome Resources.


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neuroendocrine carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eno2 enolase 2 JBrowse link 4 157,285,192 157,294,090 RGD:2293735
familial medullary thyroid carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Insrr insulin receptor-related receptor JBrowse link 2 187,161,817 187,181,400 RGD:8554872
G Ntrk1 neurotrophic receptor tyrosine kinase 1 JBrowse link 2 187,143,568 187,160,373 RGD:8554872
G Prlr prolactin receptor JBrowse link 2 60,131,410 60,325,686 RGD:13592920
G Ret ret proto-oncogene JBrowse link 4 150,202,170 150,249,196 RGD:7240710
RGD:8554872
RGD:11554173
lung small cell carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcy1 adenylate cyclase 1 JBrowse link 14 87,311,970 87,429,880 RGD:11554173
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:8554872
G Ascl1 achaete-scute family bHLH transcription factor 1 JBrowse link 7 28,038,662 28,040,504 RGD:11554173
G Avp arginine vasopressin JBrowse link 3 123,117,482 123,119,460 RGD:11554173
G B2m beta-2 microglobulin JBrowse link 3 114,087,287 114,093,311 RGD:8554872
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:13673911
G Bclaf1 BCL2-associated transcription factor 1 JBrowse link 1 15,799,753 15,828,838 RGD:11554173
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:13673912
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:13673920
G Cdyl chromodomain Y-like JBrowse link 17 29,672,925 29,895,416 RGD:11554173
G Ckb creatine kinase B JBrowse link 6 136,142,956 136,145,838 RGD:11554173
G Cntnap2 contactin associated protein 2 JBrowse link 4 74,700,539 77,025,463 RGD:11554173
G Col22a1 collagen type XXII alpha 1 chain JBrowse link 7 113,014,896 113,251,165 RGD:11554173
G Col4a2 collagen type IV alpha 2 chain JBrowse link 16 83,386,388 83,522,169 RGD:11554173
G Crebbp CREB binding protein JBrowse link 10 11,590,994 11,721,039 RGD:11554173
G Csf3 colony stimulating factor 3 JBrowse link 10 86,616,785 86,619,160 RGD:11554173
G Dip2c disco-interacting protein 2 homolog C JBrowse link 17 63,426,688 63,810,183 RGD:11554173
G Dnmt3b DNA methyltransferase 3 beta JBrowse link 3 149,131,541 149,170,061 RGD:9589086
G E2f1 E2F transcription factor 1 JBrowse link 3 150,062,895 150,073,721 RGD:13464335
RGD:13464344
RGD:13464337
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:11554173
G Elavl2 ELAV like RNA binding protein 2 JBrowse link 5 109,499,410 109,651,829 RGD:11554173
G Ep300 E1A binding protein p300 JBrowse link 7 122,818,194 122,889,055 RGD:11554173
G Epha7 Eph receptor A7 JBrowse link 5 43,602,744 43,761,198 RGD:11554173
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:11554173
G Grik3 glutamate ionotropic receptor kainate type subunit 3 JBrowse link 5 143,500,441 143,715,546 RGD:11554173
G Grm8 glutamate metabotropic receptor 8 JBrowse link 4 54,474,344 55,409,526 RGD:11554173
G Id2 inhibitor of DNA binding 2 JBrowse link 6 44,360,077 44,361,908 RGD:11554173
G Insm1 INSM transcriptional repressor 1 JBrowse link 3 140,427,961 140,430,467 RGD:11554173
G Itgb1 integrin subunit beta 1 JBrowse link 19 61,677,512 61,725,537 RGD:13792831
RGD:13792832
G Khsrp KH-type splicing regulatory protein JBrowse link 9 10,013,795 10,023,670 RGD:11554173
G Kif21a kinesin family member 21A JBrowse link 7 132,069,962 132,200,947 RGD:11554173
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 14 35,072,131 35,149,638 RGD:11554173
G Kmt2a lysine methyltransferase 2A JBrowse link 8 49,110,407 49,185,872 RGD:11554173
G Lama3 laminin subunit alpha 3 JBrowse link 18 3,704,866 3,941,215 RGD:13793369
G Lamb3 laminin subunit beta 3 JBrowse link 13 112,031,614 112,073,187 RGD:13793369
G Lamc2 laminin subunit gamma 2 JBrowse link 13 70,566,643 70,632,126 RGD:13793369
G Lyrm9 LYR motif containing 9 JBrowse link 10 66,099,478 66,113,559 RGD:11554173
G Max MYC associated factor X JBrowse link 6 99,984,260 100,011,460 RGD:13793386
G Mthfr methylenetetrahydrofolate reductase JBrowse link 5 164,844,642 164,864,360 RGD:4891158
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:13825123
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:13793389
G Mycl MYCL proto-oncogene, bHLH transcription factor JBrowse link 5 140,691,947 140,698,837 RGD:11554173
G Ndrg1 N-myc downstream regulated 1 JBrowse link 7 107,734,326 107,775,701 RGD:11554173
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha JBrowse link 2 118,831,350 118,861,456 RGD:8554872
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 2 31,742,326 31,826,882 RGD:13825123
G Plscr4 phospholipid scramblase 4 JBrowse link 8 99,880,073 99,917,733 RGD:11554173
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:11554173
RGD:8554872
G Ptk2 protein tyrosine kinase 2 JBrowse link 7 114,436,419 114,611,317 RGD:13825133
RGD:13825141
G Rarb retinoic acid receptor, beta JBrowse link 15 9,915,223 10,262,599 RGD:13825142
G Rassf8 Ras association domain family member 8 JBrowse link 4 180,059,020 180,135,924 RGD:11554173
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:11554173
RGD:8554872
G Rims2 regulating synaptic membrane exocytosis 2 JBrowse link 7 78,091,998 78,594,164 RGD:11554173
G Runx1t1 RUNX1 partner transcriptional co-repressor 1 JBrowse link 5 27,284,921 27,440,802 RGD:11554173
G Satb2 SATB homeobox 2 JBrowse link 9 63,456,877 63,642,193 RGD:11554173
G Skp2 S-phase kinase associated protein 2 JBrowse link 2 58,506,146 58,534,211 RGD:13825152
G Slit2 slit guidance ligand 2 JBrowse link 14 66,831,848 67,171,491 RGD:11554173
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 JBrowse link 8 22,648,323 22,739,468 RGD:11554173
G Sox2 SRY-box transcription factor 2 JBrowse link 2 121,165,137 121,167,545 RGD:11554173
G Tmem132d transmembrane protein 132D JBrowse link 12 31,934,343 32,607,768 RGD:11554173
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:11554173
RGD:8554872
G Xpo5 exportin 5 JBrowse link 9 17,125,201 17,163,170 RGD:11041738
G Zdbf2 zinc finger, DBF-type containing 2 JBrowse link 9 70,052,088 70,090,847 RGD:11554173
Medullary Carcinomas term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hpgd 15-hydroxyprostaglandin dehydrogenase JBrowse link 16 37,457,134 37,495,758 RGD:11554173
G Ret ret proto-oncogene JBrowse link 4 150,202,170 150,249,196 RGD:11554173
Merkel cell carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:11554173
G Sdhd succinate dehydrogenase complex subunit D JBrowse link 8 55,028,125 55,037,604 RGD:8554872
thyroid gland medullary carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kras KRAS proto-oncogene, GTPase JBrowse link 4 179,482,562 179,515,483 RGD:8554872
G Ret ret proto-oncogene JBrowse link 4 150,202,170 150,249,196 RGD:11554173
RGD:8554872
vipoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Men1 menin 1 JBrowse link 1 221,704,394 221,710,343 RGD:11554173
G Sst somatostatin JBrowse link 11 80,358,172 80,359,449 RGD:11554173

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15609
    disease of cellular proliferation 5822
      cancer 4157
        cell type cancer 3054
          carcinoma 1913
            neuroendocrine carcinoma 72
              Medullary Carcinomas + 6
              Merkel cell carcinoma 2
              Neuroendocrine Carcinoma of Salivary Glands, Sensorineural Hearing Loss, and Enamel Hypoplasia 0
              breast large cell neuroendocrine carcinoma 0
              lung small cell carcinoma + 62
              somatostatinoma 0
              vipoma + 2
Path 2
Term Annotations click to browse term
  disease 15609
    disease of cellular proliferation 5822
      Neoplasms by Site 5207
        organ system cancer 3976
          nervous system cancer 1738
            neuroectodermal tumor 785
              neuroendocrine tumor 622
                neuroendocrine carcinoma 72
                  Medullary Carcinomas + 6
                  Merkel cell carcinoma 2
                  Neuroendocrine Carcinoma of Salivary Glands, Sensorineural Hearing Loss, and Enamel Hypoplasia 0
                  breast large cell neuroendocrine carcinoma 0
                  lung small cell carcinoma + 62
                  somatostatinoma 0
                  vipoma + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.