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ONTOLOGY REPORT - ANNOTATIONS


Term:atherosclerosis
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Accession:DOID:1936 term browser browse the term
Definition:A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
Synonyms:exact_synonym: ALP;   ATHEROGENIC LIPOPROTEIN PHENOTYPE;   ATHEROSCLEROSIS SUSCEPTIBILITY;   ATHS;   Atherogenesis;   Atheroscleroses;   Atherosclerosis, Susceptibility To
 primary_id: MESH:D050197;   RDO:0007568
 alt_id: OMIM:108725
 xref: ICD10CM:I25.1;   ICD10CM:I70;   ICD9CM:440;   NCI:C35768;   NCI:C35771
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants       view all columns           Sort by:
 
atherosclerosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCA1 ATP binding cassette subfamily A member 1 JBrowse link 9 104,076,516 104,224,188 RGD:9068941
G ABCG5 ATP binding cassette subfamily G member 5 JBrowse link 2A 44,745,183 44,771,012 RGD:9068941
G ADD1 adducin 1 JBrowse link 4 2,889,073 2,975,012 RGD:9068941
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 3 192,341,471 192,354,885 RGD:9068941
G AGER advanced glycosylation end-product specific receptor JBrowse link 6 32,708,251 32,711,641 RGD:9068941
G AGT angiotensinogen JBrowse link 1 211,279,015 211,291,044 RGD:9068941
G AHR aryl hydrocarbon receptor JBrowse link 7 17,278,637 17,326,171 RGD:9068941
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 105,211,645 105,236,756 RGD:9068941
G ALOX15 arachidonate 15-lipoxygenase JBrowse link 17 4,677,125 4,687,669 RGD:9068941
G ALOX5 arachidonate 5-lipoxygenase JBrowse link 10 45,639,946 45,710,016 RGD:9068941
G ALOX5AP arachidonate 5-lipoxygenase activating protein JBrowse link 13 30,425,510 30,476,607 RGD:9068941
G APOA1 apolipoprotein A1 JBrowse link 11 115,606,136 115,608,335 RGD:9068941
G APOA4 apolipoprotein A4 JBrowse link 11 115,591,788 115,594,382 RGD:9068941
G APOE apolipoprotein E JBrowse link 19 50,459,906 50,463,490 RGD:9068941
G BCL3 BCL3 transcription coactivator JBrowse link 19 50,300,536 50,313,005 RGD:9068941
G CASP3 caspase 3 JBrowse link 4 189,018,422 189,040,217 RGD:9068941
G CASR calcium sensing receptor JBrowse link 3 126,252,765 126,285,268 RGD:9068941
G CAV1 caveolin 1 JBrowse link 7 121,193,678 121,229,655 RGD:9068941
G CCL2 C-C motif chemokine ligand 2 JBrowse link 17 22,821,336 22,823,271 RGD:9068941
G CCR5 C-C motif chemokine receptor 5 JBrowse link 3 47,377,564 47,383,625 RGD:9068941
G CCR6 C-C motif chemokine receptor 6 JBrowse link 6 170,069,689 170,084,779 RGD:9068941
G CD36 CD36 molecule JBrowse link 7 86,228,856 86,305,865 RGD:9068941
G CD40 CD40 molecule JBrowse link 20 43,541,619 43,552,994 RGD:9068941
G CD40LG CD40 ligand JBrowse link X 136,042,849 136,055,158 RGD:9068941
G CETP cholesteryl ester transfer protein JBrowse link 16 56,374,351 56,396,282 RGD:9068941
G CLU clusterin JBrowse link 8 24,070,053 24,086,934 RGD:9068941
G CNR2 cannabinoid receptor 2 JBrowse link 1 24,046,009 24,135,236 RGD:9068941
G COL4A2 collagen type IV alpha 2 chain JBrowse link 13 110,562,681 110,768,362 RGD:9068941
G CRP C-reactive protein JBrowse link 1 138,858,353 138,860,652 RGD:9068941
G CSF1 colony stimulating factor 1 JBrowse link 1 127,764,916 127,864,188 RGD:9068941
G CTSB cathepsin B RGD:9068941
G CTSD cathepsin D JBrowse link 11 1,821,442 1,832,970 RGD:9068941
G CTSL cathepsin L JBrowse link 9 86,903,001 86,908,303 RGD:9068941
G CTSS cathepsin S JBrowse link 1 129,733,996 129,768,318 RGD:9068941
G CX3CR1 C-X3-C motif chemokine receptor 1 JBrowse link 3 39,439,009 39,456,797 RGD:9068941
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 JBrowse link 2B 224,637,238 224,671,474 RGD:9068941
G EDN1 endothelin 1 JBrowse link 6 12,405,538 12,503,545 RGD:9068941
G EGLN1 egl-9 family hypoxia inducible factor 1 JBrowse link 1 211,939,543 211,997,325 RGD:9068941
G EPHX2 epoxide hydrolase 2 JBrowse link 8 23,964,094 24,017,749 RGD:9068941
G ESR1 estrogen receptor 1 JBrowse link 6 154,200,521 154,635,806 RGD:9068941
G ESR2 estrogen receptor 2 JBrowse link 14 63,064,397 63,175,303 RGD:9068941
G F11R F11 receptor JBrowse link 1 140,322,264 140,347,158 RGD:9068941
G F2 coagulation factor II, thrombin JBrowse link 11 47,227,891 47,249,157 RGD:9068941
G FAS Fas cell surface death receptor JBrowse link 10 89,199,070 89,244,884 RGD:9068941
G FASLG Fas ligand JBrowse link 1 151,868,430 151,876,281 RGD:9068941
G FCGR2A Fc fragment of IgG receptor IIa RGD:9068941
G FGF21 fibroblast growth factor 21 JBrowse link 19 54,345,966 54,347,712 RGD:9068941
G GRN granulin precursor JBrowse link 17 13,211,784 13,219,793 RGD:9068941
G GSTM1 glutathione S-transferase mu 1 JBrowse link 1 128,003,736 128,009,696 RGD:9068941
G HMGB1 high mobility group box 1 JBrowse link 13 30,173,875 30,179,527 RGD:9068941
G HNRNPC heterogeneous nuclear ribonucleoprotein C JBrowse link 14 20,103,594 20,163,824 RGD:9068941
G HRH1 histamine receptor H1 JBrowse link 3 11,439,705 11,545,509 RGD:9068941
G ICAM1 intercellular adhesion molecule 1 JBrowse link 19 10,484,414 10,500,605 RGD:9068941
G IFNG interferon gamma JBrowse link 12 68,448,861 68,453,829 RGD:9068941
G IGF2 insulin like growth factor 2 JBrowse link 11 2,202,764 2,228,890 RGD:9068941
G IL17A interleukin 17A JBrowse link 6 53,004,820 53,009,074 RGD:9068941
G IL18 interleukin 18 JBrowse link 11 110,867,586 110,888,371 RGD:9068941
G IL1B interleukin 1 beta JBrowse link 2A 113,846,299 113,853,424 RGD:9068941
G IL2 interleukin 2 JBrowse link 4 125,782,563 125,787,819 RGD:9068941
G IL6 interleukin 6 JBrowse link 7 23,027,560 23,032,419 RGD:9068941
G KDR kinase insert domain receptor JBrowse link 4 75,377,847 75,424,927 RGD:9068941
G KL klotho JBrowse link 13 32,697,381 32,752,578 RGD:9068941
G LDLR low density lipoprotein receptor JBrowse link 19 11,357,311 11,402,736 RGD:9068941
G LOC100984838 low affinity immunoglobulin gamma Fc region receptor II-b JBrowse link 1 140,882,104 140,890,036 RGD:9068941
G LOC100986914 cytochrome b-245 light chain JBrowse link 16 89,016,349 89,024,719 RGD:9068941
G LTA4H leukotriene A4 hydrolase JBrowse link 12 96,978,203 97,012,427 RGD:9068941
G MMP1 matrix metallopeptidase 1 JBrowse link 11 101,221,393 101,230,104 RGD:9068941
G MMP2 matrix metallopeptidase 2 JBrowse link 16 54,817,228 54,844,279 RGD:9068941
G MTHFR methylenetetrahydrofolate reductase JBrowse link 1 11,766,334 11,785,645 RGD:9068941
G NECTIN2 nectin cell adhesion molecule 2 JBrowse link 19 50,399,367 50,443,024 RGD:9068941
G NGF nerve growth factor JBrowse link 1 122,272,750 122,325,909 RGD:9068941
G NGFR nerve growth factor receptor JBrowse link 17 8,075,301 8,094,966 RGD:9068941
G NOD2 nucleotide binding oligomerization domain containing 2 JBrowse link 16 49,834,385 49,873,783 RGD:9068941
G NOS2 nitric oxide synthase 2 JBrowse link 17 29,477,285 29,519,412 RGD:9068941
G NOS3 nitric oxide synthase 3 JBrowse link 7 154,730,009 154,755,233 RGD:9068941
G NPC1 NPC intracellular cholesterol transporter 1 JBrowse link 18 20,409,040 20,463,623 RGD:9068941
G NPPB natriuretic peptide B JBrowse link 1 11,838,518 11,839,999 RGD:9068941
G NPY neuropeptide Y JBrowse link 7 24,566,963 24,574,657 RGD:9068941
G NPY1R neuropeptide Y receptor Y1 JBrowse link 4 167,372,306 167,392,716 RGD:9068941
G NPY2R neuropeptide Y receptor Y2 JBrowse link 4 159,360,854 159,404,224 RGD:9068941
G NPY5R neuropeptide Y receptor Y5 JBrowse link 4 167,392,174 167,400,258 RGD:9068941
G NR1H4 nuclear receptor subfamily 1 group H member 4 JBrowse link 12 101,457,885 101,548,058 RGD:9068941
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 1 206,812,981 206,860,356 RGD:9068941
G PDGFRB platelet derived growth factor receptor beta JBrowse link 5 151,543,581 151,585,630 RGD:9068941
G PECAM1 platelet and endothelial cell adhesion molecule 1 JBrowse link 17 63,511,784 63,601,241 RGD:9068941
G PGF placental growth factor JBrowse link 14 74,338,976 74,352,964 RGD:9068941
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma JBrowse link 7 111,569,947 111,611,614 RGD:9068941
G PLA2G2A phospholipase A2 group IIA JBrowse link 1 19,973,352 19,977,627 RGD:9068941
G PLA2G7 phospholipase A2 group VII JBrowse link 6 47,558,861 47,590,212 RGD:9068941
G PLAT plasminogen activator, tissue type JBrowse link 8 38,864,918 38,897,776 RGD:9068941
G PLAU plasminogen activator, urokinase JBrowse link 10 73,104,808 73,113,136 RGD:9068941
G PLTP phospholipid transfer protein JBrowse link 20 43,324,608 43,337,999 RGD:9068941
G PON1 paraoxonase 1 JBrowse link 7 100,841,286 100,867,493 RGD:9068941
G PON3 paraoxonase 3 JBrowse link 7 100,902,432 100,941,611 RGD:9068941
G PPARG peroxisome proliferator activated receptor gamma JBrowse link 3 12,560,670 12,705,060 RGD:9068941
G PTGES3 prostaglandin E synthase 3 JBrowse link 12 32,475,989 32,503,181 RGD:9068941
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 166,355,845 166,364,517 RGD:9068941
G SELL selectin L JBrowse link 1 148,895,373 148,916,393 RGD:9068941
G SELP selectin P JBrowse link 1 148,793,677 148,834,701 RGD:9068941
G SERPINE1 serpin family E member 1 JBrowse link 7 106,511,539 106,518,605 RGD:9068941
G SIRT1 sirtuin 1 JBrowse link 10 66,681,983 66,714,065 RGD:9068941
G SOCS3 suppressor of cytokine signaling 3 JBrowse link 17 77,981,752 77,985,059 RGD:9068941
G SOD1 superoxide dismutase 1 JBrowse link 21 31,411,702 31,419,432 RGD:9068941
G SOD2 superoxide dismutase 2 JBrowse link 6 162,576,082 162,589,960 RGD:9068941
G STAT3 signal transducer and activator of transcription 3 JBrowse link 17 15,152,358 15,227,084 RGD:9068941
G TLR2 toll like receptor 2 JBrowse link 4 157,848,058 157,870,324 RGD:9068941
G TLR4 toll like receptor 4 JBrowse link 9 117,180,250 117,193,510 RGD:9068941
G TNF tumor necrosis factor JBrowse link 6 32,126,618 32,129,389 RGD:9068941
G TRIM28 tripartite motif containing 28 JBrowse link 19 64,369,979 64,377,144 RGD:9068941
G TRPV1 transient receptor potential cation channel subfamily V member 1 JBrowse link 17 3,609,952 3,655,011 RGD:9068941
G TTPA alpha tocopherol transfer protein JBrowse link 8 61,266,954 61,293,165 RGD:9068941
G UCN2 urocortin 2 JBrowse link 3 49,566,535 49,566,873 RGD:9068941
G VCAM1 vascular cell adhesion molecule 1 JBrowse link 1 102,091,121 102,108,494 RGD:9068941
G VDR vitamin D receptor JBrowse link 12 41,661,688 41,766,192 RGD:9068941
G VEGFA vascular endothelial growth factor A JBrowse link 6 44,651,855 44,666,353 RGD:9068941
G VEGFC vascular endothelial growth factor C JBrowse link 4 181,104,737 181,236,024 RGD:9068941
G VIM vimentin JBrowse link 10 17,818,285 17,826,642 RGD:9068941
aortic atherosclerosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APOE apolipoprotein E JBrowse link 19 50,459,906 50,463,490 RGD:9068941
G CAPN1 calpain 1 JBrowse link 11 63,884,451 63,916,731 RGD:9068941
Carotid Atherosclerosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FGF21 fibroblast growth factor 21 JBrowse link 19 54,345,966 54,347,712 RGD:9068941
G PCSK5 proprotein convertase subtilisin/kexin type 5 JBrowse link 9 74,745,187 75,224,347 RGD:9068941
G SIRT1 sirtuin 1 JBrowse link 10 66,681,983 66,714,065 RGD:9068941
Carotid Intimal Medial Thickness 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PPARG peroxisome proliferator activated receptor gamma JBrowse link 3 12,560,670 12,705,060 RGD:7240710
RGD:9068941
Peripheral Arterial Occlusive Disease 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SERPINA3 serpin family A member 3 JBrowse link 14 94,551,934 94,579,515 RGD:9068941
peripheral artery disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 3 192,341,471 192,354,885 RGD:9068941
G B2M beta-2-microglobulin JBrowse link 15 41,836,321 41,842,991 RGD:9068941
G BMP2 bone morphogenetic protein 2 JBrowse link 20 6,546,173 6,558,627 RGD:9068941
G BMP8A bone morphogenetic protein 8a JBrowse link 1 40,122,134 40,138,165 RGD:9068941
G MTHFR methylenetetrahydrofolate reductase JBrowse link 1 11,766,334 11,785,645 RGD:9068941
G NPY neuropeptide Y JBrowse link 7 24,566,963 24,574,657 RGD:9068941
G NPY1R neuropeptide Y receptor Y1 JBrowse link 4 167,372,306 167,392,716 RGD:9068941
G NPY2R neuropeptide Y receptor Y2 JBrowse link 4 159,360,854 159,404,224 RGD:9068941
G NPY5R neuropeptide Y receptor Y5 JBrowse link 4 167,392,174 167,400,258 RGD:9068941
G P2RY12 purinergic receptor P2Y12 JBrowse link 3 155,934,333 155,981,818 RGD:9068941
G SERPINE1 serpin family E member 1 JBrowse link 7 106,511,539 106,518,605 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 12321
    disease of anatomical entity 12002
      cardiovascular system disease 3199
        vascular disease 2270
          artery disease 1504
            arteriosclerosis 546
              atherosclerosis 124
                Carotid Atherosclerosis 3
                Carotid Intimal Medial Thickness 1 1
                Premature Atherosclerosis with Deafness, Nephropathy, Diabetes Mellitus, Photomyoclonus, and Degenerative Neurologic Disease 0
                aortic atherosclerosis 2
                cerebral atherosclerosis 0
                generalized atherosclerosis 0
                peripheral artery disease + 12
                renal artery atheroma 0
Path 2
Term Annotations click to browse term
  disease 12321
    disease of anatomical entity 12002
      cardiovascular system disease 3199
        vascular disease 2270
          artery disease 1504
            arteriosclerosis 546
              arteriosclerotic cardiovascular disease 124
                atherosclerosis 124
                  Carotid Atherosclerosis 3
                  Carotid Intimal Medial Thickness 1 1
                  Premature Atherosclerosis with Deafness, Nephropathy, Diabetes Mellitus, Photomyoclonus, and Degenerative Neurologic Disease 0
                  aortic atherosclerosis 2
                  cerebral atherosclerosis 0
                  generalized atherosclerosis 0
                  peripheral artery disease + 12
                  renal artery atheroma 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.