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ONTOLOGY REPORT - ANNOTATIONS


Term:atherosclerosis
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Accession:DOID:1936 term browser browse the term
Definition:A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
Synonyms:exact_synonym: ALP;   ATHEROGENIC LIPOPROTEIN PHENOTYPE;   ATHEROSCLEROSIS SUSCEPTIBILITY;   ATHS;   Atherogenesis;   Atheroscleroses;   Atherosclerosis, Susceptibility To
 primary_id: MESH:D050197;   RDO:0007568
 alt_id: OMIM:108725
 xref: ICD10CM:I25.1;   ICD10CM:I70;   ICD9CM:440;   NCI:C35768;   NCI:C35771
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants       view all columns           Sort by:
 
atherosclerosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCA1 ATP binding cassette subfamily A member 1 JBrowse link 11 60,761,669 60,869,753 RGD:9068941
G ABCG5 ATP binding cassette subfamily G member 5 JBrowse link 10 46,261,747 46,300,084 RGD:9068941
G ADD1 adducin 1 JBrowse link 3 61,356,643 61,443,851 RGD:9068941
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 34 19,398,310 19,410,519 RGD:9068941
G AGER advanced glycosylation end-product specific receptor JBrowse link 12 1,574,251 1,577,410 RGD:9068941
G AGT angiotensinogen JBrowse link 4 8,681,192 8,694,059 RGD:9068941
G AHR aryl hydrocarbon receptor JBrowse link 14 31,743,704 31,793,484 RGD:9068941
G AKT1 AKT serine/threonine kinase 1 JBrowse link 8 72,317,399 72,335,686 RGD:9068941
G ALOX15 arachidonate 15-lipoxygenase JBrowse link 5 31,883,544 31,891,357 RGD:9068941
G ALOX5 arachidonate 5-lipoxygenase JBrowse link 28 2,170,920 2,218,765 RGD:9068941
G ALOX5AP arachidonate 5-lipoxygenase activating protein JBrowse link 25 9,320,868 9,351,056 RGD:9068941
G APOA1 apolipoprotein A1 JBrowse link 5 16,740,071 16,742,081 RGD:9068941
G APOA4 apolipoprotein A4 JBrowse link 5 16,751,588 16,754,215 RGD:9068941
G APOE apolipoprotein E JBrowse link 1 110,525,717 110,528,534 RGD:9068941
G BCL3 BCL3 transcription coactivator JBrowse link 1 110,620,850 110,628,830 RGD:9068941
G CASP3 caspase 3 JBrowse link 16 45,920,074 45,940,507 RGD:9068941
G CASR calcium sensing receptor JBrowse link 33 25,340,822 25,432,814 RGD:9068941
G CAV1 caveolin 1 JBrowse link 14 55,458,934 55,494,563 RGD:9068941
G CCL2 C-C motif chemokine ligand 2 JBrowse link 9 39,008,187 39,009,932 RGD:9068941
G CCL4 chemokine (C-C motif) ligand 4 JBrowse link 9 37,681,342 37,682,691 RGD:9068941
G CCR5 C-C motif chemokine receptor 5 JBrowse link 20 42,293,288 42,297,952 RGD:9068941
G CCR6 C-C motif chemokine receptor 6 JBrowse link 1 54,932,798 54,960,646 RGD:9068941
G CD36 CD36 molecule JBrowse link 18 20,299,808 20,375,856 RGD:9068941
G CD40 CD40 molecule JBrowse link 24 33,352,992 33,383,488 RGD:9068941
G CD40LG CD40 ligand JBrowse link X 107,001,421 107,023,007 RGD:9068941
G CLU clusterin JBrowse link 25 29,982,811 29,999,565 RGD:9068941
G CNR2 cannabinoid receptor 2 JBrowse link 2 75,640,636 75,662,000 RGD:9068941
G COL4A2 collagen type IV alpha 2 chain JBrowse link 22 58,656,579 58,820,560 RGD:9068941
G CRP C-reactive protein JBrowse link 38 22,396,787 22,398,180 RGD:9068941
G CSF1 colony stimulating factor 1 JBrowse link 6 42,028,454 42,047,028 RGD:9068941
G CTSB cathepsin B JBrowse link 25 26,048,237 26,056,570 RGD:9068941
G CTSD cathepsin D JBrowse link 18 46,010,440 46,019,457 RGD:9068941
G CTSS cathepsin S JBrowse link 17 59,893,840 59,910,878 RGD:9068941
G CX3CR1 C-X3-C motif chemokine receptor 1 JBrowse link 23 8,937,069 8,954,738 RGD:9068941
G CYBA cytochrome b-245 alpha chain JBrowse link 5 64,692,865 64,701,056 RGD:9068941
G CYP27A1 cytochrome P450 family 27 subfamily A member 1 JBrowse link 37 25,366,475 25,401,978 RGD:9068941
G EDN1 endothelin 1 JBrowse link 35 11,808,892 11,815,383 RGD:9068941
G EGLN1 egl-9 family hypoxia inducible factor 1 JBrowse link 4 8,053,486 8,110,791 RGD:9068941
G EPHX2 epoxide hydrolase 2 JBrowse link 25 30,045,040 30,107,110 RGD:9068941
G ESR1 estrogen receptor 1 JBrowse link 1 42,081,952 42,368,544 RGD:9068941
G ESR2 estrogen receptor 2 JBrowse link 8 38,645,917 38,715,347 RGD:9068941
G F11R F11 receptor JBrowse link 38 21,433,819 21,456,722 RGD:9068941
G F2 coagulation factor II, thrombin JBrowse link 18 42,782,744 42,799,531 RGD:9068941
G FAS Fas cell surface death receptor JBrowse link 26 38,738,811 38,763,298 RGD:9068941
G FASLG Fas ligand JBrowse link 7 26,335,837 26,344,224 RGD:9068941
G FGF21 fibroblast growth factor 21 JBrowse link 1 107,571,449 107,576,630 RGD:9068941
G GRN granulin precursor JBrowse link 9 19,077,430 19,085,443 RGD:9068941
G HMGB1 high mobility group box 1 JBrowse link 25 9,431,223 9,558,167 RGD:9068941
G HNRNPC heterogeneous nuclear ribonucleoprotein C JBrowse link 15 18,239,810 18,299,065 RGD:9068941
G HRH1 histamine receptor H1 JBrowse link 20 7,160,903 7,236,147 RGD:9068941
G HSP70 heat shock protein 70 JBrowse link 12 1,285,282 1,287,670 RGD:9068941
G ICAM1 intercellular adhesion molecule 1 JBrowse link 20 50,818,715 50,827,914 RGD:9068941
G IFNG interferon gamma JBrowse link 10 10,406,866 10,411,698 RGD:9068941
G IGF2 insulin like growth factor 2 JBrowse link 18 46,294,036 46,311,982 RGD:9068941
G IL17A interleukin 17A JBrowse link 12 19,854,129 19,862,521 RGD:9068941
G IL18 interleukin 18 JBrowse link 5 20,972,742 20,995,327 RGD:9068941
G IL1B interleukin 1 beta JBrowse link 17 37,019,329 37,033,388 RGD:9068941
G IL2 interleukin 2 JBrowse link 19 17,750,780 17,756,394 RGD:9068941
G IL6 interleukin 6 JBrowse link 14 36,474,268 36,478,519 RGD:9068941
G KDR kinase insert domain receptor JBrowse link 13 47,442,861 47,484,574 RGD:9068941
G KL klotho JBrowse link 25 7,154,359 7,201,744 RGD:9068941
G LDLR low density lipoprotein receptor JBrowse link 20 50,115,175 50,152,443 RGD:9068941
G LOC100856270 low affinity immunoglobulin gamma Fc region receptor II JBrowse link 38 20,980,777 20,994,403 RGD:9068941
G LOC479668 haptoglobin-like JBrowse link 5 77,795,183 77,800,034 RGD:9068941
G LTA4H leukotriene A4 hydrolase JBrowse link 15 35,795,934 35,830,681 RGD:9068941
G MIR155 microRNA mir-155 JBrowse link 31 21,078,768 21,078,828 RGD:9068941
G MIR21 microRNA mir-21 JBrowse link 9 34,340,550 34,340,609 RGD:9068941
G MIR223 microRNA mir-223 JBrowse link X 50,838,131 50,838,233 RGD:9068941
G MMP1 matrix metallopeptidase 1 JBrowse link 5 28,978,385 28,986,644 RGD:9068941
G MMP2 matrix metallopeptidase 2 JBrowse link 2 60,471,092 60,492,991 RGD:9068941
G MTHFR methylenetetrahydrofolate reductase JBrowse link 2 84,445,526 84,457,435 RGD:9068941
G NECTIN2 nectin cell adhesion molecule 2 JBrowse link 1 110,543,140 110,569,168 RGD:9068941
G NGF nerve growth factor JBrowse link 17 52,900,647 52,901,607 RGD:9068941
G NGFR nerve growth factor receptor JBrowse link 9 25,598,468 25,621,021 RGD:9068941
G NOD2 nucleotide binding oligomerization domain containing 2 JBrowse link 2 64,636,850 64,667,232 RGD:9068941
G NOS2 nitric oxide synthase 2 JBrowse link 9 42,171,821 42,210,217 RGD:9068941
G NOS3 nitric oxide synthase 3 JBrowse link 16 15,054,196 15,072,454 RGD:9068941
G NPC1 NPC intracellular cholesterol transporter 1 JBrowse link 7 64,764,941 64,802,507 RGD:9068941
G NPPB natriuretic peptide B JBrowse link 2 84,395,844 84,397,473 RGD:9068941
G NPY neuropeptide Y JBrowse link 14 37,824,579 37,831,289 RGD:9068941
G NPY1R neuropeptide Y receptor Y1 JBrowse link 15 59,580,546 59,587,753 RGD:9068941
G NPY2R neuropeptide Y receptor Y2 JBrowse link 15 52,790,136 52,797,785 RGD:9068941
G NPY5R neuropeptide Y receptor Y5 JBrowse link 15 59,600,212 59,608,576 RGD:9068941
G NR1H4 nuclear receptor subfamily 1 group H member 4 JBrowse link 15 39,497,313 39,608,120 RGD:9068941
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 7 38,503,072 38,542,556 RGD:9068941
G PDGFRB platelet derived growth factor receptor beta JBrowse link 4 58,925,922 58,963,639 RGD:9068941
G PECAM1 platelet and endothelial cell adhesion molecule 1 JBrowse link 9 12,166,124 12,219,553 RGD:9068941
G PGF placental growth factor JBrowse link 8 48,059,554 48,110,534 RGD:9068941
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma JBrowse link 18 13,576,966 13,611,748 RGD:9068941
G PLA2G7 phospholipase A2 group VII JBrowse link 12 14,866,229 14,908,230 RGD:9068941
G PLAT plasminogen activator, tissue type JBrowse link 16 23,469,590 23,496,013 RGD:9068941
G PLAU plasminogen activator, urokinase JBrowse link 4 24,329,139 24,333,893 RGD:9068941
G PLTP phospholipid transfer protein JBrowse link 24 33,189,098 33,199,935 RGD:9068941
G PON1 paraoxonase 1 JBrowse link 14 20,565,620 20,600,774 RGD:9068941
G PON3 paraoxonase 3 JBrowse link 14 20,615,180 20,642,807 RGD:9068941
G PPARG peroxisome proliferator activated receptor gamma JBrowse link 20 6,134,618 6,265,481 RGD:9068941
G PTGES3 prostaglandin E synthase 3 JBrowse link 10 885,744 903,814 RGD:9068941
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 7 19,668,079 19,674,903 RGD:9068941
G SELL selectin L JBrowse link 7 28,906,752 28,927,959 RGD:9068941
G SELP selectin P JBrowse link 7 28,956,428 28,997,266 RGD:9068941
G SERPINE1 serpin family E member 1 JBrowse link 6 8,719,547 8,727,160 RGD:9068941
G SIRT1 sirtuin 1 JBrowse link 4 19,188,616 19,220,031 RGD:9068941
G SOCS3 suppressor of cytokine signaling 3 JBrowse link 9 2,859,267 2,859,944 RGD:9068941
G SOD1 superoxide dismutase 1 JBrowse link 31 26,540,291 26,544,212 RGD:9068941
G SOD2 superoxide dismutase 2 JBrowse link 1 48,943,472 48,955,158 RGD:9068941
G STAT3 signal transducer and activator of transcription 3 JBrowse link 9 20,539,660 20,614,631 RGD:9068941
G TLR2 toll like receptor 2 JBrowse link 15 51,454,557 51,465,429 RGD:9068941
G TLR4 toll like receptor 4 JBrowse link 11 71,356,390 71,367,166 RGD:9068941
G TNF tumor necrosis factor JBrowse link 12 1,074,561 1,076,425 RGD:9068941
G TRIM28 tripartite motif containing 28 JBrowse link 1 99,408,920 99,415,432 RGD:9068941
G TRPV1 transient receptor potential cation channel subfamily V member 1 JBrowse link 9 47,404,987 47,443,871 RGD:9068941
G TTPA alpha tocopherol transfer protein JBrowse link 29 13,177,690 13,198,910 RGD:9068941
G UCN2 urocortin 2 JBrowse link 20 40,551,060 40,552,920 RGD:9068941
G VCAM1 vascular cell adhesion molecule 1 JBrowse link 6 49,341,669 49,359,841 RGD:9068941
G VDR vitamin D receptor JBrowse link 27 6,852,915 6,909,466 RGD:9068941
G VEGFA vascular endothelial growth factor A JBrowse link 12 12,209,032 12,224,978 RGD:9068941
G VEGFC vascular endothelial growth factor C JBrowse link 16 52,883,242 52,987,684 RGD:9068941
G VIM vimentin JBrowse link 2 19,671,316 19,679,367 RGD:9068941
aortic atherosclerosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APOE apolipoprotein E JBrowse link 1 110,525,717 110,528,534 RGD:9068941
G CAPN1 calpain 1 JBrowse link 18 51,983,266 52,010,831 RGD:9068941
G MIR223 microRNA mir-223 JBrowse link X 50,838,131 50,838,233 RGD:9068941
Carotid Atherosclerosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FGF21 fibroblast growth factor 21 JBrowse link 1 107,571,449 107,576,630 RGD:9068941
G PCSK5 proprotein convertase subtilisin/kexin type 5 JBrowse link 1 82,088,090 82,506,131 RGD:9068941
G SIRT1 sirtuin 1 JBrowse link 4 19,188,616 19,220,031 RGD:9068941
Carotid Intimal Medial Thickness 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PPARG peroxisome proliferator activated receptor gamma JBrowse link 20 6,134,618 6,265,481 RGD:7240710
RGD:9068941
Peripheral Arterial Occlusive Disease 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC480425 alpha-1-antichymotrypsin JBrowse link 8 63,588,188 63,596,955 RGD:9068941
peripheral artery disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 34 19,398,310 19,410,519 RGD:9068941
G B2M beta-2-microglobulin JBrowse link 30 11,331,574 11,337,991 RGD:9068941
G BMP2 bone morphogenetic protein 2 JBrowse link 24 15,199,667 15,211,509 RGD:9068941
G MTHFR methylenetetrahydrofolate reductase JBrowse link 2 84,445,526 84,457,435 RGD:9068941
G NPY neuropeptide Y JBrowse link 14 37,824,579 37,831,289 RGD:9068941
G NPY1R neuropeptide Y receptor Y1 JBrowse link 15 59,580,546 59,587,753 RGD:9068941
G NPY2R neuropeptide Y receptor Y2 JBrowse link 15 52,790,136 52,797,785 RGD:9068941
G NPY5R neuropeptide Y receptor Y5 JBrowse link 15 59,600,212 59,608,576 RGD:9068941
G P2RY12 purinergic receptor P2Y12 JBrowse link 23 45,908,574 45,954,675 RGD:9068941
G SERPINE1 serpin family E member 1 JBrowse link 6 8,719,547 8,727,160 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 12489
    disease of anatomical entity 12172
      cardiovascular system disease 3293
        vascular disease 2357
          artery disease 1543
            arteriosclerosis 558
              atherosclerosis 124
                Carotid Atherosclerosis 3
                Carotid Intimal Medial Thickness 1 1
                Premature Atherosclerosis with Deafness, Nephropathy, Diabetes Mellitus, Photomyoclonus, and Degenerative Neurologic Disease 0
                aortic atherosclerosis 3
                cerebral atherosclerosis 0
                generalized atherosclerosis 0
                peripheral artery disease + 11
                renal artery atheroma 0
Path 2
Term Annotations click to browse term
  disease 12489
    disease of anatomical entity 12172
      cardiovascular system disease 3293
        vascular disease 2357
          artery disease 1543
            arteriosclerosis 558
              arteriosclerotic cardiovascular disease 124
                atherosclerosis 124
                  Carotid Atherosclerosis 3
                  Carotid Intimal Medial Thickness 1 1
                  Premature Atherosclerosis with Deafness, Nephropathy, Diabetes Mellitus, Photomyoclonus, and Degenerative Neurologic Disease 0
                  aortic atherosclerosis 3
                  cerebral atherosclerosis 0
                  generalized atherosclerosis 0
                  peripheral artery disease + 11
                  renal artery atheroma 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.