Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:atherosclerosis
go back to main search page
Accession:DOID:1936 term browser browse the term
Definition:A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
Synonyms:exact_synonym: ALP;   ATHEROGENIC LIPOPROTEIN PHENOTYPE;   ATHEROSCLEROSIS SUSCEPTIBILITY;   ATHS;   Atherogenesis;   Atheroscleroses;   Atherosclerosis, Susceptibility To
 primary_id: MESH:D050197;   RDO:0007568
 alt_id: OMIM:108725
 xref: ICD10CM:I25.1;   ICD10CM:I70;   ICD9CM:440;   NCI:C35768;   NCI:C35771
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants       view all columns           Sort by:
 
atherosclerosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCA1 ATP binding cassette subfamily A member 1 JBrowse link 1 246,144,277 246,278,492 RGD:9068941
G ABCG5 ATP binding cassette subfamily G member 5 JBrowse link 3 96,616,304 96,656,893 RGD:9068941
G ADD1 adducin 1 JBrowse link 8 1,627,146 1,710,653 RGD:9068941
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 13 124,633,906 124,646,237 RGD:9068941
G AGER advanced glycosylation end-product specific receptor JBrowse link 7 24,218,116 24,221,162 RGD:9068941
G AGT angiotensinogen JBrowse link 14 59,643,030 59,656,835 RGD:9068941
G AHR aryl hydrocarbon receptor JBrowse link 9 86,511,866 86,555,950 RGD:9068941
G AKT1 AKT serine/threonine kinase 1 RGD:9068941
G ALOX15 arachidonate 15-lipoxygenase JBrowse link 12 52,287,174 52,295,873 RGD:9068941
G ALOX5 arachidonate 5-lipoxygenase JBrowse link 14 90,859,209 90,907,084 RGD:9068941
G ALOX5AP arachidonate 5-lipoxygenase activating protein JBrowse link 11 7,371,328 7,438,111 RGD:9068941
G APOA1 apolipoprotein A1 JBrowse link 9 44,216,481 44,218,360 RGD:9068941
G APOA4 apolipoprotein A4 JBrowse link 9 44,201,587 44,204,072 RGD:9068941
G APOE apolipoprotein E JBrowse link 6 51,373,113 51,375,333 RGD:9068941
G BCL3 BCL3 transcription coactivator JBrowse link 6 51,256,033 51,264,923 RGD:9068941
G CASP3 caspase 3 JBrowse link 15 45,744,320 45,753,252 RGD:9068941
G CASR calcium sensing receptor JBrowse link 13 138,279,785 138,364,934 RGD:9068941
G CAV1 caveolin 1 JBrowse link 18 29,648,120 29,682,451 RGD:9068941
G CCL2 chemokine (C-C motif) ligand 2 JBrowse link 12 40,798,109 40,800,013 RGD:9068941
G CCL3L1 chemokine (C-C motif) ligand 3-like 1 JBrowse link 12 39,491,999 39,493,345 RGD:9068941
G CCL4 C-C motif chemokine ligand 4 JBrowse link 12 39,479,190 39,480,511 RGD:9068941
G CCR5 chemokine (C-C motif) receptor 5 JBrowse link 13 29,382,383 29,387,902 RGD:9068941
G CCR6 C-C motif chemokine receptor 6 JBrowse link 1 2,016,600 2,034,172 RGD:9068941
G CD36 CD36 molecule JBrowse link 9 99,685,748 99,782,296 RGD:9068941
G CD40 CD40 molecule JBrowse link 17 48,286,116 48,298,188 RGD:9068941
G CD40LG CD40 ligand JBrowse link X 111,778,666 111,788,901 RGD:9068941
G CELA2A chymotrypsin-like elastase family, member 2A JBrowse link 6 74,691,653 74,707,598 RGD:9068941
G CLU clusterin JBrowse link 14 11,336,585 11,352,569 RGD:9068941
G CNR2 cannabinoid receptor 2 JBrowse link 6 81,659,162 81,692,550 RGD:9068941
G COL4A2 collagen type IV alpha 2 chain JBrowse link 11 76,996,885 77,161,617 RGD:9068941
G CRP C-reactive protein, pentraxin-related JBrowse link 4 90,793,361 90,801,020 RGD:9068941
G CSF1 colony stimulating factor 1 JBrowse link 4 110,178,466 110,198,232 RGD:9068941
G CTSB cathepsin B JBrowse link 14 15,014,139 15,035,081 RGD:9068941
G CTSD cathepsin D JBrowse link 2 1,188,548 1,197,642 RGD:9068941
G CTSL cathepsin L JBrowse link 10 27,668,523 27,674,705 RGD:9068941
G CTSS cathepsin S JBrowse link 4 98,415,273 98,442,952 RGD:9068941
G CX3CR1 C-X3-C motif chemokine receptor 1 JBrowse link 13 23,944,386 23,957,567 RGD:9068941
G CYBA cytochrome b-245 alpha chain JBrowse link 6 1,015,212 1,021,422 RGD:9068941
G CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 JBrowse link 15 120,809,886 120,852,196 RGD:9068941
G EDN1 endothelin 1 JBrowse link 7 8,752,018 8,758,354 RGD:9068941
G EGLN1 egl-9 family hypoxia inducible factor 1 JBrowse link 14 59,113,527 59,168,421 RGD:9068941
G EPHX2 epoxide hydrolase 2 JBrowse link 14 11,217,125 11,293,018 RGD:9068941
G ESR1 estrogen receptor 1 JBrowse link 1 14,217,032 14,604,906 RGD:9068941
G ESR2 estrogen receptor 2 JBrowse link 1 193,823,666 193,907,330 RGD:9068941
G F11R F11 receptor JBrowse link 4 89,425,101 89,447,889 RGD:9068941
G F2 coagulation factor II, thrombin JBrowse link 2 15,793,257 15,819,151 RGD:9068941
G FAS Fas cell surface death receptor JBrowse link 14 100,927,305 100,954,781 RGD:9068941
G FASLG Fas ligand (TNF superfamily, member 6) JBrowse link 9 115,068,314 115,075,147 RGD:9068941
G FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) JBrowse link 4 88,873,762 88,892,964 RGD:9068941
G FGF21 fibroblast growth factor 21 JBrowse link 6 54,082,653 54,084,532 RGD:9068941
G GRN granulin precursor JBrowse link 12 18,893,772 18,900,444 RGD:9068941
G HMGB1 high mobility group box 1 JBrowse link 11 7,195,556 7,321,071 RGD:9068941
G HNRNPC heterogeneous nuclear ribonucleoprotein C JBrowse link 7 77,921,098 77,978,550 RGD:9068941
G HP haptoglobin JBrowse link 6 14,980,382 14,985,245 RGD:9068941
G HRH1 histamine receptor H1 JBrowse link 13 67,209,261 67,411,174 RGD:9068941
G ICAM1 intercellular adhesion molecule 1 JBrowse link 2 69,097,136 69,107,722 RGD:9068941
G IFNG interferon gamma JBrowse link 5 32,477,906 32,482,670 RGD:9068941
G IGF2 insulin like growth factor 2 JBrowse link 2 1,469,183 1,496,417 RGD:9068941
G IL17A interleukin 17A JBrowse link 7 46,013,584 46,017,161 RGD:9068941
G IL18 interleukin 18 JBrowse link 9 39,839,959 39,861,258 RGD:9068941
G IL2 interleukin 2 JBrowse link 8 101,640,938 101,645,683 RGD:9068941
G IL6 interleukin 6 JBrowse link 9 91,506,421 91,510,830 RGD:9068941
G KDR kinase insert domain receptor JBrowse link 8 41,809,116 41,856,379 RGD:9068941
G KL klotho JBrowse link 11 9,427,236 9,479,251 RGD:9068941
G LDLR low density lipoprotein receptor JBrowse link 2 69,828,348 69,864,823 RGD:9068941
G LOC110258578 interleukin-1 beta-like RGD:9068941
G LTA4H leukotriene A4 hydrolase JBrowse link 5 87,486,552 87,518,520 RGD:9068941
G MIR155 microRNA mir-155 JBrowse link 13 189,138,822 189,138,902 RGD:9068941
G MIR21 microRNA mir-21 JBrowse link 12 36,065,267 36,065,358 RGD:9068941
G MMP1 matrix metallopeptidase 1 JBrowse link 9 33,411,738 33,420,205 RGD:9068941
G MMP2 matrix metallopeptidase 2 JBrowse link 6 30,059,247 30,087,031 RGD:9068941
G MTHFR methylenetetrahydrofolate reductase JBrowse link 6 71,863,637 71,882,118 RGD:9068941
G NECTIN2 nectin cell adhesion molecule 2 JBrowse link 6 51,317,386 51,358,665 RGD:9068941
G NGF nerve growth factor JBrowse link 4 105,256,691 105,307,843 RGD:9068941
G NGFR nerve growth factor receptor JBrowse link 12 25,699,410 25,720,355 RGD:9068941
G NOD2 nucleotide binding oligomerization domain containing 2 JBrowse link 6 34,132,127 34,167,446 RGD:9068941
G NOS2 nitric oxide synthase 2 JBrowse link 12 44,174,944 44,219,875 RGD:9068941
G NOS3 nitric oxide synthase 3 JBrowse link 18 6,209,218 6,228,912 RGD:9068941
G NPC1 NPC intracellular cholesterol transporter 1 JBrowse link 6 108,403,126 108,450,486 RGD:9068941
G NPPB natriuretic peptide B JBrowse link 6 71,930,374 71,931,843 RGD:9068941
G NPY neuropeptide Y JBrowse link 18 47,985,796 47,993,726 RGD:9068941
G NPY1R neuropeptide Y receptor Y1 JBrowse link 8 52,152,649 52,163,080 RGD:9068941
G NPY2R neuropeptide Y receptor Y2 JBrowse link 8 74,039,959 74,048,398 RGD:9068941
G NPY5R neuropeptide Y receptor Y5 JBrowse link 8 52,173,906 52,183,336 RGD:9068941
G NR1H4 nuclear receptor subfamily 1 group H member 4 JBrowse link 5 83,607,222 83,732,668 RGD:9068941
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 10 14,203,157 14,241,164 RGD:9068941
G PDGFRB platelet derived growth factor receptor beta JBrowse link 2 151,155,753 151,192,818 RGD:9068941
G PECAM1 platelet and endothelial cell adhesion molecule 1 JBrowse link 12 14,667,643 14,723,296 RGD:9068941
G PGF placental growth factor JBrowse link 7 98,149,510 98,162,784 RGD:9068941
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma JBrowse link 9 106,698,200 106,748,217 RGD:9068941
G PLA2G2A phospholipase A2 group IIA JBrowse link 6 78,327,728 78,339,546 RGD:9068941
G PLA2G7 phospholipase A2 group VII JBrowse link 7 41,488,152 41,531,383 RGD:9068941
G PLAT plasminogen activator, tissue type JBrowse link 17 11,195,599 11,223,821 RGD:9068941
G PLAU plasminogen activator, urokinase JBrowse link 14 76,629,313 76,635,173 RGD:9068941
G PLTP phospholipid transfer protein JBrowse link 17 48,089,789 48,101,604 RGD:9068941
G PON1 paraoxonase 1 JBrowse link 9 74,943,646 74,974,720 RGD:9068941
G PON3 paraoxonase 3 JBrowse link 9 74,983,040 75,017,947 RGD:9068941
G PPARG peroxisome proliferator activated receptor gamma JBrowse link 13 68,301,566 68,433,951 RGD:9068941
G PTGES3 prostaglandin E synthase 3 JBrowse link 5 22,000,335 22,022,830 RGD:9068941
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 9 127,850,164 127,858,866 RGD:9068941
G SELL selectin L JBrowse link 4 81,306,363 81,325,296 RGD:9068941
G SELP selectin P JBrowse link 4 81,376,804 81,401,240 RGD:9068941
G SERPINE1 serpin family E member 1 JBrowse link 3 8,863,738 8,871,572 RGD:9068941
G SIRT1 sirtuin 1 JBrowse link 14 71,091,167 71,126,351 RGD:9068941
G SOCS3 suppressor of cytokine signaling 3 JBrowse link 12 3,643,832 3,647,015 RGD:9068941
G SOD1 superoxide dismutase 1 JBrowse link 13 195,326,573 195,335,273 RGD:9068941
G SOD2 superoxide dismutase 2 JBrowse link 1 7,679,352 7,689,564 RGD:9068941
G STAT3 signal transducer and activator of transcription 3 JBrowse link 12 20,407,316 20,471,091 RGD:9068941
G TLR2 toll like receptor 2 JBrowse link 8 75,416,257 75,428,370 RGD:9068941
G TLR4 toll like receptor 4 JBrowse link 1 258,044,610 258,054,641 RGD:9068941
G TNF tumor necrosis factor JBrowse link 7 23,699,635 23,702,393 RGD:9068941
G TRIM28 tripartite motif containing 28 JBrowse link 6 63,094,382 63,101,532 RGD:9068941
G TRPV1 transient receptor potential cation channel subfamily V member 1 JBrowse link 12 49,676,536 49,709,634 RGD:9068941
G TTPA alpha tocopherol transfer protein JBrowse link 4 70,960,580 70,980,883 RGD:9068941
G UCN2 urocortin 2 JBrowse link 13 31,261,196 31,261,824 RGD:9068941
G VCAM1 vascular cell adhesion molecule 1 JBrowse link 4 117,496,914 117,511,211 RGD:9068941
G VDR vitamin D receptor JBrowse link 5 78,205,807 78,266,505 RGD:9068941
G VEGFA vascular endothelial growth factor A JBrowse link 7 38,746,393 38,762,282 RGD:9068941
G VEGFC vascular endothelial growth factor C JBrowse link 15 39,037,764 39,136,234 RGD:9068941
G VIM vimentin JBrowse link 10 43,516,441 43,526,172 RGD:9068941
aortic atherosclerosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APOE apolipoprotein E JBrowse link 6 51,373,113 51,375,333 RGD:9068941
G CAPN1 calpain 1 JBrowse link 2 6,997,513 7,024,410 RGD:9068941
Carotid Atherosclerosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FGF21 fibroblast growth factor 21 JBrowse link 6 54,082,653 54,084,532 RGD:9068941
G PCSK5 proprotein convertase subtilisin/kexin type 5 JBrowse link 1 228,854,587 229,308,054 RGD:9068941
G SIRT1 sirtuin 1 JBrowse link 14 71,091,167 71,126,351 RGD:9068941
Carotid Intimal Medial Thickness 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PPARG peroxisome proliferator activated receptor gamma JBrowse link 13 68,301,566 68,433,951 RGD:7240710
RGD:9068941
Peripheral Arterial Occlusive Disease 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC396684 serpin A3-5 JBrowse link 7 115,871,489 115,880,323 RGD:9068941
peripheral artery disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 13 124,633,906 124,646,237 RGD:9068941
G B2M beta-2-microglobulin JBrowse link 1 126,837,721 126,844,043 RGD:9068941
G BMP2 bone morphogenetic protein 2 JBrowse link 17 15,750,487 15,762,982 RGD:9068941
G BMP8A bone morphogenetic protein 8a JBrowse link 6 95,322,454 95,366,546 RGD:9068941
G MTHFR methylenetetrahydrofolate reductase JBrowse link 6 71,863,637 71,882,118 RGD:9068941
G NPY neuropeptide Y JBrowse link 18 47,985,796 47,993,726 RGD:9068941
G NPY1R neuropeptide Y receptor Y1 JBrowse link 8 52,152,649 52,163,080 RGD:9068941
G NPY2R neuropeptide Y receptor Y2 JBrowse link 8 74,039,959 74,048,398 RGD:9068941
G NPY5R neuropeptide Y receptor Y5 JBrowse link 8 52,173,906 52,183,336 RGD:9068941
G P2RY12 purinergic receptor P2Y12 JBrowse link 13 91,522,754 91,572,195 RGD:9068941
G SERPINE1 serpin family E member 1 JBrowse link 3 8,863,738 8,871,572 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 12431
    disease of anatomical entity 12113
      cardiovascular system disease 3271
        vascular disease 2342
          artery disease 1540
            arteriosclerosis 558
              atherosclerosis 127
                Carotid Atherosclerosis 3
                Carotid Intimal Medial Thickness 1 1
                Premature Atherosclerosis with Deafness, Nephropathy, Diabetes Mellitus, Photomyoclonus, and Degenerative Neurologic Disease 0
                aortic atherosclerosis 2
                cerebral atherosclerosis 0
                generalized atherosclerosis 0
                peripheral artery disease + 12
                renal artery atheroma 0
Path 2
Term Annotations click to browse term
  disease 12431
    disease of anatomical entity 12113
      cardiovascular system disease 3271
        vascular disease 2342
          artery disease 1540
            arteriosclerosis 558
              arteriosclerotic cardiovascular disease 127
                atherosclerosis 127
                  Carotid Atherosclerosis 3
                  Carotid Intimal Medial Thickness 1 1
                  Premature Atherosclerosis with Deafness, Nephropathy, Diabetes Mellitus, Photomyoclonus, and Degenerative Neurologic Disease 0
                  aortic atherosclerosis 2
                  cerebral atherosclerosis 0
                  generalized atherosclerosis 0
                  peripheral artery disease + 12
                  renal artery atheroma 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.