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ONTOLOGY REPORT - ANNOTATIONS


Term:atherosclerosis
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Accession:DOID:1936 term browser browse the term
Definition:A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
Synonyms:exact_synonym: ALP;   ATHEROGENIC LIPOPROTEIN PHENOTYPE;   ATHEROSCLEROSIS SUSCEPTIBILITY;   ATHS;   Atherogenesis;   Atheroscleroses;   Atherosclerosis, Susceptibility To
 primary_id: MESH:D050197;   RDO:0007568
 alt_id: OMIM:108725
 xref: ICD10CM:I25.1;   ICD10CM:I70;   ICD9CM:440;   NCI:C35768;   NCI:C35771
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants       view all columns           Sort by:
 
atherosclerosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca1 ATP binding cassette subfamily A member 1 JBrowse link 5 69,857,717 69,983,042 RGD:11554173
G Abcg5 ATP binding cassette subfamily G member 5 JBrowse link 6 7,935,771 7,961,207 RGD:11554173
G Add1 adducin 1 JBrowse link 14 81,367,466 81,426,610 RGD:5147995
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:8694473
RGD:11554173
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:6784514
RGD:11554173
RGD:8695994
RGD:7245947
RGD:6767557
RGD:6784516
RGD:6784515
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:8549467
RGD:11554173
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:11554173
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:5509083
G Alox15 arachidonate 15-lipoxygenase JBrowse link 10 56,953,692 56,962,145 RGD:5509610
RGD:11554173
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:11554173
G Alox5ap arachidonate 5-lipoxygenase activating protein JBrowse link 12 6,854,930 6,879,112 RGD:11554173
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:7241575
RGD:7241852
G Apoa4 apolipoprotein A4 JBrowse link 8 50,536,983 50,539,371 RGD:11554173
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:734968
RGD:11554173
RGD:7771549
G Bcl3 BCL3, transcription coactivator JBrowse link 1 80,730,758 80,745,273 RGD:11554173
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:13792600
G Casr calcium-sensing receptor JBrowse link 11 67,188,204 67,262,261 RGD:7205454
RGD:7205672
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:8662275
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:8548896
RGD:11554173
RGD:7401235
G Ccl3 C-C motif chemokine ligand 3 JBrowse link 10 70,869,516 70,871,066 RGD:11554173
G Ccl4 C-C motif chemokine ligand 4 JBrowse link 10 70,870,926 70,886,357 RGD:11554173
G Ccr5 C-C motif chemokine receptor 5 JBrowse link 8 133,192,398 133,215,599 RGD:8549763
G Ccr6 C-C motif chemokine receptor 6 JBrowse link 1 53,063,380 53,087,519 RGD:7483610
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:6893502
RGD:11041151
RGD:6893559
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:5490534
RGD:8547801
RGD:1582628
G Cd40lg CD40 ligand JBrowse link X 159,703,703 159,714,886 RGD:5490529
RGD:11344965
RGD:8547801
RGD:1582628
RGD:7248421
G Cela2a chymotrypsin like elastase 2A JBrowse link 5 160,374,031 160,383,782 RGD:11554173
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:9068390
G Cnr2 cannabinoid receptor 2 JBrowse link 5 154,242,010 154,268,126 RGD:11554173
G Col4a2 collagen type IV alpha 2 chain JBrowse link 16 83,386,388 83,522,169 RGD:13450936
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:9491769
RGD:11554173
G Csf1 colony stimulating factor 1 JBrowse link 2 210,522,370 210,550,546 RGD:734837
RGD:7257575
G Ctsb cathepsin B JBrowse link 15 46,316,741 46,337,613 RGD:5687152
G Ctsd cathepsin D JBrowse link 1 215,541,570 215,553,446 RGD:5687152
G Ctsl cathepsin L JBrowse link 17 1,873,105 1,879,266 RGD:5687152
G Ctss cathepsin S JBrowse link 2 197,655,780 197,679,768 RGD:5687152
G Cx3cr1 C-X3-C motif chemokine receptor 1 JBrowse link 8 128,740,756 128,754,514 RGD:9479739
G Cyba cytochrome b-245 alpha chain JBrowse link 19 55,249,634 55,257,824 RGD:11554173
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 JBrowse link 9 81,968,285 81,998,213 RGD:11554173
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:8661682
G Egln1 egl-9 family hypoxia-inducible factor 1 JBrowse link 19 57,660,194 57,701,158 RGD:11251766
G Ephx2 epoxide hydrolase 2 JBrowse link 15 42,757,241 42,794,211 RGD:5688357
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:8553067
RGD:11554173
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:5508792
G F11r F11 receptor JBrowse link 13 89,826,272 89,850,151 RGD:7488921
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:7387315
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:13792600
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:11554173
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:5147923
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:7240526
G Fgf21 fibroblast growth factor 21 JBrowse link 1 101,595,579 101,596,822 RGD:10401919
G Grn granulin precursor JBrowse link 10 90,377,103 90,383,207 RGD:5509781
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:11554173
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:10402182
G Hnrnpc heterogeneous nuclear ribonucleoprotein C JBrowse link 15 28,486,605 28,517,353 RGD:10054381
G Hp haptoglobin JBrowse link 19 42,096,255 42,100,805 RGD:11041860
RGD:11554173
G Hrh1 histamine receptor H 1 JBrowse link 4 146,374,596 146,458,148 RGD:11554173
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:5147595
RGD:7257649
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:11554173
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:11554173
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:11554173
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:11554173
G Il17a interleukin 17A JBrowse link 9 26,841,299 26,844,786 RGD:9170237
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:8655997
RGD:14695532
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:7175328
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:5147904
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:11554173
G Kdr kinase insert domain receptor JBrowse link 14 34,727,677 34,787,127 RGD:8551768
G Kl Klotho JBrowse link 12 942,974 987,206 RGD:10403056
G Ldlr low density lipoprotein receptor JBrowse link 8 22,750,425 22,773,305 RGD:5490255
RGD:11554173
RGD:12910105
G Lta4h leukotriene A4 hydrolase JBrowse link 7 34,288,333 34,320,243 RGD:11554173
G Mir146a microRNA 146a JBrowse link 10 28,962,476 28,962,570 RGD:21081515
G Mir155 microRNA 155 JBrowse link 11 24,176,603 24,176,667 RGD:21079445
RGD:24922209
RGD:21081515
RGD:21079446
G Mir21 microRNA 21 JBrowse link 10 73,902,210 73,902,301 RGD:21081515
G Mir223 microRNA 223 JBrowse link X 65,367,812 65,367,921 RGD:25824846
G Mmp1 matrix metallopeptidase 1 JBrowse link 8 5,703,206 5,723,593 RGD:7207025
RGD:11554173
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:1582628
RGD:8657031
G Mthfr methylenetetrahydrofolate reductase JBrowse link 5 164,844,642 164,864,360 RGD:6893579
G Nectin2 nectin cell adhesion molecule 2 JBrowse link 1 80,631,449 80,666,617 RGD:11554173
G Ngf nerve growth factor JBrowse link 2 204,886,158 204,939,523 RGD:5508382
G Ngfr nerve growth factor receptor JBrowse link 10 83,389,828 83,408,061 RGD:5508382
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 19 19,342,061 19,389,366 RGD:8158039
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:11554173
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:7771564
RGD:11554173
RGD:7771607
G Npc1 NPC intracellular cholesterol transporter 1 JBrowse link 18 3,616,878 3,662,656 RGD:11554173
G Nppb natriuretic peptide B JBrowse link 5 164,796,176 164,797,538 RGD:7247628
RGD:7248594
G Npy neuropeptide Y JBrowse link 4 79,557,856 79,565,059 RGD:10448273
G Npy1r neuropeptide Y receptor Y1 JBrowse link 16 24,779,480 24,789,131 RGD:10448273
G Npy2r neuropeptide Y receptor Y2 JBrowse link 2 181,528,949 181,538,145 RGD:10448273
G Npy5r neuropeptide Y receptor Y5 JBrowse link 16 24,796,685 24,805,730 RGD:10448273
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:11554173
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:5683916
RGD:11554173
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:10449506
G Pecam1 platelet and endothelial cell adhesion molecule 1 JBrowse link 10 94,850,971 94,913,202 RGD:6771176
RGD:6771359
RGD:6771223
G Pgf placental growth factor JBrowse link 6 108,994,016 109,004,598 RGD:6483589
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma JBrowse link 6 51,465,696 51,501,234 RGD:1642394
G Pla2g2a phospholipase A2 group IIA JBrowse link 5 157,282,650 157,285,295 RGD:11554173
G Pla2g7 phospholipase A2 group VII JBrowse link 9 19,935,754 19,978,013 RGD:6482784
RGD:7248796
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:11554173
G Plau plasminogen activator, urokinase JBrowse link 15 3,644,296 3,650,765 RGD:7241201
RGD:7241203
G Pltp phospholipid transfer protein JBrowse link 3 161,304,469 161,322,289 RGD:1581039
G Pon1 paraoxonase 1 JBrowse link 4 30,249,749 30,276,297 RGD:5509927
RGD:11554173
RGD:11552582
RGD:8547574
RGD:8547562
G Pon3 paraoxonase 3 JBrowse link 4 30,311,981 30,338,679 RGD:5509927
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:8552894
RGD:11554173
G Ptges3 prostaglandin E synthase 3 JBrowse link 7 2,479,267 2,497,024 RGD:5688075
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:11554173
G Sell selectin L JBrowse link 13 82,369,820 82,387,774 RGD:5685675
G Selp selectin P JBrowse link 13 82,428,914 82,464,629 RGD:6478699
RGD:6480102
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:11554173
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:9585743
RGD:11554173
G Socs3 suppressor of cytokine signaling 3 JBrowse link 10 106,973,863 106,976,969 RGD:11554173
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:8655856
RGD:11554173
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:11554173
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:11554173
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:8552973
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:11554173
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:7401235
RGD:11554173
G Trim28 tripartite motif-containing 28 JBrowse link 1 65,544,369 65,551,043 RGD:11554173
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 10 59,799,123 59,824,208 RGD:11554173
G Ttpa alpha tocopherol transfer protein JBrowse link 5 34,007,926 34,029,315 RGD:11554173
G Ucn2 urocortin 2 JBrowse link 8 117,727,216 117,728,765 RGD:5508308
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 2 219,071,193 219,090,931 RGD:11554173
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:14402022
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:11554173
RGD:8554872
G Vegfc vascular endothelial growth factor C JBrowse link 16 40,440,371 40,555,178 RGD:7483588
G Vim vimentin JBrowse link 17 80,882,715 80,891,200 RGD:6480618
aortic atherosclerosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:13703129
G Capn1 calpain 1 JBrowse link 1 221,346,081 221,370,965 RGD:13792498
G Mir223 microRNA 223 JBrowse link X 65,367,812 65,367,921 RGD:25824846
Carotid Atherosclerosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf21 fibroblast growth factor 21 JBrowse link 1 101,595,579 101,596,822 RGD:10401924
G Pcsk5 proprotein convertase subtilisin/kexin type 5 JBrowse link 1 236,031,988 236,313,858 RGD:11556214
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:9495924
Carotid Intimal Medial Thickness 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:7240710
Peripheral Arterial Occlusive Disease 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Serpina3m serine (or cysteine) proteinase inhibitor, clade A, member 3M JBrowse link 6 127,808,785 127,816,067 RGD:8554872
peripheral artery disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:5686716
G B2m beta-2 microglobulin JBrowse link 3 114,087,287 114,093,311 RGD:6482704
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:11554173
G Bmp8a bone morphogenetic protein 8a JBrowse link 5 141,007,462 141,033,511 RGD:11554173
G Mthfr methylenetetrahydrofolate reductase JBrowse link 5 164,844,642 164,864,360 RGD:6893659
G Npy neuropeptide Y JBrowse link 4 79,557,856 79,565,059 RGD:10448273
G Npy1r neuropeptide Y receptor Y1 JBrowse link 16 24,779,480 24,789,131 RGD:10448273
G Npy2r neuropeptide Y receptor Y2 JBrowse link 2 181,528,949 181,538,145 RGD:10448273
G Npy5r neuropeptide Y receptor Y5 JBrowse link 16 24,796,685 24,805,730 RGD:10448273
G P2ry12 purinergic receptor P2Y12 JBrowse link 2 149,440,807 149,482,592 RGD:1580188
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:8547710

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15849
    disease of anatomical entity 15241
      cardiovascular system disease 4348
        vascular disease 3309
          artery disease 2269
            arteriosclerosis 618
              atherosclerosis 155
                Carotid Atherosclerosis 3
                Carotid Intimal Medial Thickness 1 1
                Premature Atherosclerosis with Deafness, Nephropathy, Diabetes Mellitus, Photomyoclonus, and Degenerative Neurologic Disease 0
                aortic atherosclerosis 3
                cerebral atherosclerosis 0
                generalized atherosclerosis 0
                peripheral artery disease + 12
                renal artery atheroma 0
Path 2
Term Annotations click to browse term
  disease 15849
    disease of anatomical entity 15241
      cardiovascular system disease 4348
        vascular disease 3309
          artery disease 2269
            arteriosclerosis 618
              arteriosclerotic cardiovascular disease 155
                atherosclerosis 155
                  Carotid Atherosclerosis 3
                  Carotid Intimal Medial Thickness 1 1
                  Premature Atherosclerosis with Deafness, Nephropathy, Diabetes Mellitus, Photomyoclonus, and Degenerative Neurologic Disease 0
                  aortic atherosclerosis 3
                  cerebral atherosclerosis 0
                  generalized atherosclerosis 0
                  peripheral artery disease + 12
                  renal artery atheroma 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.