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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:rectum adenocarcinoma
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Accession:DOID:1996 term browser browse the term
Definition:A rectum cancer that derives_from epithelial cells of glandular origin. (DO)
Synonyms:exact_synonym: rectal adenocarcinoma
 related_synonym: adenocarcinoma of rectum
 primary_id: RDO:9004073
 xref: NCI:C9383
For additional species annotation, visit the Alliance of Genome Resources.


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rectum adenocarcinoma term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway ISO ClinVar Annotator: match by term: Rectal Adenocarcinoma ClinVar PMID:24033266, PMID:25741868, PMID:26530882, PMID:28195569, PMID:28492532, PMID:30111351, PMID:30833958 NCBI chr18:27,011,710...27,106,323
Ensembl chr18:27,047,382...27,105,531
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Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16103
    disease of cellular proliferation 5912
      cancer 4235
        cell type cancer 3105
          carcinoma 2109
            colorectal carcinoma 70
              colorectal adenocarcinoma 51
                rectum adenocarcinoma 1
                  rectum mucinous adenocarcinoma 0
                  rectum signet ring adenocarcinoma 0
Path 2
Term Annotations click to browse term
  disease 16103
    disease of cellular proliferation 5912
      Neoplasms by Site 5277
        Digestive System Neoplasms 1908
          Gastrointestinal Neoplasms 1768
            Intestinal Neoplasms 690
              intestinal cancer 249
                large intestine cancer 245
                  colorectal cancer 245
                    colorectal carcinoma 70
                      colorectal adenocarcinoma 51
                        rectum adenocarcinoma 1
                          rectum mucinous adenocarcinoma 0
                          rectum signet ring adenocarcinoma 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.