ONTOLOGY REPORT - ANNOTATIONS


Term:anxiety disorder
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Accession:DOID:2030 term browser browse the term
Definition:Persistent and disabling ANXIETY.
Synonyms:exact_synonym: ANXIETY;   Anxiety Neuroses;   Neurotic Anxiety State;   Neurotic Anxiety States;   anxiety disorders;   anxiety state
 narrow_synonym: HARM AVOIDANCE
 related_synonym: SEROTONIN TRANSPORTER ACTIVITY, INCREASED/DECREASED
 primary_id: MESH:D001008;   RDO:0004782
 alt_id: OMIM:607834
For additional species annotation, visit the Alliance of Genome Resources.


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anxiety disorder term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adar adenosine deaminase, RNA-specific JBrowse link 2 189,045,551 189,085,448 RGD:8554872
G Adora2a adenosine A2a receptor JBrowse link 20 14,265,251 14,282,873 RGD:11554173
G Adra2a adrenoceptor alpha 2A JBrowse link 1 274,766,283 274,769,083 RGD:6480479
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:11554173
G Cartpt CART prepropeptide JBrowse link 2 30,125,249 30,127,408 RGD:11554173
G Ccr2 C-C motif chemokine receptor 2 RGD:8661781
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit JBrowse link 8 59,561,817 59,590,172 RGD:11554173
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit JBrowse link 2 189,088,570 189,096,785 RGD:11554173
G Cnr1 cannabinoid receptor 1 JBrowse link 5 49,307,584 49,333,064 RGD:11554173
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:11554173
G Crhr1 corticotropin releasing hormone receptor 1 JBrowse link 10 92,191,473 92,233,662 RGD:11554173
G Crhr2 corticotropin releasing hormone receptor 2 JBrowse link 4 85,286,371 85,329,374 RGD:11554173
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:9491832
RGD:11554173
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 JBrowse link 12 11,641,500 11,677,818 RGD:5685599
G Dixdc1 DIX domain containing 1 JBrowse link 8 55,091,232 55,164,636 RGD:11554173
G Dnmt1 DNA methyltransferase 1 JBrowse link 8 21,922,515 21,968,495 RGD:11554173
G Dnmt3b DNA methyltransferase 3 beta JBrowse link 3 149,131,541 149,170,061 RGD:9588317
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:1358603
RGD:11554173
G Eomes eomesodermin JBrowse link 8 127,144,367 127,152,618 RGD:11554173
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:7364908
RGD:10045678
G Fmr1 fragile X mental retardation 1 JBrowse link X 154,684,924 154,722,369 RGD:11554173
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:11554173
G Gabra2 gamma-aminobutyric acid type A receptor alpha2 subunit JBrowse link 14 39,662,411 39,801,082 RGD:11554173
G Gad1 glutamate decarboxylase 1 JBrowse link 3 56,861,440 56,902,139 RGD:6480264
G Glo1 glyoxalase 1 JBrowse link 20 9,273,589 9,291,608 RGD:11554173
G Gnb1 G protein subunit beta 1 JBrowse link 5 172,914,025 172,981,403 RGD:11554173
G Grm8 glutamate metabotropic receptor 8 JBrowse link 4 54,474,344 55,409,526 RGD:11554173
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 JBrowse link 2 50,099,576 50,499,799 RGD:9686419
G Hdac2 histone deacetylase 2 JBrowse link 20 43,084,870 43,108,198 RGD:9590265
G Htr1a 5-hydroxytryptamine receptor 1A JBrowse link 2 36,246,628 36,247,896 RGD:5683629
RGD:13592920
G Htr1b 5-hydroxytryptamine receptor 1B JBrowse link 8 89,113,984 89,130,830 RGD:625756
G Htr2c 5-hydroxytryptamine receptor 2C JBrowse link X 118,084,520 118,318,040 RGD:1625000
G Htr7 5-hydroxytryptamine receptor 7 JBrowse link 1 254,547,964 254,671,811 RGD:6482189
RGD:11554173
G Kdm3b lysine demethylase 3B JBrowse link 18 27,593,823 27,631,129 RGD:9590119
G L1cam L1 cell adhesion molecule JBrowse link X 156,901,244 156,928,064 RGD:6483075
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 JBrowse link 4 10,995,241 12,472,423 RGD:11554173
G Mdk midkine JBrowse link 3 80,841,003 80,843,895 RGD:11554173
G Mecp2 methyl CpG binding protein 2 JBrowse link X 156,650,389 156,713,813 RGD:11554173
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:11554173
G Mir34a microRNA 34a JBrowse link 5 167,092,491 167,092,592 RGD:11554173
G Ncor1 nuclear receptor co-repressor 1 JBrowse link 10 48,629,121 48,772,890 RGD:5688287
G Nps neuropeptide S JBrowse link 1 207,508,414 207,512,195 RGD:11554173
G Npy neuropeptide Y JBrowse link 4 79,557,856 79,565,059 RGD:6480264
RGD:11554173
G Npy1r neuropeptide Y receptor Y1 JBrowse link 16 24,779,480 24,789,131 RGD:10448284
RGD:11554173
G Oxt oxytocin/neurophysin I prepropeptide JBrowse link 3 123,106,694 123,107,534 RGD:11554173
G Pam peptidylglycine alpha-amidating monooxygenase JBrowse link 9 111,028,543 111,177,588 RGD:11554173
G Rai1 retinoic acid induced 1 JBrowse link 10 46,511,271 46,571,591 RGD:11554173
G Serpina1 serpin family A member 1 JBrowse link 6 127,610,241 127,632,265 RGD:11554173
G Shank1 SH3 and multiple ankyrin repeat domains 1 JBrowse link 1 100,297,137 100,344,377 RGD:11554173
G Slc6a3 solute carrier family 6 member 3 JBrowse link 1 32,323,011 32,363,983 RGD:11554173
G Slc6a4 solute carrier family 6 member 4 JBrowse link 10 63,153,656 63,188,377 RGD:4889509
RGD:8554872
RGD:11554173
RGD:7240710
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:11554173
G Ucn urocortin JBrowse link 6 26,602,144 26,602,974 RGD:11554173
acute stress disorder term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ache acetylcholinesterase JBrowse link 12 22,472,358 22,477,052 RGD:5509849
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:9585647
dopamine beta-hydroxylase deficiency term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dbh dopamine beta-hydroxylase JBrowse link 3 5,709,236 5,731,895 RGD:7240710
RGD:8554872
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:5685690
generalized anxiety disorder term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Zfp462 zinc finger protein 462 JBrowse link 5 71,679,841 71,824,077 RGD:13592920
neurocirculatory asthenia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc6a2 solute carrier family 6 member 2 JBrowse link 19 15,391,682 15,431,274 RGD:1624278
obsessive-compulsive disorder term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:734644
G Cckbr cholecystokinin B receptor JBrowse link 1 170,262,218 170,272,298 RGD:11554173
G Comt catechol-O-methyltransferase JBrowse link 11 86,715,981 86,735,630 RGD:1300383
G Hoxb8 homeo box B8 JBrowse link 10 84,131,484 84,133,874 RGD:11554173
G Hras HRas proto-oncogene, GTPase JBrowse link 1 214,178,404 214,181,841 RGD:12738360
G Htr1d 5-hydroxytryptamine receptor 1D JBrowse link 5 154,780,958 154,801,505 RGD:11554173
G Htr2a 5-hydroxytryptamine receptor 2A JBrowse link 15 56,666,152 56,732,469 RGD:7240710
RGD:11554173
G Htr7 5-hydroxytryptamine receptor 7 JBrowse link 1 254,547,964 254,671,811 RGD:6482188
G Slc6a4 solute carrier family 6 member 4 JBrowse link 10 63,153,656 63,188,377 RGD:1624295
RGD:8554872
RGD:11554173
RGD:7240710
G Slitrk5 SLIT and NTRK-like family, member 5 JBrowse link 15 96,817,907 96,826,760 RGD:11554173
Orthostatic Hypotension term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:11554173
G Gnas GNAS complex locus JBrowse link 3 172,374,957 172,434,988 RGD:1580406
G Gnb3 G protein subunit beta 3 JBrowse link 4 157,352,558 157,359,237 RGD:1580406
G Mt-nd2 mitochondrially encoded NADH dehydrogenase 2 JBrowse link MT 3,904 4,942 RGD:1581056
G Oprd1 opioid receptor, delta 1 JBrowse link 5 150,288,126 150,323,063 RGD:11554173
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:11554173
Orthostatic Hypotension 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyb561 cytochrome b-561 JBrowse link 10 94,136,993 94,147,567 RGD:8554872
RGD:7240710
Orthostatic Intolerance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc6a2 solute carrier family 6 member 2 JBrowse link 19 15,391,682 15,431,274 RGD:7240710
RGD:8554872
RGD:11554173
panic disorder term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora1 adenosine A1 receptor JBrowse link 13 51,042,111 51,076,913 RGD:1331525
G Adora2a adenosine A2a receptor JBrowse link 20 14,265,251 14,282,873 RGD:11554173
G Adra2a adrenoceptor alpha 2A JBrowse link 1 274,766,283 274,769,083 RGD:11554173
G Cckbr cholecystokinin B receptor JBrowse link 1 170,262,218 170,272,298 RGD:1358454
RGD:11554173
G Comt catechol-O-methyltransferase JBrowse link 11 86,715,981 86,735,630 RGD:7240710
RGD:8554872
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:1358525
G Htr1a 5-hydroxytryptamine receptor 1A JBrowse link 2 36,246,628 36,247,896 RGD:5683630
RGD:5683631
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:11554173
G Maoa monoamine oxidase A JBrowse link X 6,554,698 6,620,722 RGD:1600723
G Mbl2 mannose binding lectin 2 JBrowse link 1 248,435,069 248,442,669 RGD:12910826
G Tph2 tryptophan hydroxylase 2 JBrowse link 7 58,042,279 58,149,220 RGD:5686356
phobic disorder term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:11554173
G Hras HRas proto-oncogene, GTPase JBrowse link 1 214,178,404 214,181,841 RGD:12738360
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:11554173
post-traumatic stress disorder term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:10054113
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:10054113
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:10059367
G Casp12 caspase 12 JBrowse link 8 2,658,892 2,686,160 RGD:13782181
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:13782181
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:13782181
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:5147887
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:10412309
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:5686336
G Ntrk2 neurotrophic receptor tyrosine kinase 2 JBrowse link 17 5,934,651 6,245,778 RGD:5684783
G Pdia3 protein disulfide isomerase family A, member 3 JBrowse link 3 113,376,983 113,400,707 RGD:13782181
G Wfs1 wolframin ER transmembrane glycoprotein JBrowse link 14 78,640,707 78,665,224 RGD:8694407
postural orthostatic tachycardia syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc6a2 solute carrier family 6 member 2 JBrowse link 19 15,391,682 15,431,274 RGD:13592920
separation anxiety disorder term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Drd4 dopamine receptor D4 JBrowse link 1 214,278,296 214,282,818 RGD:11554173
social phobia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cntnap2 contactin associated protein-like 2 JBrowse link 4 74,700,539 77,025,463 RGD:13450911
Vasovagal Syncope term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nppb natriuretic peptide B JBrowse link 5 164,796,176 164,797,538 RGD:7247623

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14823
    disease of anatomical entity 13997
      nervous system disease 9111
        central nervous system disease 6908
          brain disease 6412
            disease of mental health 4323
              anxiety disorder 152
                Neuroticism 0
                acute stress disorder + 17
                generalized anxiety disorder 1
                neurocirculatory asthenia + 11
                neurotic disorder 0
                obsessive-compulsive disorder + 10
                panic disorder + 11
                phobic disorder + 4
                post-traumatic stress disorder 12
                separation anxiety disorder 1
Path 2
Term Annotations click to browse term
  disease 14823
    disease of anatomical entity 13997
      nervous system disease 9111
        central nervous system disease 6908
          brain disease 6412
            disease of mental health 4323
              cognitive disorder 1890
                anxiety disorder 152
                  Neuroticism 0
                  acute stress disorder + 17
                  generalized anxiety disorder 1
                  neurocirculatory asthenia + 11
                  neurotic disorder 0
                  obsessive-compulsive disorder + 10
                  panic disorder + 11
                  phobic disorder + 4
                  post-traumatic stress disorder 12
                  separation anxiety disorder 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.