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ONTOLOGY REPORT - ANNOTATIONS


Term:hyperpituitarism
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Accession:DOID:2444 term browser browse the term
Definition:Disease of the glandular, anterior portion of the pituitary (PITUITARY GLAND, ANTERIOR) resulting in hypersecretion of ADENOHYPOPHYSEAL HORMONES such as GROWTH HORMONE; PROLACTIN; THYROTROPIN; LUTEINIZING HORMONE; FOLLICLE STIMULATING HORMONE ; and ADRENOCORTICOTROPIC HORMONE. Hyperpituitarism usually is caused by a functional ADENOMA.
Synonyms:exact_synonym: Inappropriate FSH Secretion Syndrome;   Inappropriate Follicle Stimulating Hormone Secretion;   Inappropriate LH Secretion Syndrome;   Inappropriate Luteinizing Hormone Secretion;   Inappropriate TSH Secretion Syndrome;   Inappropriate Thyroid Stimulating Hormone Secretion;   Pituitary FSH Hypersecretion;   Pituitary LH Hypersecretion;   Pituitary TSH Hypersecretion
 primary_id: MESH:D006964;   RDO:0004720
For additional species annotation, visit the Alliance of Genome Resources.


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acromegaly term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gh1 growth hormone 1 JBrowse link 10 94,486,204 94,488,181 RGD:11554173
G Gnas GNAS complex locus JBrowse link 3 172,374,957 172,434,988 RGD:11554173
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:11554173
Gigantism term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ankrd26 ankyrin repeat domain 26 JBrowse link 4 150,548,656 150,616,928 RGD:9681744
G Nsd1 nuclear receptor binding SET domain protein 1 JBrowse link 17 9,840,859 9,955,391 RGD:11568154
hyperprolactinemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc3 ATP binding cassette subfamily C member 3 JBrowse link 10 82,047,308 82,116,928 RGD:11535162
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:11554173
RGD:13506955
G Gad1 glutamate decarboxylase 1 JBrowse link 3 56,861,440 56,902,139 RGD:11554173
G Gnrh1 gonadotropin releasing hormone 1 JBrowse link 15 44,441,856 44,446,064 RGD:11554173
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 RGD:4889596
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 JBrowse link 2 200,712,895 200,722,429 RGD:4889559
G Lhb luteinizing hormone subunit beta JBrowse link 1 101,409,992 101,413,725 RGD:11554173
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:1601278
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:1642575
RGD:11554173
G Prlr prolactin receptor JBrowse link 2 60,131,410 60,325,686 RGD:7240710
RGD:8554872
G Slc6a3 solute carrier family 6 member 3 JBrowse link 1 32,323,011 32,363,983 RGD:13506955
G Srd5a1 steroid 5 alpha-reductase 1 JBrowse link 1 36,320,504 36,354,694 RGD:4891877
G Srd5a2 steroid 5 alpha-reductase 2 JBrowse link 6 25,279,635 25,315,501 RGD:4891877
G Th tyrosine hydroxylase JBrowse link 1 216,073,034 216,080,287 RGD:5128768
RGD:13506955
pituitary-dependent Cushing's disease term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aip aryl-hydrocarbon receptor-interacting protein JBrowse link 1 219,361,859 219,373,924 RGD:8554872
G Gnai2 G protein subunit alpha i2 JBrowse link 8 116,370,730 116,391,337 RGD:8554872
G Gnas GNAS complex locus JBrowse link 3 172,374,957 172,434,988 RGD:8554872
G Pomc proopiomelanocortin JBrowse link 6 28,382,937 28,388,771 RGD:11554173
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:11554173
G Scg5 secretogranin V JBrowse link 3 105,235,065 105,279,475 RGD:13592920
G Usp8 ubiquitin specific peptidase 8 JBrowse link 3 119,173,818 119,222,499 RGD:8554872
RGD:11554173
RAHMAN SYNDROME term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G H1f4 H1.4 linker histone, cluster member JBrowse link 17 43,734,461 43,735,120 RGD:8554872
RGD:7240710
Simpson-Golabi-Behmel syndrome type 1 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gpc3 glypican 3 JBrowse link X 139,579,268 139,947,093 RGD:7240710
RGD:8554872
G Gpc4 glypican 4 JBrowse link X 139,354,325 139,464,876 RGD:11554173
G Med12 mediator complex subunit 12 JBrowse link X 71,174,653 71,197,812 RGD:8554872
G Retsat retinol saturase JBrowse link 4 100,465,365 100,474,128 RGD:11554173
TATTON-BROWN-RAHMAN SYNDROME term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnmt3a DNA methyltransferase 3 alpha JBrowse link 6 28,205,375 28,346,052 RGD:7240710
RGD:8554872
Tenorio Syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rnf125 ring finger protein 125 JBrowse link 18 15,193,226 15,225,454 RGD:7240710
RGD:8554872
THAUVIN-ROBINET-FAIVRE SYNDROME term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fibp FGF1 intracellular binding protein JBrowse link 1 220,840,078 220,844,412 RGD:8554872
RGD:7240710

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15590
    disease of anatomical entity 14919
      endocrine system disease 4789
        pituitary gland disease 155
          hyperpituitarism 35
            Gigantism + 12
            acromegaly + 3
            hyperprolactinemia + 14
            pituitary-dependent Cushing's disease + 7
Path 2
Term Annotations click to browse term
  disease 15590
    disease of anatomical entity 14919
      nervous system disease 10196
        central nervous system disease 8075
          brain disease 7543
            thalamic disease 197
              hypothalamic disease 197
                pituitary gland disease 155
                  hyperpituitarism 35
                    Gigantism + 12
                    acromegaly + 3
                    hyperprolactinemia + 14
                    pituitary-dependent Cushing's disease + 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.