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ONTOLOGY REPORT - ANNOTATIONS


Term:germ cell cancer
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Accession:DOID:2994 term browser browse the term
Definition:A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from germ cells. (DO)
Synonyms:exact_synonym: germ cell cancers;   malignant tumor of the germ cell
 primary_id: RDO:9003427
 xref: NCI:C3708
For additional species annotation, visit the Alliance of Genome Resources.


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Aplasia Cutis Congenita with Epibulbar Dermoids term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cluap1 clusterin associated protein 1 JBrowse link 10 11,847,058 11,878,792 RGD:8554872
G Kras KRAS proto-oncogene, GTPase JBrowse link 4 179,482,562 179,515,483 RGD:8554872
RGD:7240710
G Nlrp5 NLR family, pyrin domain containing 5 JBrowse link 1 71,452,184 71,490,915 RGD:8554872
atypical teratoid rhabdoid tumor term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alk ALK receptor tyrosine kinase JBrowse link 6 22,696,415 23,203,791 RGD:8554872
G Atrx ATRX, chromatin remodeler JBrowse link X 76,820,110 76,979,155 RGD:8554872
G Derl3 derlin 3 JBrowse link 20 13,692,102 13,707,645 RGD:8554872
G Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 JBrowse link 20 13,679,955 13,702,821 RGD:7240710
RGD:8554872
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:8554872
choriocarcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf8 fibroblast growth factor 8 JBrowse link 1 265,492,949 265,498,965 RGD:2289339
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:2290454
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:2290454
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:2292200
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:2292200
G Timp3 TIMP metallopeptidase inhibitor 3 JBrowse link 7 23,543,125 23,594,170 RGD:2290418
dermoid cyst of ovary term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxo3 forkhead box O3 JBrowse link 20 46,428,078 46,519,156 RGD:13592920
dysgerminoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Amhr2 anti-Mullerian hormone receptor type 2 JBrowse link 7 144,052,202 144,060,678 RGD:2315651
G Brca1 BRCA1, DNA repair associated JBrowse link 10 89,394,821 89,455,093 RGD:8554872
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:2289660
G Inha inhibin subunit alpha JBrowse link 9 82,700,482 82,703,383 RGD:2290380
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 14 35,072,131 35,149,638 RGD:2292181
RGD:8554872
G Pou5f1 POU class 5 homeobox 1 JBrowse link 20 3,747,231 3,751,994 RGD:2292443
G Set SET nuclear proto-oncogene JBrowse link 19 58,420,635 58,422,153 RGD:8554872
G St14 suppression of tumorigenicity 14 JBrowse link 8 32,240,113 32,280,813 RGD:2315091
embryonal carcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Afp alpha-fetoprotein JBrowse link 14 19,141,755 19,159,919 RGD:2292041
G Ccna2 cyclin A2 JBrowse link 2 123,274,727 123,282,266 RGD:2293346
G Chek2 checkpoint kinase 2 JBrowse link 12 51,845,574 51,878,098 RGD:2298484
G Fgf8 fibroblast growth factor 8 JBrowse link 1 265,492,949 265,498,965 RGD:2289339
G Inha inhibin subunit alpha JBrowse link 9 82,700,482 82,703,383 RGD:2290380
G Pou5f1 POU class 5 homeobox 1 JBrowse link 20 3,747,231 3,751,994 RGD:2292433
RGD:2292431
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:2299891
embryonal rhabdomyosarcoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arid1a AT-rich interaction domain 1A JBrowse link 5 151,904,687 151,977,973 RGD:11554173
G Bcor BCL6 co-repressor JBrowse link X 11,570,155 11,692,022 RGD:11554173
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B JBrowse link 3 110,367,949 110,420,471 RGD:11554173
G Dmd dystrophin JBrowse link X 51,149,358 53,519,271 RGD:11554173
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:8554872
G Myod1 myogenic differentiation 1 JBrowse link 1 102,396,538 102,399,248 RGD:11554173
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 JBrowse link 12 40,895,515 40,955,999 RGD:8554872
G Setd2 SET domain containing 2, histone lysine methyltransferase JBrowse link 8 118,802,478 118,888,224 RGD:11554173
G Slc22a18 solute carrier family 22, member 18 JBrowse link 1 216,676,330 216,700,632 RGD:13592920
G Stk11 serine/threonine kinase 11 JBrowse link 7 12,440,751 12,457,513 RGD:8554872
endodermal sinus tumor term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Afp alpha-fetoprotein JBrowse link 14 19,141,755 19,159,919 RGD:2292040
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:2298800
G Fgf8 fibroblast growth factor 8 JBrowse link 1 265,492,949 265,498,965 RGD:2289339
G Sall4 spalt-like transcription factor 4 JBrowse link 3 165,520,155 165,538,176 RGD:11557983
G Wnt2b Wnt family member 2B JBrowse link 2 207,433,771 207,457,094 RGD:2298800
germinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Braf B-Raf proto-oncogene, serine/threonine kinase JBrowse link 4 67,389,331 67,520,549 RGD:2315865
G Ccnd2 cyclin D2 JBrowse link 4 159,674,885 159,697,207 RGD:2296039
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:2289698
G Cdkn2a_v1 cyclin-dependent kinase inhibitor 2A, variant 1 RGD:2289698
G Cdkn2a_v2 cyclin-dependent kinase inhibitor 2A, variant 2 RGD:2289698
G Mgp matrix Gla protein JBrowse link 4 170,856,783 170,860,105 RGD:2293578
G Pax5 paired box 5 JBrowse link 5 60,007,587 60,191,973 RGD:8554872
G Pdpn podoplanin JBrowse link 5 161,947,137 161,981,441 RGD:2292236
G Pms2 PMS1 homolog 2, mismatch repair system component JBrowse link 12 12,714,394 12,738,654 RGD:8554872
G Ptch1 patched 1 JBrowse link 17 1,032,242 1,085,885 RGD:8554872
gestational trophoblastic neoplasm term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ncr1 natural cytotoxicity triggering receptor 1 JBrowse link 1 73,178,917 73,226,504 RGD:8554872
G Pou5f1 POU class 5 homeobox 1 JBrowse link 20 3,747,231 3,751,994 RGD:11554173
Hydatidiform Mole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cga glycoprotein hormones, alpha polypeptide JBrowse link 5 50,362,491 50,393,368 RGD:2293636
G Khdc3 KH domain containing 3, subcortical maternal complex member JBrowse link 8 79,781,941 79,783,845 RGD:11554173
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:2293517
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:2290363
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:2293517
G Ncr1 natural cytotoxicity triggering receptor 1 JBrowse link 1 73,178,917 73,226,504 RGD:8554872
G Pdgfrb platelet derived growth factor receptor beta JBrowse link 18 56,364,586 56,406,381 RGD:2292200
Hydatidiform Mole, Invasive term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:2293517
Hydatidiform Mole, Recurrent, 2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Khdc3 KH domain containing 3, subcortical maternal complex member JBrowse link 8 79,781,941 79,783,845 RGD:7240710
RGD:8554872
Hydatidiform Mole, Recurrent, 3 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mei1 meiotic double-stranded break formation protein 1 JBrowse link 7 123,308,041 123,361,391 RGD:7240710
RGD:8554872
Hydatidiform Mole, Recurrent, 4 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RGD1563323 similar to hypothetical protein FLJ22531 JBrowse link 1 219,864,108 219,952,143 RGD:7240710
RGD:8554872
malignant ovarian germ cell neoplasm term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbl Cbl proto-oncogene JBrowse link 8 48,481,256 48,564,775 RGD:8554872
G Fancm FA complementation group M JBrowse link 6 86,823,195 86,877,067 RGD:8554872
ovarian germ cell cancer term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sall4 spalt-like transcription factor 4 JBrowse link 3 165,520,155 165,538,176 RGD:11556233
Ring Dermoid of Cornea term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pitx2 paired-like homeodomain 2 JBrowse link 2 233,602,732 233,621,059 RGD:7240710
RGD:8554872
seminoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccnd2 cyclin D2 JBrowse link 4 159,674,885 159,697,207 RGD:2289154
G Chek2 checkpoint kinase 2 JBrowse link 12 51,845,574 51,878,098 RGD:2298484
G Entpd6 ectonucleoside triphosphate diphosphohydrolase 6 JBrowse link 3 146,546,424 146,568,828 RGD:11554173
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:2290049
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:2290049
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link 14 82,272,322 82,287,739 RGD:11554173
G Fhit fragile histidine triad diadenosine triphosphatase JBrowse link 15 15,697,292 16,862,873 RGD:2289879
G Hmbs hydroxymethylbilane synthase JBrowse link 8 48,667,278 48,674,673 RGD:2301683
G Hras HRas proto-oncogene, GTPase JBrowse link 1 214,178,404 214,181,841 RGD:2314832
RGD:11554173
G Inha inhibin subunit alpha JBrowse link 9 82,700,482 82,703,383 RGD:2290380
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:2290460
G Jup junction plakoglobin JBrowse link 10 88,280,517 88,307,451 RGD:2291872
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 JBrowse link 11 32,498,260 32,511,202 RGD:1580497
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:1580497
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 14 35,072,131 35,149,638 RGD:2292181
G Kras KRAS proto-oncogene, GTPase JBrowse link 4 179,482,562 179,515,483 RGD:2314915
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:2315012
G Pdgfra platelet derived growth factor receptor alpha JBrowse link 14 35,527,926 35,581,130 RGD:2292154
G Pdpn podoplanin JBrowse link 5 161,947,137 161,981,441 RGD:2292234
G Plaat3 phospholipase A and acyltransferase 3 JBrowse link 1 222,844,238 222,877,180 RGD:2290002
G Pou5f1 POU class 5 homeobox 1 JBrowse link 20 3,747,231 3,751,994 RGD:2292429
RGD:2292433
RGD:2292432
G Prmt5 protein arginine methyltransferase 5 JBrowse link 15 33,156,508 33,165,893 RGD:2299953
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:2299891
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:2299975
G Tspy1 testis specific protein, Y-linked 1 JBrowse link Y 151,941 156,587 RGD:2315445
G Tymp thymidine phosphorylase JBrowse link 7 130,342,481 130,347,845 RGD:2293724
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:2315467
G Xrcc1 X-ray repair cross complementing 1 JBrowse link 1 81,412,635 81,441,680 RGD:2302576
G Zfp354a zinc finger protein 354A JBrowse link 10 36,586,495 36,600,172 RGD:2291889
spermatocytoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link 14 82,272,322 82,287,739 RGD:8554872
G Hras HRas proto-oncogene, GTPase JBrowse link 1 214,178,404 214,181,841 RGD:8554872
G Lrrc56 leucine rich repeat containing 56 JBrowse link 1 214,182,232 214,197,184 RGD:8554872
teratocarcinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Afp alpha-fetoprotein JBrowse link 14 19,141,755 19,159,919 RGD:2292041
G H19 H19, imprinted maternally expressed transcript (non-protein coding) JBrowse link 1 215,744,404 215,747,080 RGD:2306169
teratoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:2296025
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:2298800
G H19 H19, imprinted maternally expressed transcript (non-protein coding) JBrowse link 1 215,744,404 215,747,080 RGD:2306183
G Nanog Nanog homeobox JBrowse link 4 155,531,906 155,539,268 RGD:9681441
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 JBrowse link 10 81,657,152 81,666,542 RGD:2299072
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 JBrowse link 10 81,648,216 81,653,717 RGD:2299072
G Pgm1 phosphoglucomutase 1 JBrowse link 5 118,743,632 118,803,055 RGD:2299871
G Pgm3 phosphoglucomutase 3 JBrowse link 8 94,225,513 94,243,230 RGD:2299871
G Tdgf1 teratocarcinoma-derived growth factor 1 JBrowse link 8 119,215,266 119,220,909 RGD:11561895
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:2298558
G Tymp thymidine phosphorylase JBrowse link 7 130,342,481 130,347,845 RGD:2293724
G Wnt2b Wnt family member 2B JBrowse link 2 207,433,771 207,457,094 RGD:2298800
testicular germ cell cancer term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl10 BCL10, immune signaling adaptor JBrowse link 2 251,805,392 251,814,957 RGD:13592920
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link 14 82,272,322 82,287,739 RGD:13592920
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 14 35,072,131 35,149,638 RGD:13592920
G Stk11 serine/threonine kinase 11 JBrowse link 7 12,440,751 12,457,513 RGD:13592920
trophoblastic neoplasm term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ang angiogenin JBrowse link 15 28,022,926 28,028,636 RGD:2325706
G Kiss1 KiSS-1 metastasis-suppressor JBrowse link 13 50,529,506 50,537,603 RGD:2292132

Term paths to the root
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Term Annotations click to browse term
  disease 0
    disease of cellular proliferation 5805
      cancer 4120
        cell type cancer 2925
          germ cell cancer 93
            central nervous system germ cell tumor + 0
            dysgerminoma + 8
            embryonal cancer + 17
            extragonadal germ cell cancer + 0
            fallopian tube germ cell cancer + 0
            germ cell and embryonal cancer + 41
            germinoma + 43
            mixed germ cell cancer + 2
            ovarian germ cell cancer + 3
            pediatric germ cell cancer + 0
            seminoma + 30
            testicular germ cell cancer + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.