Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:granulosa cell tumor
go back to main search page
Accession:DOID:2999 term browser browse the term
Definition:A neoplasm composed entirely of GRANULOSA CELLS, occurring mostly in the OVARY. In the adult form, it may contain some THECA CELLS. This tumor often produces ESTRADIOL and INHIBIN. The excess estrogen exposure can lead to other malignancies in women and PRECOCIOUS PUBERTY in girls. In rare cases, granulosa cell tumors have been identified in the TESTES.
Synonyms:exact_synonym: Cancer of Granulosa Cells;   Granulosa Cell Cancer;   Granulosa Cell Cancers;   Granulosa Cell Tumors;   Granulosa Cells Cancer;   Granulosa Cells Cancers;   Granulosa cell neoplasm;   Granulosa cell tumor, adult type;   Granulosa cell tumor, somatic;   Granulosa cell tumour, sarcomatoid;   malignant granulosa cell neoplasm
 primary_id: MESH:D006106
 alt_id: RDO:0000751
 xref: NCI:C3070;   NCI:C4205
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants       view all columns           Sort by:
 
granulosa cell tumor term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AMH anti-Mullerian hormone JBrowse link 19 2,249,323 2,252,073 RGD:2315639
G BMP4 bone morphogenetic protein 4 JBrowse link 14 53,949,736 53,956,891 RGD:1643593
G CCND2 cyclin D2 JBrowse link 12 4,273,762 4,305,353 RGD:2289157
G CDKN2A cyclin dependent kinase inhibitor 2A JBrowse link 9 21,967,752 21,995,324 RGD:2296066
G CDKN2B cyclin dependent kinase inhibitor 2B JBrowse link 9 22,002,903 22,009,313 RGD:2296066
G CMKLR1 chemerin chemokine-like receptor 1 JBrowse link 12 108,288,044 108,339,347 RGD:11554173
G CTNNB1 catenin beta 1 JBrowse link 3 41,199,422 41,240,445 RGD:1643593
RGD:13592920
G FANCF FA complementation group F JBrowse link 11 22,622,533 22,625,823 RGD:2298508
RGD:11049141
G FHIT fragile histidine triad diadenosine triphosphatase JBrowse link 3 59,747,277 61,251,461 RGD:2298508
G FSHR follicle stimulating hormone receptor JBrowse link 2 48,953,161 49,154,527 RGD:2289157
G GNAI2 G protein subunit alpha i2 JBrowse link 3 50,227,068 50,259,362 RGD:8554872
G KIT KIT proto-oncogene, receptor tyrosine kinase JBrowse link 4 54,657,928 54,740,715 RGD:2302173
G LEPR leptin receptor JBrowse link 1 65,420,652 65,641,559 RGD:11554173
G LHCGR luteinizing hormone/choriogonadotropin receptor JBrowse link 2 48,686,774 48,755,724 RGD:2302176
RGD:2289157
G MGMT O-6-methylguanine-DNA methyltransferase JBrowse link 10 129,467,214 129,770,983 RGD:2317693
G PRKAR2B protein kinase cAMP-dependent type II regulatory subunit beta JBrowse link 7 107,044,705 107,161,811 RGD:2289157
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 186,671,791 186,680,423 RGD:2289157
G RARRES2 retinoic acid receptor responder 2 JBrowse link 7 150,338,329 150,341,685 RGD:11554173
G SGK1 serum/glucocorticoid regulated kinase 1 JBrowse link 6 134,169,246 134,318,112 RGD:2289157
G SMAD1 SMAD family member 1 JBrowse link 4 145,481,306 145,559,176 RGD:2299978
G SMAD5 SMAD family member 5 JBrowse link 5 136,132,845 136,182,734 RGD:2299978
G ST14 suppression of tumorigenicity 14 JBrowse link 11 130,159,782 130,210,362 RGD:2315091
G VEGFA vascular endothelial growth factor A JBrowse link 6 43,770,209 43,786,487 RGD:2315463
G WIF1 WNT inhibitory factor 1 JBrowse link 12 65,050,626 65,121,305 RGD:1643593
Granulosa Cell Tumor of the Ovary term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GNAI2 G protein subunit alpha i2 JBrowse link 3 50,227,068 50,259,362 RGD:8554872
Leydig cell tumor term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CDK4 cyclin dependent kinase 4 JBrowse link 12 57,747,727 57,752,310 RGD:2293582
G CDKN1B cyclin dependent kinase inhibitor 1B JBrowse link 12 12,717,270 12,722,383 RGD:2293582
G CGA glycoprotein hormones, alpha polypeptide JBrowse link 6 87,085,498 87,095,106 RGD:2293633
G ESR1 estrogen receptor 1 JBrowse link 6 151,654,148 152,129,619 RGD:2290041
G FLT1 fms related receptor tyrosine kinase 1 JBrowse link 13 28,300,346 28,495,128 RGD:2301251
G INHA inhibin subunit alpha JBrowse link 2 219,572,310 219,575,711 RGD:2290379
G LHB luteinizing hormone subunit beta JBrowse link 19 49,015,980 49,017,091 RGD:11554173
G LHCGR luteinizing hormone/choriogonadotropin receptor JBrowse link 2 48,686,774 48,755,724 RGD:2302176
RGD:11554173
RGD:2292537
G PDGFA platelet derived growth factor subunit A JBrowse link 7 497,245 520,668 RGD:2298579
G PDGFB platelet derived growth factor subunit B JBrowse link 22 39,223,359 39,244,982 RGD:2298579
G PDGFRA platelet derived growth factor receptor alpha JBrowse link 4 54,229,127 54,298,247 RGD:2298580
RGD:2298579
G PDGFRB platelet derived growth factor receptor beta JBrowse link 5 150,113,839 150,155,845 RGD:2298579
G PRL prolactin JBrowse link 6 22,287,246 22,302,897 RGD:11554173
G PRMT5 protein arginine methyltransferase 5 JBrowse link 14 22,920,526 22,929,392 RGD:2299953
multinodular goiter term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DICER1 dicer 1, ribonuclease III JBrowse link 14 95,086,228 95,158,263 RGD:8554872
RGD:7240710
Sertoli cell tumor term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G INHA inhibin subunit alpha JBrowse link 2 219,572,310 219,575,711 RGD:2290369
Sertoli-Leydig cell tumor term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G INHA inhibin subunit alpha JBrowse link 2 219,572,310 219,575,711 RGD:2290367
Somatic Leydig Cell Adenoma, with Male-Limited Precocious Puberty term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LHCGR luteinizing hormone/choriogonadotropin receptor JBrowse link 2 48,686,774 48,755,724 RGD:8554872
G STON1-GTF2A1L STON1-GTF2A1L readthrough JBrowse link 2 48,529,925 48,776,517 RGD:8554872

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16489
    disease of anatomical entity 15414
      endocrine system disease 4760
        endocrine gland cancer 1566
          ovarian cancer 241
            granulosa cell tumor 39
              Abrikosov's Tumor 0
              Granulosa Cell Tumor of the Ovary 1
              testicular granulosa cell tumor + 2
              testicular sex cord-stromal neoplasm + 16
Path 2
Term Annotations click to browse term
  disease 16489
    disease of anatomical entity 15414
      Urogenital Diseases 4318
        Female Urogenital Diseases and Pregnancy Complications 1867
          Female Urogenital Diseases 1562
            female reproductive system disease 1558
              Adnexal Diseases 676
                ovarian disease 670
                  Ovarian Neoplasms 396
                    ovarian cancer 241
                      granulosa cell tumor 39
                        Abrikosov's Tumor 0
                        Granulosa Cell Tumor of the Ovary 1
                        testicular granulosa cell tumor + 2
                        testicular sex cord-stromal neoplasm + 16
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.