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Term:Churg-Strauss syndrome
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Accession:DOID:3049 term browser browse the term
Definition:Widespread necrotizing angiitis with granulomas. Pulmonary involvement is frequent. Asthma or other respiratory infection may precede evidence of vasculitis. Eosinophilia and lung involvement differentiate this disease from POLYARTERITIS NODOSA.
Synonyms:exact_synonym: Allergic Angiitides;   Allergic Angiitis;   Allergic Angiitis and Granulomatosis;   Allergic Granulomatoses;   Allergic Granulomatosis;   Allergic Granulomatous Angiitides;   Allergic Granulomatous Angiitis;   Allergic Granulomatous and Angiitis;   Allergic granulomatosis angiitis;   Churg-Strauss Vasculitis;   Eosinophilic Granulomatous Vasculitides;   Eosinophilic Granulomatous Vasculitis
 primary_id: MESH:D015267;   RDO:0000082
 xref: ICD10CM:M30.1;   NCI:C34481
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Churg-Strauss syndrome term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl26 C-C motif chemokine ligand 26 JBrowse link 12 24,157,182 24,161,870 RGD:11081158
G Gdnf glial cell derived neurotrophic factor JBrowse link 2 56,884,181 56,912,964 RGD:6218983
G Gfra1 GDNF family receptor alpha 1 JBrowse link 1 279,203,046 279,572,789 RGD:6218983
G Il5 interleukin 5 JBrowse link 10 39,066,716 39,069,587 RGD:6892720
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:6892720
G Vtn vitronectin JBrowse link 10 65,767,960 65,771,040 RGD:1580817

Term paths to the root
Path 1
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  disease 16021
    syndrome 6144
      Churg-Strauss syndrome 6
Path 2
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  disease 16021
    disease of anatomical entity 15274
      Immune & Inflammatory Diseases 3421
        immune system disease 2807
          lymphatic system disease 1079
            lymphoproliferative syndrome 669
              Granuloma 31
                Churg-Strauss syndrome 6
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.