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Accession:DOID:3071 term browser browse the term
Definition:Rare mixed tumors of the brain and rarely the spinal cord which contain malignant neuroectodermal (glial) and mesenchymal components, including spindle-shaped fibrosarcoma cells. These tumors are highly aggressive and present primarily in adults as rapidly expanding mass lesions. They may arise in tissue that has been previously irradiated. (From Br J Neurosurg 1995 Apr;9(2):171-8)
Synonyms:exact_synonym: Glioblastoma with Sarcomatous Component;   Gliosarcomas;   Sarcomatous Glioma;   Sarcomatous Gliomas
 primary_id: MESH:D018316;   RDO:0007178
 xref: GARD:5653;   NCI:C3796
For additional species annotation, visit the Alliance of Genome Resources.

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gliosarcoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:11526112
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 JBrowse link 1 83,163,103 83,236,615 RGD:11554173
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 JBrowse link 1 258,074,797 258,139,176 RGD:11554173
G Plau plasminogen activator, urokinase JBrowse link 15 3,644,296 3,650,765 RGD:7241591
G Por cytochrome p450 oxidoreductase JBrowse link 12 23,998,411 24,017,063 RGD:11554173
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:5688250
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:5688250
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:11554173

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15620
    disease of cellular proliferation 5796
      cancer 4113
        cell type cancer 2920
          malignant glioma 1069
            gliosarcoma 8
Path 2
Term Annotations click to browse term
  disease 15620
    disease of anatomical entity 14949
      nervous system disease 10219
        central nervous system disease 8096
          brain disease 7565
            Brain Neoplasms 966
              Supratentorial Neoplasms 851
                supratentorial cancer 851
                  cerebrum cancer 788
                    astrocytoma 784
                      glioblastoma multiforme 151
                        gliosarcoma 8
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.