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ONTOLOGY REPORT - ANNOTATIONS


Term:oligodendroglioma
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Accession:DOID:3181 term browser browse the term
Definition:A relatively slow-growing glioma that is derived from oligodendrocytes and tends to occur in the cerebral hemispheres, thalamus, or lateral ventricle. They may present at any age, but are most frequent in the third to fifth decades, with an earlier incidence peak in the first decade. Histologically, these tumors are encapsulated, relatively avascular, and tend to form cysts and microcalcifications. Neoplastic cells tend to have small round nuclei surrounded by unstained nuclei. The tumors may vary from well-differentiated to highly anaplastic forms. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2052; Adams et al., Principles of Neurology, 6th ed, p655)
Synonyms:exact_synonym: Anaplastic Oligodendroglioma;   Anaplastic Oligodendrogliomas;   Mixed Oligodendroglioma Astrocytoma;   Mixed Oligodendroglioma Ependymoma;   Mixed Oligodendroglioma-Astrocytomas;   Mixed Oligodendroglioma-Ependymomas;   Oligodendroblastoma;   Oligodendroblastomas;   Oligodendrogliomas;   oligodendroglial neoplasm;   oligodendroglial tumor;   well differentiated oligodendroglioma;   well-differentiated oligodendrogliomas
 primary_id: MESH:D009837
 alt_id: RDO:0006230
 xref: GARD:9953;   NCI:C129319;   NCI:C6960
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oligodendroglioma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atrx ATRX, chromatin remodeler JBrowse link X 76,820,110 76,979,155 RGD:8554872
G Camk2b calcium/calmodulin-dependent protein kinase II beta JBrowse link 14 86,208,876 86,297,727 RGD:13702479
G Cic capicua transcriptional repressor JBrowse link 1 82,135,440 82,163,007 RGD:8554872
G Dtx1 deltex E3 ubiquitin ligase 1 JBrowse link 12 41,383,885 41,415,783 RGD:11554173
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:13702474
G Gdnf glial cell derived neurotrophic factor JBrowse link 2 56,884,181 56,912,964 RGD:11554173
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:11554173
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 JBrowse link 2 95,320,147 95,322,701 RGD:11554173
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 JBrowse link 9 71,882,108 71,911,645 RGD:11554173
RGD:8554872
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 JBrowse link 1 141,874,354 141,893,674 RGD:11554173
G Mgmt O-6-methylguanine-DNA methyltransferase JBrowse link 1 209,237,255 209,464,189 RGD:2317688
G Ptges3 prostaglandin E synthase 3 JBrowse link 7 2,479,267 2,497,024 RGD:5688067
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:13782064

Term paths to the root
Path 1
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  disease 0
    disease of cellular proliferation 5797
      cancer 4113
        cell type cancer 2921
          malignant glioma 1069
            oligodendroglioma 13
              adult oligodendroglioma 0
              brain oligodendroglioma + 0
              childhood oligodendroglioma 0
              corpus callosum oligodendroglioma 0
              spinal cord oligodendroglioma 0
Path 2
Term Annotations click to browse term
  disease 15626
    disease of anatomical entity 14956
      nervous system disease 10224
        Nervous System Neoplasms 1758
          nervous system cancer 1708
            neuroectodermal tumor 1614
              astroblastoma 1192
                malignant glioma 1069
                  oligodendroglioma 13
                    adult oligodendroglioma 0
                    brain oligodendroglioma + 0
                    childhood oligodendroglioma 0
                    corpus callosum oligodendroglioma 0
                    spinal cord oligodendroglioma 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.