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ONTOLOGY REPORT - ANNOTATIONS


Term:germinoma
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Accession:DOID:3304 term browser browse the term
Definition:A malignant neoplasm of the germinal tissue of the GONADS; MEDIASTINUM; or pineal region. Germinomas are uniform in appearance, consisting of large, round cells with vesicular nuclei and clear or finely granular eosinophilic-staining cytoplasm. (Stedman, 265th ed; from DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1642-3)
Synonyms:exact_synonym: Germinomas
 primary_id: MESH:D018237
 alt_id: RDO:0005406
 xref: NCI:C3753
For additional species annotation, visit the Alliance of Genome Resources.


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germinoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Braf B-Raf proto-oncogene, serine/threonine kinase JBrowse link 4 67,389,331 67,520,549 RGD:2315865
G Ccnd2 cyclin D2 JBrowse link 4 159,674,885 159,697,207 RGD:2296039
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:2289698
G Cdkn2a_v1 cyclin-dependent kinase inhibitor 2A, variant 1 RGD:2289698
G Cdkn2a_v2 cyclin-dependent kinase inhibitor 2A, variant 2 RGD:2289698
G Mgp matrix Gla protein JBrowse link 4 170,856,783 170,860,105 RGD:2293578
G Pax5 paired box 5 JBrowse link 5 60,007,587 60,191,973 RGD:8554872
G Pdpn podoplanin JBrowse link 5 161,947,137 161,981,441 RGD:2292236
G Pms2 PMS1 homolog 2, mismatch repair system component JBrowse link 12 12,714,394 12,738,654 RGD:8554872
G Ptch1 patched 1 JBrowse link 17 1,032,242 1,085,885 RGD:8554872
dysgerminoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Amhr2 anti-Mullerian hormone receptor type 2 JBrowse link 7 144,052,202 144,060,678 RGD:2315651
G Brca1 BRCA1, DNA repair associated JBrowse link 10 89,394,821 89,455,093 RGD:8554872
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:2289660
G Inha inhibin subunit alpha JBrowse link 9 82,700,482 82,703,383 RGD:2290380
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 14 35,072,131 35,149,638 RGD:2292181
RGD:8554872
G Pou5f1 POU class 5 homeobox 1 JBrowse link 20 3,747,231 3,751,994 RGD:2292443
G Set SET nuclear proto-oncogene JBrowse link 19 58,420,635 58,422,153 RGD:8554872
G St14 suppression of tumorigenicity 14 JBrowse link 8 32,240,113 32,280,813 RGD:2315091
seminoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccnd2 cyclin D2 JBrowse link 4 159,674,885 159,697,207 RGD:2289154
G Chek2 checkpoint kinase 2 JBrowse link 12 51,845,574 51,878,098 RGD:2298484
G Entpd6 ectonucleoside triphosphate diphosphohydrolase 6 JBrowse link 3 146,546,424 146,568,828 RGD:11554173
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:2290049
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:2290049
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link 14 82,272,322 82,287,739 RGD:11554173
G Fhit fragile histidine triad diadenosine triphosphatase JBrowse link 15 15,697,292 16,862,873 RGD:2289879
G Hmbs hydroxymethylbilane synthase JBrowse link 8 48,667,278 48,674,673 RGD:2301683
G Hras HRas proto-oncogene, GTPase JBrowse link 1 214,178,404 214,181,841 RGD:2314832
RGD:11554173
G Inha inhibin subunit alpha JBrowse link 9 82,700,482 82,703,383 RGD:2290380
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:2290460
G Jup junction plakoglobin JBrowse link 10 88,280,517 88,307,451 RGD:2291872
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 JBrowse link 11 32,498,260 32,511,202 RGD:1580497
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:1580497
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 14 35,072,131 35,149,638 RGD:2292181
G Kras KRAS proto-oncogene, GTPase JBrowse link 4 179,482,562 179,515,483 RGD:2314915
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:2315012
G Pdgfra platelet derived growth factor receptor alpha JBrowse link 14 35,527,926 35,581,130 RGD:2292154
G Pdpn podoplanin JBrowse link 5 161,947,137 161,981,441 RGD:2292234
G Plaat3 phospholipase A and acyltransferase 3 JBrowse link 1 222,844,238 222,877,180 RGD:2290002
G Pou5f1 POU class 5 homeobox 1 JBrowse link 20 3,747,231 3,751,994 RGD:2292429
RGD:2292433
RGD:2292432
G Prmt5 protein arginine methyltransferase 5 JBrowse link 15 33,156,508 33,165,893 RGD:2299953
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:2299891
G Smad4 SMAD family member 4 JBrowse link 18 69,626,682 69,657,373 RGD:2299975
G Tspy1 testis specific protein, Y-linked 1 JBrowse link Y 151,941 156,587 RGD:2315445
G Tymp thymidine phosphorylase JBrowse link 7 130,342,481 130,347,845 RGD:2293724
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:2315467
G Xrcc1 X-ray repair cross complementing 1 JBrowse link 1 81,412,635 81,441,680 RGD:2302576
G Zfp354a zinc finger protein 354A JBrowse link 10 36,586,495 36,600,172 RGD:2291889
spermatocytoma term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link 14 82,272,322 82,287,739 RGD:8554872
G Hras HRas proto-oncogene, GTPase JBrowse link 1 214,178,404 214,181,841 RGD:8554872
G Lrrc56 leucine rich repeat containing 56 JBrowse link 1 214,182,232 214,197,184 RGD:8554872

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15639
    disease of cellular proliferation 5805
      Neoplasms by Histologic Type 3584
        cell type cancer 2925
          germ cell cancer 93
            germinoma 43
              central nervous system germinoma + 0
              dysgerminoma + 8
              seminoma + 30
Path 2
Term Annotations click to browse term
  disease 15639
    disease of cellular proliferation 5805
      cancer 4120
        organ system cancer 3931
          nervous system cancer 1708
            central nervous system cancer 956
              brain cancer 940
                germinoma 43
                  central nervous system germinoma + 0
                  dysgerminoma + 8
                  seminoma + 30
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.