ONTOLOGY REPORT - ANNOTATIONS


Term:atopic dermatitis
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Accession:DOID:3310 term browser browse the term
Definition:A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.
Synonyms:exact_synonym: ATOD;   Allergic;   Atopic Eczema;   Atopic Neurodermatitides;   Atopic Neurodermatitis;   Besnier's prurigo;   Disseminated Neurodermatitides;   Disseminated Neurodermatitis;   allergic dermatitis;   atopic dermatitides;   infantile eczema
 primary_id: MESH:D003876
 alt_id: RDO:0005348
 xref: OMIM:PS603165
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atopic dermatitis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adam17 ADAM metallopeptidase domain 17 JBrowse link NW_004955487 5,180,241 5,218,298 RGD:9068941
G Apoe apolipoprotein E JBrowse link NW_004955555 1,998,170 2,002,003 RGD:9068941
G Bdnf brain derived neurotrophic factor JBrowse link NW_004955476 6,773,244 6,822,201 RGD:9068941
G C3 complement C3 JBrowse link NW_004955495 2,796,601 2,824,233 RGD:9068941
G Card11 caspase recruitment domain family member 11 JBrowse link NW_004955460 12,368,987 12,487,675 RGD:9068941
G Casp8 caspase 8 JBrowse link NW_004955403 322,082 348,591 RGD:9068941
G Ccdc80 coiled-coil domain containing 80 JBrowse link NW_004955427 12,945,230 12,975,020 RGD:9068941
G Ccl17 C-C motif chemokine ligand 17 JBrowse link NW_004955433 15,052,616 15,054,732 RGD:9068941
G Ccl20 C-C motif chemokine ligand 20 JBrowse link NW_004955453 6,846,625 6,850,007 RGD:9068941
G Ccl22 C-C motif chemokine ligand 22 JBrowse link NW_004955433 15,002,001 15,007,324 RGD:9068941
G Ccl24 C-C motif chemokine ligand 24 JBrowse link NW_004955456 14,582,812 14,588,574 RGD:9068941
G Ccl26 C-C motif chemokine ligand 26 JBrowse link NW_004955456 14,554,583 14,558,967 RGD:9068941
G Ccl27 C-C motif chemokine ligand 27 JBrowse link NW_004955472 1,470,407 1,474,800 RGD:9068941
G Ccl28 C-C motif chemokine ligand 28 JBrowse link NW_004955446 18,902,465 18,925,178 RGD:9068941
G Ccl5 C-C motif chemokine ligand 5 JBrowse link NW_004955481 10,293,758 10,301,118 RGD:9068941
G Ccr2 C-C motif chemokine receptor 2 JBrowse link NW_004955420 25,641,184 25,664,413 RGD:9068941
G Ccr3 C-C motif chemokine receptor 3 JBrowse link NW_004955420 25,702,917 25,723,269 RGD:9068941
G Cd40 CD40 molecule JBrowse link NW_004955445 11,191,817 11,202,156 RGD:9068941
G Cldn1 claudin 1 JBrowse link NW_004955420 17,798,974 17,815,049 RGD:9068941
G Cldn23 claudin 23 JBrowse link NW_004955463 4,740,476 4,742,283 RGD:9068941
G Ctla4 cytotoxic T-lymphocyte associated protein 4 JBrowse link NW_004955457 11,028,707 11,034,898 RGD:9068941
G Ctse cathepsin E JBrowse link NW_004955406 41,641,412 41,653,261 RGD:9068941
G Cx3cl1 C-X3-C motif chemokine ligand 1 JBrowse link NW_004955433 15,023,272 15,034,650 RGD:9068941
G Cx3cr1 C-X3-C motif chemokine receptor 1 JBrowse link NW_004955427 24,691,206 24,705,599 RGD:9068941
G Cxcl10 C-X-C motif chemokine ligand 10 JBrowse link NW_004955433 748,392 750,890 RGD:9068941
G Cxcr3 C-X-C motif chemokine receptor 3 JBrowse link NW_004955475 11,148,928 11,152,313 RGD:9068941
G Emsy EMSY transcriptional repressor, BRCA2 interacting JBrowse link NW_004955414 15,395,851 15,482,490 RGD:9068941
G F2 coagulation factor II, thrombin JBrowse link NW_004955422 1,356,675 1,367,788 RGD:9068941
G Glb1 galactosidase beta 1 JBrowse link NW_004955421 230,957 311,504 RGD:9068941
G Gstp1 glutathione S-transferase pi 1 JBrowse link NW_004955422 17,914,228 17,916,918 RGD:9068941
G Havcr1 hepatitis A virus cellular receptor 1 JBrowse link NW_004955408 11,047,679 11,070,492 RGD:9068941
G Hnmt histamine N-methyltransferase JBrowse link NW_004955440 5,084,198 5,137,577 RGD:9068941
G Ifng interferon gamma JBrowse link NW_004955458 14,643,333 14,648,020 RGD:9068941
G Il10 interleukin 10 JBrowse link NW_004955406 42,307,789 42,312,255 RGD:9068941
G Il13 interleukin 13 JBrowse link NW_004955408 4,046,406 4,049,795 RGD:9068941
G Il13ra1 interleukin 13 receptor subunit alpha 1 JBrowse link NW_004955534 1,157,758 1,205,158 RGD:9068941
G Il13ra2 interleukin 13 receptor subunit alpha 2 JBrowse link NW_004955490 708,144 758,195 RGD:9068941
G Il17a interleukin 17A JBrowse link NW_004955411 5,896,435 5,899,911 RGD:9068941
G Il18 interleukin 18 JBrowse link NW_004955412 13,807,361 13,826,007 RGD:9068941
G Il1b interleukin 1 beta JBrowse link NW_004955470 1,486,936 1,491,888 RGD:9068941
G Il2 interleukin 2 JBrowse link NW_004955428 18,163,010 18,168,157 RGD:9068941
G Il21r interleukin 21 receptor JBrowse link NW_004955493 5,613,704 5,646,692 RGD:9068941
G Il31 interleukin 31 JBrowse link NW_004955482 6,387,289 6,389,361 RGD:9068941
G Il33 interleukin 33 JBrowse link NW_004955434 10,145,449 10,187,595 RGD:9068941
G Il4 interleukin 4 JBrowse link NW_004955408 4,058,052 4,065,999 RGD:9068941
G Il4r interleukin 4 receptor JBrowse link NW_004955493 5,546,340 5,580,745 RGD:9068941
G Il5 interleukin 5 JBrowse link NW_004955408 3,937,128 3,951,784 RGD:9068941
G Il6 interleukin 6 JBrowse link NW_004955410 25,079,835 25,084,390 RGD:9068941
G Mapk8 mitogen-activated protein kinase 8 JBrowse link NW_004955556 1,593,552 1,705,543 RGD:9068941
G Mbl2 mannose binding lectin 2 JBrowse link NW_004955425 7,704,371 7,708,951 RGD:9068941
G Mmp9 matrix metallopeptidase 9 JBrowse link NW_004955445 11,295,500 11,303,322 RGD:9068941
G Ms4a2 membrane spanning 4-domains A2 JBrowse link NW_004955511 4,377,894 4,400,797 RGD:9068941
G Nfkbia NFKB inhibitor alpha JBrowse link NW_004955409 25,691,673 25,695,151 RGD:9068941
G Nfkbiz NFKB inhibitor zeta JBrowse link NW_004955427 3,350,174 3,358,609 RGD:9068941
G Ngf nerve growth factor JBrowse link NW_004955435 18,581,889 18,633,330 RGD:9068941
G Ngfr nerve growth factor receptor JBrowse link NW_004955451 12,030,303 12,047,305 RGD:9068941
G Ntrk1 neurotrophic receptor tyrosine kinase 1 JBrowse link NW_004955545 2,929,704 2,947,579 RGD:9068941
G Ovol1 ovo like transcriptional repressor 1 JBrowse link NW_004955422 19,524,420 19,528,938 RGD:9068941
G Ppara peroxisome proliferator activated receptor alpha JBrowse link NW_004955413 30,306,563 30,366,245 RGD:9068941
G Relb RELB proto-oncogene, NF-kB subunit JBrowse link NW_004955555 2,060,533 2,086,229 RGD:9068941
G Sele selectin E JBrowse link NW_004955462 7,564,437 7,575,297 RGD:9068941
G Selp selectin P JBrowse link NW_004955462 7,658,371 7,692,870 RGD:9068941
G Sharpin SHANK associated RH domain interactor JBrowse link NW_004955454 2,761,725 2,765,929 RGD:9068941
G Slc11a1 solute carrier family 11 member 1 JBrowse link NW_004955453 14,980,562 14,995,118 RGD:9068941
G Stat6 signal transducer and activator of transcription 6 JBrowse link NW_004955458 4,833,417 4,847,956 RGD:9068941
G Tgfb1 transforming growth factor beta 1 JBrowse link NW_004955555 274,405 288,441 RGD:9068941
G Tlr2 toll like receptor 2 JBrowse link NW_004955471 8,011,710 8,019,063 RGD:9068941
G Tlr4 toll like receptor 4 JBrowse link NW_004955419 10,190,937 10,201,896 RGD:9068941
G Tmem79 transmembrane protein 79 JBrowse link NW_004955545 2,420,594 2,436,485 RGD:9068941
G Tnf tumor necrosis factor JBrowse link NW_004955437 117,267 119,899 RGD:9068941
G Tnfaip6 TNF alpha induced protein 6 JBrowse link NW_004955440 16,915,952 16,944,375 RGD:9068941
G Traf3ip2 TRAF3 interacting protein 2 JBrowse link NW_004955411 36,328,152 36,363,614 RGD:9068941
G Trpv3 transient receptor potential cation channel subfamily V member 3 JBrowse link NW_004955467 13,246,099 13,276,741 RGD:9068941
G Tslp thymic stromal lymphopoietin JBrowse link NW_004955418 4,041,529 4,045,534 RGD:9068941
G Vdr vitamin D receptor JBrowse link NW_004955500 6,745,725 6,798,052 RGD:9068941
G Vnn1 vanin 1 JBrowse link NW_004955436 13,238,307 13,266,800 RGD:9068941
G Wasl WASP like actin nucleation promoting factor JBrowse link NW_004955479 5,167,851 5,200,512 RGD:9068941
G Znf365 zinc finger protein 365 JBrowse link NW_004955425 15,652,373 15,675,255 RGD:9068941
atopic dermatitis 4 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Socs3 suppressor of cytokine signaling 3 JBrowse link NW_004955506 4,222,455 4,225,563 RGD:7240710
RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 10588
    sensory system disease 3722
      skin disease 1941
        Eczematous Skin Diseases 223
          atopic dermatitis 79
            Atopic Dermatitis 1 0
            MOMES Syndrome 0
            Neural Deafness with Atypical Atopic Dermatitis 0
            atopic dermatitis 2 0
            atopic dermatitis 3 0
            atopic dermatitis 4 1
            atopic dermatitis 5 0
            atopic dermatitis 6 0
            atopic dermatitis 7 0
            atopic dermatitis 8 0
            atopic dermatitis 9 0
Path 2
Term Annotations click to browse term
  disease 10588
    disease of anatomical entity 10127
      Immune & Inflammatory Diseases 2336
        immune system disease 1911
          hypersensitivity reaction disease 1169
            allergic hypersensitivity disease 476
              Immediate Hypersensitivity 372
                atopic dermatitis 79
                  Atopic Dermatitis 1 0
                  MOMES Syndrome 0
                  Neural Deafness with Atypical Atopic Dermatitis 0
                  atopic dermatitis 2 0
                  atopic dermatitis 3 0
                  atopic dermatitis 4 1
                  atopic dermatitis 5 0
                  atopic dermatitis 6 0
                  atopic dermatitis 7 0
                  atopic dermatitis 8 0
                  atopic dermatitis 9 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.